Alessandro Sciarra

Summary

Country: Italy

Publications

  1. doi request reprint Intermittent androgen-deprivation therapy in prostate cancer: a critical review focused on phase 3 trials
    Alessandro Sciarra
    Department of Urology, University Sapienza, Rome, Italy Electronic address
    Eur Urol 64:722-30. 2013
  2. doi request reprint Thulium laser supported nephron sparing surgery for renal cell carcinoma
    Alessandro Sciarra
    Department of Urology, University Sapienza, Rome, Italy
    J Urol 190:698-701. 2013
  3. doi request reprint Predictors for response to intermittent androgen deprivation (IAD) in prostate cancer cases with biochemical progression after surgery
    Alessandro Sciarra
    Department of Urology, University Sapienza, Rome, Italy
    Urol Oncol 31:607-14. 2013
  4. doi request reprint Multiparametric magnetic resonance imaging of the prostate can improve the predictive value of the urinary prostate cancer antigen 3 test in patients with elevated prostate-specific antigen levels and a previous negative biopsy
    Alessandro Sciarra
    Department of Radiology, Sapienza University of Rome, Rome, Italy
    BJU Int 110:1661-5. 2012
  5. doi request reprint Determination of the time for maximal response to neoadjuvant hormone therapy for prostate cancer using magnetic resonance with spectroscopy (MRSI) and dynamic contrast enhancement (DCEMR)
    Alessandro Sciarra
    Department of Urology, University Sapienza of Rome, Rome, Italy
    Urol Oncol 30:614-9. 2012
  6. doi request reprint The emerging role of targeted therapy in renal cell carcinoma (RCC): is it time for a neoadjuvant or an adjuvant approach?
    Alessandro Sciarra
    Department of Urology U Bracci, University Sapienza of Rome, Viale Policlinico 155, 00161 Rome, Italy
    Crit Rev Oncol Hematol 81:151-62. 2012
  7. ncbi request reprint Words of wisdom. Re: Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, diagnosis, and therapy. Stillebroer AB, Mulders PFA, Boerman DC, Oyen WJG, Oosterwijk. E Eur Urol. In press. DOI: 10.1016/j.eururo.2010.03.015
    Alessandro Sciarra
    Department of Urology Bracci, University Sapienza of Rome, Italy
    Eur Urol 58:316. 2010
  8. ncbi request reprint Words of wisdom. Re: Retrospective analysis of prostate cancer recurrence potential with tissue metabolomic profiles. Maxeiner A, Adkins CB, Zhang Y, et al. Prostate 2010;70:710-7
    Alessandro Sciarra
    Department of Urology Bracci, University Sapienza of Rome, Italy
    Eur Urol 58:315. 2010
  9. ncbi request reprint Magnetic resonance spectroscopic imaging ((1)H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI): Pattern changes from inflammation to prostate cancer
    Alessandro Sciarra
    Department of Urology, Sapienza University of Rome, Italy
    Cancer Invest 120:424-32. 2010
  10. doi request reprint Value of magnetic resonance spectroscopy imaging and dynamic contrast-enhanced imaging for detecting prostate cancer foci in men with prior negative biopsy
    Alessandro Sciarra
    Department of Urology, University Sapienza, and Department of Urology, University of Rome, Rome, Italy
    Clin Cancer Res 16:1875-83. 2010

Collaborators

Detail Information

Publications65

  1. doi request reprint Intermittent androgen-deprivation therapy in prostate cancer: a critical review focused on phase 3 trials
    Alessandro Sciarra
    Department of Urology, University Sapienza, Rome, Italy Electronic address
    Eur Urol 64:722-30. 2013
    ..Intermittent androgen deprivation (IAD) in prostate cancer (PCa) patients has been proposed to delay development of castration resistance and to reduce the side effects and costs of androgen deprivation therapy (ADT)...
  2. doi request reprint Thulium laser supported nephron sparing surgery for renal cell carcinoma
    Alessandro Sciarra
    Department of Urology, University Sapienza, Rome, Italy
    J Urol 190:698-701. 2013
    ..We analyze the feasibility, advantages and results of the use of a thulium laser in nephron sparing surgery for renal cell carcinoma...
  3. doi request reprint Predictors for response to intermittent androgen deprivation (IAD) in prostate cancer cases with biochemical progression after surgery
    Alessandro Sciarra
    Department of Urology, University Sapienza, Rome, Italy
    Urol Oncol 31:607-14. 2013
    ..To define characteristics of the first cycle of intermittent androgen deprivation (IAD) that would predict for outcomes in a long term follow-up...
