Flavio Nobili

Summary

Affiliation: San Martino University Hospital
Country: Italy

Publications

  1. ncbi request reprint Resting SPECT-neuropsychology correlation in very mild Alzheimer's disease
    Flavio Nobili
    Section of Clinical Neurophysiology DISEM, Department of Endocrinological and Metabolic Sciences, University of Genoa, Viale Benedetto XV, 6, I 16132 Genoa, Italy
    Clin Neurophysiol 116:364-75. 2005
  2. doi request reprint Cognitive-nigrostriatal relationships in de novo, drug-naïve Parkinson's disease patients: a [I-123]FP-CIT SPECT study
    Flavio Nobili
    Department of Neurosciences, Ophthalmology and Genetics, Clinical Neurophysiology Unit, University of Genoa, Genoa 516132, Italy
    Mov Disord 25:35-43. 2010
  3. pmc No difference in striatal dopamine transporter availability between active smokers, ex-smokers and non-smokers using [123I]FP-CIT (DaTSCAN) and SPECT
    Gerda Thomsen
    Neurobiology Research Unit 9201, Rigshospitalet and Copenhagen University Hospital, Blegdamsvej 9, Copenhagen 2100, Denmark
    EJNMMI Res 3:39. 2013
  4. doi request reprint Radionuclide brain imaging correlates of cognitive impairment in Parkinson's disease (PD)
    Flavio Nobili
    Clinical Neurophysiology, Dept of Neurosciences, Ophthalmology and Genetics, University of Genoa, Genoa, Italy
    J Neurol Sci 310:31-5. 2011
  5. doi request reprint Unawareness of memory deficit in amnestic MCI: FDG-PET findings
    Flavio Nobili
    Clinical Neurophysiology Unit, Dept of Neurosciences, Ophthalmology and Genetics University of Genoa, Genoa, Italy
    J Alzheimers Dis 22:993-1003. 2010
  6. doi request reprint Brain perfusion correlates of cognitive and nigrostriatal functions in de novo Parkinson's disease
    Flavio Nobili
    Clinical Neurophysiology, Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Via De Toni, 5, 16132 Genoa, Italy
    Eur J Nucl Med Mol Imaging 38:2209-18. 2011
  7. doi request reprint Brain SPECT in subtypes of mild cognitive impairment. Findings from the DESCRIPA multicenter study
    Flavio Nobili
    Clinical Neurophysiology Unit, Dept of Endocrinological and Medical Sciences, University of Genoa, Viale Benedetto XV, 6, 16132, Genoa, Italy
    J Neurol 255:1344-53. 2008
  8. doi request reprint Amnestic mild cognitive impairment in Parkinson's disease: a brain perfusion SPECT study
    Flavio Nobili
    Clinical Neurophysiology DISEM, DipTeC, University of Genoa, Genoa, Italy
    Mov Disord 24:414-21. 2009
  9. doi request reprint Principal component analysis of FDG PET in amnestic MCI
    Flavio Nobili
    Clinical Neurophysiology, Department of Endocrinological and Medical Sciences, University of Genoa, Genoa, Italy
    Eur J Nucl Med Mol Imaging 35:2191-202. 2008
  10. ncbi request reprint 99mTc-HMPAO and 99mTc-ECD brain uptake correlates of verbal memory in Alzheimer's disease
    F Nobili
    Clinical Neurophysiology, S Martino General Hospital, Genoa, Italy
    Q J Nucl Med Mol Imaging 51:357-63. 2007

Detail Information

Publications61

  1. ncbi request reprint Resting SPECT-neuropsychology correlation in very mild Alzheimer's disease
    Flavio Nobili
    Section of Clinical Neurophysiology DISEM, Department of Endocrinological and Metabolic Sciences, University of Genoa, Viale Benedetto XV, 6, I 16132 Genoa, Italy
    Clin Neurophysiol 116:364-75. 2005
    ....
  2. doi request reprint Cognitive-nigrostriatal relationships in de novo, drug-naïve Parkinson's disease patients: a [I-123]FP-CIT SPECT study
    Flavio Nobili
    Department of Neurosciences, Ophthalmology and Genetics, Clinical Neurophysiology Unit, University of Genoa, Genoa 516132, Italy
    Mov Disord 25:35-43. 2010
    ..The role of these data as predictive features of cognitive decline and eventually dementia remains to be established in longitudinal studies...
