Roberto Minutolo

Summary

Affiliation: Second University of Naples
Country: Italy

Publications

  1. ncbi request reprint Changing the timing of antihypertensive therapy to reduce nocturnal blood pressure in CKD: an 8-week uncontrolled trial
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Naples, Italy
    Am J Kidney Dis 50:908-17. 2007
  2. ncbi request reprint Detection and awareness of moderate to advanced CKD by primary care practitioners: a cross-sectional study from Italy
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Naples, Italy
    Am J Kidney Dis 52:444-53. 2008
  3. pmc Resistant hypertension in nondialysis chronic kidney disease
    Silvio Borrelli
    Division of Nephrology, Second University of Naples, 80125 Naples, Italy
    Int J Hypertens 2013:929183. 2013
  4. pmc Antiproteinuric effect of add-on paricalcitol in CKD patients under maximal tolerated inhibition of renin-angiotensin system: a prospective observational study
    Luca De Nicola
    Nephrology Departments at Second University, Napoli, Italia
    BMC Nephrol 13:150. 2012
  5. doi request reprint Hyporesponsiveness to erythropoiesis-stimulating agents and renal survival in non-dialysis CKD patients
    Roberto Minutolo
    Division of Nephrology, Second University of Naples, Naples, Italy
    Nephrol Dial Transplant 27:2880-6. 2012
  6. ncbi request reprint Management of cardiovascular risk factors in advanced type 2 diabetic nephropathy: a comparative analysis in nephrology, diabetology and primary care settings
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Naples, Italy
    J Hypertens 24:1655-61. 2006
  7. doi request reprint Prognostic role of ambulatory blood pressure measurement in patients with nondialysis chronic kidney disease
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Naples, Italy
    Arch Intern Med 171:1090-8. 2011
  8. ncbi request reprint Prevalence and clinical correlates of white coat hypertension in chronic kidney disease
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Via Tiberio 90 I 80125, Naples, Italy
    Nephrol Dial Transplant 22:2217-23. 2007
  9. ncbi request reprint [Blood pressure control in Europe is worse than in the USA]
    Roberto Minutolo
    Cattedra di Nefrologia, Seconda Universita degli Studi, Napoli
    G Ital Nefrol 24:284. 2007
  10. doi request reprint Conversion of darbepoetin to low doses of CERA maintains hemoglobin levels in non-dialysis chronic kidney disease patients
    Roberto Minutolo
    Nephrology Division, Second University of Naples, S M d P Incurabili Hospital ASL NA1, Via Maria Longo 50, Naples, Italy
    Blood Purif 30:186-94. 2010

Detail Information

Publications54

  1. ncbi request reprint Changing the timing of antihypertensive therapy to reduce nocturnal blood pressure in CKD: an 8-week uncontrolled trial
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Naples, Italy
    Am J Kidney Dis 50:908-17. 2007
    ..We examined whether shifting 1 antihypertensive drug from morning to evening restores the circadian rhythm of blood pressure in nondipper patients with CKD...
  2. ncbi request reprint Detection and awareness of moderate to advanced CKD by primary care practitioners: a cross-sectional study from Italy
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Naples, Italy
    Am J Kidney Dis 52:444-53. 2008
    ..Although general practitioners (GPs) represent the first line for identification of these high-risk patients, their diagnostic approach to CKD is ill defined...
  3. pmc Resistant hypertension in nondialysis chronic kidney disease
    Silvio Borrelli
    Division of Nephrology, Second University of Naples, 80125 Naples, Italy
    Int J Hypertens 2013:929183. 2013
    ..Recently we have demonstrated that "true" RH represents an independent risk factor for renal and cardiovascular outcomes in CKD patients...
  4. pmc Antiproteinuric effect of add-on paricalcitol in CKD patients under maximal tolerated inhibition of renin-angiotensin system: a prospective observational study
    Luca De Nicola
    Nephrology Departments at Second University, Napoli, Italia
    BMC Nephrol 13:150. 2012
    ..5 g/24 h persisting despite anti-RAS therapy titrated to minimize proteinuria in the absence of adverse effects...
