Mauro Serafini

Summary

Country: Italy

Publications

  1. ncbi request reprint Effect of acute ingestion of fresh and stored lettuce (Lactuca sativa) on plasma total antioxidant capacity and antioxidant levels in human subjects
    Mauro Serafini
    Antioxidant Research Laboratory at the Unit of Human Nutrition, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione INRAN, Rome, Italy
    Br J Nutr 88:615-23. 2002
  2. ncbi request reprint Understanding the association between dietary antioxidants, redox status and disease: is the Total Antioxidant Capacity the right tool?
    Mauro Serafini
    Antioxidant Research Laboratory, Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
    Redox Rep 9:145-52. 2004
  3. doi request reprint Antioxidant activity of blueberry fruit is impaired by association with milk
    Mauro Serafini
    Antioxidant Research Laboratory, Unit of Human Nutrition, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, 00178 Rome, Italy
    Free Radic Biol Med 46:769-74. 2009
  4. doi request reprint Flavonoids as anti-inflammatory agents
    Mauro Serafini
    Antioxidant Research Laboratory, INRAN, Via Ardeatina 546, 00178 Rome, Italy
    Proc Nutr Soc 69:273-8. 2010
  5. ncbi request reprint Consumption of mixed fruit-juice drink and vitamin C reduces postprandial stress induced by a high fat meal in healthy overweight subjects
    Ilaria Peluso
    CRA ex INRAN, Via Ardeatina, 546, 00178 Rome, Italy
    Curr Pharm Des 20:1020-4. 2014
  6. doi request reprint The Role of polyphenols in the modulation of plasma Non-Enzymatic Antioxidant Capacity (NEAC)
    Mauro Serafini
    Antioxidant Research Laboratory, National Institute for Food and Nutrition Research, IT 00178 Rome, Italy
    Int J Vitam Nutr Res 82:228-32. 2012
  7. doi request reprint Redox ingredients for oxidative stress prevention: the unexplored potentiality of coffee
    Mauro Serafini
    Antioxidant Research Laboratory, Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
    Clin Dermatol 27:225-9. 2009
  8. ncbi request reprint Modulation of plasma non enzimatic antioxidant capacity (NEAC) by plant foods: the role of polyphenols
    M Serafini
    Antioxidant Research Laboratory at the Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
    Curr Top Med Chem 11:1821-46. 2011
  9. ncbi request reprint Redox molecules and cancer prevention: the importance of understanding the role of the antioxidant network
    Mauro Serafini
    Antioxidant Research Laboratory at the Unit of Human Nutritional, National Institute for Food and Nutrition Research, Rome, Italy
    Nutr Cancer 56:232-40. 2006
  10. doi request reprint A new flow cytometry method to measure oxidative status: the Peroxidation of Leukocytes Index Ratio (PLIR)
    Ilaria Peluso
    Agricultural Research Council CRA, ex National Institute for Food and Nutrition Research INRAN, Rome, Italy
    J Immunol Methods 390:113-20. 2013

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Effect of acute ingestion of fresh and stored lettuce (Lactuca sativa) on plasma total antioxidant capacity and antioxidant levels in human subjects
    Mauro Serafini
    Antioxidant Research Laboratory at the Unit of Human Nutrition, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione INRAN, Rome, Italy
    Br J Nutr 88:615-23. 2002
    ..Further research is needed to develop post-harvesting techniques able to preserve the bioactive molecule content of plant food...
  2. ncbi request reprint Understanding the association between dietary antioxidants, redox status and disease: is the Total Antioxidant Capacity the right tool?
    Mauro Serafini
    Antioxidant Research Laboratory, Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
    Redox Rep 9:145-52. 2004
    ..Finally, the feasibility of the 'TAC concept' as an innovative tool for investigating the association between diet and oxidative stress is discussed...
  3. doi request reprint Antioxidant activity of blueberry fruit is impaired by association with milk
    Mauro Serafini
    Antioxidant Research Laboratory, Unit of Human Nutrition, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, 00178 Rome, Italy
    Free Radic Biol Med 46:769-74. 2009
    ..001). The ingestion of blueberries in association with milk, thus, impairs the in vivo antioxidant properties of blueberries and reduces the absorption of caffeic acid...