  3. pmc No difference in striatal dopamine transporter availability between active smokers, ex-smokers and non-smokers using [123I]FP-CIT (DaTSCAN) and SPECT
    Gerda Thomsen
    Neurobiology Research Unit 9201, Rigshospitalet and Copenhagen University Hospital, Blegdamsvej 9, Copenhagen 2100, Denmark
    EJNMMI Res 3:39. 2013
    ..We used the database to test the hypothesis that striatal DAT availability is changed in active smokers compared to non-smokers and ex-smokers...
  4. doi request reprint Radionuclide brain imaging correlates of cognitive impairment in Parkinson's disease (PD)
    Flavio Nobili
    Clinical Neurophysiology, Dept of Neurosciences, Ophthalmology and Genetics, University of Genoa, Genoa, Italy
    J Neurol Sci 310:31-5. 2011
    ..Brain PET and SPECT have strongly contributed to the understanding of the pathophysiology of cognitive impairment in PD and may serve as probes to monitor the effects of therapeutic interventions...
  5. doi request reprint Unawareness of memory deficit in amnestic MCI: FDG-PET findings
    Flavio Nobili
    Clinical Neurophysiology Unit, Dept of Neurosciences, Ophthalmology and Genetics University of Genoa, Genoa, Italy
    J Alzheimers Dis 22:993-1003. 2010
    ..Patients with low awareness show a more severe hypometabolic pattern, typical of Alzheimer's disease and therefore could be more at risk of developing dementia...
  6. doi request reprint Brain perfusion correlates of cognitive and nigrostriatal functions in de novo Parkinson's disease
    Flavio Nobili
    Clinical Neurophysiology, Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Via De Toni, 5, 16132 Genoa, Italy
    Eur J Nucl Med Mol Imaging 38:2209-18. 2011
    ..Subtle cognitive impairment is recognized in the first stages of Parkinson's disease (PD), including executive, memory and visuospatial dysfunction, but its pathophysiological basis is still debated...
  7. doi request reprint Brain SPECT in subtypes of mild cognitive impairment. Findings from the DESCRIPA multicenter study
    Flavio Nobili
    Clinical Neurophysiology Unit, Dept of Endocrinological and Medical Sciences, University of Genoa, Viale Benedetto XV, 6, 16132, Genoa, Italy
    J Neurol 255:1344-53. 2008
    ..The aMCI group exhibited a pattern that is typical of early Alzheimer's disease, while the naMCI group showed a more anterior pattern of hypoperfusion. Instead, a homogeneous group effect was lacking in SUBJ...
  8. doi request reprint Amnestic mild cognitive impairment in Parkinson's disease: a brain perfusion SPECT study
    Flavio Nobili
    Clinical Neurophysiology DISEM, DipTeC, University of Genoa, Genoa, Italy
    Mov Disord 24:414-21. 2009
    ..The relevance of this pattern in predicting dementia should be evaluated in longitudinal studies...
  9. doi request reprint Principal component analysis of FDG PET in amnestic MCI
    Flavio Nobili
    Clinical Neurophysiology, Department of Endocrinological and Medical Sciences, University of Genoa, Genoa, Italy
    Eur J Nucl Med Mol Imaging 35:2191-202. 2008
    ....
  10. ncbi request reprint 99mTc-HMPAO and 99mTc-ECD brain uptake correlates of verbal memory in Alzheimer's disease
    F Nobili
    Clinical Neurophysiology, S Martino General Hospital, Genoa, Italy
    Q J Nucl Med Mol Imaging 51:357-63. 2007
    ..We investigated the differences between the 2 compounds in research work by assessing correlation between performance on a verbal memory task and cerebral perfusion in 2 matched groups of AD patients...
  11. ncbi request reprint Migraine during systemic lupus erythematosus: findings from brain single photon emission computed tomography
    Flavio Nobili
    Department of Clinical Neurophysiology, Azienda Ospedale Universita S Martino, Viale Benedetto XV 6, I 16132 Genoa, Italy
    J Rheumatol 33:2184-91. 2006
    ..Perfusion single photon emission computed tomography (SPECT) was performed to investigate brain impairment in SLE patients with migraine-like headache either from the period of diagnosis or later in the course of disease...
