Alessandro Squizzato

Summary

Country: Italy

Publications

  1. doi request reprint Differential diagnosis of pulmonary embolism in outpatients with non-specific cardiopulmonary symptoms
    Alessandro Squizzato
    Department of Clinical Medicine, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese, Italy
    Intern Emerg Med 8:695-702. 2013
  2. doi request reprint Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia
    Alessandro Squizzato
    Research Center on Thromboembolic Disorders and Antithrombotic Therapies, Department of Clinical and ExperimentalMedicine, School of Medicine, University of Insubria, Varese, Italy
    Cochrane Database Syst Rev 4:CD006503. 2013
  3. doi request reprint Viral hepatitis and thrombosis: a narrative review
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 38:530-4. 2012
  4. doi request reprint Prognostic clinical prediction rules to identify a low-risk pulmonary embolism: a systematic review and meta-analysis
    A Squizzato
    Research Center on Thromboembolic Disorders and Antithrombotic Therapies, Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 10:1276-90. 2012
  5. ncbi request reprint Clinical review: Thyroid dysfunction and effects on coagulation and fibrinolysis: a systematic review
    A Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Clin Endocrinol Metab 92:2415-20. 2007
  6. ncbi request reprint Subclinical hypothyroidism and deep venous thrombosis. A pilot cross-sectional study
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Ospedale di Circolo, Viale Borri 57, 21100 Varese, Italy
    Thromb Haemost 97:803-6. 2007
  7. ncbi request reprint The coagulation system in endocrine disorders: a narrative review
    A Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Intern Emerg Med 2:76-83. 2007
  8. ncbi request reprint Recurrent deep venous thrombosis during optimal anticoagulation and overt hyperthyroidism: a case report
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Blood Coagul Fibrinolysis 18:801-3. 2007
  9. doi request reprint Novel risk factors for venous thromboembolism
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, UO Medicina I, Ospedale di Circolo, Varese, Italy
    Hematol Oncol Clin North Am 24:709-16, viii. 2010
  10. doi request reprint Outpatient treatment and early discharge of symptomatic pulmonary embolism: a systematic review
    A Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Eur Respir J 33:1148-55. 2009

Detail Information

Publications71

  1. doi request reprint Differential diagnosis of pulmonary embolism in outpatients with non-specific cardiopulmonary symptoms
    Alessandro Squizzato
    Department of Clinical Medicine, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese, Italy
    Intern Emerg Med 8:695-702. 2013
    ....
  2. doi request reprint Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia
    Alessandro Squizzato
    Research Center on Thromboembolic Disorders and Antithrombotic Therapies, Department of Clinical and ExperimentalMedicine, School of Medicine, University of Insubria, Varese, Italy
    Cochrane Database Syst Rev 4:CD006503. 2013
    ..In addition to the different therapeutic strategies available, an antiplatelet drug is often used to reduce thrombotic risk...
  3. doi request reprint Viral hepatitis and thrombosis: a narrative review
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 38:530-4. 2012
    ..The hemostatic state in chronic liver disease and the role of coagulation in liver fibrosis will also be discussed...
  4. doi request reprint Prognostic clinical prediction rules to identify a low-risk pulmonary embolism: a systematic review and meta-analysis
    A Squizzato
    Research Center on Thromboembolic Disorders and Antithrombotic Therapies, Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 10:1276-90. 2012
    ..A number of clinical prediction rules (CPRs) have been proposed for stratifying PE mortality risk. The aim of this systematic review was to assess the performance of prognostic CPRs in identifying a low-risk PE...
  5. ncbi request reprint Clinical review: Thyroid dysfunction and effects on coagulation and fibrinolysis: a systematic review
    A Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Clin Endocrinol Metab 92:2415-20. 2007
    ..The purpose of this systematic review is to summarize the effects of hyperthyroidism and hypothyroidism on these systems...
  6. ncbi request reprint Subclinical hypothyroidism and deep venous thrombosis. A pilot cross-sectional study
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Ospedale di Circolo, Viale Borri 57, 21100 Varese, Italy
    Thromb Haemost 97:803-6. 2007
    ..The results of this pilot study suggest an increased prevalence of subclinical hypothyroidism in patients with unDVT. The clinical relevance of these preliminary findings needs to be addressed in larger prospective studies...
  7. ncbi request reprint The coagulation system in endocrine disorders: a narrative review
    A Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Intern Emerg Med 2:76-83. 2007
    ..Also effects of pheochromocytoma, hyperprolactinaemia and hyperaldosteronism on the coagulation system have been described. It is apparent that unprovoked bleeding and thrombotic episodes can be secondary to endocrine disorders...
