F Scolari

Summary

Country: Italy

Publications

  1. doi request reprint Atheroembolic renal disease
    Francesco Scolari
    Faculty of Medicine, University of Brescia, Brescia, Italy
    Lancet 375:1650-60. 2010
  2. pmc The IgA nephropathy Biobank. An important starting point for the genetic dissection of a complex trait
    Francesco P Schena
    Renal Unit, University of Bari, Italy
    BMC Nephrol 6:14. 2005
  3. ncbi request reprint [Atheroembolic renal disease: a diagnostic challenge]
    Francesco Scolari
    Divisione di Nefrologia, Presidio di Montichiari dell Azienda Ospedaliera Spedali Riuniti di Brescia, Montichiari
    Recenti Prog Med 99:377-88. 2008
  4. ncbi request reprint The challenge of diagnosing atheroembolic renal disease: clinical features and prognostic factors
    Francesco Scolari
    Division of Nephrology, University and Spedali Civili, Brescia, Italy
    Circulation 116:298-304. 2007
  5. ncbi request reprint Familial clustering of IgA nephropathy: further evidence in an Italian population
    F Scolari
    Division of Nephrology, Spedali Civili, Brescia, Italy
    Am J Kidney Dis 33:857-65. 1999
  6. ncbi request reprint Inherited forms of IgA nephropathy
    Francesco Scolari
    Division of Nephrology, Spedali Civili, Ple Ospedale Civili 1, 25125 Brescia, Italy
    J Nephrol 16:317-20. 2003
  7. ncbi request reprint Predictors of renal and patient outcomes in atheroembolic renal disease: a prospective study
    Francesco Scolari
    Division and Chair of Nephrology, Spedali Civili and University, Brescia, Italy
    J Am Soc Nephrol 14:1584-90. 2003
  8. ncbi request reprint Cholesterol crystal embolic disease in renal allografts
    Francesco Scolari
    Spedali Civili and University, Brescia, Italy
    J Nephrol 16:139-43. 2003
  9. ncbi request reprint Cholesterol crystal embolism: A recognizable cause of renal disease
    F Scolari
    Division and Chair of Nephrology and Department and Chair of Pathology, Spedali Civili and University, Brescia, Italy
    Am J Kidney Dis 36:1089-109. 2000
  10. ncbi request reprint Renal apolipoprotein A-I amyloidosis: a rare and usually ignored cause of hereditary tubulointerstitial nephritis
    Gina Gregorini
    Division of Nephrology, Spedali Civili, Brescia, Italy
    J Am Soc Nephrol 16:3680-6. 2005