  12. doi request reprint SPECT predictors of cognitive decline and Alzheimer's disease in mild cognitive impairment
    Flavio Nobili
    Clinical Neurophysiology Unit, Department of Endocrinological and Medical Sciences, University of Genoa, Genoa
    J Alzheimers Dis 17:761-72. 2009
    ..0002). ROC curves for the mean parietal VROI value showed 0.62 sensitivity with 0.70 specificity in separation of S from D+AD (p < 0.0002). Baseline SPECT can support outcome prediction in subjects with MCI...
  13. ncbi request reprint Quantitative EEG and perfusional single photon emission computed tomography correlation during long-term donepezil therapy in Alzheimer's disease
    Guido Rodriguez
    Clinical Neurophysiology, Department of Internal Medicine, University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy
    Clin Neurophysiol 115:39-49. 2004
    ....
  14. ncbi request reprint Brain perfusion follow-up in Alzheimer's patients during treatment with acetylcholinesterase inhibitors
    Flavio Nobili
    Clinical Neurophysiology, Department of Internal Medicine, University of Genoa, Italy
    J Nucl Med 43:983-90. 2002
    ..The aim of this study was to evaluate brain perfusion changes by SPECT in AD patients during chronic AChEI therapy in relation to their cognitive evolution...
  15. doi request reprint Mapping brain morphological and functional conversion patterns in amnestic MCI: a voxel-based MRI and FDG-PET study
    Silvia Morbelli
    Nuclear Medicine Unit, Department of Internal Medicine, University of Genoa, Viale Benedetto XV, 6, 16132 Genoa, Italy
    Eur J Nucl Med Mol Imaging 37:36-45. 2010
    ..To reveal the morphological and functional substrates of memory impairment and conversion to Alzheimer disease (AD) from the stage of amnestic mild cognitive impairment (aMCI)...
  16. doi request reprint What predicts cognitive decline in de novo Parkinson's disease?
    Dario Arnaldi
    Clinical Neurophysiology, Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Italy
    Neurobiol Aging 33:1127.e11-20. 2012
    ..The combined use of clinical structured examination and brain functional assessment by means of dual single photon emission computed tomography imaging appears as a powerful approach to predict cognitive decline in de novo PD patients...
  17. doi request reprint The short cognitive evaluation battery in cognitive disorders of the elderly--Italian version
    Nicola Girtler
    Clinical Neurophysiology, Department of Neuroscience, Ophthalmology and Genetics, IRCCS San Martino IST University Hospital, University of Genoa, Genoa, Italy
    Dement Geriatr Cogn Disord 33:255-65. 2012
    ....
  18. doi request reprint Impaired access to semantic memory for the cognition of geographic space in Alzheimer's disease
    Debora Mazzei
    Clinical Neurophysiology DiNOG, DipTeC, University of Genoa, S Martino University Hospital, Viale Benedetto XV, 6, I 16132 Genoa, Italy
    Arch Gerontol Geriatr 50:198-201. 2010
    ..Besides a reduction of semantic verbal fluency, there seems to be a 'restriction' of mental geographic space representation already in mild AD. These findings should be confirmed and exploited by further ad hoc investigations...
  19. ncbi request reprint Quantitative EEG changes in Alzheimer patients during long-term donepezil therapy
    Guido Rodriguez
    Clinical Neurophysiology, Department of Internal Medicine, University of Genoa, Genoa, Italy
    Neuropsychobiology 46:49-56. 2002
    ..The effect was significant in frontal regions, possibly because they are relatively spared during the mild-to-moderate phases of the disease...
  20. doi request reprint Metabolic networks underlying cognitive reserve in prodromal Alzheimer disease: a European Alzheimer disease consortium project
    Silvia Morbelli
    Nuclear Medicine, Department of Internal Medicine, IRCCS AOU San Martino IST, University of Genoa, Genoa, Italy
    J Nucl Med 54:894-902. 2013
    ..This project aimed to investigate the metabolic basis for resilience to neurodegeneration (cognitive reserve) in highly educated patients with prodromal Alzheimer disease (AD)...
