G Perseghin

Summary

Affiliation: San Raffaele Scientific Institute
Country: Italy

Publications

  1. pmc Association between plasma monocyte chemoattractant protein-1 concentration and cardiovascular disease mortality in middle-aged diabetic and nondiabetic individuals
    Lorenzo Piemonti
    Diabetes Research Institute, Istituto Scientifico H San Raffaele, Milan, Italy
    Diabetes Care 32:2105-10. 2009
  2. pmc Prevalence, metabolic features, and prognosis of metabolically healthy obese Italian individuals: the Cremona Study
    Giliola Calori
    Division of Metabolic and Cardiovascular Sciences, Istituto Scientifico H San Raffaele, Milan, Italy
    Diabetes Care 34:210-5. 2011
  3. doi Insulin resistance/hyperinsulinemia and cancer mortality: the Cremona study at the 15th year of follow-up
    Gianluca Perseghin
    Division of Metabolic and Cardiovascular Sciences, Istituto Scientifico H San Raffaele, Milan, Italy
    Acta Diabetol 49:421-8. 2012
  4. doi Left ventricular function and energy homeostasis in patients with type 1 diabetes with and without microvascular complications
    Gianluca Perseghin
    Internal Medicine, Section of Nutrition, Istituto Scientifico San Raffaele, Milano, Italy
    Int J Cardiol 154:111-5. 2012
  5. ncbi Increased serum resistin in elite endurance athletes with high insulin sensitivity
    G Perseghin
    Internal Medicine, Section of Nutrition Metabolism and Unit of Clinical Spectroscopy, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    Diabetologia 49:1893-900. 2006
  6. ncbi Insulin resistance and whole body energy homeostasis in obese adolescents with fatty liver disease
    Gianluca Perseghin
    Division of Internal Medicine, Section of Nutrition Metabolism, Milan, Italy
    Am J Physiol Endocrinol Metab 291:E697-703. 2006
  7. ncbi Serum resistin and hepatic fat content in nondiabetic individuals
    Gianluca Perseghin
    Internal Medicine, Section of Nutrition Metabolism and Unit of Clinical Spectroscopy, San Raffaele Scientific Institute, 20132 Milan, Italy
    J Clin Endocrinol Metab 91:5122-5. 2006
  8. ncbi Reduced intrahepatic fat content is associated with increased whole-body lipid oxidation in patients with type 1 diabetes
    G Perseghin
    Internal Medicine Section of Nutrition Metabolism, Via Olgettina 60, 20132, Milan, Italy
    Diabetologia 48:2615-21. 2005
  9. ncbi Habitual physical activity is associated with intrahepatic fat content in humans
    Gianluca Perseghin
    Internal Medicine, Section of Nutrition Metabolism, San Raffaele Scientific Institute, Milan, Italy
    Diabetes Care 30:683-8. 2007
  10. ncbi Abnormal left ventricular energy metabolism in obese men with preserved systolic and diastolic functions is associated with insulin resistance
    Gianluca Perseghin
    Section of Nutrition Metabolism, Department of Internal Medicine, Istituto Scientifico San Raffaele, Milano, Italy
    Diabetes Care 30:1520-6. 2007

Detail Information

Publications54

  1. pmc Association between plasma monocyte chemoattractant protein-1 concentration and cardiovascular disease mortality in middle-aged diabetic and nondiabetic individuals
    Lorenzo Piemonti
    Diabetes Research Institute, Istituto Scientifico H San Raffaele, Milan, Italy
    Diabetes Care 32:2105-10. 2009
    ..Monocyte chemoattractant protein-1 (MCP-1/CCL2) is a chemokine involved into the pathogenesis of atherosclerosis and has prognostic value in the acute and chronic phases in patients with acute coronary syndromes...
  2. pmc Prevalence, metabolic features, and prognosis of metabolically healthy obese Italian individuals: the Cremona Study
    Giliola Calori
    Division of Metabolic and Cardiovascular Sciences, Istituto Scientifico H San Raffaele, Milan, Italy
    Diabetes Care 34:210-5. 2011
    ..Some obese individuals have normal insulin sensitivity. It is controversial whether this phenotype is associated with increased all-cause mortality risk...
