L Leocani

Summary

Affiliation: San Raffaele Scientific Institute
Country: Italy

Publications

  1. ncbi Movement preparation is affected by tissue damage in multiple sclerosis: evidence from EEG event-related desynchronization
    L Leocani
    Department of Neurology, Clinical Neurophysiology and Neurorehabilitation, Scientific Institute, Hospital San Raffaele, University Vita Salute, Via Olgettina 60, 20132 Milan, Italy
    Clin Neurophysiol 116:1515-9. 2005
  2. ncbi Computational classifiers for predicting the short-term course of Multiple sclerosis
    Bartolome Bejarano
    Department of Neuroscience, CIMA University of Navarra, Pamplona, Spain
    BMC Neurol 11:67. 2011
  3. ncbi Multimodal evoked potentials to assess the evolution of multiple sclerosis: a longitudinal study
    L Leocani
    Department of Neurology, Clinical Neurophysiology and Neurorehabilitation, Scientific Institute Hospital San Raffaele, University Vita Salute, Milan, Italy
    J Neurol Neurosurg Psychiatry 77:1030-5. 2006
  4. ncbi Impaired short-term motor learning in multiple sclerosis: evidence from virtual reality
    Letizia Leocani
    Department of Neurology, Clinical Neurophysiology and Neurorehabilitation, University Vita Salute, Scientific Institute Hospital San Raffaele, Milan, Italy
    Neurorehabil Neural Repair 21:273-8. 2007
  5. ncbi Fatigue in multiple sclerosis is associated with abnormal cortical activation to voluntary movement--EEG evidence
    L Leocani
    Department of Neurophysiology, Scientific Institute H. San Raffaele, Milan, Italy
    Neuroimage 13:1186-92. 2001
  6. ncbi Cortical activation to voluntary movement in amyotrophic lateral sclerosis is related to corticospinal damage: electrophysiological evidence
    N Riva
    Scientific Institute and Vita Salute University San Raffaele, INSPE Department of Neurology, Milan, Italy
    Clin Neurophysiol 123:1586-92. 2012
  7. ncbi Cortical function abnormalities in migraine: neurophysiological and neuropsychological evidence from reaction times and event-related potentials to the Stroop test
    P Annovazzi
    Department of Neurology, I.R.C.C.S. San Raffaele, Via Olgettina 48, I-20132 Milan, Italy
    Neurol Sci 25:S285-7. 2004
  8. ncbi Clinical and MRI assessment of brain damage in MS
    G Comi
    Department of Neuroscience, Scientific Institute H San Raffaele, Milan, Italy
    Neurol Sci 22:S123-7. 2001
  9. ncbi Assessment of the damage of the cerebral hemispheres in MS using neuroimaging techniques
    G Comi
    Department of Neuroscience, Scientific Institute Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy
    J Neurol Sci 172:S63-6. 2000
  10. ncbi A multiparametric MRI study of frontal lobe dementia in multiple sclerosis
    G Comi
    Clinical Trials Unit, Department of Neuroscience, Scientific Institute H San Raffaele, Via Olgettina 60, 20132, Milan, Italy
    J Neurol Sci 171:135-44. 1999

