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Genomes and GenesSpecies | C TassorelliSummaryCountry: Italy Publications
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Publications
Neurochemical mechanisms of nitroglycerin-induced neuronal activation in rat brain: a pharmacological investigationC Tassorelli
Neurological Institute C Mondino, University of Pavia, Italy
Neuropharmacology 36:1417-24. 1997..Nitric oxide seems to represent the most important mediator of this phenomenon. The sympathetic system and prostaglandin synthesis are also likely to be involved...
Reciprocal circuits involved in nitroglycerin-induced neuronal activation of autonomic regions and pain pathways: a double immunolabeling and tract-tracing studyC Tassorelli
University Center for Adaptive Disorders and Headache UCADH, Neurological Institute C Mondino Foundation, University of Pavia, Via Palestro, 3, 27100, Pavia, Italy
Brain Res 842:294-310. 1999..These data confirm and expand on our previous findings and demonstrate that nitroglycerin activates a complex set of structures that are functionally and structurally interconnected to articulate an integrated response...
Combined evaluation of pupillary and cardiovascular responses to cold pressor test in cluster headache patientsC Tassorelli
Headache Center and Autonomic Unit, Institute of Neurology IRCCS C Mondino Foundation, University of Pavia, Italy
Cephalalgia 18:668-74. 1998..These data suggest a systemic sympathetic hyperactivation in response to CPT in CH patients. An oculocephalic sympathetic hypofunction is possibly associated as well as an altered opioid neuromodulation...
The effects on the central nervous system of nitroglycerin--putative mechanisms and mediatorsC Tassorelli
Neurological Institute IRCCS C Mondino, University of Pavia, Italy
Prog Neurobiol 57:607-24. 1999..Double labeling immunocytochemical and neuropharmacological studies have provided information on the putative neurotransmitters and neurochemical mechanisms involved in nitroglycerin-induced neuronal activation...
Modifications of apoptosis-related protein levels in lymphocytes of patients with Parkinson's disease. The effect of dopaminergic treatmentF Blandini
Laboratory of Functional Neurochemistry, Neurological Institute C Mondino, Pavia, Italy
J Neural Transm 111:1017-30. 2004....
Alterations of the endocannabinoid system in an animal model of migraine: evaluation in cerebral areas of ratR Greco
IRCCS Neurological Institute C Mondino Foundation, University of Pavia, Pavia, Italy
Cephalalgia 30:296-302. 2010..These data strongly support the involvement of the endocannabinoid system in the modulation of nitroglycerin-induced hyperalgesia, and, possibly, in the pathophysiological mechanisms of migraine...
Parthenolide is the component of tanacetum parthenium that inhibits nitroglycerin-induced Fos activation: studies in an animal model of migraineC Tassorelli
Laboratory of Pathophysiology of Integrative Autonomic Systems, IRCCS Neurological Institute C Mondino Foundation and University Centre for the Study of Adaptive Disorder and Headache, Pavia, Italy
Cephalalgia 25:612-21. 2005..These findings strongly suggest that parthenolide is the component responsible for the biological activity of TP as regards its antimigraine effect and provide important information for future controlled clinical trials...
Functional and neurochemical changes of the gastrointestinal tract in a rodent model of Parkinson's diseaseF Blandini
Interdepartmental Research Center for Parkinson s Disease CRIMP, Neurological Institute C Mondino, Pavia, Pavia, Italy
Neurosci Lett 467:203-7. 2009....
Role of calcitonin gene-related peptide and substance P in different models of painR Greco
Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
Cephalalgia 28:114-26. 2008....
Peripheral levels of BDNF and NGF in primary headachesF Blandini
Laboratory of Functional Neurochemistry, Neurological Institute C. Mondino, Pavia, Italy
Cephalalgia 26:136-42. 2006....
A narrative review on the management of medication overuse headache: the steep road from experience to evidencePaolo Rossi
IRCCS Neurological Institute C Mondino Foundation, University Centre for Headache and Adaptive Disorders UCADH, Pavia Section, Pavia, Italy
J Headache Pain 10:407-17. 2009....
Nitroglycerin enhances cGMP expression in specific neuronal and cerebrovascular structures of the rat brainC Tassorelli
Laboratory of Pathophysiology of Integrative Autonomic Systems, University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology, Pavia, Italy
J Chem Neuroanat 27:23-32. 2004..The data obtained sustains the idea that cGMP is an important mediator of nitroglycerin effect in vascular and neuronal structures that are critical elements for the transmission of cephalic pain...
Functional changes of the basal ganglia circuitry in Parkinson's diseaseF Blandini
Neurological Institute C Mondino, Pavia, Italy
Prog Neurobiol 62:63-88. 2000..Drugs capable of antagonizing the effects of glutamate might represent, in the next future, a valuable tool for the development of new symptomatic and neuroprotective strategies for therapy of Parkinson's disease...