  8. ncbi request reprint Recurrent deep venous thrombosis during optimal anticoagulation and overt hyperthyroidism: a case report
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Blood Coagul Fibrinolysis 18:801-3. 2007
    ....
  9. doi request reprint Novel risk factors for venous thromboembolism
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, UO Medicina I, Ospedale di Circolo, Varese, Italy
    Hematol Oncol Clin North Am 24:709-16, viii. 2010
    ..In this article, the authors focus on the most promising, persistent, and potentially treatable novel risk factors...
  10. doi request reprint Outpatient treatment and early discharge of symptomatic pulmonary embolism: a systematic review
    A Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Eur Respir J 33:1148-55. 2009
    ....
  11. ncbi request reprint Recombinant activated factor VII as a general haemostatic agent: evidence-based efficacy and safety
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Curr Drug Saf 2:155-61. 2007
    ..In the last few years it has been increasingly used 'off label' in medical and surgical patients to minimise or control severe or refractory bleeding, in particular when conventional therapy failed or was judged to be insufficient...
  12. doi request reprint The influence of pituitary, adrenal, and parathyroid hormones on hemostasis and thrombosis
    Alessandro Squizzato
    Research Center on Thromboembolic Disorders and Antithrombotic Therapies, Department of Clinical Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 37:41-8. 2011
    ..However, the clinical relevance is still unproven. Until definitive evidence is available, clinicians should be aware of the possibility that endocrine disorders may be risk factors for thrombotic events...
  13. doi request reprint Thromboprophylaxis in day surgery
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Int J Surg 6:S29-30. 2008
    ....
  14. doi request reprint Diagnosis and management of venous thromboembolism: Results of a survey on current clinical practice
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Res 125:134-6. 2010
    ..We developed a standardized questionnaire to explore clinical practice patterns in the management of VTE, in particular about the use of pre-clinical probability and D-dimer testing and on the home treatment of pulmonary embolism (PE)...
  15. doi request reprint New direct thrombin inhibitors
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Intern Emerg Med 4:479-84. 2009
    ..However, only reports from clinical practice patterns over the next months and years will tell us how and when to use the new DTIs...
  16. doi request reprint Statins, fibrates, and venous thromboembolism: a meta-analysis
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Eur Heart J 31:1248-56. 2010
    ..The aim is to make a systematic review of the literature to assess the effect of lipid-lowering drugs on venous thromboembolism (VTE) occurrence...
  17. doi request reprint Antithrombotic and fibrinolytic drugs for retinal vein occlusion: a systematic review and a call for action
    A Squizzato
    Medicina I Ospedale di Circolo, Viale Borri 57, 21100 Varese, Italy
    Thromb Haemost 103:271-6. 2010
    ..No firm recommendation can be provided given the limited available evidence...
  18. doi request reprint Treatment options for deep vein thrombosis
    Alessandro Squizzato
    University of Insubria, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, Department of Clinical Medicine, U O Medicina I Ospedale di Circolo, Viale Borri 57, 21100 Varese, Italy
    Expert Opin Pharmacother 11:1069-75. 2010
    ..More recently, we have been experiencing a rapidly changing situation thanks to the development of new orally active anticoagulants...
  19. doi request reprint The new oral anticoagulants, do they change the benefit vs. risk for thromboprophylaxis in association to ambulatory surgery?
    Alessandro Squizzato
    Research Center on Thromboembolic Disorders and on Antithrombotic Therapies, Department of Clinical Medicine, University of Insubria, Varese, Italy
    Curr Opin Anaesthesiol 23:722-5. 2010
    ..Two new drug classes, the direct thrombin and factor Xa (FXa) inhibitors, have been developed with a potentially better risk-benefit profile...
  20. ncbi request reprint A case report and literature review of portal vein thrombosis associated with cytomegalovirus infection in immunocompetent patients
    A Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, 21100, Italy
    Clin Infect Dis 44:e13-6. 2007
    ..Published data suggest that CMV hepatitis and, possibly, other types of acute viral hepatitis could be a local risk factor for acute PVT...
  21. ncbi request reprint Thyroid diseases and cerebrovascular disease
    A Squizzato
    Department of Vascular Medicine, Academical Medical Center, Amsterdam, The Netherlands
    Stroke 36:2302-10. 2005
    ....