  5. doi request reprint Hyporesponsiveness to erythropoiesis-stimulating agents and renal survival in non-dialysis CKD patients
    Roberto Minutolo
    Division of Nephrology, Second University of Naples, Naples, Italy
    Nephrol Dial Transplant 27:2880-6. 2012
    ..Lower responsiveness to erythropoiesis-stimulating agents (ESA-R) predicts cardiovascular (CV) events. Whether ESA-R also affects the risk of end-stage renal disease (ESRD) is unknown...
  6. ncbi request reprint Management of cardiovascular risk factors in advanced type 2 diabetic nephropathy: a comparative analysis in nephrology, diabetology and primary care settings
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Naples, Italy
    J Hypertens 24:1655-61. 2006
    ..To compare the management of cardiovascular risk factors in patients with type 2 DN and an estimated glomerular filtration rate (GFR) of 15-60 ml/min per 1.73 m2 followed in nephrology, diabetology and primary care...
  7. doi request reprint Prognostic role of ambulatory blood pressure measurement in patients with nondialysis chronic kidney disease
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Naples, Italy
    Arch Intern Med 171:1090-8. 2011
    ....
  8. ncbi request reprint Prevalence and clinical correlates of white coat hypertension in chronic kidney disease
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Via Tiberio 90 I 80125, Naples, Italy
    Nephrol Dial Transplant 22:2217-23. 2007
    ..The role of white coat hypertension (WCH) in the poor control of blood pressure (BP) in chronic kidney disease (CKD) is ill defined...
  9. ncbi request reprint [Blood pressure control in Europe is worse than in the USA]
    Roberto Minutolo
    Cattedra di Nefrologia, Seconda Universita degli Studi, Napoli
    G Ital Nefrol 24:284. 2007
  10. doi request reprint Conversion of darbepoetin to low doses of CERA maintains hemoglobin levels in non-dialysis chronic kidney disease patients
    Roberto Minutolo
    Nephrology Division, Second University of Naples, S M d P Incurabili Hospital ASL NA1, Via Maria Longo 50, Naples, Italy
    Blood Purif 30:186-94. 2010
    ..Finding the lowest effective dose of erythropoietin-stimulating agents is critical in the management of renal anemia. We evaluated the efficacy of converting darbepoetin to CERA at doses lower than those usually recommended...
  11. ncbi request reprint Effects of age on hypertensive status in patients with chronic kidney disease
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Italy
    J Hypertens 25:2325-33. 2007
    ..To evaluate effect of age on hypertensive status in chronic kidney disease (CKD)...
  12. ncbi request reprint [Outpatient blood pressure monitoring in patients with predialysis chronic renal failure]
    Roberto Minutolo
    Cattedra di Nefrologia, Seconda Universita degli Studi, Napoli Italy
    G Ital Nefrol 25:155. 2008
  13. doi request reprint Effect of furosemide on left ventricular mass in non-dialysis chronic kidney disease patients: a randomized controlled trial
    Pasquale Zamboli
    Division of Nephrology, Second University of Naples, Naples, Italy
    Nephrol Dial Transplant 26:1575-83. 2011
    ..In chronic kidney disease (CKD), loop diuretics correct volume-dependent hypertension, but their effect on left ventricular mass index (LVMI) is unknown...
  14. ncbi request reprint Intra- and post-dialytic changes of haemoglobin concentrations in non-anaemic haemodialysis patients
    Roberto Minutolo
    Chair of Nephrology, School of Medicine, Second University of Naples, via Tiberio 90, 80125 Naples, Italy
    Nephrol Dial Transplant 18:2606-12. 2003
    ..No study, however, has assessed the effects of dialytic session on haemoglobin (Hb) levels in these patients...