  4. doi request reprint Multiparametric magnetic resonance imaging of the prostate can improve the predictive value of the urinary prostate cancer antigen 3 test in patients with elevated prostate-specific antigen levels and a previous negative biopsy
    Alessandro Sciarra
    Department of Radiology, Sapienza University of Rome, Rome, Italy
    BJU Int 110:1661-5. 2012
    ..However, further larger randomized studies on this combination using a new biomarker and a new imaging modality for PC diagnosis are expected...
  5. doi request reprint Determination of the time for maximal response to neoadjuvant hormone therapy for prostate cancer using magnetic resonance with spectroscopy (MRSI) and dynamic contrast enhancement (DCEMR)
    Alessandro Sciarra
    Department of Urology, University Sapienza of Rome, Rome, Italy
    Urol Oncol 30:614-9. 2012
    ..To determine the time-dependent metabolic and angiogenic changes that occur in prostate cancer (CaP) during neoadjuvant hormone therapy (HT), using a combination of MRSI and DCEMR analysis...
  6. doi request reprint The emerging role of targeted therapy in renal cell carcinoma (RCC): is it time for a neoadjuvant or an adjuvant approach?
    Alessandro Sciarra
    Department of Urology U Bracci, University Sapienza of Rome, Viale Policlinico 155, 00161 Rome, Italy
    Crit Rev Oncol Hematol 81:151-62. 2012
    ..We address whether rational and significant clinical data exist on using angiogenic targeted therapies as neoadjuvant or adjuvant options to nephrectomy in non-metastatic RCC...
  7. ncbi request reprint Words of wisdom. Re: Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, diagnosis, and therapy. Stillebroer AB, Mulders PFA, Boerman DC, Oyen WJG, Oosterwijk. E Eur Urol. In press. DOI: 10.1016/j.eururo.2010.03.015
    Alessandro Sciarra
    Department of Urology Bracci, University Sapienza of Rome, Italy
    Eur Urol 58:316. 2010
    ..Similarly, CAIX expression was associated with a significantly higher treatment response rate in patients with metastatic RCC who received sorafenib...
  8. ncbi request reprint Words of wisdom. Re: Retrospective analysis of prostate cancer recurrence potential with tissue metabolomic profiles. Maxeiner A, Adkins CB, Zhang Y, et al. Prostate 2010;70:710-7
    Alessandro Sciarra
    Department of Urology Bracci, University Sapienza of Rome, Italy
    Eur Urol 58:315. 2010
    ..The suggestion is that PCa metabolic profiles studied at RP with MRS may provide available adjunct parameter to predict the risk of progression after surgery...
  9. ncbi request reprint Magnetic resonance spectroscopic imaging ((1)H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI): Pattern changes from inflammation to prostate cancer
    Alessandro Sciarra
    Department of Urology, Sapienza University of Rome, Italy
    Cancer Invest 120:424-32. 2010
    ..CONCLUSION: our results suggest the potential for these MR imaging techniques in the description of inflammatory and proliferative lesions inside the prostate gland...
  10. doi request reprint Value of magnetic resonance spectroscopy imaging and dynamic contrast-enhanced imaging for detecting prostate cancer foci in men with prior negative biopsy
    Alessandro Sciarra
    Department of Urology, University Sapienza, and Department of Urology, University of Rome, Rome, Italy
    Clin Cancer Res 16:1875-83. 2010
    ....
  11. doi request reprint Magnetic resonance spectroscopic imaging (1H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI): pattern changes from inflammation to prostate cancer
    Alessandro Sciarra
    Department of Urology, Sapienza University, Viale Policlinico 155, Rome, Italy
    Cancer Invest 28:424-32. 2010
    ....
  12. ncbi request reprint Update on screening in prostate cancer based on recent clinical trials
    Alessandro Sciarra
    University Sapienza of Rome, Italy
    Rev Recent Clin Trials 6:7-15. 2011
    ..The aim of this article is to review the current screening guidelines and summarise the benefits and harms of PSA testing, analysing two large long awaited randomized multicenter clinical trials of PSA screening reported this year...
  13. ncbi request reprint Comparative effect of finasteride and dutasteride on chromogranin A levels
    Alessandro Sciarra
    Department of Urology, University Sapienza of Rome, Italy
    Anticancer Res 30:4737-42. 2010
    ....