  21. doi request reprint Seizures can precede cognitive symptoms in late-onset Alzheimer's disease
    Agnese Picco
    Clinical Neurophysiology, Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Genoa, Italy
    J Alzheimers Dis 27:737-42. 2011
    ..This case of seizures at onset of LOAD with severe signs of brain amyloidosis and neurodegeneration but with just MCI leads to a re-appraisal of the intriguing relationship between AD pathology and neuron excitability in humans...
  22. doi request reprint Metabolic correlates of Rey auditory verbal learning test in elderly subjects with memory complaints
    Andrea Brugnolo
    Clinical Neurology, Dept of Neuroscience DINOGMI, University of Genoa, Italy
    J Alzheimers Dis 39:103-13. 2014
    ....
  23. doi request reprint Resting metabolic connectivity in prodromal Alzheimer's disease. A European Alzheimer Disease Consortium (EADC) project
    Silvia Morbelli
    Nuclear Medicine Unit, Department of Internal Medicine, San Martino University Hospital, Genoa, Italy
    Neurobiol Aging 33:2533-50. 2012
    ....
  24. doi request reprint Correlation between Doppler velocities and duplex ultrasound carotid cross-sectional percent stenosis
    Guido Rodriguez
    Department of Neurosciences, Ophthalmology and Genetics, Clinical Neurophysiology Unit, University of Genoa, Via De Toni, 5, 16132 Genoa, Italy
    Acad Radiol 18:1485-91. 2011
    ....
  25. ncbi request reprint Right hemispheric dysfunction in a case of pure progressive aphemia: fusion of multimodal neuroimaging
    Paolo Vitali
    Clinical Neurophysiology, Department of Internal Medicine, University of Genoa, Viale Benedetto XV, 10, 16132 Genoa, Italy
    Psychiatry Res 130:97-107. 2004
    ..Results are discussed in terms of bihemispheric language representation. The fusion of three sets of neuroimages has aided in the interpretation of the patient's cognitive brain dysfunction...
  26. ncbi request reprint Cortical sources of awake scalp EEG in eating disorders
    Guido Rodriguez
    Section of Clinical Neurophysiology DISEM, Department of Endocrinological and Metabolic Sciences, University of Genoa, Genoa, Italy
    Clin Neurophysiol 118:1213-22. 2007
    ..To investigate quantitative EEG (qEEG) in anorexia nervosa (AN) and bulimia nervosa (BN) in comparison with healthy controls...
  27. doi request reprint Automatic semi-quantification of [123I]FP-CIT SPECT scans in healthy volunteers using BasGan version 2: results from the ENC-DAT database
    Flavio Nobili
    Clinical Neurophysiology, Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Genoa, Italy
    Eur J Nucl Med Mol Imaging 40:565-73. 2013
    ..The aim of this study was to assess striatal dopamine transporter (DAT) availability in a large group of normal subjects...
  28. ncbi request reprint Effects of long-term Donepezil therapy on rCBF of Alzheimer's patients
    Flavio Nobili
    Clinical Neurophysiology Service, Department of Internal Medicine, University of Genoa, Viale Benedetto XV, 6 I 16132 Genoa, Italy
    Clin Neurophysiol 113:1241-8. 2002
    ....
  29. ncbi request reprint The basal ganglia matching tools package for striatal uptake semi-quantification: description and validation
    Piero Calvini
    Department of Physics, University and INFN, Genoa, Italy
    Eur J Nucl Med Mol Imaging 34:1240-53. 2007
    ..To design a novel algorithm (BasGan) for automatic segmentation of striatal (123)I-FP-CIT SPECT...
  30. doi request reprint Plasma antioxidants and brain glucose metabolism in elderly subjects with cognitive complaints
    Agnese Picco
    Clinical Neurology, Department of Neuroscience DINOGMI, University of Genoa and IRCCS San Martino IST, Largo P Daneo, 3, 16132, Genoa, Italy
    Eur J Nucl Med Mol Imaging 41:764-75. 2014
    ..We hypothesized that oxidative stress could play a role in impairing brain glucose utilization in elderly subjects with increasing severity of cognitive disturbance...
  31. ncbi request reprint The need of appropriate brain SPECT templates for SPM comparisons
    S Morbelli
    Nuclear Medicine Unit, S Martino University, Hospital, Genoa, Italy
    Q J Nucl Med Mol Imaging 52:89-98. 2008
    ....