  15. ncbi request reprint Management of hypertension in patients with CKD: differences between primary and tertiary care settings
    Roberto Minutolo
    Department of Nephrology, Second University of Naples, Naples, Italy
    Am J Kidney Dis 46:18-25. 2005
    ..We compared hypertension management in patients with CKD followed up in PC and nephrology tertiary care (TC)...
  16. pmc Epoetin therapy and hemoglobin level variability in nondialysis patients with chronic kidney disease
    Roberto Minutolo
    Nephrology Division, Second University of Naples Santa Maria del Popolo degli Incurabili Hospital Azienda SanitariaLocale, Solofra, Italy
    Clin J Am Soc Nephrol 4:552-9. 2009
    ..Intrapatient variability of hemoglobin (Hb) is a newly proposed determinant of adverse outcome in chronic kidney disease (CKD). We evaluated whether intensity of epoetin therapy affects Hb variability and renal survival in nondialysis CKD...
  17. ncbi request reprint The effect of increasing age on the prognosis of non-dialysis patients with chronic kidney disease receiving stable nephrology care
    Luca De Nicola
    Nephrology Division, Second University of Napoli, Napoli, Italy
    Kidney Int 82:482-8. 2012
    ..Proteinuria increases ESRD risk, while the predictive role of other modifiable risk factors was unchanged compared with younger patients...
  18. doi request reprint Hypertension management in chronic kidney disease: translating guidelines into daily practice
    Luca De Nicola
    Division of Nephrology, Second University of Naples, Naples, Italy
    J Nephrol 24:733-41. 2011
    ..This historical cohort analysis evaluated the relationship between 1-year nephrology management and BP control in 275 incident CKD patients in an academic renal clinic...
  19. doi request reprint High cardiovascular risk in patients with Type 2 diabetic nephropathy: the predictive role of albuminuria and glomerular filtration rate. The NID-2 Prospective Cohort Study
    Ferdinando C Sasso
    Department of Internal and Experimental Medicine, Second University of Naples, Naples, Italy
    Nephrol Dial Transplant 27:2269-74. 2012
    ..In this high-risk population, cardiovascular (CV) outcome has never been evaluated...
  20. doi request reprint Prevalence and prognostic role of resistant hypertension in chronic kidney disease patients
    Luca De Nicola
    Department of Nephrology, Second University of Naples, Naples, Italy
    J Am Coll Cardiol 61:2461-7. 2013
    ..This study sought to evaluate in chronic kidney disease (CKD) prevalence and prognosis of true resistant hypertension (RH) (i.e., confirmed by ambulatory blood pressure [ABP] monitoring)...
  21. pmc Prognosis of CKD patients receiving outpatient nephrology care in Italy
    Luca De Nicola
    Nephrology Division, University of Naples, Naples, Italy
    Clin J Am Soc Nephrol 6:2421-8. 2011
    ..Cumulative incidence of ESRD or death before ESRD were estimated using the competing-risk approach...
  22. doi request reprint Prevalence and prognosis of mild anemia in non-dialysis chronic kidney disease: a prospective cohort study in outpatient renal clinics
    Luca De Nicola
    Nephrology Division and Chair of Biostatistics, Second University of Naples, Naples, Italy
    Am J Nephrol 32:533-40. 2010
    ..we evaluated prevalence and prognosis of mild anemia, defined as Hb (g/dl) 11-13.5 in males and 11-12 in females, in a prospective cohort of stage 3-5 chronic kidney disease (CKD) patients...
  23. ncbi request reprint Stability of target hemoglobin levels during the first year of epoetin treatment in patients with chronic kidney disease
    Luca De Nicola
    Nephrology Division, Second University of Naples Santa Maria del Popolo degli Incurabili Hospital Azienda Sanitaria Locale Napoli 1, Naples, Italy
    Clin J Am Soc Nephrol 2:938-46. 2007
    ..We evaluated extent and correlates of time in target, that is, the time spent with hemoglobin > or = 11 g/dl during the first year of epoetin and its association with renal survival...