  4. doi request reprint Flavonoids as anti-inflammatory agents
    Mauro Serafini
    Antioxidant Research Laboratory, INRAN, Via Ardeatina 546, 00178 Rome, Italy
    Proc Nutr Soc 69:273-8. 2010
    ..Human trials with appropriate placebo and pure flavonoid molecules are needed to clarify if flavonoids represent ancillary ingredients or key molecules involved in the anti-inflammatory properties of plant foods...
  5. ncbi request reprint Consumption of mixed fruit-juice drink and vitamin C reduces postprandial stress induced by a high fat meal in healthy overweight subjects
    Ilaria Peluso
    CRA ex INRAN, Via Ardeatina, 546, 00178 Rome, Italy
    Curr Pharm Des 20:1020-4. 2014
    ..Ingestion of a fruit-juice drink reduce markers of postprandial stress induced by a HFM. ..
  6. doi request reprint The Role of polyphenols in the modulation of plasma Non-Enzymatic Antioxidant Capacity (NEAC)
    Mauro Serafini
    Antioxidant Research Laboratory, National Institute for Food and Nutrition Research, IT 00178 Rome, Italy
    Int J Vitam Nutr Res 82:228-32. 2012
    ..This work will discuss the role of polyphenols from galenic preparation, food extracts, and selected dietary sources as modulators of plasma NEAC in humans...
  7. doi request reprint Redox ingredients for oxidative stress prevention: the unexplored potentiality of coffee
    Mauro Serafini
    Antioxidant Research Laboratory, Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
    Clin Dermatol 27:225-9. 2009
    ..In this contribution after describing the main contributors to dietary TAC for different plant food group, we will discuss the potentiality of coffee as a source of "ready to drink" reducing equivalents...
  8. ncbi request reprint Modulation of plasma non enzimatic antioxidant capacity (NEAC) by plant foods: the role of polyphenols
    M Serafini
    Antioxidant Research Laboratory at the Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
    Curr Top Med Chem 11:1821-46. 2011
    ..The available evidence from human intervention studies on the role of plant foods as modulators of plasma/serum NEAC and the involvement of PP will be presented and critically discussed...
  9. ncbi request reprint Redox molecules and cancer prevention: the importance of understanding the role of the antioxidant network
    Mauro Serafini
    Antioxidant Research Laboratory at the Unit of Human Nutritional, National Institute for Food and Nutrition Research, Rome, Italy
    Nutr Cancer 56:232-40. 2006
    ..The feasibility of TAC assessment as an innovative tool for investigating the association between dietary antioxidants, oxidative stress, and cancer will be also discussed...
  10. doi request reprint A new flow cytometry method to measure oxidative status: the Peroxidation of Leukocytes Index Ratio (PLIR)
    Ilaria Peluso
    Agricultural Research Council CRA, ex National Institute for Food and Nutrition Research INRAN, Rome, Italy
    J Immunol Methods 390:113-20. 2013
    ..A complex relationship between immune system and metabolic pathway exists and can induce oxidative stress. The objective of this study was to design a new methodology allowing the measurement of oxidative status of leukocytes...
  11. doi request reprint Fruit juice drinks prevent endogenous antioxidant response to high-fat meal ingestion
    Cristiana Miglio
    Agricultural Research Council CRA, Via Ardeatina 546, 00178 Rome, Italy
    Br J Nutr 111:294-300. 2014
    ..In conclusion, the increase in UA and SH levels induced by HFM as part of an endogenous antioxidant response to postprandial stress can be prevented by the concomitant ingestion of antioxidant-rich fruit juice drinks. ..
  12. ncbi request reprint High fat meal increase of IL-17 is prevented by ingestion of fruit juice drink in healthy overweight subjects
    Ilaria Peluso
    Antioxidant Research Laboratory, INRAN Via Ardeatina 546, 00178 Rome, Italy
    Curr Pharm Des 18:85-90. 2012
    ..037). We provided, for the first time, evidence on the role of diet in modulating IL-17 production in healthy overweight subjects...