  22. ncbi request reprint Effects of human cytomegalovirus infection on the coagulation system
    Alessandro Squizzato
    Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Thromb Haemost 93:403-10. 2005
    ..Definitive conclusions, however, cannot be drawn, although the in vitro studies are convincing and offer insight in the pathogenesis...
  23. doi request reprint Incidence of thromboembolic complications in patients with atrial fibrillation or mechanical heart valves with a subtherapeutic international normalized ratio: a prospective multicenter cohort study
    Francesco Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Am J Hematol 87:384-7. 2012
    ..Given the frequent observation of subtherapeutic INR levels when monitoring vitamin K antagonists, this finding warrants additional investigation to improve the management of these patients...
  24. doi request reprint Thrombin-activatable fibrinolysis inhibitor in hypothyroidism and hyperthyroxinaemia
    Chantal J N Verkleij
    Department of Experimental Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Thromb Haemost 109:214-20. 2013
    ..The disturbed haemostatic balance in patients with hyperthyroidism might make them prone to thrombosis, while the risk for bleeding may increase in patients with hypothyroidism...
  25. pmc Increasing levels of free thyroxine as a risk factor for a first venous thrombosis: a case-control study
    Bregje van Zaane
    Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
    Blood 115:4344-9. 2010
    ..0 (95% CI, 1.1-154.1) for FT(4) levels above reference range. Our data suggest increasing levels of FT(4) to be a risk factor for VT and may have implications for both the prevention and management of this disease...
  26. doi request reprint Prolactin and venous thrombosis: indications for a novel risk factor?
    Bregje van Zaane
    Department of Internal Medicine, Slotervaart Hospital, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands
    Arterioscler Thromb Vasc Biol 31:672-7. 2011
    ..Several acquired risk factors for venous thrombosis (VT) are associated with high prolactin levels. Our goal was to investigate VT risk for different levels of prolactin...
  27. ncbi request reprint Weight gain after acute deep venous thrombosis: a prospective observational study
    Walter Ageno
    Department of Internal Medicine, Ospedale di Circolo, University of Insubria, Viale Borri 57, 21100 Varese, Italy
    Thromb Res 109:31-5. 2003
    ..Weight gain is strongly associated with an increase in metabolic and cardiovascular risk factors. The aim of this study was to assess weight changes occurring after an episode of acute deep venous thrombosis (DVT)...
  28. ncbi request reprint The initial phase of oral anticoagulation with warfarin in outpatients with deep venous thrombosis
    Walter Ageno
    Department of Internal Medicine, University of Insubria, Varese, Italy
    Blood Coagul Fibrinolysis 14:11-4. 2003
    ..039). Patients younger than 60 years old had an odds ratio for an extended treatment of 4.92 (P = 0.0057). Algorithms with different loading doses of warfarin according to age should be proposed for outpatient treatment of DVT...
  29. doi request reprint Safety of thrombolysis in cerebral venous thrombosis. A systematic review of the literature
    Francesco Dentali
    Internal Medicine, Department of Clinical Medicine, University of Insubria Ospedale di Circolo, Varese, Italy
    Thromb Haemost 104:1055-62. 2010
    ..Future studies are necessary to evaluate the safety of thrombolysis in comparison to more conservative strategies...
  30. doi request reprint Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists. A meta-analysis
    Francesco Dentali
    University of Insubria, Varese, Italy
    Thromb Haemost 106:429-38. 2011
    ..9-16.6). In conclusion, our results suggest there is a low but quantifiable risk of thromboembolism in VKA-treated patients receiving PCCs for anticoagulation reversal. These findings should be confirmed in randomised, controlled trials...
  31. ncbi request reprint Body mass index is associated with the development of the post-thrombotic syndrome
    Walter Ageno
    Department of Internal Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 89:305-9. 2003
    ..918 and p = 0.775, respectively). BMI is significantly correlated with the development of PTS. Patients with DVT should be encouraged to avoid weight gain. Reducing patient weight might be an important strategy to prevent PTS...
  32. ncbi request reprint D-dimer is not a long-term prognostic marker following acute cerebral ischemia
    Alessandro Squizzato
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Blood Coagul Fibrinolysis 17:303-6. 2006
    ..50 microg/ml was not predictive of an increased risk of subsequent events. D-dimer levels measured in the acute phase after an acute cerebrovascular event probably do not predict the long-term clinical outcome...