  14. doi request reprint [Neuroendocrine target therapies for prostate cancer]
    Alessandro Sciarra
    Dipartimento di Scienze Ginecologico Ostetriche e Scienze Urologiche, Universita di Roma Sapienza, Roma, Italy
    Urologia 78:137-41. 2011
    ..This combined therapy also sustains the new concept in cancer treatment in which therapies may target not only cancer cells but also its microenvironment, which can yield protection against apoptosis...
  15. doi request reprint [Current diagnostic procedure on neuroendocrine differentiation of prostate cancer]
    Alessandro Sciarra
    Dipartimento di Scienze Ginecologico Ostetriche e Scienze Urologiche, Universita di Roma Sapienza, Roma, Italy
    Urologia 78:132-6. 2011
    ..A more specific system to detect NE cell activity is obtained by analyzing CgA gene expression in prostate tissue by a semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR)...
  16. doi request reprint [Role of neuroendocrine cells in prostate cancer progression]
    Alessandro Sciarra
    Dipartimento di Scienze Ginecologico Ostetriche e Scienze Urologiche, Universita di Roma Sapienza, Roma, Italy
    Urologia 78:126-31. 2011
    ..Currently there are no clinical data available to support an active role of radiotherapy in NE differentiation...
  17. doi request reprint Advances in magnetic resonance imaging: how they are changing the management of prostate cancer
    Alessandro Sciarra
    Department of Urology, Sapienza University of Rome, Rome, Italy
    Eur Urol 59:962-77. 2011
    ..Recently, great interest has been shown in multiparametric MRI, which combines anatomic T2-weighted (T2W) imaging with MR spectroscopic imaging (MRSI), dynamic contrast-enhanced MRI (DCE-MRI), and diffusion-weighted imaging (DWI)...
  18. doi request reprint Neoadjuvant therapy with sorafenib in advanced renal cell carcinoma with vena cava extension submitted to radical nephrectomy
    Franco Di Silverio
    Department of Urology, University of Rome, Rome, Italy
    Urol Int 80:451-3. 2008
    ..0 cm in diameter solid mass in the left kidney but a reduction in thrombus extension, limited to the left renal vein. At histological examination after radical nephrectomy, over 90% of the renal mass was substituted by necrotic tissue...
  19. ncbi request reprint PCA3 urinary test versus 1H-MRSI and DCEMR in the detection of prostate cancer foci in patients with biochemical alterations
    Valeria Panebianco
    Department of Radiological Sciences, Sapienza Rome University Policlinico Umberto I, Rome, Italy
    Anticancer Res 31:1399-405. 2011
    ....
  20. doi request reprint Role of dynamic contrast-enhanced magnetic resonance (MR) imaging and proton MR spectroscopic imaging in the detection of local recurrence after radical prostatectomy for prostate cancer
    Alessandro Sciarra
    Department of Urology, University Sapienza, Rome, Italy
    Eur Urol 54:589-600. 2008
    ....
  21. ncbi request reprint Complete response to the combination therapy with androgen blockade and somatostatin analogue in a patient with advanced prostate cancer: magnetic resonance imaging with 1H-spectroscopy
    Alessandro Sciarra
    Department of Urology, University La Sapienza, Rome, Italy
    Eur Urol 53:652-5. 2008
    ..Serum prostate-specific antigen and chromogranin A levels steadily decreased over a 12-mo follow-up period, at which time the patient is alive without disease progression and with a complete objective and symptomatic response...
  22. ncbi request reprint Clinical understaging in patients with prostate adenocarcinoma submitted to radical prostatectomy: predictive value of serum chromogranin A
    Alessandro Sciarra
    University La Sapienza, Department of Urology, Rome, Italy
    Prostate 58:421-8. 2004
    ....
  23. ncbi request reprint Effect of nonsteroidal antiandrogen monotherapy versus castration therapy on neuroendocrine differentiation in prostate carcinoma
    Alessandro Sciarra
    Department of Urology U Bracci, University La Sapienza, Rome, Italy
    Urology 63:523-7. 2004
    ..It has been hypothesized that continuous androgen suppression for the treatment of prostate cancer results in hyperactivation of neuroendocrine cells and an increase in CgA levels...