  13. doi request reprint Biomarkers of antioxidant status following ingestion of green teas at different polyphenol concentrations and antioxidant capacity in human volunteers
    Monia Pecorari
    Antioxidant Research Laboratory, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, Rome, Italy
    Mol Nutr Food Res 54:S278-83. 2010
    ..6 and 1.4 g/L. An evidence for a linear correlation between GTFT antioxidant content and the extent of the antioxidant effect in vivo has been provided...
  14. doi request reprint Antioxidant and inflammatory response following high-fat meal consumption in overweight subjects
    Cristiana Miglio
    Functional Food and Metabolic Stress Prevention Program, National Institute for Food and Nutrition Research INRAN, Via Ardeatina 546, 00178, Rome, Italy
    Eur J Nutr 52:1107-14. 2013
    ..The objective of this study was to evaluate the inflammatory and antioxidant response of the body to the acute ingestion of a high-fat meal (HFM)...
  15. ncbi request reprint Plasma antioxidants from chocolate
    Mauro Serafini
    Antioxidant Research Laboratory, Unit of Human Nutrition, National Institute for Food and Nutrition Research, Via Ardeatina 546, 00178 Rome, Italy
    Nature 424:1013. 2003
  16. ncbi request reprint Total antioxidant capacity of spices, dried fruits, nuts, pulses, cereals and sweets consumed in Italy assessed by three different in vitro assays
    Nicoletta Pellegrini
    Antioxidant Research Laboratory at the Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
    Mol Nutr Food Res 50:1030-8. 2006
    ..The complete TAC database could be utilized to properly investigate the role of dietary antioxidants in disease prevention...
  17. doi request reprint Effect of flavonoids on circulating levels of TNF-α and IL-6 in humans: a systematic review and meta-analysis
    Ilaria Peluso
    Agricultural Research Council CRA, ex National Institute for Food and Nutrition Research INRAN, Rome, Italy
    Mol Nutr Food Res 57:784-801. 2013
    ..011) and random (MD (95% CI): TNF-α -0.783 (-1.476, -0.090), p = 0.027; IL-6, -0.556 (-1.062, -0.050), p = 0.031) effect models. High-quality placebo-controlled trials are needed in order to identify flavonoids as the active ingredients...
  18. ncbi request reprint Oxidative stress in atherosclerosis development: the central role of LDL and oxidative burst
    Ilaria Peluso
    Functional Food and Metabolic Stress Prevention Program, Agricultural Research Council CRA, ex National Institute for Food and Nutrition Research INRAN, Rome, Italy
    Endocr Metab Immune Disord Drug Targets 12:351-60. 2012
    ..Understanding the relationship between oxLDL and leukocyte oxidative burst helps to explain the involvement of innate immune responses in the early phases of atherosclerosis. The present review focuses on this interplay...
  19. ncbi request reprint Total antioxidant potential of fruit and vegetables and risk of gastric cancer
    Mauro Serafini
    Antioxidant Research Laboratory, Unit of Human Nutrition, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione INRAN, Rome, Italy
    Gastroenterology 123:985-91. 2002
    ..We investigated whether the total dietary antioxidant potential of fruit and vegetables is an appropriate means of estimating the antioxidant impact on gastric cancer risk in a large population-based study...
  20. doi request reprint Effect of plant foods and beverages on plasma non-enzymatic antioxidant capacity in human subjects: a meta-analysis
    Daniele Lettieri-Barbato
    Food and Nutrition Unit, IRCCS San Raffaele Pisana, via della Pisana 235, Rome, Italy
    Br J Nutr 109:1544-56. 2013
    ..This is particularly evident in the presence of oxidative stress-related risk factors...