Collaborators

Detail Information

Publications37

  1. doi request reprint Atheroembolic renal disease
    Francesco Scolari
    Faculty of Medicine, University of Brescia, Brescia, Italy
    Lancet 375:1650-60. 2010
    ..Statins, which stabilise atherosclerotic plaques, should be offered to all patients. Steroids might have a role in acute or subacute progressive forms with systemic inflammation...
  2. pmc The IgA nephropathy Biobank. An important starting point for the genetic dissection of a complex trait
    Francesco P Schena
    Renal Unit, University of Bari, Italy
    BMC Nephrol 6:14. 2005
    ..The organization of a multi-centre Biobank for the collection of biological samples and clinical data from IgAN patients and relatives is an important starting point for the identification of the disease susceptibility genes...
  3. ncbi request reprint [Atheroembolic renal disease: a diagnostic challenge]
    Francesco Scolari
    Divisione di Nefrologia, Presidio di Montichiari dell Azienda Ospedaliera Spedali Riuniti di Brescia, Montichiari
    Recenti Prog Med 99:377-88. 2008
    ..Atheroembolic renal disease is an important yet underdiagnosed component of the spectrum of kidney diseases associated with atherosclerosis and remains an unexplored field of nephrology research...
  4. ncbi request reprint The challenge of diagnosing atheroembolic renal disease: clinical features and prognostic factors
    Francesco Scolari
    Division of Nephrology, University and Spedali Civili, Brescia, Italy
    Circulation 116:298-304. 2007
    ..Embolization may occur spontaneously or after angiographic/surgical procedures. We sought to determine clinical features and prognostic factors of AERD...
  5. ncbi request reprint Familial clustering of IgA nephropathy: further evidence in an Italian population
    F Scolari
    Division of Nephrology, Spedali Civili, Brescia, Italy
    Am J Kidney Dis 33:857-65. 1999
    ..In addition, this subgroup of patients with IgA nephropathy offers an ideal opportunity to elucidate the molecular genetics of this disease...
  6. ncbi request reprint Inherited forms of IgA nephropathy
    Francesco Scolari
    Division of Nephrology, Spedali Civili, Ple Ospedale Civili 1, 25125 Brescia, Italy
    J Nephrol 16:317-20. 2003
    ..Future study will be focused on the identification of the gene underlying IGAN-1. This will enable us to understand the molecular pathogenetic basis of IgAN...
  7. ncbi request reprint Predictors of renal and patient outcomes in atheroembolic renal disease: a prospective study
    Francesco Scolari
    Division and Chair of Nephrology, Spedali Civili and University, Brescia, Italy
    J Am Soc Nephrol 14:1584-90. 2003
    ..The protective effect of statins on the development of ESRD should be evaluated in a prospective study...
  8. ncbi request reprint Cholesterol crystal embolic disease in renal allografts
    Francesco Scolari
    Spedali Civili and University, Brescia, Italy
    J Nephrol 16:139-43. 2003
    ..Particular care must be taken at the time of organ procurement and during the evaluation of organ donors, in order to reduce the risk of embolization...
  9. ncbi request reprint Cholesterol crystal embolism: A recognizable cause of renal disease
    F Scolari
    Division and Chair of Nephrology and Department and Chair of Pathology, Spedali Civili and University, Brescia, Italy
    Am J Kidney Dis 36:1089-109. 2000
    ..Finally, recent data suggest that an aggressive therapeutic approach with patient-tailored supportive measures may be associated with a favorable clinical outcome...
  10. ncbi request reprint Renal apolipoprotein A-I amyloidosis: a rare and usually ignored cause of hereditary tubulointerstitial nephritis
    Gina Gregorini
    Division of Nephrology, Spedali Civili, Brescia, Italy
    J Am Soc Nephrol 16:3680-6. 2005
    ..Patients who present with familial tubulointerstitial nephritis associated with liver disease require a high index of suspicion for apolipoprotein A-I amyloidosis...
  11. ncbi request reprint Familial aggregation of primary glomerulonephritis in an Italian population isolate: Valtrompia study
    C Izzi
    Division of Nephrology, Brescia University, Italy
    Kidney Int 69:1033-40. 2006
    ..Further molecular study of our families will offer the possibility to shed light on the genetic background underlying these glomerular disorders...
  12. ncbi request reprint Direct effect of the correction of acidosis on plasma parathyroid hormone concentrations, calcium and phosphate in hemodialysis patients: a prospective study
    E Movilli
    Division of Nephrology Spedali Civili and Chair of Nephrology, University of Brescia, P. le Ospedale Civile, I-25123 Brescia, Italy
    Nephron 87:257-62. 2001
    ..CONCLUSIONS: Our study demonstrates that the correction of metabolic acidosis in chronic HD patients reduces iPTH concentrations in HD patients with secondary hyperparathyroidism possibly by a direct effect on iPTH secretion...