  24. doi request reprint Distribution of high chromogranin A serum levels in patients with nonmetastatic and metastatic prostate adenocarcinoma
    Alessandro Sciarra
    Department of Urology, University La Sapienza, Rome, Italy
    Urol Int 82:147-51. 2009
    ..We analyzed the incidence of elevated serum levels of chromogranin A (CgA) (as marker of neuroendocrine activity) in nonmetastatic and metastatic prostate cancer populations...
  25. doi request reprint 2D and 3D T2-weighted MR sequences for the assessment of neurovascular bundle changes after nerve-sparing radical retropubic prostatectomy with erectile function correlation
    Valeria Panebianco
    Department of Radiological Sciences, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy
    Eur Radiol 19:220-9. 2009
    ..7% class IV. In all cases, the correlation and regression analysis between the 3D T2 ISO and IIEF-5 score resulted in higher coefficients values. The 3D sequence correlated most closely with patients' grading of erectile function...
  26. ncbi request reprint Which patients with prostate cancer are actually candidates for hormone therapy?
    Alessandro Sciarra
    Department of Urology U Bracci, University La Sapienza, Rome, Italy
    Int Braz J Urol 30:455-65. 2004
    ..Therapies that resist for longer periods without the production of a hormone-refractory disease are also required...
  27. doi request reprint Etoricoxib and intermittent androgen deprivation therapy in patients with biochemical progression after radical prostatectomy
    Franco Di Silverio
    Department of Urology, University of Rome, Rome, Italy
    Urology 71:947-51. 2008
    ....
  28. ncbi request reprint Variation in chromogranin A serum levels during intermittent versus continuous androgen deprivation therapy for prostate adenocarcinoma
    Alessandro Sciarra
    Department of Urology U Bracci, University La Sapienza, Rome, Italy
    Prostate 55:168-79. 2003
    ..The aim of this study was to verify whether the intermittent administration of androgen deprivation (IAD) reduces the risk of CgA increase in PC cases treated with complete androgen deprivation (CAD)...
  29. doi request reprint Use of multiparametric MR with neurovascular bundle evaluation to optimize the oncological and functional management of patients considered for nerve-sparing radical prostatectomy
    Valeria Panebianco
    Department of Radiology, University Sapienza, Rome, Italy
    J Sex Med 9:2157-66. 2012
    ..Multiparametric magnetic resonance imaging (MRI) promises to make it a successful imaging tool for improving many aspects of prostate cancer management...
  30. doi request reprint Value of magnetic resonance spectroscopy (MSR) and dynamic contrast-enhanced magnetic resonance (DCEMR) imaging for the characterization of high-grade prostatic intraepithelial neoplasia (HGPIN) foci
    Alessandro Sciarra
    Department of Urology, University Sapienza, Rome, Italy
    Urol Oncol 29:634-40. 2011
    ..The aim of this study was to analyze the magnetic resonance spectroscopy (MSR) and dynamic contrast-enhanced magnetic resonance (DCEMR) imaging features of isolated HGPIN lesions...
  31. ncbi request reprint Somatostatin analogues and estrogens in the treatment of androgen ablation refractory prostate adenocarcinoma
    Alessandro Sciarra
    Department of Urology, University La Sapienza, Rome, Italy
    J Urol 172:1775-83. 2004
    ..Of note, salvage chemotherapy can extend the median survival of approximately 10 months in patients with stage D3. Therefore, novel therapeutic strategies that target the molecular basis of androgen resistance are required...
  32. doi request reprint Prostate cancer gene 3 and multiparametric magnetic resonance can reduce unnecessary biopsies: decision curve analysis to evaluate predictive models
    Gian Maria Busetto
    Department of Urology, Sapienza University of Rome, Rome, Italy
    Urology 82:1355-60. 2013
    ..Furthermore, multiparametric magnetic resonance imaging (mMRI) has the ability to better describe several aspects of PC...
  33. doi request reprint Prostate cancer: 1HMRS-DCEMR at 3T versus [(18)F]choline PET/CT in the detection of local prostate cancer recurrence in men with biochemical progression after radical retropubic prostatectomy (RRP)
    Valeria Panebianco
    Dept of Radiological Sciences, Sapienza University of Rome, V le Regina Elena, 324 00161 Rome, Italy
    Eur J Radiol 81:700-8. 2012
    ....
