Jorge Perez

Summary

Affiliation: San Raffaele Scientific Institute
Country: Italy

Publications

  1. ncbi Altered cAMP-dependent protein kinase A in platelets of patients with obsessive-compulsive disorder
    J Perez
    Istituto Scientifico H San Raffaele, Department of Neuropsychiatric Sciences, Milan, Italy
    Am J Psychiatry 157:284-6. 2000
  2. ncbi Altered Rap1 endogenous phosphorylation and levels in platelets from patients with bipolar disorder
    J Perez
    Istituto Scientifico HSR, Department of Neuropsychiatric Sciences, School of Medicine, University of Milan, Italy
    J Psychiatr Res 34:99-104. 2000
  3. ncbi Protein kinase A and Rap1 levels in platelets of untreated patients with major depression
    J Perez
    Istituto Scientifico H San Raffaele, Department of Neuropsychiatric Sciences, School of Medicine, University of Milan, Via Stamira d Ancona 20, 20127 Milan, Italy
    Mol Psychiatry 6:44-9. 2001
  4. ncbi cAMP signaling pathway in depressed patients with psychotic features
    J Perez
    Istituto Scientifico HSR, Department of Neuropsychiatry, School of Medicine, University Vita Salute, Milan, Italy
    Mol Psychiatry 7:208-12. 2002
  5. ncbi [Implications of cAMP signaling in affective disorders]
    J Perez
    Istituto Scientifico H San Raffaele, Department of Neuropsychiatric Siciences, School of Medicine, Universita Vita e Salute, Milan, Italy
    Vertex 12:21-6. 2001
  6. ncbi The interface between depression and cerebrovascular disease--some hope but no hype
    Jorge Perez
    Istituto Scientifico H San Raffaele, Department of Neuropsychiatry, School of Medicine, Universita Vita Salute, via Stamira D Ancona, Milan, Italy
    Clin Exp Hypertens 24:639-46. 2002
  7. ncbi Protein kinase A activity in platelets from patients with bipolar disorder
    Daniela Tardito
    Center of Neuropharmacology, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    J Affect Disord 76:249-53. 2003
  8. ncbi Corticostriatal brain-derived neurotrophic factor dysregulation in adult rats following prenatal stress
    Fabio Fumagalli
    Center of Neuropharmacology, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133, Italy
    Eur J Neurosci 20:1348-54. 2004
  9. ncbi The protein kinase A in platelets from patients with panic disorder
    Daniela Tardito
    Center of Neuropharmacology, Department of Pharmacological Sciences, University of Milan, Milan, Italy
    Eur Neuropsychopharmacol 12:483-7. 2002
  10. ncbi Changes in signaling pathways regulating neuroplasticity induced by neurokinin 1 receptor knockout
    Laura Musazzi
    Center of Neuropharmacology Department of Pharmacological Sciences and Center of Excellence on Neurodegenerative Diseases, University of Milan, Via Balzaretti 9 20133 Milano, Italy
    Eur J Neurosci 21:1370-8. 2005

