Giuseppe Seghieri

Summary

Country: Italy

Publications

  1. ncbi Oral contraceptives modify DNA methylation and monocyte-derived macrophage function
    Ilaria Campesi
    National Laboratory of Sex Gender Medicine of the National Institute of Biostructures and Biosystems, Osilo, Italy
    Biol Sex Differ 3:4. 2012
  2. ncbi Gender effect on the relation between diabetes and hospitalization for heart failure
    C Seghieri
    Scuola Superiore S Anna, MES Laboratory, University of Pisa, Pisa, Italy
    Exp Clin Endocrinol Diabetes 120:51-5. 2012
  3. ncbi Plasma and platelet ascorbate pools and lipid peroxidation in insulin-dependent diabetes mellitus
    G Seghieri
    Spedali Riuniti, Pistoia, Italy
    Eur J Clin Invest 28:659-63. 1998
  4. ncbi Does parity increase insulin resistance during pregnancy?
    G Seghieri
    Department of Internal Medicine, Spedali Riuniti, Via Monte Sabotino 96 A, 51100 Pistoia, Italy
    Diabet Med 22:1574-80. 2005
  5. ncbi Stroke is related to lower serum thyrotropin levels in patients with diabetes mellitus
    Giuseppe Seghieri
    Department of Internal Medicine, Spedali Riuniti, Via Monte Sabotino 96 A, 51100 Pistoia, Italy
    Diabetes Res Clin Pract 62:203-9. 2003
  6. ncbi Gender modulates the relationship between body weight and plasma glucose in overweight or obese subjects
    Giuseppe Seghieri
    Department of Internal Medicine, Spedali Riuniti, Viale Matteotti 9 D, 51100 Pistoia, Italy
    Diabetes Res Clin Pract 80:134-8. 2008
  7. ncbi Long term predictors of post-partum glucose metabolism in women with gestational diabetes mellitus
    G Seghieri
    Department of Internal Medicine, Spedali Riuniti, Pistoia, Italy
    Exp Clin Endocrinol Diabetes 118:485-9. 2010
  8. ncbi Relationship between gestational diabetes mellitus and low maternal birth weight
    Giuseppe Seghieri
    Department of Internal Medicine, Spedali Riuniti, Pistoia, Italy Department of Pharmacology, University of Sassari, Sassari, Italy
    Diabetes Care 25:1761-5. 2002
  9. ncbi Platelet antioxidant enzymes in insulin-dependent diabetes mellitus
    G Seghieri
    U O di Medicina Interna e Sezione di Diabetologia, Spedali Riuniti, Pistoia, Italy
    Clin Chim Acta 309:19-23. 2001
  10. ncbi Relationship between metabolic glycaemic control and platelet content of glutathione and its related enzymes, in insulin-dependent diabetes mellitus
    G Seghieri
    U O di Medicina Interna e Sezione di Diabetologia, Spedali Riuniti, Pistoia, Italy
    Clin Chim Acta 299:109-17. 2000