  3. doi Insulin resistance/hyperinsulinemia and cancer mortality: the Cremona study at the 15th year of follow-up
    Gianluca Perseghin
    Division of Metabolic and Cardiovascular Sciences, Istituto Scientifico H San Raffaele, Milan, Italy
    Acta Diabetol 49:421-8. 2012
    ..61 95% CI: 1.73-3.94; P < 0.0001). Age- and sex-adjusted analysis showed that hyperinsulinemia/insulin resistance is associated with cancer mortality independently of diabetes, obesity/visceral obesity and the metabolic syndrome...
  4. doi Left ventricular function and energy homeostasis in patients with type 1 diabetes with and without microvascular complications
    Gianluca Perseghin
    Internal Medicine, Section of Nutrition, Istituto Scientifico San Raffaele, Milano, Italy
    Int J Cardiol 154:111-5. 2012
    ..This study was performed to assess left ventricular (LV) energy metabolism and function in patients with type 1 diabetes with or without overt microvascular complications...
  5. ncbi Increased serum resistin in elite endurance athletes with high insulin sensitivity
    G Perseghin
    Internal Medicine, Section of Nutrition Metabolism and Unit of Clinical Spectroscopy, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    Diabetologia 49:1893-900. 2006
    ....
  6. ncbi Insulin resistance and whole body energy homeostasis in obese adolescents with fatty liver disease
    Gianluca Perseghin
    Division of Internal Medicine, Section of Nutrition Metabolism, Milan, Italy
    Am J Physiol Endocrinol Metab 291:E697-703. 2006
    ..In contrast, the rearrangement of whole body substrate oxidation in these youngsters appeared to be an independent feature...
  7. ncbi Serum resistin and hepatic fat content in nondiabetic individuals
    Gianluca Perseghin
    Internal Medicine, Section of Nutrition Metabolism and Unit of Clinical Spectroscopy, San Raffaele Scientific Institute, 20132 Milan, Italy
    J Clin Endocrinol Metab 91:5122-5. 2006
    ..Serum resistin concentration is increased in patients with nonalcoholic fatty liver disease in proportion with the histological severity of the disease, but the relevance of the contribution of fatty liver per se is undetermined...
  8. ncbi Reduced intrahepatic fat content is associated with increased whole-body lipid oxidation in patients with type 1 diabetes
    G Perseghin
    Internal Medicine Section of Nutrition Metabolism, Via Olgettina 60, 20132, Milan, Italy
    Diabetologia 48:2615-21. 2005
    ..We assessed whether these patients are also characterised by intrahepatic fat accumulation and abnormal fat oxidation...
  9. ncbi Habitual physical activity is associated with intrahepatic fat content in humans
    Gianluca Perseghin
    Internal Medicine, Section of Nutrition Metabolism, San Raffaele Scientific Institute, Milan, Italy
    Diabetes Care 30:683-8. 2007
    ..The purpose of this study was to examine the association of habitual physical activity, insulin resistance, and adiponectin with IHF content...
  10. ncbi Abnormal left ventricular energy metabolism in obese men with preserved systolic and diastolic functions is associated with insulin resistance
    Gianluca Perseghin
    Section of Nutrition Metabolism, Department of Internal Medicine, Istituto Scientifico San Raffaele, Milano, Italy
    Diabetes Care 30:1520-6. 2007
    ..We evaluated left ventricular (LV) structure/geometry and function in relation to energy metabolism and cardiovascular risk factors in overweight/obese men using magnetic resonance techniques...
  11. ncbi Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver
    Gianluca Perseghin
    Department of Internal Medicine, Section of Nutrition Metabolism, San Raphael Scientific Institute, Milan, Italy
    Hepatology 47:51-8. 2008
    ..016). In conclusion, in newly found individuals with fatty liver, fat was accumulated in the epicardial area and despite normal LV morphological features and systolic and diastolic functions, they had abnormal LV energy metabolism...
  12. ncbi Effect of the sporting discipline on the right and left ventricular morphology and function of elite male track runners: a magnetic resonance imaging and phosphorus 31 spectroscopy study
    Gianluca Perseghin
    Internal Medicine Section of Nutrition Metabolism, San Raphael Scientific Institute, Milan, Italy
    Am Heart J 154:937-42. 2007
    ..This study was undertaken to assess the left ventricular (LV) and right ventricular (RV) morphology and function and the LV high-energy phosphates of athletes trained to a sustained power or aerobic exercise...