Collaborators

Detail Information

Publications11

  1. ncbi Altered cAMP-dependent protein kinase A in platelets of patients with obsessive-compulsive disorder
    J Perez
    Istituto Scientifico H San Raffaele, Department of Neuropsychiatric Sciences, Milan, Italy
    Am J Psychiatry 157:284-6. 2000
    ..The purpose of this study was to assess cAMP-dependent protein kinase A in patients with obsessive-compulsive disorder (OCD)...
  2. ncbi Altered Rap1 endogenous phosphorylation and levels in platelets from patients with bipolar disorder
    J Perez
    Istituto Scientifico HSR, Department of Neuropsychiatric Sciences, School of Medicine, University of Milan, Italy
    J Psychiatr Res 34:99-104. 2000
    ..Taken together the results of the present study further support that downstream components of the cAMP signal cascade could be involved in the pathophysiology of bipolar disorders...
  3. ncbi Protein kinase A and Rap1 levels in platelets of untreated patients with major depression
    J Perez
    Istituto Scientifico H San Raffaele, Department of Neuropsychiatric Sciences, School of Medicine, University of Milan, Via Stamira d Ancona 20, 20127 Milan, Italy
    Mol Psychiatry 6:44-9. 2001
    ..These findings may provide new insight about the relationship between components of cAMP signaling and affective disorders...
  4. ncbi cAMP signaling pathway in depressed patients with psychotic features
    J Perez
    Istituto Scientifico HSR, Department of Neuropsychiatry, School of Medicine, University Vita Salute, Milan, Italy
    Mol Psychiatry 7:208-12. 2002
    ..These findings support the idea that besides nonpsychotic depression, abnormalities of PKA could be linked, albeit in a somewhat different way, with psychotic depression...
  5. ncbi [Implications of cAMP signaling in affective disorders]
    J Perez
    Istituto Scientifico H San Raffaele, Department of Neuropsychiatric Siciences, School of Medicine, Universita Vita e Salute, Milan, Italy
    Vertex 12:21-6. 2001
    ..This framework has the potential to improve our knowledge providing clues for the development of novel research strategies in the field of affective disorders...
  6. ncbi The interface between depression and cerebrovascular disease--some hope but no hype
    Jorge Perez
    Istituto Scientifico H San Raffaele, Department of Neuropsychiatry, School of Medicine, Universita Vita Salute, via Stamira D Ancona, Milan, Italy
    Clin Exp Hypertens 24:639-46. 2002
    ....
  7. ncbi Protein kinase A activity in platelets from patients with bipolar disorder
    Daniela Tardito
    Center of Neuropharmacology, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, Italy
    J Affect Disord 76:249-53. 2003
    ..Since altered levels are generally accompanied by functional modifications, the purpose of this study was to investigate PKA activity in patients with BD...
  8. ncbi Corticostriatal brain-derived neurotrophic factor dysregulation in adult rats following prenatal stress
    Fabio Fumagalli
    Center of Neuropharmacology, Department of Pharmacological Sciences, University of Milan, Via Balzaretti 9, 20133, Italy
    Eur J Neurosci 20:1348-54. 2004
    ..The dysregulation of corticostriatal BDNF expression might thus contribute to permanent alterations in brain functions leading to heightened susceptibility to psychiatric disorders...
  9. ncbi The protein kinase A in platelets from patients with panic disorder
    Daniela Tardito
    Center of Neuropharmacology, Department of Pharmacological Sciences, University of Milan, Milan, Italy
    Eur Neuropsychopharmacol 12:483-7. 2002
    ..No significant differences were found in the immunolabelling of Rap1 between groups. These findings may provide clues toward understanding the involvement of cAMP signalling in anxiety disorders...
  10. ncbi Changes in signaling pathways regulating neuroplasticity induced by neurokinin 1 receptor knockout
    Laura Musazzi
    Center of Neuropharmacology Department of Pharmacological Sciences and Center of Excellence on Neurodegenerative Diseases, University of Milan, Via Balzaretti 9 20133 Milano, Italy
    Eur J Neurosci 21:1370-8. 2005
    ..These results show similarities between NK-1 knockouts and animals chronically treated with antidepressants and support the putative antidepressant activity of NK-1 receptor antagonists...
  11. ncbi Dopaminergic D2 receptor activation modulates FGF-2 gene expression in rat prefrontal cortex and hippocampus
    Fabio Fumagalli
    Center of Neuropharmacology, Center of Excellence for Neurodegenerative Diseases, Department of Pharmacological Sciences University of Milan, Milan, Italy
    J Neurosci Res 74:74-80. 2003
    ..Our data highlight the complex modulation of FGF-2 expression in limbic areas pointing to this trophic molecule as a putative target of drugs used against acute and chronic neurodegenerative diseases such as Parkinson's disease...