Electrophysiologic patterns of oral-pharyngeal swallowing in parkinsonian syndromesE Alfonsi
Spinal and Cranial Reflexes Laboratory, Department of Neurological Sciences, Universita di Pavia, Pavia, Italy
Neurology 68:583-9. 2007....
Effects of dopaminergic stimulation on peripheral markers of apoptosis: relevance to Parkinson's diseaseF Blandini
IRCCS C. Mondino, Via Palestro 3, Pavia, Italy
Neurol Sci 24:157-8. 2003..Our results show that dopaminergic stimulation is associated with complex changes in regulatory proteins of apoptosis...
Effects of acute and chronic restraint stress on nitroglycerin-induced hyperalgesia in ratsA Costa
Institute of Neurology IRCCS C Mondino, University Center for Adaptive Disorders and Headache UCADH, University of Pavia, Italy
Neurosci Lett 383:7-11. 2005....
An electrophysiological approach to the diagnosis of neurogenic dysphagia: implications for botulinum toxin treatmentE Alfonsi
Spinal and Cranial Reflexes Laboratory, Fondazione Istituto Neurologico C Mondino IRCCS, Pavia, Italy
J Neurol Neurosurg Psychiatry 81:54-60. 2010....
Medication overuse headache and applicability of the ICHD-II diagnostic criteria: 1-year follow-up study (CARE I protocol)N Ghiotto
Headache Unit and University Centre for Adaptive Disorders and Headache, Mondino Institute of Neurology Foundation, Pavia, Italy
Cephalalgia 29:233-43. 2009..In addition, the present findings point to the need for a more objective criterion to quantify headache frequency after drug withdrawal...
Reduced habituation of trigeminal reflexes in patients with episodic cluster headache during cluster periodA Perrotta
University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy
Cephalalgia 28:950-9. 2008..The lack of habituation in CH, more pronounced than in migraine, points to abnormal processing of sensory stimuli at the trigeminal level that could be driven by hypothalamic dysfunction during the cluster period...
Dynamic evaluation by TV-pupillometry of the mydriatic effect of ibopamine solution. Controlled studiesG Micieli
Department of Neurology, C Mondino Foundation, University of Pavia, Italy
Arzneimittelforschung 40:150-6. 1990..The effect of ibopamine 1% on the pupillary reflex to near vision is slight, while on the reflex to light stimulus it is essentially comparable to that of tropicamide...
The usefulness and applicability of a basic headache diary before first consultation: results of a pilot study conducted in two centresC Tassorelli
University Centre for the Study of Adaptive Disorders and Headache UCADH, IRCCS C Mondino Institute of Neurology Foundation, Pavia, Italy
Cephalalgia 28:1023-30. 2008..Specificity was 58% for M and TTH, 87% for MOH. Combined use of a diagnostic diary and clinical interview is recommended from the first consultation for headache...
Reliability of the nitroglycerin provocative test in the diagnosis of neurovascular headachesG Sances
Headache Unit, University Centre for Adaptive Disorders and Headache, IRCCS C Mondino Foundation Institute of Neurology, Pavia, Italy
Cephalalgia 24:110-9. 2004..6%, specificity 100% and accuracy 92.9%. NPT is an easy, low-cost and reliable method for supporting the diagnosis of migraine without aura and cluster headache...
Neurotensin-induced miosis: the role of dopaminergic pathwaysC Tassorelli
Department of Neurology, C Mondino Foundation, University of Pavia, Italy
Peptides 11:1309-11. 1990..Our data confirm previous observations regarding the miotic activity of neurotensin and suggest that the dopaminergic system plays an important role in the miotic effect of neurotensin...
Diagnostic issues in chronic daily headacheG Sandrini
University Center for Adaptive Disorders and Headache, C Mondino Foundation, Via Palestro, Pavia 3 27100, Italy
Curr Pain Headache Rep 5:551-6. 2001..Although some theoretic problems remain unresolved, it seems that the next revision of the IHS classification can no longer ignore the existence of CDH...
Effectiveness of a piroxicam fast dissolving formulation sublingually administered in the symptomatic treatment of migraine without auraG Nappi
Dept. of Neurology, C. Mondino Foundation, University of Pavia, Italy
Headache 33:296-300. 1993..In conclusion, Piroxicam FDDF has been shown in this preliminary study to have striking efficacy in the acute treatment of migraine. The treatment is characterized by quick onset, long duration and good tolerability...
Effects of the intrastriatal administration of selective dopaminergic agonists on Fos expression in the rat brainF Blandini
IRCCS C. Mondino, Via Palestro 3, Pavia, Italy
Neurol Sci 23:S57-8. 2002..They also provide new information on a class of drugs--the dopamine agonists--whose role in the therapeutic strategy of Parkinson's disease is continuously evolving...
Nitroglycerin-induced activation of monoaminergic transmission in the ratC Tassorelli
IRCCS Neurological Institute, C Mondino Foundation, Pavia, Italy
Cephalalgia 22:226-32. 2002..These data might therefore help to clarify the mechanisms underlying the delayed migraine attack observed in migraine sufferers after systemic administration of nitroglycerin...