  34. ncbi request reprint Combination therapy of ethinylestradiol and somatostatin analogue reintroduces objective clinical responses and decreases chromogranin a in patients with androgen ablation refractory prostate cancer
    Franco Di Silverio
    Department of Urology U Bracci, University La Sapienza, V Nomentana 233, 00161 Rome, Italy
    J Urol 170:1812-6. 2003
    ..We evaluated whether a combination therapy of ethinylestradiol and somatostatin analogue can reintroduce objective clinical responses in patients with metastatic androgen ablation refractory prostate cancer (PC)...
  35. ncbi request reprint Long-term response to combination therapy with estramustine and somatostatin analogue in a patient with androgen ablation-refractory prostate cancer
    Costantino Cerulli
    Department of Urology, University La Sapienza, Rome, Italy
    Urology 64:1231.e1-3. 2004
    ..9 mg intramuscularly every 4 weeks. After 33 months of follow-up, the patient was alive without clinical disease progression, and his prostate-specific antigen and chromogranin A level was 0.10 and 12 ng/mL, respectively...
  36. doi request reprint Biopsy-derived Gleason artifact and prostate volume: experience using ten samples in larger prostates
    Alessandro Sciarra
    Department of Urology, University La Sapienza of Rome, Rome, Italy
    Urol Int 80:145-50. 2008
    ..To verify whether a significant relationship between the risk of Gleason upgrading and the prostate volume remains when the number of biopsies is increased for larger prostate volumes...
  37. doi request reprint Comparison of chromogranin A, insulin-like growth factor 1 and prostate-specific antigen serum markers in prostate adenocarcinoma and benign prostatic hyperplasia
    Alessandro Sciarra
    Department of Urology, University of Rome, Rome, Italy
    Urol Int 80:68-73. 2008
    ..To compare serum chromogranin A (CgA) and insulin-like growth factor 1 (IGF-1) with the classical prostate-specific antigen (PSA) marker in clinically localized prostate adenocarcinomas...
  38. doi request reprint Use of 3D T2-weighted MR sequences for the assessment of neurovascular bundle changes after nerve-sparing radical retropubic prostatectomy (RRP): a potential diagnostic tool for optimal management of erectile dysfunction after RRP
    Alessandro Sciarra
    Department of Urology, University La Sapienza, Rome 00198, Italy
    J Sex Med 6:1430-7. 2009
    ..Erectile dysfunction (ED) is one of the complications after radical retropubic prostatectomy (RRP), and recovery of erectile function is quantitatively related to the preservation of the neurovascular bundles (NVBs)...
  39. doi request reprint Modern role of magnetic resonance and spectroscopy in the imaging of prostate cancer
    Alessandro Sciarra
    Department of Urology, University Sapienza, Rome, Italy
    Urol Oncol 29:12-20. 2011
    ....
  40. ncbi request reprint Role of radical retropubic prostatectomy in patients with locally advanced prostate cancer: the influence of Gleason score 8-10
    Alessandro Sciarra
    Department of Urology U Bracci, University La Sapienza, V Policlinico, I 00161 Rome, Italy
    Urol Int 70:186-94. 2003
    ..To define whether in locally advanced prostate cancer submitted to radical retropubic prostatectomy (RRP) the presence of a Gleason score 8-10 represents an index of high risk for progression and cancer-specific death...
  41. doi request reprint Comparative analysis of multiparametric magnetic resonance and PET-CT in the management of local recurrence after radical prostatectomy for prostate cancer
    Andrea Alfarone
    Department of Urology, University Sapienza, Rome, Italy
    Crit Rev Oncol Hematol 84:109-21. 2012
    ..Our aim was to assess whether multiparametric magnetic resonance and PET-CT can have a role in detecting local recurrence in patients with biochemical recurrence after radical prostatectomy...
  42. ncbi request reprint Adjuvant therapy with sorafenib in bone metastases bilateral renal carcinoma: a case report
    Alessandro Sciarra
    Department of Urology, University of Rome, Italy
    Eur Urol 52:597-9. 2007
    ..At 12-mo follow-up there was a significant improvement in patient performance status and no evidence of clinical progression...
  43. doi request reprint Long-term experience with an anatomical anterograde approach to radical prostatectomy: results in terms of positive margin rate
    Alessandro Sciarra
    Department Urology, University La Sapienza, Rome, Italy
    Urol Int 80:151-6. 2008
    ..To evaluate the effect of an anterograde approach to radical retropubic prostatectomy (RRP) in terms of positive surgical margins (SM+)...