  13. ncbi Serum retinol-binding protein-4, leptin, and adiponectin concentrations are related to ectopic fat accumulation
    Gianluca Perseghin
    Internal Medicine Section of Nutrition Metabolism, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    J Clin Endocrinol Metab 92:4883-8. 2007
    ..Serum retinol-binding protein 4 (RBP-4), leptin, and adiponectin concentrations identify insulin resistance in varied conditions, but their relationships with insulin sensitivity and ectopic fat accumulation are unclear...
  14. doi Left ventricular function and energy metabolism in middle-aged men undergoing long-lasting sustained aerobic oxidative training
    G Perseghin
    Internal Medicine Section of Nutrition Metabolism, IRCCS H San Raffaele, Milan Italy
    Heart 95:630-5. 2009
    ..In this study we aimed to assess whether in middle-aged men involved in regular and long lasting physical activity these alterations were attenuated...
  15. doi Elevated fasting plasma C-peptide occurs in non-diabetic individuals with fatty liver, irrespective of insulin resistance
    G Perseghin
    Internal Medicine Section of Nutrition Metabolism, San Raffaele Scientific Institute, 20132, Milan, Italy
    Diabet Med 26:847-54. 2009
    ..This study was undertaken to test whether fasting C-peptide, an index of fasting B-cell function, was related to intra-hepatic fat (IHF) content in non-diabetic humans...
  16. doi Free leptin index and thyroid function in male highly trained athletes
    Gianluca Perseghin
    Department of Sport, Nutrition and Health, Universita degli Studi di Milano, via Kramer 4 a 20129 Milan, Italy
    Eur J Endocrinol 161:871-6. 2009
    ..The aim of this study was to assess the relationships between thyroid function, whole body energy metabolism, and adipokines--mainly leptin and its receptor, sOB-R...
  17. ncbi Insulin resistance, intramyocellular lipid content, and plasma adiponectin in patients with type 1 diabetes
    Gianluca Perseghin
    Section of Nutrition Metabolism, Università Vita e Salute San Raffaele IRCCS H San Raffaele, 20132 Milan, Italy
    Am J Physiol Endocrinol Metab 285:E1174-81. 2003
    ....
  18. doi The role of non-alcoholic fatty liver disease in cardiovascular disease
    Gianluca Perseghin
    Internal Medicine, Istituto Scientifico H San Raffaele, Department of Sport, Nutrition and Health Sciences, Universita degli Studi di Milano, Milan, Italy
    Dig Dis 28:210-3. 2010
    ..The aim of this article is to summarize the available data linking non-alcoholic fatty liver disease (NAFLD) with CVD...
  19. ncbi Cross-sectional assessment of the effect of kidney and kidney-pancreas transplantation on resting left ventricular energy metabolism in type 1 diabetic-uremic patients: a phosphorous-31 magnetic resonance spectroscopy study
    Gianluca Perseghin
    Division of Internal Medicine Section of Nutrition Metabolism, Universita Vita e Salute San Raffaele, Milan, Italy
    J Am Coll Cardiol 46:1085-92. 2005
    ....
  20. ncbi Muscle lipid metabolism in the metabolic syndrome
    Gianluca Perseghin
    Internal Medicine Section of Nutrition Metabolism and Unit of Clinical Spectroscopy, Istituto Scientifico H San Raffaele via Olgettina 60, Milan, Italy
    Curr Opin Lipidol 16:416-20. 2005
    ....
  21. ncbi Assessment of insulin sensitivity based on a fasting blood sample in men with liver cirrhosis before and after liver transplantation
    Gianluca Perseghin
    Nutrition Metabolism, Istituto Scientifico H San Raffaele, Milan, Italy
    Transplantation 76:697-702. 2003
    ..This study aimed to test whether these simple indices are reliable measures of insulin sensitivity in patients with liver cirrhosis before and after liver transplantation (LTx)...
  22. ncbi Contribution of abnormal insulin secretion and insulin resistance to the pathogenesis of type 2 diabetes in myotonic dystrophy
    Gianluca Perseghin
    Section of Nutrition Metabolism and Unit of Clinical Spectroscopy, Istituto Scientifico H San Raffaele, Milan, Italy
    Diabetes Care 26:2112-8. 2003
    ..MyD is dominantly inherited and is due to heterozygosity for a trinucleotide repeat expansion mutation in a protein kinase gene able to induce derangement of RNA metabolism responsible of an aberrant insulin receptor expression...