Collaborators

Detail Information

Publications27

  1. ncbi Movement preparation is affected by tissue damage in multiple sclerosis: evidence from EEG event-related desynchronization
    L Leocani
    Department of Neurology, Clinical Neurophysiology and Neurorehabilitation, Scientific Institute, Hospital San Raffaele, University Vita Salute, Via Olgettina 60, 20132 Milan, Italy
    Clin Neurophysiol 116:1515-9. 2005
    ..To investigate the impact of brain tissue damage in Multiple Sclerosis (MS) on the efficiency of programming of voluntary movement, assessed using event-related desynchronization of the EEG...
  2. ncbi Computational classifiers for predicting the short-term course of Multiple sclerosis
    Bartolome Bejarano
    Department of Neuroscience, CIMA University of Navarra, Pamplona, Spain
    BMC Neurol 11:67. 2011
    ..The aim of this study was to assess the diagnostic accuracy (sensitivity and specificity) of clinical, imaging and motor evoked potentials (MEP) for predicting the short-term prognosis of multiple sclerosis (MS)...
  3. ncbi Multimodal evoked potentials to assess the evolution of multiple sclerosis: a longitudinal study
    L Leocani
    Department of Neurology, Clinical Neurophysiology and Neurorehabilitation, Scientific Institute Hospital San Raffaele, University Vita Salute, Milan, Italy
    J Neurol Neurosurg Psychiatry 77:1030-5. 2006
    ..Evoked potentials are used in the functional assessment of sensory and motor pathways. Their usefulness in monitoring the evolution of multiple sclerosis has not been fully clarified...
  4. ncbi Impaired short-term motor learning in multiple sclerosis: evidence from virtual reality
    Letizia Leocani
    Department of Neurology, Clinical Neurophysiology and Neurorehabilitation, University Vita Salute, Scientific Institute Hospital San Raffaele, Milan, Italy
    Neurorehabil Neural Repair 21:273-8. 2007
    ..The objective of this study was to investigate the usefulness of VR in the assessment of short-term motor learning in multiple sclerosis (MS)...
  5. ncbi Fatigue in multiple sclerosis is associated with abnormal cortical activation to voluntary movement--EEG evidence
    L Leocani
    Department of Neurophysiology, Scientific Institute H. San Raffaele, Milan, Italy
    Neuroimage 13:1186-92. 2001
    ....
  6. ncbi Cortical activation to voluntary movement in amyotrophic lateral sclerosis is related to corticospinal damage: electrophysiological evidence
    N Riva
    Scientific Institute and Vita Salute University San Raffaele, INSPE Department of Neurology, Milan, Italy
    Clin Neurophysiol 123:1586-92. 2012
    ..We investigated ERD and ERS in amyotrophic lateral sclerosis (ALS) patients and the relationship with anatomical and neurophysiological measures of corticospinal tract damage...
  7. ncbi Cortical function abnormalities in migraine: neurophysiological and neuropsychological evidence from reaction times and event-related potentials to the Stroop test
    P Annovazzi
    Department of Neurology, I.R.C.C.S. San Raffaele, Via Olgettina 48, I-20132 Milan, Italy
    Neurol Sci 25:S285-7. 2004
    ..We found a slower RTs in patients if compared to controls, supporting the hypothesis of a mild cortical functions impairment even in interictal periods in this group of patients...
  8. ncbi Clinical and MRI assessment of brain damage in MS
    G Comi
    Department of Neuroscience, Scientific Institute H San Raffaele, Milan, Italy
    Neurol Sci 22:S123-7. 2001
    ..Other factors, such as the site of MS lesions and the presence of active inflammation, also seem to play an important role...
  9. ncbi Assessment of the damage of the cerebral hemispheres in MS using neuroimaging techniques
    G Comi
    Department of Neuroscience, Scientific Institute Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy
    J Neurol Sci 172:S63-6. 2000
    ..Other factors, such as the site of MS lesions and the presence of active inflammation, also seem to play an important role...
  10. ncbi A multiparametric MRI study of frontal lobe dementia in multiple sclerosis
    G Comi
    Clinical Trials Unit, Department of Neuroscience, Scientific Institute H San Raffaele, Via Olgettina 60, 20132, Milan, Italy
    J Neurol Sci 171:135-44. 1999
    ..Cerebellar MTR histogram metrics did not significantly differ in patients with and without cognitive decline. The presence of cognitive decline in MS is associated with the extent and pathological severity of brain MRI abnormalities...
  11. ncbi Physiopathology and treatment of fatigue in multiple sclerosis
    G Comi
    University of Milan, Department of Neuroscience, Scientific Institute H San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    J Neurol 248:174-9. 2001
    ..No specific treatments are available. Management strategies include medications, exercise, and behavioural therapy; in most cases a combined approach is appropriate...
  12. ncbi Abnormal pattern of cortical activation associated with voluntary movement in obsessive-compulsive disorder: an EEG study
    L Leocani
    Departments of Neurophysiology and Psychiatry, Scientific Institute, Hospital San Raffaele, Milan, Italy
    Am J Psychiatry 158:140-2. 2001
    ..The authors investigated the circuits involved in motor behavior in OCD by using event-related desynchronization/synchronization...
  13. ncbi Changes in brain glucose metabolism in subthalamic nucleus deep brain stimulation for advanced Parkinson's disease
    M A Volonte
    Department of Neurology, INSPE, San Raffaele Scientific Institute, Via Olgettina 48, I 20132 Milan, Italy
    Parkinsonism Relat Disord 18:770-4. 2012
    ....
  14. ncbi Treatment of Wernicke's encephalopathy with high dose of thiamine in a patient with pyloric sub-stenosis: description of a case