  33. doi request reprint Statin treatment and the risk of recurrent pulmonary embolism
    Sara Biere-Rafi
    Department of Vascular Medicine, F4 140, Academic Medical Centre, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands
    Eur Heart J 34:1800-6. 2013
    ..We examined the effect of statin therapy on the risk of recurrent pulmonary embolism (PE)...
  34. doi request reprint The effect of hyperthyroidism on procoagulant, anticoagulant and fibrinolytic factors: a systematic review and meta-analysis
    Danka J F Stuijver
    Department of Internal Medicine, Slotervaart Hospital, Louwesweg, Amsterdam, The Netherlands
    Thromb Haemost 108:1077-88. 2012
    ..We conclude that both subclinical and overt hyperthyroidism induce a prothrombotic state, which is therefore likely to be a risk factor for venous thrombosis...
  35. doi request reprint Incidence of chronic pulmonary hypertension in patients with previous pulmonary embolism
    Francesco Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Thromb Res 124:256-8. 2009
    ..We therefore carried out a prospective cohort study to assess the incidence of CTPH diagnosed with echocardiography Doppler in consecutive patients with a first episode of PE...
  36. ncbi request reprint Residual venous obstruction in patients with a single episode of deep vein thrombosis and in patients with recurrent deep vein thrombosis
    Matteo Galli
    U O Medicina I, Ospedale di Circolo, Viale Borri 57, 21100 Varese, Italy
    Thromb Haemost 94:93-5. 2005
    ..00001). The prevalence of RVO is significantly higher in patients with recurrent DVT than in patients with a single episode. This finding supports the importance of RVO as a potential marker of a persistent prothrombotic state...
  37. doi request reprint Arterial and venous thrombosis in endocrine diseases
    Bregje van Zaane
    Department of Internal Medicine, Slotervaartziekenhuis, Amsterdam, The Netherlands
    Semin Thromb Hemost 39:489-95. 2013
    ..All these endocrine diseases do have, or may have, influence either on hemostasis or on the risk of thrombotic events. Future studies are needed to establish the clinical relevance of these associations...
  38. ncbi request reprint Epidemiology and risk factors of venous thromboembolism
    Walter Ageno
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 32:651-8. 2006
    ..The presence or absence of specific risk factors may play an important role in decisions about the type (and duration) of thromboprophylaxis/anticoagulation to be used...
  39. doi request reprint Neutrophils and clinical outcomes in patients with acute coronary syndromes and/or cardiac revascularisation. A systematic review on more than 34,000 subjects
    Luigina Guasti
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 106:591-9. 2011
    ..The findings of our systematic review highlight the potential application of this inexpensive and readily available inflammatory marker for risk stratification in patients with ACS and/or cardiac revascularisation...
  40. ncbi request reprint Oral anticoagulant therapy in patients with mechanical heart valve and intracranial haemorrhage. A systematic review
    Erica Romualdi
    U O Medicina Interna I, Ospedale di Circolo, Viale Borri, 57, 21100 Varese, Italy
    Thromb Haemost 101:290-7. 2009
    ..However, well-designed studies are strongly recommended to provide better evidence...
  41. doi request reprint Use of statins and recurrence of atrial fibrillation after catheter ablation or electrical cardioversion. A systematic review and meta-analysis
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 106:363-70. 2011
    ..20). In conclusion, statins may lower the risk of AF recurrence after electrical cardioversion, but not ablation. However, this finding should be considered with caution, and larger RCTs are warranted to confirm our preliminary results...
  42. doi request reprint Hypercoagulable state in Cushing's syndrome: a systematic review
    Bregje van Zaane
    Department of Internal Medicine, Slotervaart Hospital, Louwesweg 6, Amsterdam, The Netherlands
    J Clin Endocrinol Metab 94:2743-50. 2009
    ..It has been debated whether an increased risk of venous thromboembolism (VTE) exists in patients with Cushing's syndrome...
  43. ncbi request reprint Thrombosis prophylaxis in medical patients: a retrospective review of clinical practice patterns
    Walter Ageno
    Department of Internal Medicine, University of Insubria, Italy
    Haematologica 87:746-50; discussion 250. 2002
    ..The risk of venous thromboembolism in medical patients is comparable to the risk in general surgical patients. Thromboprophylaxis is recommended for specific medical patients, but its use in clinical practice is unknown...
  44. ncbi request reprint Prophylaxis and treatment of venous thromboembolism in patients with cancer
    Walter Ageno
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Intern Emerg Med 1:260-2. 2006
  45. doi request reprint JAK2V617F mutation for the early diagnosis of Ph- myeloproliferative neoplasms in patients with venous thromboembolism: a meta-analysis
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Blood 113:5617-23. 2009
    ..JAK2 mutation is strongly associated with SVT, and routine screening of JAK2 mutation appears to be indicated in these patients...