  23. ncbi Incorporation of the fasting plasma FFA concentration into QUICKI improves its association with insulin sensitivity in nonobese individuals
    G Perseghin
    Division of Internal Medicine, Biometrical Unit, Universita Vita e Salute San Raffaele, Universita degli Studi di Milano, Milan, Italy 20132
    J Clin Endocrinol Metab 86:4776-81. 2001
    ..Further investigation is needed to ascertain its applicability to patients with obesity and type 2 diabetes...
  24. ncbi Gender factors affect fatty acids-induced insulin resistance in nonobese humans: effects of oral steroidal contraception
    G Perseghin
    Divisions of Internal Medicine I, Unit of Clinical Spectroscopy, Universita Vita e Salute San Raffaele, Istituto Scientifico H San Raffaele, 20132 Milan, Italy
    J Clin Endocrinol Metab 86:3188-96. 2001
    ....
  25. ncbi Fasting blood sample-based assessment of insulin sensitivity in kidney-pancreas-transplanted patients
    Gianluca Perseghin
    Nutrition Metabolism, Istituto Scientifico H San Raffaele, Milan, Italy
    Diabetes Care 25:2207-11. 2002
    ..To ascertain whether simple indexes of insulin sensitivity based on a fasting blood sample may be reliable measures of insulin sensitivity in combined kidney-pancreas- transplanted patients...
  26. ncbi Normal insulin sensitivity and IMCL content in overweight humans are associated with higher fasting lipid oxidation
    Gianluca Perseghin
    Division of Nutrition Metabolism, Universita Vita e Salute San Raffaele, Istituto Scientifico H San Raffaele, 20132 Milan, Italy
    Am J Physiol Endocrinol Metab 283:E556-64. 2002
    ....
  27. ncbi Postabsorptive and insulin-stimulated energy and protein metabolism in patients with myotonic dystrophy type 1
    Gianluca Perseghin
    Internal Medicine Section of Nutrition Metabolism, Universita Vita e Salute San Raffaele, Istituto Scientifico H San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    Am J Clin Nutr 80:357-64. 2004
    ..We reported recently that the severity of the impairment in insulin-stimulated glucose metabolism in these patients was overestimated...
  28. ncbi Contribution of reduced insulin sensitivity and secretion to the pathogenesis of hepatogenous diabetes: effect of liver transplantation
    G Perseghin
    Department of Intermal Medicine I, Istituto Scientifico H San Raffaele, National Cancer Institute, Milan, Italy
    Hepatology 31:694-703. 2000
    ....
  29. ncbi Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents
    G Perseghin
    Division of Internal Medicine, Istituto Scientifico H San Raffaele, Milan, Italy
    Diabetes 48:1600-6. 1999
    ....
  30. ncbi Resting energy expenditure in diabetic and nondiabetic patients with liver cirrhosis: relation with insulin sensitivity and effect of liver transplantation and immunosuppressive therapy
    Gianluca Perseghin
    Division of Internal Medicine, Istituto H San Raffaele, Milan, Italy
    Am J Clin Nutr 76:541-8. 2002
    ..Hypermetabolism, insulin resistance, and diabetes are common in patients with liver cirrhosis...
  31. ncbi Reduced whole-body lipid oxidation is associated with insulin resistance, but not with intramyocellular lipid content in offspring of type 2 diabetic patients
    G Lattuada
    Internal Medicine Section of Nutrition Metabolism, Scientific Institute H San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    Diabetologia 48:741-7. 2005
    ..Intramyocellular lipid accumulation and insulin resistance are thought to be due to reduced lipid oxidation in a human model of high risk of developing type 2 diabetes...
  32. doi Impaired left ventricular energy metabolism in patients with hypertrophic cardiomyopathy is related to the extension of fibrosis at delayed gadolinium-enhanced magnetic resonance imaging
    A Esposito
    Department of Radiology, San Raffaele Scientific Institute, Vita Salute San Raffaele University, Via Olgettina 60, 20132, Milan, Italy
    Heart 95:228-33. 2009
    ..We sought to ascertain whether in HCM patients the abnormal features of left ventricular (LV) interstitial space revealed by DE-MRI correlated with impaired LV energy metabolism shown at (31)P-MRS...