  32. doi request reprint Traditional and non traditional risk factors in accelerated atherosclerosis in systemic lupus erythematosus: role of vascular endothelial growth factor (VEGATS Study)
    Barbara Maria Colombo
    Department of Internal Medicine, University of Genoa, Italy
    Autoimmun Rev 8:309-15. 2009
    ..To evaluate the role of vascular endothelial growth factor (VEGF) in accelerated atherosclerosis in patients with Systemic Lupus Erythematosus (SLE)...
  33. ncbi request reprint Hippocampal perfusion in mild Alzheimer's disease
    G Rodriguez
    Service of Clinical Neurophysiology, Department of Internal Medicine, University of Genoa, Viale Benedetto XV, 6, I 16132, Genoa, Italy
    Psychiatry Res 100:65-74. 2000
    ....
  34. pmc A repository based on a dynamically extensible data model supporting multidisciplinary research in neuroscience
    Luca Corradi
    University of Genoa, Dept of Computer Science, Bioengineering, Robotics and Systems Engineering, Genoa, Italy
    BMC Med Inform Decis Mak 12:115. 2012
    ....
  35. ncbi request reprint Cognitive impairment in degenerative parkinsonisms: role of radionuclide brain imaging
    D Arnaldi
    Clinical Neurophysiology, Department of Neuroscience, Ophthalmology and Genetics, San Martino University Hospital, Genoa, Italy
    Q J Nucl Med Mol Imaging 56:55-67. 2012
    ....
  36. ncbi request reprint Clinical correlative evaluation of an iterative method for reconstruction of brain SPECT images
    F Nobili
    Services of Clinical Neurophysiology, Department of Internal Medicine, University of Genoa, Viale Benedetto XV, 6, I 16132, Genoa, Italy
    Nucl Med Biol 28:627-32. 2001
    ....
  37. ncbi request reprint The Von Restorff effect in ageing and Alzheimer's disease
    P Vitali
    Clinical Neurophysiology, DI M I, University of Genova, V le Benedetto XV 6, I 16132 Genova, Italy
    Neurol Sci 27:166-72. 2006
    ..On the basis of the findings of the present study it is not possible to disentangle the contribution of visual-perceptual and encoding impairment, both of them potentially contributing to the observed reduction...
  38. ncbi request reprint Brain perfusion spect in juvenile neuro-Behçet's disease
    S Vignola
    II Division of Pediatrics, Giannina Gaslini Institute, University of Genoa, Italy
    J Nucl Med 42:1151-7. 2001
    ....
  39. ncbi request reprint Regional cerebral blood flow and prognostic evaluation in Alzheimer's disease
    F Nobili
    Clinical Neurophysiology Service, Department of Internal Medicine, University of Genoa, Genoa, Italy
    Dement Geriatr Cogn Disord 12:89-97. 2001
    ....
  40. ncbi request reprint Psychological and social aspects in management of Alzheimer's patients: an inquiry among caregivers
    G Rodriguez
    Clinical Neurophysiology, Department of Internal Medicine, University of Genoa, Viale Benedetto XV 6, I 16132 Genoa, Italy
    Neurol Sci 24:329-35. 2003
    ..A strong need for information and support is clearly emerging and any further interventions should take these requirements into consideration...
  41. ncbi request reprint Global cognitive impairment should be taken into account in SPECT-neuropsychology correlations: the example of verbal memory in very mild Alzheimer's disease
    G Rodriguez
    Clinical Neurophysiology, Department of Endocrinological and Metabolic Sciences, University of Genoa, Viale Benedetto XV, 6, 16132, Genoa, Italy
    Eur J Nucl Med Mol Imaging 32:1186-92. 2005
    ....
  42. doi request reprint The reversed clock drawing test phenomenon in Alzheimer's disease: A perfusion SPECT study
    A Brugnolo
    Department of Neuroscience, Ophthalmology and Genetics, University of Genoa, Italy
    Dement Geriatr Cogn Disord 29:1-10. 2010
    ..To unveil a brain single photon emission computed tomography (SPECT) pattern in Alzheimer's disease (AD) patients, showing a reversed clock drawing test (CDT) phenomenon...