  46. doi request reprint Application of a decision rule and a D-dimer assay in the diagnosis of pulmonary embolism
    Nadine S Gibson
    Department of Vascular Medicine, Academical Medical Center, Amsterdam, The Netherlands
    Thromb Haemost 103:849-54. 2010
    ..Furthermore, the knowledge of an abnormal D-dimer test result before seeing the patient leads to a higher CDR score. Physicians should therefore first examine patients before taking note of the D-dimer test result...
  47. doi request reprint Evaluation of right ventricular function in patients with a previous episode of pulmonary embolism using tissue Doppler imaging
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Intern Emerg Med 8:689-94. 2013
    ..002). A high proportion of patients with previous PE have echocardiographic signs of RV diastolic dysfunction 6 months after the acute phase, even in the absence of symptoms, and in the presence of normal pulmonary pressures...
  48. doi request reprint Polymorphisms of the Z protein protease inhibitor and risk of venous thromboembolism: a meta-analysis
    Francesco Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Br J Haematol 143:284-7. 2008
    ..Five studies involving 5000 patients were included. R67X and W303X mutations of Serpina10 were not associated with increased VTE risk (OR 1.63; 95% CI 0.84, 3.16 and OR 1.21; 95% CI 0.29, 4.98 respectively)...
  49. doi request reprint Certoparin for the treatment and prevention of thrombosis: pharmacological profile and results from clinical studies
    Marco P Donadini
    University of Insubria, Research Center on Thromboembolic Diseases and Antithrombotic Therapies, Department of Clinical and Experimental Medicine, Via Giucciardini 9, 21100 Varese, Italy
    Expert Opin Drug Metab Toxicol 9:901-9. 2013
    ..Several low-molecular-weight heparins are available for the prevention and treatment of venous thromboembolism and arterial thrombosis. Certoparin has been extensively tested in different clinical settings for about 20 years...
  50. ncbi request reprint Antithrombotic therapy and cancer
    Marcello Di Nisio
    Department of Vascular Medicine and of Oncology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Curr Opin Hematol 11:187-91. 2004
    ..To assess the current evidence from recent clinical trials investigating antithrombotic agents for the prophylaxis and treatment of venous thromboembolism in cancer patients and for the effects of these agents on cancer progression...
  51. doi request reprint The metabolic syndrome as a risk factor for venous and arterial thrombosis
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Semin Thromb Hemost 35:451-7. 2009
    ..A few recent studies suggest that the metabolic syndrome may also play a role in the pathogenesis of venous thromboembolism, but this latter finding needs confirmation by large clinical studies...
  52. doi request reprint Patient selection for thromboprophylaxis in medical inpatients
    Silvia Bozzato
    Department of Clinical and Experimental Medicine, Research Center on Thromboembolic Diseases and Antithrombotic Therapies, University of Insubria, Varese, Italy
    Expert Rev Cardiovasc Ther 11:1639-47. 2013
    ..In the present review, we will summarize the most recent evidence on this topic...
  53. doi request reprint Clinical approach to splanchnic vein thrombosis: risk factors and treatment
    Nicoletta Riva
    Research Center on Thromboembolic Diseases and Antithrombotic Therapies, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy
    Thromb Res 130:S1-3. 2012
    ..High quality evidence on the acute and long-term management is substantially lacking and the risk to benefit-ratio of anticoagulant therapy in SVT still needs to be better assessed...
  54. doi request reprint Long-term outcomes of patients with cerebral vein thrombosis: a multicenter study
    F Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    J Thromb Haemost 10:1297-302. 2012
    ..Little information is available on the long-term clinical outcome of cerebral vein thrombosis (CVT)...
  55. doi request reprint Seasonal and monthly variability in the incidence of venous thromboembolism. A systematic review and a meta-analysis of the literature
    Francesco Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 106:439-47. 2011
    ..Future studies are needed to better clarify the mechanisms behind this pattern...
  56. ncbi request reprint Selecting patients for home treatment of deep vein thrombosis: the problem of cancer
    Walter Ageno
    Department of Internal Medicine University of Insubria, Varese, Italy
    Haematologica 87:286-91. 2002
    ..Cancer is frequently associated with venous thromboembolism and is often considered an exclusion criterion for outpatient treatment. We investigated the impact of cancer on the outpatient management of venous thrombosis...