  13. ncbi request reprint Clinical and morphological features of kidney involvement in primary Sjögren's syndrome
    N Bossini
    Division of Nephrology, , Brescia, Italy
    Nephrol Dial Transplant 16:2328-36. 2001
    ..CONCLUSIONS: Kidney involvement is a frequent extraglandular manifestation of primary Sjögren's syndrome. It is rarely overt and may precede the onset of subjective sicca syndrome...
  14. ncbi request reprint [Choosing the right treatment approach in focal and segmental glomerular sclerosis with chronic renal failure]
    F Valerio
    Cattedra e Divisione di Nefrologia, Università e Spedali Civili, Brescia, Italy
    G Ital Nefrol 25:S88-S98. 2008
    ..in patients with a glomerular filtration rate of less than 40 mL/min, the use of calcineurin inhibitors should be avoided...
  15. ncbi request reprint Towards the identification of (a) gene(s) for autosomal dominant medullary cystic kidney disease
    Francesco Scolari
    Division and Chair of Nephrology, Spedali Civili, Brescia, Italy
    J Nephrol 16:321-8. 2003
    ..Identification and characterization of the MCKD and FJHN genes will help to clarify the pathogenesis and classification of hereditary tubulo-interstitial nephritides...
  16. pmc Identification of a new locus for medullary cystic disease, on chromosome 16p12
    F Scolari
    Division and Chair of Nephrology, Spedali Civili and University of Brescia, Brescia, Italy
    Am J Hum Genet 64:1655-60. 1999
    ..Marker D16S3036 shows a maximum two-point LOD score of 3.68, and the defined critical region spans 10.5 cM, between D16S500 and SCNN1B1-2. Candidate genes included in the critical region are discussed...
  17. ncbi request reprint IgA nephropathy: the presence of familial disease does not confer an increased risk for progression
    Claudia Izzi
    Divisione di Nefrologia, Università e Spedali Civili, Brescia, Italy
    Am J Kidney Dis 47:761-9. 2006
    ..Familial and sporadic cases are recognized, and a locus associated with the familial form of the disease was mapped to chromosome 6. Recent data suggest the familial IgA nephropathy form may have a poorer outcome than the sporadic form...
  18. ncbi request reprint Predialysis versus postdialysis hematocrit evaluation during erythropoietin therapy
    Ezio Movilli
    Division of Nephrology, School of Medicine, Spedali Civili and University of Brescia, Brescia, Italy
    Am J Kidney Dis 39:850-3. 2002
    ..For these reasons, predialysis samples for monitoring the target Hb and Hct levels in patients treated by rHuEPO should be considered with caution...
  19. ncbi request reprint The kind of vascular access influences the baseline inflammatory status and epoetin response in chronic hemodialysis patients
    Ezio Movilli
    Chair and Division of Nephrology, Spedali Civili and University of Brescia, University of Brescia, Brescia, Italy
    Blood Purif 24:387-93. 2006
    ....
  20. ncbi request reprint Uromodulin storage diseases: clinical aspects and mechanisms
    Francesco Scolari
    Divisione di Nefrologia, Spedali Civili, Brescia, Italy
    Am J Kidney Dis 44:987-99. 2004
    ..Intracellular uromodulin trapping within the ER probably has a major role in determining tubulointerstitial fibrosis and renal failure. We propose the definition of uromodulin storage diseases for conditions with proven UMOD mutations...
  21. pmc Genetic heterogeneity in Italian families with IgA nephropathy: suggestive linkage for two novel IgA nephropathy loci
    Luigi Bisceglia
    Medical Genetic Service, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy
    Am J Hum Genet 79:1130-4. 2006
    ..Although we identified new candidate regions, replication studies are required to confirm the genetic contribution to familial IgAN...
  22. ncbi request reprint Defective intracellular trafficking of uromodulin mutant isoforms
    Ilenia Bernascone
    Dulbecco Telethon Institute, DIBIT, San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy
    Traffic 7:1567-79. 2006
    ....
  23. ncbi request reprint Broadening the spectrum of diseases related to podocin mutations
    Gianluca Caridi
    Laboratory on Pathophysiology of Uremia, Istituto G Gaslini, 16148 Genoa, Italy
    J Am Soc Nephrol 14:1278-86. 2003
    ..A suggested alternative is the involvement of other gene(s) or factor(s)...
  24. ncbi request reprint Allelism of MCKD, FJHN and GCKD caused by impairment of uromodulin export dynamics
    Luca Rampoldi
    DIBIT San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy
    Hum Mol Genet 12:3369-84. 2003
    ..Consistently, patient urines show a severe reduction of excreted uromodulin. The maturation impairment is consistent with the clinical findings and suggests a pathogenetic mechanism leading to these kidney diseases...
  25. ncbi request reprint Recurrence of focal segmental glomerulosclerosis after renal transplantation in patients with mutations of podocin
    Roberta Bertelli