  43. doi request reprint The factorial structure of the mini mental state examination (MMSE) in Alzheimer's disease
    A Brugnolo
    Clinical Neurophysiology Unit, Department of Endocrinological and Medical Science, University of Genoa, Viale Benedetto XV 6, I 16132 Genoa, Italy
    Arch Gerontol Geriatr 49:180-5. 2009
    ..The second factor is related with a more consolidated knowledge, namely verbal abilities, and is essentially useless in mild to moderate AD...
  44. ncbi request reprint Sources of cortical rhythms change as a function of cognitive impairment in pathological aging: a multicenter study
    Claudio Babiloni
    Dip Fisiologia Umana e Farmacologia, Univ La Sapienza Rome, Italy
    Clin Neurophysiol 117:252-68. 2006
    ..change across normal elderly (Nold), mild cognitive impairment (MCI), and Alzheimer's disease (AD) subjects as a function of the global cognitive level...
  45. ncbi request reprint Resting EEG sources correlate with attentional span in mild cognitive impairment and Alzheimer's disease
    Claudio Babiloni
    Dip Fisiologia Umana e Farmacologia, Universita degli Studi di Roma La Sapienza, P le Aldo Moro 5, 00185 Rome, Italy
    Eur J Neurosci 25:3742-57. 2007
    ..05). These results suggest that cortical sources of resting delta and alpha rhythms correlate with neuropsychological measures of immediate memory based on focused attention in the continuum of MCI and AD subjects...
  46. ncbi request reprint Frontal white matter volume and delta EEG sources negatively correlate in awake subjects with mild cognitive impairment and Alzheimer's disease
    Claudio Babiloni
    Dipartimento di Fisiologia Umana e Farmacologia, University La Sapienza, Rome, Italy
    Clin Neurophysiol 117:1113-29. 2006
    ..Am J Neuroradiol. 2003 24(3):481-487]. In this study, we tested the hypothesis that such a relationship does exist not only in AD patients but also across the continuum of subjects with mild cognitive impairment (MCI) and AD...
  47. ncbi request reprint 99mTc-HMPAO and 99mTc-ECD perform differently in typically hypoperfused areas in Alzheimer's disease
    Pierre Malick Koulibaly
    Nuclear Medicine Department, Centre Antoine Lacassagne, University of Nice Sophia Antipolis, France
    Eur J Nucl Med Mol Imaging 30:1009-13. 2003
    ..These differences confirm the need for specific normal databases, but their impact on routine SPET reports in AD is not known and deserves an ad hoc investigation...
  48. ncbi request reprint Identification by [99mTc]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease
    Andrea Varrone
    Biostructure and Bioimaging Institute, National Research Council Department of Biomorphological and Functional Sciences, University Federico II, Napoli, Italy
    Eur J Nucl Med Mol Imaging 34:1071-81. 2007
    ....
  49. ncbi request reprint Abnormal fronto-parietal coupling of brain rhythms in mild Alzheimer's disease: a multicentric EEG study
    Claudio Babiloni
    Dip Fisiologia Umana e Farmacologia, University La Sapienza Rome, Italy
    Eur J Neurosci 19:2583-90. 2004
    ..These results suggest that mild AD is characterized by an abnormal fronto-parietal coupling of the dominant human cortical rhythm at 8-10.5 Hz...
  50. ncbi request reprint Grouping for behavioral and psychological symptoms in dementia: clinical and biological aspects. Consensus paper of the European Alzheimer disease consortium
    Philippe H Robert
    Centre Mémoire de Ressources and de Recherche, CHU, Hopital Pasteur, Universite de Nice Sophia Antipolis, 30, avenue de la Voie Romaine, 06002 Nice cedex 1, France
    Eur Psychiatry 20:490-6. 2005
    ..An individually tailored approach taking all these aspects into account is warranted as it may offer more, and better, pharmacological and non-pharmacological treatment opportunities...
  51. ncbi request reprint Neuropsychiatric syndromes in dementia. Results from the European Alzheimer Disease Consortium: part I
    Pauline Aalten
    Department of Psychiatry and Neuropsychology, Alzheimer Centre Limburg, Maastricht University Hospital, Maastricht, The Netherlands
    Dement Geriatr Cogn Disord 24:457-63. 2007
    ..The aim of this study was to identify neuropsychiatric subsyndromes of the Neuropsychiatric Inventory in a large sample of outpatients with Alzheimer's disease (AD)...
