Luca De Nicola

..We evaluated extent and correlates of time in target, that is, the time spent with hemoglobin > or = 11 g/dl during the first year of epoetin and its association with renal survival...

..This historical cohort analysis evaluated the relationship between 1-year nephrology management and BP control in 275 incident CKD patients in an academic renal clinic...

..5 g/24 h persisting despite anti-RAS therapy titrated to minimize proteinuria in the absence of adverse effects...

..Proteinuria increases ESRD risk, while the predictive role of other modifiable risk factors was unchanged compared with younger patients...

..This minireview summarizes the results and limits of these studies and discusses the potential implications for clinical practice...

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..Conversely, the major detrimental effect, that is, excessive hypovolemia, can be prevented if daily body weight loss is limited to 0.3 to 0.5 kg during the initial period of treatment...

..We evaluated frequency, correlates and prognosis of RH in 300 consecutive incident hypertensive CKD patients in an academic renal clinic...

..The final results will allow to estimate the level of CKD in Italy and hopefully increase the awareness of this high-risk chronic disease among Italian physicians and health authorities...

..Cumulative incidence of ESRD or death before ESRD were estimated using the competing-risk approach...

..The risk of not achieving therapeutic targets is higher in patients with diabetes, CV disease and more advanced CKD...

..To compare the management of cardiovascular risk factors in patients with type 2 DN and an estimated glomerular filtration rate (GFR) of 15-60 ml/min per 1.73 m2 followed in nephrology, diabetology and primary care...

..Intrapatient variability of hemoglobin (Hb) is a newly proposed determinant of adverse outcome in chronic kidney disease (CKD). We evaluated whether intensity of epoetin therapy affects Hb variability and renal survival in nondialysis CKD...

..We examined whether shifting 1 antihypertensive drug from morning to evening restores the circadian rhythm of blood pressure in nondipper patients with CKD...

..We compared hypertension management in patients with CKD followed up in PC and nephrology tertiary care (TC)...

..The role of white coat hypertension (WCH) in the poor control of blood pressure (BP) in chronic kidney disease (CKD) is ill defined...

..To evaluate effect of age on hypertensive status in chronic kidney disease (CKD)...

..In this high-risk population, cardiovascular (CV) outcome has never been evaluated...

..we evaluated prevalence and prognosis of mild anemia, defined as Hb (g/dl) 11-13.5 in males and 11-12 in females, in a prospective cohort of stage 3-5 chronic kidney disease (CKD) patients...

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..Although general practitioners (GPs) represent the first line for identification of these high-risk patients, their diagnostic approach to CKD is ill defined...

..CONCLUSION: The rate of removal of phosphate and urea is a critical determinant of their PDR; conversely, potassium is not influenced by removal rate, likely because of its marked cell compartmentalization...

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..Finding the lowest effective dose of erythropoietin-stimulating agents is critical in the management of renal anemia. We evaluated the efficacy of converting darbepoetin to CERA at doses lower than those usually recommended...

..In this article, we review in detail the prevalence data obtained by the Gubbio study and the Italian Society of Nephrology - Health Search study, and describe the emerging problem of CKD definition in the elderly...

..3 g/kg body weight/day induces a reduction of about 35% of the EPO dose required to maintain the target hemoglobin levels. This effect appears dependent on the correction of a moderate secondary hyperparathyroidism...

..In chronic kidney disease (CKD), loop diuretics correct volume-dependent hypertension, but their effect on left ventricular mass index (LVMI) is unknown...

..Lower responsiveness to erythropoiesis-stimulating agents (ESA-R) predicts cardiovascular (CV) events. Whether ESA-R also affects the risk of end-stage renal disease (ESRD) is unknown...

..No study, however, has assessed the effects of dialytic session on haemoglobin (Hb) levels in these patients...

..The enhancement of RAS suppression up to the maximal degree does not improve the antiproteinuric response and is coupled with a decrement of hemoglobin levels...

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..Enhancement of convective removal acutely amplifies the entity of the phenomenon but allows a better control of Ca-P homeostasis in the medium term...

..Further studies are necessary to clarify the role of alterations of AA metabolism in the pathogenesis of malnutrition and the potential beneficial effects of BCAA supplementation or alternative treatments in malnourished patients...

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..However, the control rates of blood pressure are usually inadequate with antihypertensive therapy including only these drugs; therefore, addition of other classes of antihypertensive drugs is often required...

..The Italian Society of Nephrology (SIN) decided to undertake a multicentre study to obtain a clear picture of clinical policies on chronic kidney disease (CKD) in Italy...

..This study aimed to evaluate the isolated, long-term effect of daily nutrient intake on nutritional status in haemodialysis patients...

..Therefore, BIA represents an attractive clinical tool to detect impairment of body composition from the early stages of CKD...

..This study was aimed at evaluating early abnormalities and outcome of renal function in CAD patients...

..This therapeutic approach permits a complete remission of concentric LV hypertrophy without any adverse effects on the vascular system...