  21. doi request reprint Dietary total antioxidant capacity and gastric cancer risk in the European prospective investigation into cancer and nutrition study
    Mauro Serafini
    Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, Rome, Italy
    Int J Cancer 131:E544-54. 2012
    ..lowest quintile: adjusted HR 0.4; 95%CI (0.21-0.75) p < 0.05); no association was observed for TRAP. Dietary antioxidant capacity intake from different sources of plant foods is associated with a reduction in the risk of GC...
  22. doi request reprint Lymphocytes as internal standard in oxidative burst analysis by cytometry: a new data analysis approach
    Ilaria Peluso
    Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione INRAN, Rome, Italy
    J Immunol Methods 379:61-5. 2012
    ..In addition, this method is sensitive to differences in healthy subjects due to sub-pathological conditions, such as hypercholesterolemia...
  23. doi request reprint The European role on traditional herbal medicinal products and traditional plant food supplements
    Mauro Serafini
    Department of Environmental Biology, Sapienza University of Rome, Rome, Italy
    J Clin Gastroenterol 46:S93-4. 2012
    ....
  24. ncbi request reprint Effect of changes in fruit and vegetable intake on plasma antioxidant defenses in humans
    Mauro Serafini
    Am J Clin Nutr 81:531-2; author reply 532-4. 2005
  25. ncbi request reprint The validity and reproducibility of food-frequency questionnaire-based total antioxidant capacity estimates in Swedish women
    Susanne Rautiainen
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    Am J Clin Nutr 87:1247-53. 2008
    ..Total antioxidant capacity (TAC) provides an assessment of antioxidant activity and synergistic interactions of redox molecules in foods and plasma...
  26. ncbi request reprint Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays
    Nicoletta Pellegrini
    Department of Public Health, University of Parma, Parma, Italy
    J Nutr 133:2812-9. 2003
    ..Such data, coupled with an appropriate questionnaire to estimate antioxidant intake, will allow the investigation of the relation between dietary antioxidants and oxidative stress-induced diseases...
  27. doi request reprint Bioavailability of pelargonidin-3-O-glucoside and its metabolites in humans following the ingestion of strawberries with and without cream
    William Mullen
    Plant Products and Human Nutrition Group, Graham Kerr Building, Division of Environmental and Evolutionary Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom
    J Agric Food Chem 56:713-9. 2008
    ..In keeping with these observations, measurement of plasma paracetamol and breath hydrogen revealed that cream delayed gastric emptying and extended mouth to cecum transit time...
  28. ncbi request reprint Endemic species of sardo-corso-balearic area: molecular composition and biological assay of Teucrium
    Ferruccio Poli
    Dipartimento di Biologia Sperimentale ed Evoluzionistica, Universita di Bologna, 40126 Bologna, Italy
    Nat Prod Res 21:1061-6. 2007
    ..The polar extracts showed antioxidant activity in vitro. Verbascoside and arabinosyl-verbascoside were isolated and identified. Their concentrations were in connection to the antioxidant activity...
  29. ncbi request reprint Total antioxidant capacity of the diet is inversely and independently related to plasma concentration of high-sensitivity C-reactive protein in adult Italian subjects
    Furio Brighenti
    Department of Public Health, University of Parma, Parma, Italy
    Br J Nutr 93:619-25. 2005
    ..This could be of particular significance for subjects with high blood pressure...
  30. ncbi request reprint Effect on rat arterial blood pressure of chemically generated peroxyl radicals and protection by antioxidants
    Ilaria Peluso
    Department of Pharmacology of Natural Substances and General Physiology, La Sapienza University, P le Aldo Moro 5, 00185 Rome, Italy
    J Nutr Biochem 15:323-7. 2004
    ..Other experiments are needed to clarify the role played by oxidative potentials on blood pressure and the mechanism of action of nutritional antioxidants...
  31. ncbi request reprint Mechanism of vitamin E inhibition of cyclooxygenase activity in macrophages from old mice: role of peroxynitrite
    Alison A Beharka
    Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Free Radic Biol Med 32:503-11. 2002
    ..These findings have important implications for designing interventions to reverse and/or delay age-associated dysregulation of immune and inflammatory responses and diseases associated with them...