  24. ncbi request reprint Antiproteinuric response to dual blockade of the renin-angiotensin system in primary glomerulonephritis: meta-analysis and metaregression
    Fausta Catapano
    Nephrology Division at Second University of Naples S M d P Incurabili Hospital ASL Na1, Naples, Italy
    Am J Kidney Dis 52:475-85. 2008
    ....
  25. ncbi request reprint Supplemented very low protein diet ameliorates responsiveness to erythropoietin in chronic renal failure
    Biagio R Di Iorio
    Department of Nephrology School of Medicine, Second University of Naples, Naples, Italy
    Kidney Int 64:1822-8. 2003
    ..The aim of this study was to evaluate the relationship between uremic state and erythropoiesis in patients with predialytic chronic renal failure (CRF)...
  26. ncbi request reprint Cardiovascular risk factors and disease management in type 2 diabetic patients with diabetic nephropathy
    Ferdinando C Sasso
    Department of Clinical and Experimental Medicine Magrassi Lanzara, Unit of Internal Medicine, Second University of Naples, Via F Petrarca 64, I 80122 Naples, Italy
    Diabetes Care 29:498-503. 2006
    ....
  27. ncbi request reprint Effects of efficiency and length of acetate-free biofiltration session on postdialysis solute rebound
    Paolo Giannattasio
    Nephrology and Dialysis Unit, School of Medicine, Second University of Naples, Country Hospital in Solofra, Naples, Italy
    Am J Kidney Dis 47:1045-54. 2006
    ..We assessed the independent effects of efficiency and length of dialytic session on PDR of urea, phosphate, and potassium...
  28. ncbi request reprint Maximal suppression of renin-angiotensin system in nonproliferative glomerulonephritis
    Carmela Iodice
    Department of Nephrology, School of Medicine, Second University of Naples, Naples, Italy
    Kidney Int 63:2214-21. 2003
    ....
  29. doi request reprint Burden of resistant hypertension in hypertensive patients with non-dialysis chronic kidney disease
    Luca De Nicola
    Division of Nephrology, Second University of Naples, Naples, Italy
    Kidney Blood Press Res 34:58-67. 2011
    ..We evaluated frequency, correlates and prognosis of RH in 300 consecutive incident hypertensive CKD patients in an academic renal clinic...
  30. ncbi request reprint Epidemiology of chronic kidney disease in Italy
    Pasquale Zamboli
    Department of Nephrology, Second University of Naples, Italy
    J Nephrol 23:S16-22. 2010
    ..In this article, we review in detail the prevalence data obtained by the Gubbio study and the Italian Society of Nephrology - Health Search study, and describe the emerging problem of CKD definition in the elderly...
  31. ncbi request reprint Achievement of target blood pressure levels in chronic kidney disease: a salty question?
    Luca De Nicola
    Division of Nephrology, Second University of Naples, Naples, Italy
    Am J Kidney Dis 43:782-95. 2004
    ..Conversely, the major detrimental effect, that is, excessive hypovolemia, can be prevented if daily body weight loss is limited to 0.3 to 0.5 kg during the initial period of treatment...
  32. ncbi request reprint Italian audit on therapy of hypertension in chronic kidney disease: the TABLE-CKD study
    Luca De Nicola
    Division of Nephrology, Second University of Naples, Naples, Italy
    Semin Nephrol 25:425-30. 2005
    ....
  33. ncbi request reprint [Amino acid loss during dialysis treatment]
    Silvio Borrelli
    Cattedra di Nefrologia, Seconda Universita di Napoli, Napoli, Italy
    G Ital Nefrol 28:26-31. 2011
    ..Further studies are necessary to clarify the role of alterations of AA metabolism in the pathogenesis of malnutrition and the potential beneficial effects of BCAA supplementation or alternative treatments in malnourished patients...