  44. doi request reprint Early recovery of urinary continence after radical prostatectomy using early pelvic floor electrical stimulation and biofeedback associated treatment
    Gianna Mariotti
    Department of Urology, University Sapienza of Rome, Rome, Italy
    J Urol 181:1788-93. 2009
    ..We analyzed the benefit of the early combined use of functional pelvic floor electrical stimulation and biofeedback in terms of time to recovery and rate of continence after radical prostatectomy...
  45. ncbi request reprint Prostate growth and inflammation
    Alessandro Sciarra
    Department of Urology U Bracci, University La Sapienza, Via Nomentana 233, Rome, Italy
    J Steroid Biochem Mol Biol 108:254-60. 2008
    ..Inflammation is thought to incite carcinogenesis by causing cell and genome damage, promoting cellular turnover...
  46. doi request reprint In vivo 3D neuroanatomical evaluation of periprostatic nerve plexus with 3T-MR Diffusion Tensor Imaging
    Valeria Panebianco
    Department of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy
    Eur J Radiol 82:1677-82. 2013
    ....
  47. doi request reprint Prostate cancer recurrence after radical prostatectomy: the role of 3-T diffusion imaging in multi-parametric magnetic resonance imaging
    Valeria Panebianco
    Department of Radiological Sciences, Oncology and Pathology, Sapienza, University of Rome, V le Regina Elena, 324, 00161 Rome, Italy
    Eur Radiol 23:1745-52. 2013
    ..To validate the role of 3-T diffusion-weighted imaging (DWI) in the detection of local prostate cancer recurrence after radical prostatectomy (RP)...
  48. ncbi request reprint Use of cyclooxygenase-2 inhibitor for prevention of urethral strictures secondary to transurethral resection of the prostate
    Alessandro Sciarra
    Department of Urology, University La Sapienza, Rome, Italy
    Urology 66:1218-22. 2005
    ..At urethroscopy, stenosis of the urethra with a circumference of less than 19 mm was defined as stricture...
  49. ncbi request reprint Distribution of inflammation, pre-malignant lesions, incidental carcinoma in histologically confirmed benign prostatic hyperplasia: a retrospective analysis
    Franco Di Silverio
    Department of Urology U Bracci, University La Sapienza, V Policlinico, 00161, Rome, Italy
    Eur Urol 43:164-75. 2003
    ..We analyze our experience on BPH through 20 years of histopathological examinations performed by the same pathologist...
  50. ncbi request reprint Combination therapy with rofecoxib and finasteride in the treatment of men with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH)
    Franco Di Silverio
    Department Urology, University La Sapienza, Urology U Bracci, V Policlinico, 00161 Rome, Italy
    Eur Urol 47:72-8; discussion 78-9. 2005
    ..The aim of this study is to analyze whether combination therapy with rofecoxib, a COX-2 inhibitor, and finasteride offers an advantage compared to finasteride monotherapy in patients with BPH...
  51. doi request reprint Classification of prostatic diseases by means of multivariate analysis on in vivo proton MRSI and DCE-MRI data
    MariaCristina Valerio
    Department of Chemistry, University of Rome La Sapienza, Rome, Italy
    NMR Biomed 22:1036-46. 2009
    ..From a more theoretical point of view, the complementation of a single biomarker approach with an integrated picture of the entire metabolic and dynamic profile allows for a more realistic appreciation of pathological entities...
  52. doi request reprint A chemosensitivity test to individualize intravesical treatment for non-muscle-invasive bladder cancer
    Paola Gazzaniga
    Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
    BJU Int 104:184-8. 2009
    ..To describe the design of a new chemosensitivity assay based on the expression of genes involved in the resistance to standard intravesical regimens, to allow individualization of therapy for high-risk non-muscle-invasive bladder cancer...
  53. doi request reprint Bladder carcinoma: MDCT cystography and virtual cystoscopy
    Valeria Panebianco
    Department of Radiological Sciences, University of Rome, Italy
    Abdom Imaging 35:257-64. 2010
    ..We presents the CT cystography findings with virtual endoscopy correlation and bladder carcinoma appearance...
  54. ncbi request reprint Inflammation and chronic prostatic diseases: evidence for a link?
    Alessandro Sciarra
    Department of Urology, University La Sapienza, Rome, Italy
    Eur Urol 52:964-72. 2007
    ..Does prostate inflammation represent a significant factor for the development and the progression of both BPH and PCa? Are data available now to sustain the identification of prostate inflammation as a risk factor for prostate diseases?..