Collaborators

Detail Information

Publications28

  1. ncbi Oral contraceptives modify DNA methylation and monocyte-derived macrophage function
    Ilaria Campesi
    National Laboratory of Sex Gender Medicine of the National Institute of Biostructures and Biosystems, Osilo, Italy
    Biol Sex Differ 3:4. 2012
    ..abstract:..
  2. ncbi Gender effect on the relation between diabetes and hospitalization for heart failure
    C Seghieri
    Scuola Superiore S Anna, MES Laboratory, University of Pisa, Pisa, Italy
    Exp Clin Endocrinol Diabetes 120:51-5. 2012
    ..However, since the comparison among sexes of heart failure prevalence in diabetic patients remains limited, this study is aimed at expanding the information about this point...
  3. ncbi Plasma and platelet ascorbate pools and lipid peroxidation in insulin-dependent diabetes mellitus
    G Seghieri
    Spedali Riuniti, Pistoia, Italy
    Eur J Clin Invest 28:659-63. 1998
    ....
  4. ncbi Does parity increase insulin resistance during pregnancy?
    G Seghieri
    Department of Internal Medicine, Spedali Riuniti, Via Monte Sabotino 96 A, 51100 Pistoia, Italy
    Diabet Med 22:1574-80. 2005
    ..To study the effect of parity on impairment of insulin sensitivity during pregnancy and on the risk of gestational diabetes (GDM)...
  5. ncbi Stroke is related to lower serum thyrotropin levels in patients with diabetes mellitus
    Giuseppe Seghieri
    Department of Internal Medicine, Spedali Riuniti, Via Monte Sabotino 96 A, 51100 Pistoia, Italy
    Diabetes Res Clin Pract 62:203-9. 2003
    ..On this basis we investigated whether stroke is associated with altered thyrotropin concentrations in a hospitalised population categorised for the presence of diabetes...
  6. ncbi Gender modulates the relationship between body weight and plasma glucose in overweight or obese subjects
    Giuseppe Seghieri
    Department of Internal Medicine, Spedali Riuniti, Viale Matteotti 9 D, 51100 Pistoia, Italy
    Diabetes Res Clin Pract 80:134-8. 2008
    ....
  7. ncbi Long term predictors of post-partum glucose metabolism in women with gestational diabetes mellitus
    G Seghieri
    Department of Internal Medicine, Spedali Riuniti, Pistoia, Italy
    Exp Clin Endocrinol Diabetes 118:485-9. 2010
    ..The question asked by this study was whether β-cell function expressed by insulin secretion/sensitivity measured during pregnancy in women with gestational diabetes (GDM) predicts post-partum long-term derangement in glucose metabolism...
  8. ncbi Relationship between gestational diabetes mellitus and low maternal birth weight
    Giuseppe Seghieri
    Department of Internal Medicine, Spedali Riuniti, Pistoia, Italy Department of Pharmacology, University of Sassari, Sassari, Italy
    Diabetes Care 25:1761-5. 2002
    ..To study the relationship between low birth weight and the presence of gestational diabetes mellitus (GDM) or peripheral insulin resistance during pregnancy...
  9. ncbi Platelet antioxidant enzymes in insulin-dependent diabetes mellitus
    G Seghieri
    U O di Medicina Interna e Sezione di Diabetologia, Spedali Riuniti, Pistoia, Italy
    Clin Chim Acta 309:19-23. 2001
    ..Likewise, the role of these intracellular enzymatic scavengers against the oxidative stress of diabetes-associated microangiopathic complications is unknown...
  10. ncbi Relationship between metabolic glycaemic control and platelet content of glutathione and its related enzymes, in insulin-dependent diabetes mellitus
    G Seghieri
    U O di Medicina Interna e Sezione di Diabetologia, Spedali Riuniti, Pistoia, Italy
    Clin Chim Acta 299:109-17. 2000
    ....
  11. ncbi Taurine in women with a history of gestational diabetes
    Giuseppe Seghieri
    Department of Internal Medicine, Spedali Riuniti, Viale Matteotti 19, 51100 Pistoia, Italy
    Diabetes Res Clin Pract 76:187-92. 2007
    ....
  12. ncbi Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes
    Elza Muscelli
    Department of Internal Medicine, University of Pisa School of Medicine, 56100 Pisa, Italy
    J Clin Endocrinol Metab 97:2818-26. 2012
    ..Dipeptidyl peptidase IV (DPP-4) inhibitors improve glycemic control in patients with type 2 diabetes. The underlying mechanisms (incretin effect, β-cell function, endogenous glucose production) are not well known...
  13. ncbi Taurine transporter gene expression in peripheral mononuclear blood cells of type 2 diabetic patients
    Loria Bianchi
    Department of Clinical Chemistry, Spedali Riuniti, Pistoia, Italy
    Amino Acids 42:2267-74. 2012
    ....
  14. ncbi Serum homocysteine levels are increased in women with gestational diabetes mellitus
    Giuseppe Seghieri
    Department of Internal Medicine, Spedali Riuniti, Pistoia, Italy
    Metabolism 52:720-3. 2003
    ....
  15. ncbi Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients
    Elza Muscelli
    Department of Internal Medicine, Consiglio Nazionale delle Ricerche CNR, Institute of Clinical Physiology, University of Pisa, Italy
    Diabetes 57:1340-8. 2008
    ..To quantitate the separate impact of obesity and hyperglycemia on the incretin effect (i.e., the gain in beta-cell function after oral glucose versus intravenous glucose)...