  52. ncbi request reprint Consistency of neuropsychiatric syndromes across dementias: results from the European Alzheimer Disease Consortium. Part II
    Pauline Aalten
    Department of Psychiatry and Neuropsychology, Alzheimer Centre Limburg, Maastricht University Hospital, Maastricht, The Netherlands
    Dement Geriatr Cogn Disord 25:1-8. 2008
    ..g. dementia subtypes, dementia severity, medication use, age and gender) in a large sample of outpatients with dementia...
  53. ncbi request reprint Mitochondrial function is related to alterations at brain SPECT in depressed patients
    Ann Gardner
    Division of Psychiatry, Department of Clinical Neuroscience, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    CNS Spectr 13:805-14. 2008
    ....
  54. ncbi request reprint Sources of cortical rhythms in adults during physiological aging: a multicentric EEG study
    Claudio Babiloni
    Dipartimento di Fisiologia Umana e Farmacologia, Universita La Sapienza, Rome, Italy
    Hum Brain Mapp 27:162-72. 2006
    ..In conclusion, this new methodological approach holds promise for the prediction of dementia in mild cognitive impairment by regional source rather than surface EEG data and by both linear and nonlinear predictors...
  55. ncbi request reprint Fronto-parietal coupling of brain rhythms in mild cognitive impairment: a multicentric EEG study
    Claudio Babiloni
    Dipartimento di Fisiologia Umana e Farmacologia, Universita degli Studi di Roma La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy
    Brain Res Bull 69:63-73. 2006
    ..Future longitudinal research should evaluate whether the present EEG approach is able to predict the cognitive decline in individual MCI subjects...
  56. ncbi request reprint Statistical parametric mapping of (99m)Tc-HMPAO-SPECT images for the diagnosis of Alzheimer's disease: normalizing to cerebellar tracer uptake
    Darius Soonawala
    Department of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, United Kingdom
    Neuroimage 17:1193-202. 2002
    ..We also investigated whether cerebellar normalization increases the sensitivity and specificity of SPM analysis of ATD patients compared with global normalization...
  57. ncbi request reprint Donepezil effects on sources of cortical rhythms in mild Alzheimer's disease: Responders vs. Non-Responders
    Claudio Babiloni
    Dip Fisiologia Umana e Farmacologia, Univ La Sapienza, Rome, Italy
    Neuroimage 31:1650-65. 2006
    ..Donepezil could act by reactivating existing yet functionally silent cortical synapses in Responders, restoring temporal and occipital alpha rhythms...
  58. ncbi request reprint Predicting the accuracy of a diagnosis of Alzheimer's disease with 99mTc HMPAO single photon emission computed tomography
    Nadine Dougall
    Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Edinburgh EH105HF, Scotland, UK
    Psychiatry Res 131:157-68. 2004
    ..Using multiple raters in large patient samples may provide a way of identifying successful explicit diagnostic strategies for clinical image analysis...
  59. ncbi request reprint Quality of life and brain function following high-dose recombinant human erythropoietin in low-risk myelodysplastic syndromes: a preliminary report
    Marino Clavio
    Department of Haematology and Oncology, Azienda Ospedale S Martino e Cliniche Universitaire Convenzionate, Genova, Italy
    Eur J Haematol 72:113-20. 2004
    ..Preliminary data are reported...
  60. ncbi request reprint Mapping distributed sources of cortical rhythms in mild Alzheimer's disease. A multicentric EEG study
    Claudio Babiloni
    Dipartimento di Fisiologia Umana e Farmacologia, Sezione di EEG ad Alta Risoluzione, Universita degli Studi di Roma La Sapienza, Rome, Italy
    Neuroimage 22:57-67. 2004
    ..Future studies should evaluate the clinical usefulness of this approach in early differential diagnosis, disease staging, and therapy monitoring...
  61. ncbi request reprint Individual analysis of EEG frequency and band power in mild Alzheimer's disease
    Davide V Moretti
    Dipartimento Fisiologia Umana e Farmacologia, Universita degli Studi di Roma La Sapienza, P le Aldo Moro 5, 00185 Rome, Italy
    Clin Neurophysiol 115:299-308. 2004
    ..This EEG study investigates the role of the cholinergic system, cortico-cortical connections, and sub-cortical white matter on the relationship between individual EEG frequencies and their relative power bands...