  33. doi Effect of L-acetylcarnitine on body composition in HIV-related lipodystrophy
    S Benedini
    Metabolism and Nutrition Unit, San Raffaele Scientific Institute, Milan, Italy
    Horm Metab Res 41:840-5. 2009
    ..05). Eight months of L-acetylcarnitine treatment increased lipid oxidation, decreased intramyocellular triglyceride content, and induced a more physiological distribution of fat deposits...
  34. ncbi Evaluation of insulin release and insulin sensitivity through oral glucose tolerance test: differences between NGT, IFG, IGT, and type 2 diabetes mellitus. A cross-sectional and follow-up study
    A E Pontiroli
    Dipartimento di Medicina Interna, Ospedale San Paolo, Universita di Milano, Via A Di Rudini 8, I 20142, Milan, Italy
    Acta Diabetol 41:70-6. 2004
    ..IFG, IGT and type 2 diabetes mellitus are characterized by reduced IR compared to IS...
  35. ncbi Atrial natriuretic peptide in diabetic and nondiabetic patients with and without heart transplantation
    S Benedini
    Nutrition and Metabolism Unit, San Raffaele Scientific Institute, Via Olgettina 60, Milan 20132, Italy
    Transplant Proc 39:1580-5. 2007
    ..Natriuretic peptides are useful markers for risk stratification of patients with heart disease. However, conflicting results have been reported about circulating atrial natriuretic peptide (ANP) concentration in heart transplant recipients...
  36. ncbi Energy metabolism in diabetic and nondiabetic heart transplant recipients
    Stefano Benedini
    Division of Internal Medicine I, Unit of Clinical Spectroscopy, Istituto Scientifico H San Raffaele, Department of Biomedical Technology, Universita degli Studi di Milano, Milan, Italy
    Diabetes Care 25:530-6. 2002
    ..This study examined the metabolic effects of heart transplantation in patients in end-stage cardiac failure...
  37. ncbi Pathogenesis of obesity and diabetes mellitus: insights provided by indirect calorimetry in humans
    G Perseghin
    Division of Internal Medicine I, Laboratory of Amino Acids and Stable Isotopes, Milan, Italy
    Acta Diabetol 38:7-21. 2001
    ....
  38. ncbi Postabsorptive and insulin-stimulated energy homeostasis and leucine turnover in offspring of type 2 diabetic patients
    Guido Lattuada
    Istituto Scientifico H San Raffaele, Internal Medicine, Section of Nutrition Metabolism and Unit of Clinical Spectroscopy via Olgettina 60, 20132, Milan, Italy
    Diabetes Care 27:2716-22. 2004
    ....
  39. ncbi Cellular mechanism of insulin resistance: potential links with inflammation
    G Perseghin
    Internal Medicine Section of Nutrition Metabolism and Unit of Clinical Spectroscopy, Istituto Scientifico H San Raffaele via Olgettina 60, Milan, Italy
    Int J Obes Relat Metab Disord 27:S6-11. 2003
    ..Understanding these key cellular mechanisms of insulin resistance should help elucidate new targets for treating type 2 diabetes...
  40. ncbi New insights on the simultaneous assessment of insulin sensitivity and beta-cell function with the HOMA2 method
    Andrea Caumo
    Unit of Nutrition and Metabolism, Department of Medicine, San Raffaele Scientific Institute, Via Olgettina, 60, 20132 Milano, Italy
    Diabetes Care 29:2733-4. 2006
  41. ncbi Fasting plasma leptin, tumor necrosis factor-alpha receptor 2, and monocyte chemoattracting protein 1 concentration in a population of glucose-tolerant and glucose-intolerant women: impact on cardiovascular mortality
    Lorenzo Piemonti
    Surgical Department, Istituto Scientifico H San Raffaele, Milan, Italy
    Diabetes Care 26:2883-9. 2003
    ..In vitro studies suggested that these effects may be mediated via overproduction of monocyte chemoattracting protein (MCP)-1/CCL2, which is a chemokine involved in the pathogenesis of atherosclerosis...
  42. ncbi Metabolic effects of restoring partial beta-cell function after islet allotransplantation in type 1 diabetic patients
    L Luzi
    Department of Medicine, Istituto Scientifico H San Raffaele and the University of Milan, Italy
    Diabetes 50:277-82. 2001
    ..The results of the present study indicate that "success" of islet transplantation may be best defined by a number of metabolic criteria, not just glucose concentration/metabolism alone...