  34. doi request reprint Effect of a low- versus moderate-protein diet on progression of CKD: follow-up of a randomized controlled trial
    Bruno Cianciaruso
    Department of Nephrology, University Federico II of Naples, Italy
    Am J Kidney Dis 54:1052-61. 2009
    ..Whether low-protein-diet (LPD) as opposed to moderate-protein-diet (MPD) regimens improve the long-term survival of patients with chronic kidney disease (CKD) or induce protein-caloric malnutrition is unknown...
  35. ncbi request reprint [Limitations of blood pressure target in non-dialysis chronic kidney disease: a question of method?]
    Silvio Borrelli
    Cattedra di Nefrologia, Seconda Universita di Napoli, Italy
    G Ital Nefrol 29:418-24. 2012
    ....
  36. ncbi request reprint [Epidemiology and prognosis of chronic kidney disease in Italy]
    Carlo Garofalo
    Cattedra di Nefrologia, Seconda Universita di Napoli, Napoli Italy
    G Ital Nefrol 29:S3-11. 2012
    ....
  37. doi request reprint Anaemia management in non-dialysis chronic kidney disease: flexibility of target to target stability?
    Luca De Nicola
    Nephrology Division, Second University of Naples, Naples, Italy
    Nephron Clin Pract 114:c236-41. 2010
    ..This minireview summarizes the results and limits of these studies and discusses the potential implications for clinical practice...
  38. ncbi request reprint [Role of paracalcitol in the management of non-dialysis CKD: state of art and... Unmet needs]
    Sara Mascia
    Seconda Universita degli Studi di Napoli, Cattedra di Nefrologia, Napoli Italy
    G Ital Nefrol 27:616-28. 2010
    ....
  39. ncbi request reprint Sodium/Glucose cotransporter 2 inhibitors and prevention of diabetic nephropathy: targeting the renal tubule in diabetes
    Luca De Nicola
    Nephrology Division, Second University of Naples Med School, Naples, Italy Electronic address
    Am J Kidney Dis 64:16-24. 2014
    ..We review the evidence supporting this working hypothesis by integrating the experimental findings with the available clinical data. ..
  40. ncbi request reprint Postdialytic rebound of serum phosphorus: pathogenetic and clinical insights
    Roberto Minutolo
    Division of Nephrology, School of Medicine, Second University of Naples, Via S Antonio a Capodimonte 46, P co Villa Teresa lotto 30, 80131 Naples, Italy
    J Am Soc Nephrol 13:1046-54. 2002
    ..Enhancement of convective removal acutely amplifies the entity of the phenomenon but allows a better control of Ca-P homeostasis in the medium term...
  41. doi request reprint Interaction between phosphorus and parathyroid hormone in non-dialysis CKD patients under nephrology care
    Luca De Nicola
    Division of Nephrology, Med School, Second University of Naples, via S A Capodimonte 46, 80131, Naples, Italy
    J Nephrol 27:57-63. 2014
    ..We evaluated phosphate, calcium and PTH levels during the first year of nephrology care and the prognostic role of month-12 levels in non-dialysis patients referred prior to availability of the novel P binders...
  42. doi request reprint Conversion from epoetin and darbepoetin to C.E.R.A. in non-dialysis CKD patients: a multicenter Italian prospective study in nephrology practice
    Roberto Minutolo
    Division of Nephrology at Second University of Naples S M d P Incurabili Hospital ASL NA1, Naples, Italy
    Blood Purif 36:69-77. 2013
    ..In non-dialysis patients (ND-CKD), C.E.R.A. has been extensively investigated in ESA-naïve subjects but no data are available on its efficacy after switch from other ESA...
  43. ncbi request reprint Clinical policies on the management of chronic kidney disease patients in Italy
    Francesco Locatelli
    Department of Nephrology, Ospedale A Manzoni, Lecco 23900, Italy
    Nephrol Dial Transplant 23:621-6. 2008
    ..The Italian Society of Nephrology (SIN) decided to undertake a multicentre study to obtain a clear picture of clinical policies on chronic kidney disease (CKD) in Italy...