  55. ncbi request reprint Chromogranin A expression in familial versus sporadic prostate cancer
    Alessandro Sciarra
    Department of Urology, University of La Sapienza, Rome, Italy
    Urology 66:1010-4. 2005
    ..To evaluate whether a significant difference in chromogranin A (CgA) levels exist between patients with familial and sporadic cancer...
  56. ncbi request reprint Dynamic contrast-enhanced magnetic resonance imaging in the early evaluation of anti-angiogenic therapy in metastatic renal cell carcinoma
    Valeria Panebianco
    Department of Radiological Sciences, Oncology and Pathology, Sapienza, University of Rome, Viale Regina Elena 324, 00161, Rome, Italy
    Anticancer Res 33:5663-6. 2013
    ..To evaluate the efficacy of dynamic contrast-enhanced magnetic resonance (DCE-MR) in the response to anti-angiogenic-targeted agents in patients with metastatic renal cell cancer (mRCC)...
  57. ncbi request reprint New anti-angiogenic targeted therapy in advanced renal cell carcinoma (RCC): current status and future prospects
    Alessandro Sciarra
    Department U Bracci, University Sapienza, Rome, Italy
    Rev Recent Clin Trials 3:97-103. 2008
    ..To address the rationale for anti-angiogenic targeted therapies in advanced RCC...
  58. ncbi request reprint Antiandrogen monotherapy: recommendations for the treatment of prostate cancer
    Alessandro Sciarra
    Department of Urology, University La Sapienza, Rome, Italy
    Urol Int 72:91-8. 2004
    ..The concept of antiandrogens as monotherapy for the treatment of prostate cancer is discussed...
  59. doi request reprint The role of chronic prostatic inflammation in the pathogenesis and progression of benign prostatic hyperplasia (BPH)
    Giorgio Gandaglia
    Department of Urology, Urological Research Institute, University Vita Salute San Raffaele, San Raffaele Scientific Institute, Milan, Italy
    BJU Int 112:432-41. 2013
    ..In this context, clinical, imaging and laboratory parameters might be used alone or in combination to identify patients that harbour chronic prostatic inflammation. ..
  60. ncbi request reprint Comparison between ultrasound-guided and digital-guided anesthesia before prostatic biopsy
    Giuseppe D'Eramo
    Department of Urology U Bracci, University Sapienza, Rome, Italy
    Arch Ital Urol Androl 84:260-2. 2012
    ..Our target in this study is to evaluate the efficacy of ultrasound (US)-guided anesthesia in comparison it to the digital-guided one, considering pain and discomfort reduction, during prostate biopsy...
  61. ncbi request reprint Histopathological aspects of transitional cell carcinoma of the bladder: analysis of 20 years experience
    Alessandro Sciarra
    Department of Urology, U Bracci University La Sapienza, Rome, Italy
    Int J Urol 11:467-75. 2004
    ....
  62. ncbi request reprint Characterization of circulating blood dendritic cell subsets DC123+ (lymphoid) and DC11C+ (myeloid) in prostate adenocarcinoma patients
    Alessandro Sciarra
    Department of Urology, University of La Sapienza, Rome, Italy
    Prostate 67:1-7. 2007
    ..We verified whether prostate adenocarcinoma produces specific modifications in DC subsets count...
  63. pmc Randomized trial comparing an anterograde versus a retrograde approach to open radical prostatectomy: results in terms of positive margin rate
    Alessandro Sciarra
    Department Urology, University La Sapienza, Rome, Italy
    Can Urol Assoc J 4:192-8. 2010
    ..We evaluated the effect of an anterograde versus retrograde approach to RRP and specifically focused on the incidence of SM+...
  64. ncbi request reprint Histopathological aspects associated with the diagnosis of benign prostatic hyperplasia: clinical implications
    Alessandro Sciarra
    Department of Urology, University La Sapienza, Rome
    Urol Int 69:253-62. 2002
  65. doi request reprint The controversial relationship between benign prostatic hyperplasia and prostate cancer: the role of inflammation
    Cosimo De Nunzio
    Department of Urology, Sant Andrea Hospital, University La Sapienza, Rome, Italy
    Eur Urol 60:106-17. 2011
    ..Recent data suggest that prostatic inflammation is involved in the pathogenesis and progression of both conditions...