  43. doi Delayed-enhanced cardiac MRI for differentiation of Fabry's disease from symmetric hypertrophic cardiomyopathy
    Francesco De Cobelli
    Department of Radiology, San Raffaele Scientific Institute and Vita Salute University, Via Olgettina 60, 20132, Milan, Italy
    AJR Am J Roentgenol 192:W97-102. 2009
    ....
  44. ncbi Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure
    Gabriele Fragasso
    Department of Clinical Cardiology, Heart Failure Clinic, Istituto Scientifico Universita San Raffaele, Via Olgettina 60, 20132 Milano, Italy
    Eur Heart J 27:942-8. 2006
    ....
  45. ncbi Delayed gadolinium-enhanced cardiac magnetic resonance in patients with chronic myocarditis presenting with heart failure or recurrent arrhythmias
    Francesco De Cobelli
    Radiology Department, San Raffaele Scientific Institute and Universita Vita Salute San Raffaele, Milan, Italy
    J Am Coll Cardiol 47:1649-54. 2006
    ..We evaluated the effectiveness of contrast-enhanced cardiac magnetic resonance (CE-CMR) in detecting chronic myocarditis (CM)...
  46. ncbi The anti-ischemic effect of trimetazidine in patients with postprandial myocardial ischemia is unrelated to meal composition
    Gabriele Fragasso
    Heart Failure Unit, Clinical Cardiology, Istituto Scientifico Universita San Raffaele, Milan, Italy
    Am Heart J 151:1238.e1-8. 2006
    ....
  47. ncbi L-arginine-induced vasodilation of the renal vasculature is preserved in uremic type 1 diabetic patients after kidney and pancreas but not after kidney-alone transplantation
    Francesco De Cobelli
    Department of Radiology, Universita Vita e Salute San Raffaele, San Raffaele Scientific Institute, Milan, Italy
    Diabetes Care 27:947-54. 2004
    ..e., curing diabetes, is expected to prevent endothelial damages. Our aim was to study L-arginine-induced vasodilation of the renal vasculature in uremic type 1 diabetic patients after KP or KD using magnetic resonance (MR)...
  48. ncbi Altered kidney graft high-energy phosphate metabolism in kidney-transplanted end-stage renal disease type 1 diabetic patients: a cross-sectional analysis of the effect of kidney alone and kidney-pancreas transplantation
    Paolo Fiorina
    Department of Medicine, San Raffaele Scientific Institute, Via Olgettina 60, Milan 20132, Italy
    Diabetes Care 30:597-603. 2007
    ..The aim of this study was to ascertain the impact of kidney alone (KD) or combined kidney-pancreas (KP) transplantation on renal energy metabolism...
  49. doi MRI of cardiomyopathy
    Elena Belloni
    Department of Radiology, Vita Salute University, San Raffaele Scientific Institute, Via Olgettina, 60, 20132, Milan, Italy
    AJR Am J Roentgenol 191:1702-10. 2008
    ..The aims of this article are to present the main features of MRI of cardiomyopathy and to show selected images of cardiomyopathies...
  50. ncbi Intramyocellular lipid accumulation and reduced whole body lipid oxidation in HIV lipodystrophy
    Livio Luzi
    International Center for Assessment of the Nutritional Status and Clinical Research Unit II, Universita degli Studi di Milano, 20132 Milan, Italy
    Am J Physiol Endocrinol Metab 284:E274-80. 2003
    ..09 mg x kg(-1) x min(-1); P < 0.01). In conclusion, lipodystrophy in HIV-1 patients in antiretroviral treatment is associated with intramuscular fat accumulation, which may mediate the development of the insulin resistance syndrome...
  51. doi Beta cell function during rapamycin monotherapy in long-term type 1 diabetes
    L Piemonti
    Diabetes Research Institute HSR DRI, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    Diabetologia 54:433-9. 2011
    ..We therefore sought to determine whether immunosuppression therapy can reinstate beta cell function in patients with long-term type 1 diabetes...
  52. ncbi Effects of atazanavir/ritonavir and lopinavir/ritonavir on glucose uptake and insulin sensitivity
    Andrea Caumo
    AIDS 21:2366-7. 2007