  57. ncbi request reprint D-dimer testing in ischemic stroke and cerebral sinus and venous thrombosis
    Alessandro Squizzato
    Department of Internal Medicine 1, University of Insubria, Varese, Italy
    Semin Vasc Med 5:379-86. 2005
    ..However, more studies are needed to confirm these recent findings as well as management studies to correctly introduce D-dimer measurement in clinical daily practice of ischemic stroke and CSVT...
  58. doi request reprint Prevalence and clinical history of incidental, asymptomatic pulmonary embolism: a meta-analysis
    F Dentali
    Department of Clinical Medicine, Insubria University, Varese, Italy
    Thromb Res 125:518-22. 2010
    ..Natural history of incidental PE remains unclear...
  59. doi request reprint Prevalence of arterial and venous thromboembolic events in diabetic patients with and without the metabolic syndrome: a cross sectional study
    F Dentali
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Res 127:299-302. 2011
    ..The presence of MS was shown to further increase the risk of arterial cardiovascular diseases (CVD) in diabetic patients. Conversely, there are no studies that have compared the risk of VTE in diabetic patients with and without the MS...
  60. ncbi request reprint An unusual case of cerebral vein thrombosis in a patient with giant cell arteritis
    Marco Donadini
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 100:513-4. 2008
  61. ncbi request reprint Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease
    Alessandro Squizzato
    Research Center on Thromboembolic Disorders and Antithrombotic Therapies, Department of Clinical Medicine, University of Insubria, Medicina 1, Viale Borri, 57, Varese, Italy, 21100
    Cochrane Database Syst Rev 1:CD005158. 2011
    ..Adding a second antiplatelet drug to aspirin may produce additional benefit for those at high risk and those with established cardiovascular disease...
  62. ncbi request reprint Prophylaxis of venous thromboembolism following laparoscopic surgery: where is the evidence?
    W Ageno
    University of Insubria, Internal Medicine, Varese, Italy
    J Thromb Haemost 3:214-5. 2005
  63. ncbi request reprint Low dose oral vitamin K to reverse acenocoumarol-induced coagulopathy: a randomized controlled trial
    W Ageno
    Department of Medicine, University of Insubria, Varese, Italy
    Thromb Haemost 88:48-51. 2002
    ..5 to 10.0. Furthermore, the use of a 1 mg dose of oral vitamin K results in an excessive risk of over-reversal of the INR...
  64. ncbi request reprint Abdominal obesity and the risk of recurrent deep vein thrombosis
    E Romualdi
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Thromb Res 119:687-90. 2007
    ..Abdominal obesity has been found to be associated with an increased risk of deep vein thrombosis (DVT). Whether patients with abdominal obesity have an increased risk of recurrence is currently unknown...
  65. ncbi request reprint Predictors of residual venous obstruction after deep vein thrombosis of the lower limbs: a prospective cohort study
    W Ageno
    Department of Internal Medicine, Ospedale di Circolo, University of Insubria, Varese, Italy
    Thromb Res 108:203-7. 2002
    ..Predictors of residual venous occlusion are unknown. We hypothesized that obesity, which causes reduced fibrinolytic activity, can predict delayed thrombus regression...
  66. doi request reprint Hypothyroidism and acquired von Willebrand's syndrome: a systematic review
    E Manfredi
    Department of Clinical Medicine, University of Insubria, Varese, Italy
    Haemophilia 14:423-33. 2008
    ..Even if bleeding episodes are mainly mild and mucocutaneous, blood transfusion, drug administration or surgical procedure may be required...
  67. ncbi request reprint Tailoring warfarin induction doses to reflect individual and disease-specific factors
    Walter Ageno
    Am J Med 118:143-4. 2005
  68. ncbi request reprint [Current issues in the initial phase of warfarin therapy]
    Alessandro Squizzato
    Recenti Prog Med 96:612-5. 2005
    ..5-5 mg), and than patients following cardiopulmonary by-pass surgery. However, further clinical studies are necessary to identify the best strategy to individualize warfarin initiation therapy...
  69. ncbi request reprint Pharmacological thromboprophylaxis in acutely ill medical patients: some work remains to be done
    Matteo Galli
    Rev Assoc Med Bras 52:376-7. 2006
  70. doi request reprint Statins and secondary prevention of ischemic and hemorrhagic stroke
    Alessandro Squizzato
    Stroke 39:e113; author reply e114. 2008
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