  16. ncbi 1-Hour OGTT Plasma Glucose as a Marker of Progressive Deterioration of Insulin Secretion and Action in Pregnant Women
    Alessandra Ghio
    Section of Metabolic Diseases and Diabetes, Department of Endocrinology and Metabolism, AOUP Pisa, University of Pisa, Ospedale Cisanello, Via Paradisa, 56124 Pisa, Italy
    Int J Endocrinol 2012:460509. 2012
    ..7%) and sensitivity (HOMA-R: +15%) indexes were still apparent (all P < 0.001). Progressive increase in 1-hour OGTT is associated with deterioration of glucose tolerance and alterations in indexes of insulin action and secretion...
  17. ncbi Normal glucose tolerance and gestational diabetes mellitus: what is in between?
    Graziano Di Cianni
    Department of Endocrinology and Metabolism, Section of Diabetes and Metabolic Diseases, University of Pisa, 56126 Pisa, Italy
    Diabetes Care 30:1783-8. 2007
    ....
  18. ncbi Improvement of diabetic foot care after the Implementation of the International Consensus on the Diabetic Foot (ICDF): results of a 5-year prospective study
    Roberto Anichini
    Division of Diabetes and Diabetes Foot Unit, General Hospital of Pistoia AUSL n 3, Pistoia, Italy
    Diabetes Res Clin Pract 75:153-8. 2007
    ..This study shows the advantages of prospective data collection, demonstrating that the implementation of the International Consensus on the Diabetic Foot can improve foot care in diabetes...
  19. ncbi Taurine supplementation and diabetes mellitus
    Flavia Franconi
    Centre for Biotechnology Development, University of Sassari, Sassari, Italy
    Curr Opin Clin Nutr Metab Care 9:32-6. 2006
    ..One form of experiment has included the possibility that perinatal taurine administration could prevent diabetes mellitus and/or insulin resistance...
  20. ncbi Influence of gestational diabetes on the long-term control of glucose tolerance
    G Seghieri
    Division of Internal Medicine, Spedali Riuniti, Pistoia, Italy
    Diabetologia 50:2234-8. 2007
    ..Gestational diabetes (GDM) carries a high risk of subsequent diabetes. We asked what impact prior GDM has on beta cell function and insulin action in women who maintain normal glucose tolerance (NGT) for a long time...
  21. ncbi Usual versus tight control of systolic blood pressure in non-diabetic patients with hypertension (Cardio-Sis): an open-label randomised trial
    Paolo Verdecchia
    Division of Cardiology, Hospital S Maria della Misericordia, Perugia, Italy
    Lancet 374:525-33. 2009
    ..We tested the hypothesis that tight control compared with usual control of systolic blood pressure would be beneficial in such patients...
  22. ncbi Gender difference in the relation blood pressure-left ventricular mass and geometry in newly diagnosed arterial hypertension
    Franco Cipollini
    Department of Internal Medicine, Spedali Riuniti, Viale Matteotti 9 D, 51100 Pistoia, Italy
    Blood Press 21:255-64. 2012
    ..LVM variance explained by ABPM SBP was much higher in females than in males. RWT, expressing concentric LVM remodelling was, conversely, more related to BP increase in males...
  23. ncbi Effect of low doses of ethanol on platelet function in long-life abstainers and moderate-wine drinkers
    Mauro Miceli
    Department of Pharmacology, University of Sassari, Via Muroni 23a, 07100 Sassari, Italy
    Life Sci 73:1557-66. 2003
    ..However, this observation may or may not influence the response of platelets to agonists. Results of our studies demonstrate that low doses of alcohol reduces platelet function...
  24. ncbi Polymorphisms in the hANP (human atrial natriuretic peptide) gene, albuminuria, and hypertension
    M Nannipieri
    Department of Internal Medicine and Metabolism Unit of the CNR Institute of Clinical Physiology, University of Pisa School of Medicine, Pistoia, Italy
    Hypertension 37:1416-22. 2001
    ..hANP gene variants may exert a protective effect against the development and progression of kidney damage in diabetes...
  25. ncbi Increase in serum uric acid is selectively associated with stroke in type 2 diabetes
    Giuseppe Seghieri
    Diabetes Care 25:1095. 2002
  26. ncbi Overweight and metabolic and hormonal parameter disruption are induced in adult male mice by manipulations during lactation period
    Alberto Loizzo
    Department of Drug Research and Evaluation, Istituto Superiore di Sanita, Roma, Italy
    Pediatr Res 59:111-5. 2006
    ....
  27. ncbi Neonatal taurine administration modifies metabolic programming in male mice
    Alberto Loizzo
    Istituto Superiore di Sanita, Roma, Italy
    Early Hum Dev 83:693-6. 2007
    ..Thus, in rodents, neonatally administered taurine produces enduring effects in a way that could be advantageous for the control of glucose homoeostasis...
  28. ncbi Are the available experimental models of type 2 diabetes appropriate for a gender perspective?
    Flavia Franconi
    University of Sassari INBB Osilo Sassari and Gender Pharmacology Section, School of Biomedical Sciences, Department of Pharmacology, University of Sassari, Via Muroni 23a, 07100 Sassari, Italy franconi uniss it
    Pharmacol Res 57:6-18. 2008
    ..In this review we summarize these concepts and literature in the field and propose a reappraisal of the various animal models for a study of T2D that would take into consideration a gender perspective...