    Francesca Caso
    Department of Neurology, San Raffaele Scientific Institute, Via Olgettina 48, Milan, Italy
    Neurol Sci 31:859-61. 2010
    ....
  15. ncbi Flash visual evoked potentials in mice can be modulated by transcranial direct current stimulation
    M Cambiaghi
    San Raffaele Scientific Institute, Vita Salute San Raffaele University, Institute of Experimental Neurology INSPE, Experimental Neurophysiology Unit, Milan, Italy
    Neuroscience 185:161-5. 2011
    ....
  16. ncbi Acute effects of L-dopa on event-related desynchronization in Parkinson's disease
    G Magnani
    Department of Clinical Neurophysiology, San Raffaele Scientific Institute, Milan, Italy
    Neurol Sci 23:91-7. 2002
    ..We conclude that a single dose of dispersible L-dopa can improve not only motor performance in IPD patients but also the timing of cortical activation of sensorimotor areas during motor programming...
  17. ncbi Neurophysiological investigations in multiple sclerosis
    L Leocani
    Neurophysiology Department, Scientific Institute Hosptial San Raffaele, Milan, Italy
    Curr Opin Neurol 13:255-61. 2000
    ....
  18. ncbi Action-related semantic content and negation polarity modulate motor areas during sentence reading: an event-related desynchronization study
    F Alemanno
    Scientific Institute Hospital San Raffaele, Experimental Neurophysiology Unit Institute of Experimental Neurologi INSPE, Via Olgettina 60, 20132 Milan, Italy
    Brain Res 1484:39-49. 2012
    ..In addition, motor cortex activation was larger for negative than affirmative motor sentences, a finding compatible with the hypothesis that comprehension is more demanding in the specific case of motor content negation...
  19. ncbi Electrophysiological studies of brain plasticity of the motor system
    L Leocani
    Department of Neurology, Clinical Neurophysiology and Rehabilitation Scientific Institute, University Hospital San Raffaele, Via Olgettina 60, I 20132 Milan, Italy
    Neurol Sci 27:S27-9. 2006
    ..We will focus on the main applications of these techniques, mainly electroencephalography and transcranial magnetic stimulation, in the study of brain plasticity in humans following motor learning or lesions of the nervous system...
  20. ncbi Review neuroimaging in amyotrophic lateral sclerosis
    G Comi
    Department of Neurophysiopathology, Scientific Institute Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy
    Eur J Neurol 6:629-37. 1999
    ....
  21. ncbi Sporadic failure of botulinum toxin treatment in usually responsive patients with adductor spasmodic dysphonia
    G Galardi
    Clinical Neurophysiology, Department of Neuroscience, Scientific Institute Hospital San Raffaele, Milan, Italy
    Neurol Sci 22:303-6. 2001
    ..These data suggest that treatment failure may occur regardless of the method of injection and of the drug preparation used, possibly due to mislocalisation of vocal folds...
  22. ncbi Movement-related event-related desynchronization in neuropsychiatric disorders
    Letizia Leocani
    Department of Neurology, Clinical Neurophysiology and Neurorehabilitation, University Vita Salute, Scientific Institute Hospital San Raffaele, Milan, Italy
    Prog Brain Res 159:351-66. 2006
    ..Further studies are needed in order to validate the usefulness of this methodology in the assessment of the single patient for diagnosis and monitoring of the natural course of the disease and of treatment efficacy...
  23. ncbi Somatosensory evoked potentials and sensory involvement in multiple sclerosis: comparison with clinical findings and quantitative sensory tests
    Letizia Leocani
    Department of Clinical Neurophysiology, University Vita Salute, Scientific Institute Hospital San Raffaele, Milan, Italy
    Mult Scler 9:275-9. 2003
    ..Moreover QSTs are to be preferred to clinical evaluation in the assessment of thermal sense, due to their superior sensitivity...
  24. ncbi Demyelination and cortical reorganization: functional MRI data from a case of subacute combined degeneration
    Massimo Filippi
    Neuroimaging Research Unit, Department of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    Neuroimage 18:558-63. 2003
    ..This multiparametric magnetic resonance study of a patient with an early diagnosis of subacute combined degeneration suggests that demyelination alone does not necessarily induce adaptive functional changes of the cerebral cortex...
  25. ncbi Botulinum toxin type B vs. type A in toxin-naïve patients with cervical dystonia: Randomized, double-blind, noninferiority trial
    Eric J Pappert
    Solstice Neurosciences, Inc, Malvern, Pennsylvania, USA
    Mov Disord 23:510-7. 2008
    ..Mild dry mouth was more frequent with BoNT-B but there were no differences for moderate/severe dry mouth. In this study, both BoNT-A and B were shown to be effective and safe for the treatment of toxin-naive CD subjects...
  26. ncbi Persistence of congenital mirror movements after hemiplegic stroke
    Maria A Rocca
    Neuroimaging Research Unit, Department of Neurology, Scientific Institute and University Ospedale San Raffaele, Milan, Italy
    AJNR Am J Neuroradiol 26:831-4. 2005
    ..Both these mechanisms are likely to be involved in the genesis of MMs...
  27. ncbi Visual evoked potentials may be recorded simultaneously with fMRI scanning: A validation study
    Eleonora Comi
    Department of Neurology and Clinical Neurophysiology, University Vita-Salute, Scientific Institute Hospital San Raffaele, Milan, Italy
    Hum Brain Mapp 24:291-8. 2005
    ..This possibility might be helpful by shortening recording times and reducing variability from learning, habituation, and fatigue phenomena from separate recordings for the integration of event-related EEG and fMRI data...