Genomes and Genes
Affiliation: San Raffaele Scientific Institute
- Mother-to-child transmission of HIV-1: advances and controversies of the twentieth centuriesG Scarlatti
Unit of Viral Evolution and Transmission, DIBIT San Raffaele Scientific Institute Via Olgettina, 58, 20132 Milano, Italy
AIDS Rev 6:67-78. 2004..Although global access to ARV therapy certainly remains the primary goal to achieve the immediate reduction of MTCT of HIV-1, it is also evident that new and additional innovative strategies are needed...
- International network for comparison of HIV neutralization assays: the NeutNet reportEva Maria Fenyo
Department of Microbiology, Dermatology and Infection, University of Lund, Lund, Sweden
PLoS ONE 4:e4505. 2009..To address this, an international collaboration (NeutNet) involving 18 independent participants was organized to compare different assays...
- Rational design of HIV vaccines and microbicides: report of the EUROPRISE annual conference 2011Nicolas Ruffin
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
J Transl Med 10:144. 2012..These - necessarily overlapping topics - are comprehensively summarised by the Europrise students in the context of other recent exciting data...
- HIV-1 co-receptor usage: influence on mother-to-child transmission and pediatric infectionMariangela Cavarelli
Unit of Viral Evolution and Transmission, Division of Immunology, Transplant and Infectious Diseases, San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy
J Transl Med 9:S10. 2011..Studies are needed to address more in specific the relevance of these factors in HIV-1 MTCT and pediatric infection of non-B subtypes...
- Rational design of HIV vaccines and microbicides: report of the EUROPRISE network annual conference 2010Sarah Brinckmann
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Nobels väg, Stockholm, 171 77, Sweden
J Transl Med 9:40. 2011....
- Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conferenceBritta Wahren
Karolinska Institute, Stockholm, Sweden
J Transl Med 8:72. 2010..Since training is a major task of the Network, the students of the EUROPRISE PhD program summarized certain presentations and their view of the conference in this paper...
- Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotypeA Bjorndal
Microbiology and Tumorbiology Center, Karolinska Institute, Stockholm, Sweden
J Virol 71:7478-87. 1997..The results show that all 36 primary HIV-1 isolates induce syncytia, provided that target cells carry the particular coreceptor required by the virus...
- Length variation of glycoprotein 120 V2 region in relation to biological phenotypes and coreceptor usage of primary HIV type 1 isolatesM Jansson
Microbiology and Tumor Biology Center, Karolinska Institute, 171 77 Stockholm, Sweden
AIDS Res Hum Retroviruses 17:1405-14. 2001....
- HIV type 1 chemokine receptor usage in mother-to-child transmissionF Salvatori
Unit of Immunobiology of HIV, DIBIT, San Raffaele Scientific Institute, 20132 Milan, Italy
AIDS Res Hum Retroviruses 17:925-35. 2001....
- Human immunodeficiency virus type 1 mother-to-child transmission and prevention: successes and controversiesM Cavarelli
Unit of Viral Evolution and Transmission, DITID, San Raffaele Scientific Institute, Milan, Italy
J Intern Med 270:561-79. 2011....
- In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppressionG Scarlatti
Unit of Immunobiology of HIV, DIBIT, San Raffaele Scientific Institute, Milan, Italy
Nat Med 3:1259-65. 1997..These results suggest an adaptive evolution of HIV-1 in vivo, leading to escape from the control of the antiviral C-C chemokines...
- Polymorphisms in the MBL2 promoter correlated with risk of HIV-1 vertical transmission and AIDS progressionM Boniotto
Genetic Service, IRCCS Burlo Garofolo and Chair of Genetics, University of Trieste, Via dell Istria 65 1, 34137 Trieste, Italy
Genes Immun 1:346-8. 2000..Also a 6 bp deletion at position -328 was correlated with HIV-1 infection. This study indicates that the promoter of the MBL2 gene influences vertical transmission of HIV and the course of perinatal infection...
- Follow-up of vertically HIV-1-infected long-surviving childrenF Salvini
Department of Pediatrics G. e D. De Marchi, University of Milan, Italy
AIDS Patient Care STDS 15:59-65. 2001..A switch to syncytia-inducing phenotype was observed only in 2 cases during the follow-up, but their clinical status did not change at follow-up...
- Enhanced HIV infectivity and changes in GP120 conformation associated with viral incorporation of human leucocyte antigen class I moleculesA Cosma
Centre Intégré de Recherches Biocliniques sur le SIDA, Paris, France
AIDS 13:2033-42. 1999..Virion-associated HLA class II and intercellular adhesion molecule-1 enhance the infectivity of T-cell line-adapted (TCLA) viruses. No role for virion-associated HLA class I molecules has yet been identified...
- Mother-to-child transmission of HIV: developing integration of healthcare programmes with clinical, social and basic research studies. Report of the International Workshop held at Chobe Marina Lodge, Kasane, Botswana, 21-25 January 2003E Menu
Acta Paediatr 92:1343-8. 2003..Future initiatives should include integrating specialists and people with diverse backgrounds and targeting their scientific and programmatic ideas to address real-world problems in the area of MTCT of HIV-1...