  44. ncbi request reprint [Epidemiology of chronic kidney disease in Italy: current state and contribution of the CARHES study]
    Luca De Nicola
    Societa Italiana di Nefrologia, Roma, Italy
    G Ital Nefrol 28:401-7. 2011
    ..The final results will allow to estimate the level of CKD in Italy and hopefully increase the awareness of this high-risk chronic disease among Italian physicians and health authorities...
  45. doi request reprint Responsiveness to erythropoiesis-stimulating agents in chronic kidney disease: does geography matter?
    Luca De Nicola
    Nephrology Division, Second University of Naples, School of Medicine, Piazza Miraglia, 80131, Naples, Italy
    Drugs 74:159-68. 2014
    ..In this article we provide a reappraisal of current recommendations on anemia management in non-dialysis CKD in light of the geographical differences in individual responsiveness to ESA. ..
  46. ncbi request reprint Changes of serum albumin and C-reactive protein are related to changes of interleukin-6 release by peripheral blood mononuclear cells in hemodialysis patients treated with different membranes
    Bruno Memoli
    Department of Nephrology, University Federico II of Naples, Naples, Italy
    Am J Kidney Dis 39:266-73. 2002
    ....
  47. ncbi request reprint Management of hypertension in chronic kidney disease
    Pasquale Zamboli
    Curr Hypertens Rep 8:497-501. 2006
    ..However, the control rates of blood pressure are usually inadequate with antihypertensive therapy including only these drugs; therefore, addition of other classes of antihypertensive drugs is often required...
  48. ncbi request reprint Influence of the cyclic variation of hydration status on hemoglobin levels in hemodialysis patients
    Vincenzo Bellizzi
    Nephrology Dialysis Unit, Country Hospitals in Lauria, Polla, Ariano Irpino, Italy
    Am J Kidney Dis 40:549-55. 2002
    ..Maintenance hemodialysis (HD) patients were studied to assess the effect on hemoglobin (Hb) concentration induced by the cyclic variation in hydration status...
  49. ncbi request reprint Daily nutrient intake represents a modifiable determinant of nutritional status in chronic haemodialysis patients
    Vincenzo Bellizzi
    Nephrology and Dialysis, Country Hospital in Polla SA, Ariano Irpino AV and Solofra AV and Second University of Naples, Italy
    Nephrol Dial Transplant 18:1874-81. 2003
    ..This study aimed to evaluate the isolated, long-term effect of daily nutrient intake on nutritional status in haemodialysis patients...
  50. ncbi request reprint Supplemented very low-protein diet in advanced CRF: is it money saving?
    Biagio R Di Iorio
    Kidney Int 65:742. 2004
  51. ncbi request reprint Early detection of progressive renal dysfunction in patients with coronary artery disease
    Giorgio Fuiano
    Departments of Nephrology, and Cardiology, University Magna Graecia of Catanzaro, Italy
    Kidney Int 68:2773-80. 2005
    ..This study was aimed at evaluating early abnormalities and outcome of renal function in CAD patients...
  52. ncbi request reprint Is the type of hemodialysis important to control serum phosphate?
    Luca De Nicola
    Blood Purif 24:299-300. 2006
  53. ncbi request reprint Early changes in bioelectrical estimates of body composition in chronic kidney disease
    Vincenzo Bellizzi
    Nephrology and Dialysis Unit, A Landolfi Hospital, Via Melito, Solofra, 83029 Italy
    J Am Soc Nephrol 17:1481-7. 2006
    ..Therefore, BIA represents an attractive clinical tool to detect impairment of body composition from the early stages of CKD...
  54. ncbi request reprint Efficacy of erythropoietin on dialysis in patients with beta thalassemia minor
    Biagio Di Iorio
    Solofra County Hospital, Solofra, Italy
    Blood Purif 22:453-60. 2004
    ....