Research Topics
| B SposatoSummaryCountry: Italy Publications
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Publications
BMI can influence adult males' and females' airway hyperresponsiveness differentlyBruno Sposato
Unit of Pneumology, Misericordia Hospital, Via Senese 161, 58100, Grosseto, Italy
Multidiscip Respir Med 7:45. 2012..abstract:..
A regular or an intermittent treatment for asthma: the long-term effectB Sposato
U O Pneumology, Misericordia Hospital, Grosseto, Italy
Eur Rev Med Pharmacol Sci 14:1037-44. 2010..87 +/- 14.05; FEV1 95.03 +/- 13.1%), in a retrospective way over 4 years...
Influenza A H1N1 and severe asthma exacerbationB Sposato
U O Pneumologia, Azienda Ospedaliera Misericordia, Grosseto, Italy
Eur Rev Med Pharmacol Sci 14:487-90. 2010..It is necessary to use oseltamivir precociously to avoid severe complications. All asthmatic patients must regularly take their therapy especially during pandemic influenza A H1N1...
Mesalazine-induced multi-organ hypersensitivityBruno Sposato
Unità Operativa Pneumologia, Ospedale Misericordia Grosseto, Grosseto, Italy
Clin Drug Investig 30:413-7. 2010..To resolve this adverse event it is essential to discontinue mesalazine treatment...
Short term effect of a single dose of formoterol or tiotropium on the isolated nocturnal hypoxemia in stable COPD patients: a double blind randomized studyB Sposato
UOC Pneumologia, Azienda Ospedaliera Misericordia, Grosseto, Italy
Eur Rev Med Pharmacol Sci 12:203-11. 2008..On the contrary, a single dose of tiotropium seems to decrease the severity in the nocturnal desaturations in stable COPD patients probably due to the reduction in the nocturnal bronchial colinergic tone...
When should a reversibility test be performed on patients with early stages of asthma and normal spirometry?Bruno Sposato
Azienda Ospedaliera Misericordia, UO Pneumologia, Grosseto, Italy
J Asthma 45:479-83. 2008..It is improbable to find a positive reversibility test using salbutamol in patients with asthmatic symptoms and FEV(1) > 121% or FEV(1)/FVC > 110.8% or FEF(25 -75) > 110% to confirm the diagnosis of asthma...
Oral corticosteroids can improve nocturnal isolated hypoxemia in stable COPD patients with diurnal PaO2 > 60 mmHgB Sposato
UOC Pneumologia, Azienda Ospedaliera Misericordia, Grosseto, Italy
Eur Rev Med Pharmacol Sci 11:365-72. 2007....
The influence of ipratropium bromide in the recovery phase of methacholine induced-bronchospasmB Sposato
Dipartimento di Scienze Cardiovascolari e Respiratorie, Universita La Sapienza, Rome, Italy
Eur Rev Med Pharmacol Sci 9:117-23. 2005..The objective of the present study was to assess whether a pretreatment with IB may influence the subsequent phase of methacholine-induced bronchospasm relief...
[Nocturnal desaturation in chronic obstructive pulmonary disease]Bruno Sposato
Centro Universitario Broncopneumopatie Emergenti, Ospedale Forlanini, Universita La Sapienza, Roma
Recenti Prog Med 93:686-94. 2002..Since negative outcomes are possible, nocturnal oxygen desaturation must be early put in evidence and then treated with suitable drugs, correct dietetic regimen, respiratory physiotherapy and nocturnal oxygen-therapy...
Induction and recovery phases of methacholine-induced bronchoconstriction using FEV1 according to the degree of bronchial hyperresponsivenessF Mannino
Dipartimento di Scienze Cardiovascolari e Respiratorie, Sezione Malattie Respiratorie, , Rome, Italy
Lung 179:137-45. 2001....
Predictive indexes of nocturnal desaturation in COPD patients not treated with long term oxygen therapyG De Angelis
, Ospedale C. Forlanini, Roma, Italy
Eur Rev Med Pharmacol Sci 5:173-9. 2001..In these patients reduced FEV1, high BMI and/or elevated PaCO2 appear to be predictive indexes of nocturnal desaturation. A PaCO2 > 50 mm Hg is highly indicative for a nocturnal oxygen desaturation...
Reversibility test in the early stages of bronchial asthmaSalvatore Mariotta
Dipartimento di Scienze Cardiovascolari e Respiratorie, , UO Pneumologia, Azienda Ospedaliera Sant'Andrea, Rome, Italy
J Asthma 42:487-91. 2005....
Changes in monocyte phagocyting activity after multi-agent chemotherapy in non-small cell lung cancerS Mariotta
Dipartimento di Scienze Cardiovascolari e Respiratorie, Sezione Malattie Respiratorie, Policlinico Sant'Andrea, University La Sapienza, Rome, Italy
Eur Rev Med Pharmacol Sci 6:67-73. 2002..The in vitro assessment of monocyte functions may be useful to better clarify mechanisms by which anti-neoplastic agents may act on immune functions and prevent adverse side effects...
[Significant increase of incidence of cypress pollen allergy in the city of Rome]B Sposato
Dipartimento di Scienze Cardiovascolari e Respiratorie, , Roma
Recenti Prog Med 92:541. 2001..2 (DS = 13.48). This analysis wants to stress the increasing incidence of allergy toward cypressus among atopic subjects, switching from 9.3% to 30.4%, in the same urban area, during these last three years...
Comparison of the protective effect amongst anticholinergic drugs on methacholine-induced bronchoconstriction in asthmaBruno Sposato
UOC Pneumologia, Azienda Ospedaliera Misericordia, Grosseto, Italy
J Asthma 45:397-401. 2008..It's probable that the best dose of Ipratropium should be a higher one than the usual dose taken...
Time intervals (3' or 5') between dose steps can influence methacholine challenge testSalvatore Mariotta
Dipartimento Scienze Cardiovascolari e Respiratorie, Universita La Sapienza, U O Pneumologia, Azienda Ospedaliera Sant Andrea, Via di Grottarossa 1035 39, 00189 Rome, Italy
Lung 183:1-11. 2005..It is hoped that time interval between doses be standardized to ensure maximum comparability within and between subjects in challenge tests...
