Germana Meroni

Summary

Affiliation: Telethon Institute of Genetics and Medicine
Country: Italy

Publications

  1. ncbi TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases
    Germana Meroni
    Telethon Institute of Genetics and Medicine TIGEM, Naples, Italy
    Bioessays 27:1147-57. 2005
  2. ncbi Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase
    Lucia Micale
    Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
    Eur J Hum Genet 16:1038-49. 2008
  3. ncbi Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties
    Marco Sardiello
    Telethon Institute of Genetics and Medicine, Via P, Castellino 111, 80131 Naples, Italy
    BMC Evol Biol 8:225. 2008
  4. ncbi Mig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubules
    Caterina Berti
    Telethon Institute of Genetics and Medicine, 80131 Naples, Italy
    BMC Cell Biol 5:9. 2004
  5. ncbi TRIM9 is specifically expressed in the embryonic and adult nervous system
    Caterina Berti
    Telethon Institute of Genetics and Medicine, Via P Castellino, 111, 80131, Naples, Italy
    Mech Dev 113:159-62. 2002
  6. ncbi Molecular and biochemical characterisation of a novel sulphatase gene: Arylsulfatase G (ARSG)
    Paola Ferrante
    Telethon Institute of Genetics and Medicine, Via P Castellino 111, 80131 Naples, Italy
    Eur J Hum Genet 10:813-8. 2002
  7. ncbi BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta
    Lixin Xu
    Department of Biochemistry and Molecular Biology, F Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 4799, USA
    Exp Cell Res 288:84-93. 2003
  8. ncbi Identification and biochemical characterization of an avian sulfatase homologous to the human ARSE, the gene for X-linked chondrodysplasia punctata
    Paola Ferrante
    Telethon Institute of Genetics and Medicine c o Area della Ricerca del CNR, Via P Castellino 111, Naples 80131, Italy
    Gene 336:155-61. 2004
  9. ncbi Molecular classification of nodal metastasis in primary larynx squamous cell carcinoma
    Francesco Carinci
    Department of Maxillofacial Surgery, University of Ferrara, Ferrara, Italy
    Transl Res 150:233-45. 2007

Collaborators

  • Graciana Diez-Roux
  • Marco Sardiello
  • Massimo Zollo
  • Emmanouil T Dermitzakis
  • Caterina Berti
  • Paola Ferrante
  • Andrea Ballabio
  • Silvia Messali
  • Lucia Micale
  • Francesco Carinci
  • Alexandre Reymond
  • Lixin Xu
  • Carmela Fusco
  • Giuseppe Merla
  • Bartolomeo Augello
  • Luisa M R Napolitano
  • Antonio Pastore
  • Stefano Volinia
  • Davide Valentini
  • Pio Conti
  • Diego Arcelli
  • Franco Ionna
  • Filiberto Mastrangelo
  • Anna D'Angelo
  • Rita Evangelisti
  • Stefano Tete
  • Lorenzo Lo Muzio
  • Francesca Francioso
  • Rosa Ferrentino
  • Bianca Fontanella
  • Jane P Jensen
  • Peter D'Arpa
  • Prasun K Moitra
  • Lihong Yang
  • Prasad Rallabhandi
  • Sunil Kaul
  • Allan M Weissman
  • Keiko Hashimoto

Detail Information

Publications9

  1. ncbi TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases
    Germana Meroni
    Telethon Institute of Genetics and Medicine TIGEM, Naples, Italy
    Bioessays 27:1147-57. 2005
    ..Here, we review recent data indicating that some TRIM/RBCC proteins are implicated in ubiquitination and propose that this large protein family represents a novel class of 'single protein RING finger' ubiquitin E3 ligases...
  2. ncbi Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase
    Lucia Micale
    Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
    Eur J Hum Genet 16:1038-49. 2008
    ....
  3. ncbi Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties
    Marco Sardiello
    Telethon Institute of Genetics and Medicine, Via P, Castellino 111, 80131 Naples, Italy
    BMC Evol Biol 8:225. 2008
    ..TRIM genes are involved in ubiquitylation and are implicated in a variety of human pathologies, from Mendelian inherited disorders to cancer, and are also involved in cellular response to viral infection...
  4. ncbi Mig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubules
    Caterina Berti
    Telethon Institute of Genetics and Medicine, 80131 Naples, Italy
    BMC Cell Biol 5:9. 2004
    ..Mid1 acts as an E3 ubiquitin ligase, regulating PP2A degradation on microtubules...
  5. ncbi TRIM9 is specifically expressed in the embryonic and adult nervous system
    Caterina Berti
    Telethon Institute of Genetics and Medicine, Via P Castellino, 111, 80131, Naples, Italy
    Mech Dev 113:159-62. 2002
    ..In adult brain, TRIM9 is detected in the Purkinje cells of the cerebellum, in the hippocampus, and in the cortex...
  6. ncbi Molecular and biochemical characterisation of a novel sulphatase gene: Arylsulfatase G (ARSG)
    Paola Ferrante
    Telethon Institute of Genetics and Medicine, Via P Castellino 111, 80131 Naples, Italy
    Eur J Hum Genet 10:813-8. 2002
    ..Further studies are needed to characterise the function of Arylsulfatase G, possibly revealing a novel metabolic pathway...
  7. ncbi BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta
    Lixin Xu
    Department of Biochemistry and Molecular Biology, F Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 4799, USA
    Exp Cell Res 288:84-93. 2003
    ..Thus, four protein modules found on each of these putative ubiquitin ligases, a RING, a B-box and two PHR repeats, are present on BTBD1/2 and TRIM5delta that are colocalized to cytoplasmic bodies...
  8. ncbi Identification and biochemical characterization of an avian sulfatase homologous to the human ARSE, the gene for X-linked chondrodysplasia punctata
    Paola Ferrante
    Telethon Institute of Genetics and Medicine c o Area della Ricerca del CNR, Via P Castellino 111, Naples 80131, Italy
    Gene 336:155-61. 2004
    ..The identification of the ARSE chicken gene is an important step for the study of its natural substrate and its role during development...
  9. ncbi Molecular classification of nodal metastasis in primary larynx squamous cell carcinoma
    Francesco Carinci
    Department of Maxillofacial Surgery, University of Ferrara, Ferrara, Italy
    Transl Res 150:233-45. 2007
    ..This large-scale gene expression analysis in LSCC provides information on changes in genomic activity associated with lymphonodal metastasis and identifies molecules that might prove useful as novel therapeutic targets...