Research Topics
| Morando SoffrittiSummaryCountry: Italy Publications
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Publications
Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in ratsMorando Soffritti
Cesare Maltoni Cancer Research Center, European Ramazzini Foundation of Oncology and Environmental Sciences, Bologna, Italy
Environ Health Perspect 115:1293-7. 2007....
Potential carcinogenic effects of world trade center dust after intratracheal instillation to Sprague-Dawley rats: first observationM Soffritti
Cesare Maltoni Cancer Research Center, Ramazzini Institute, Bologna, Italy
Am J Ind Med 56:155-62. 2013..It is well known that long-term carcinogenic bioassays on rodents can predict the potential carcinogenic effects of chemical and physical agents for humans...
Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss miceMorando Soffritti
Cesare Maltoni Cancer Research Center, Ramazzini Institute, Bentivoglio, Bologna, Italy
Am J Ind Med 53:1197-206. 2010..In previous lifespan experiments conducted on Sprague-Dawley rats we have shown that APM is a carcinogenic agent in multiple sites and that its effects are increased when exposure starts from prenatal life...
Consequences of exposure to carcinogens beginning during developmental lifeMorando Soffritti
Cesare Maltoni Cancer Research Center, European Ramazzini Foundation of Oncology and Environmental Sciences, Bologna, Italy
Basic Clin Pharmacol Toxicol 102:118-24. 2008..Moreover, when comparing prenatal and postnatal exposure, the data demonstrate that the development of cancers may appear earlier in life...
Results of long-term carcinogenicity bioassay on vinyl acetate monomer in Sprague-Dawley ratsFranco Minardi
Cancer Research Center, European Ramazzini Foundation for Oncology and Environmental Sciences, Bologna, Italy
Ann N Y Acad Sci 982:106-22. 2002..VAM was found to cause an increase in total malignant tumors and in carcinomas and/or precursor lesions of the oral cavity, lips, tongue, esophagus, and forestomach. Based on these data, VAM must be considered a multipotent carcinogen...
Results of long-term carcinogenicity bioassay on Sprague-Dawley rats exposed to aspartame administered in feedFiorella Belpoggi
Cesare Maltoni Cancer Research Center, European Foundation of Oncology and Environmental Sciences B. Ramazzini, 40010 Bentivoglio, Bologna, Italy
Ann N Y Acad Sci 1076:559-77. 2006..05). The results of this mega-experiment indicate that APM, in the tested experimental conditions, is a multipotential carcinogenic agent...
Results of long-term carcinogenicity bioassays on tert-amyl-methyl-ether (TAME) and di-isopropyl-ether (DIPE) in ratsFiorella Belpoggi
Cancer Research Center, European Ramazzini Foundation for Oncology and Environmental Sciences, Bologna, Italy
Ann N Y Acad Sci 982:70-86. 2002..At the end of the treatment period, all animals were kept under observation until spontaneous death. Under these test conditions, TAME and DIPE were found to be potential carcinogenic agents for various organs and tissues...
Results of long-term experimental studies on the carcinogenicity of ethylene-bis-dithiocarbamate (Mancozeb) in ratsFiorella Belpoggi
Cancer Research Center, European Ramazzini Foundation for Oncology and Environmental Sciences, Bologna, Italy
Ann N Y Acad Sci 982:123-36. 2002..On the basis of these data, Mancozeb must be considered a multipotent carcinogenic agent...
Results of long-term experimental studies on the carcinogenicity of formaldehyde and acetaldehyde in ratsMorando Soffritti
Cancer Research Center, European Ramazzini Foundation for Oncology and Environmental Sciences, Bologna, Italy
Ann N Y Acad Sci 982:87-105. 2002..Formaldehyde and acetaldehyde were found to produce an increase in total malignant tumors in the treated groups and showed specific carcinogenic effects on various organs and tissues...
Results of long-term carcinogenicity bioassays on Coca-Cola administered to Sprague-Dawley ratsFiorella Belpoggi
Cesare Maltoni Cancer Research Center, European Foundation for Oncology and Environmental Siences B. Ramazzini, 40010 Bentivoglio, Italy
Ann N Y Acad Sci 1076:736-52. 2006..On the basis of the results of this study, excessive consumption of regular soft-drinks should be generally discouraged, in particular for children and adolescents...
Results of a long-term carcinogenicity bioassay on Sprague-Dawley rats exposed to sodium arsenite administered in drinking waterMorando Soffritti
Cesare Maltoni Cancer Research Center, European Foundation of Oncology and Environmental Sciences B Ramazzini, 40010 Bentivoglio, Bologna, Italy
Ann N Y Acad Sci 1076:578-91. 2006..Notably, an elevated incidence of these types of oncological lesions is also observed among people living in geographical areas where As is present at higher concentrations in drinking water...
First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley ratsMorando Soffritti
Cesare Maltoni Cancer Research Center, European Ramazzini Foundation of Oncology and Environmental Sciences, Bologna, Italy
Environ Health Perspect 114:379-85. 2006..On the basis of these results, a reevaluation of the present guidelines on the use and consumption of APM is urgent and cannot be delayed...
[The role of scientific research in the identification of occupational carcinogenic agents: the contribution of the Cesare Maltoni Cancer research center of the European Ramazzini Foundation]Morando Soffritti
Centro di ricerca sul cancro Cesare Maltoni, Fondazione europea di oncologia e scienze ambientali, Bologna, Italia
Epidemiol Prev 33:57-67. 2009....
Results of long-term experimental studies on the carcinogenicity of methyl alcohol and ethyl alcohol in ratsMorando Soffritti
Cancer Research Center, European Ramazzini Foundation for Oncology and Environmental Sciences, Bologna, Italy
Ann N Y Acad Sci 982:46-69. 2002..In addition to causing other tumors, ethyl alcohol induced malignant tumors of the oral cavity, tongue, and lips. These sites have been shown to be target organs in man by epidemiologic studies...
Effects of different electromagnetic fields on circadian rhythms of some haematochemical parameters in ratsLaura Contalbrigo
European Foundation of Oncology and Environmental Sciences B Ramazzini, Bologna, Italy
Biomed Environ Sci 22:348-53. 2009..To investigate the effects of different electromagnetic fields on some haematochemical parameters of circadian rhythms in Sprague-Dawley rats...
Ramazzini Foundation cancer program: history and major projects, life-span carcinogenicity bioassay design, chemicals studied, and resultsMorando Soffritti
Cancer Research Center, European Ramazzini Foundation for Oncology and Environmental Sciences, Bologna, Italy
Ann N Y Acad Sci 982:26-45. 2002..Many of the results achieved have led to the introduction of norms and measures of primary prevention...