    Laboratory on Pathophysiology of Uremia, G Gaslini Children s Hospital, Genoa, Italy
    Am J Kidney Dis 41:1314-21. 2003
    ..Familial forms of FSGS do not recur, but the discovery of numerous patients with sporadic FSGS and mutations of podocin (NPHS2, that is actually an inherited disease) who received a renal graft require a re-evaluation of the problem...
  26. pmc Localization of a gene for nonsyndromic renal hypodysplasia to chromosome 1p32-33
    Simone Sanna-Cherchi
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Am J Hum Genet 80:539-49. 2007
    ..These data show that autosomal dominant nonsyndromic renal hypodysplasia and associated urinary tract malformations are genetically heterogeneous and identify a locus for this common cause of human kidney failure...
  27. pmc Genetic approaches to human renal agenesis/hypoplasia and dysplasia
    Simone Sanna-Cherchi
    Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Pediatr Nephrol 22:1675-84. 2007
    ..The goal appears to be feasible with the large multicentric collaborative groups that share the same objectives and resources...
  28. doi request reprint Determination of the oxido-redox status of plasma albumin in hemodialysis patients
    Maurizio Bruschi
    Laboratory on Pathophysiology of Uremia, G Gaslini Children Hospital, Genoa, Italy Renal Child Foundation, Genoa, Italy
    J Chromatogr B Analyt Technol Biomed Life Sci 864:29-37. 2008
    ..LC-ESI-MS/MS was crucial to characterize albumin in conditions of oxidation stress; surrogate techniques can mirror conformational changes induced by oxidation...
  29. ncbi request reprint Active focal segmental glomerulosclerosis is associated with massive oxidation of plasma albumin
    Luca Musante
    Laboratory on Pathophysiology of Uremia, G Gaslini Children Hospital, Largo G Gaslini, 5 16148 Genova, Italy
    J Am Soc Nephrol 18:799-810. 2007
    ..Albumin oxidation seems to be specific for FSGS, suggesting some pathogenetic implications. Free radical involvement in FSGS may lead to specific therapeutic interventions...
  30. ncbi request reprint Rare functional variants of podocin (NPHS2) promoter in patients with nephrotic syndrome
    Roberta Oleggini
    Department of Clinical Medicine, Nephrology and Health Sciences, University of Parma, Italy
    Gene Expr 13:59-66. 2006
    ..USF1 was identified as the transcriptional factor regulating NPHS2 at this site. Even if not sufficient to cause FSGS per se, these variants could represent modifiers for severity and/or progression of the disease...
  31. ncbi request reprint A high calcium-phosphate product is associated with high C-reactive protein concentrations in hemodialysis patients
    Ezio Movilli
    Nephron Clin Pract 101:c161-7. 2005
    ..For this reason we have evaluated in a cross-sectional and in an interventional study the possible correlation between CaxPO4 and CRP and the effect of the correction of a high CaxPO4 on CRP levels...
  32. ncbi request reprint Cyclosporine in patients with steroid-resistant nephrotic syndrome: an open-label, nonrandomized, retrospective study
    Gian Marco Ghiggeri
    Department of Nephrology, G Gaslini Children s Hospital, Genova, Italy
    Clin Ther 26:1411-8. 2004
    ..In the past decade, immunosuppressive drugs such as cyclosporine (CsA) and cyclophosphamide have been introduced for the treatment of SRNS, but data on long-term clinical outcome (over years) are lacking...
  33. ncbi request reprint Liver biopsy discloses a new apolipoprotein A-I hereditary amyloidosis in several unrelated Italian families
    Laura Obici
    Biotechnology Research Laboratories, IRCCS Policlinico San Matteo, Viale Golgi 19, 27100 Pavia, Italy
    Gastroenterology 126:1416-22. 2004
    ....
  34. ncbi request reprint Depletion of clusterin in renal diseases causing nephrotic syndrome
    Gian Marco Ghiggeri
    Laboratory on Pathophysiology of Uremia and Unit of Nephrology, Istituto Giannina Gaslini, Genova, Italy
    Kidney Int 62:2184-94. 2002
    ..In focal segmental glomerulosclerosis (FSGS), it inhibits permeability plasma factor activity and could influence proteinuria. Moreover, with aging, knockout mice for clusterin develop a progressive glomerulopathy with sclerosis...
  35. ncbi request reprint Apolipoprotein E in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis
    Maurizio Bruschi
    Laboratory of Pathophysiology of Uremia and Unit of Nephrology, G Gaslini Children s Hospital, Genoa, Italy
    Kidney Int 63:686-95. 2003
    ..The data in the literature support an implication of apolipoprotein E (apoE) in both hyperlipemia and focal segmental glomerulosclerosis (FSGS), a malignant condition associated with NS...
  36. ncbi request reprint Familial vesicoureteral reflux: testing replication of linkage in seven new multigenerational kindreds
    Simone Sanna-Cherchi
    Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, 630 W 168th Street, P and S 10 432 New York, NY 10032, USA
    J Am Soc Nephrol 16:1781-7. 2005
    ....