Giovanni Landoni

Summary

Affiliation: San Raffaele Scientific Institute
Country: Italy

Publications

  1. ncbi request reprint Volatile anesthetics for periprocedural cardiac protection. A review
    G Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Vita Salute San Raffaele University, Milan, Italy
    Minerva Cardioangiol 56:429-34. 2008
  2. ncbi request reprint Effects of levosimendan on mortality and hospitalization. A meta-analysis of randomized controlled studies
    Giovanni Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italy
    Crit Care Med 40:634-46. 2012
  3. pmc Dexmedetomidine as a sedative agent in critically ill patients: a meta-analysis of randomized controlled trials
    Laura Pasin
    Anesthesia and Intensive Care Department, San Raffaele Scientific Institute, Milan, Italy
    PLoS ONE 8:e82913. 2013
  4. pmc Bystander-initiated chest compression-only CPR is better than standard CPR in out-of-hospital cardiac arrest
    L Cabrini
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    HSR Proc Intensive Care Cardiovasc Anesth 2:279-85. 2010
  5. pmc Fenoldopam to prevent renal replacement therapy after cardiac surgery. Design of the FENO-HSR study
    G Landoni
    Universita Vita Salute San Raffaele, Milano
    HSR Proc Intensive Care Cardiovasc Anesth 2:111-7. 2010
  6. pmc Mortality reduction in cardiac anesthesia and intensive care: results of the first International Consensus Conference
    G Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    HSR Proc Intensive Care Cardiovasc Anesth 3:9-19. 2011
  7. pmc A new method for managing emergency calls
    G Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    HSR Proc Intensive Care Cardiovasc Anesth 2:35-9. 2010
  8. pmc Percutaneous aortic valve implantation: the anesthesiologist perspective
    R D Covello
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    HSR Proc Intensive Care Cardiovasc Anesth 1:28-38. 2009
  9. pmc Cardiac protection by volatile anesthetics in non-cardiac surgery? A meta-analysis of randomized controlled studies on clinically relevant endpoints
    G Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    HSR Proc Intensive Care Cardiovasc Anesth 1:34-43. 2009
  10. pmc Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial
    Antonella Crescenti
    Department of Anaesthesia and Intensive Care, Vita Salute San Raffaele University, Milan 20132, Italy
    BMJ 343:d5701. 2011

Detail Information

Publications119 found, 100 shown here

  1. ncbi request reprint Volatile anesthetics for periprocedural cardiac protection. A review
    G Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Vita Salute San Raffaele University, Milan, Italy
    Minerva Cardioangiol 56:429-34. 2008
    ..Evidence in non-coronary surgical settings is contradictory and will be reviewed in this paper together with the mechanism of cardiac protection by volatile agents...
  2. ncbi request reprint Effects of levosimendan on mortality and hospitalization. A meta-analysis of randomized controlled studies
    Giovanni Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italy
    Crit Care Med 40:634-46. 2012
    ..Levosimendan is a calcium sensitizer that enhances myocardial contractility without increasing myocardial oxygen use. A meta-analysis was conducted to determine the impact of levosimendan on mortality and hospital stay...
  3. pmc Dexmedetomidine as a sedative agent in critically ill patients: a meta-analysis of randomized controlled trials
    Laura Pasin
    Anesthesia and Intensive Care Department, San Raffaele Scientific Institute, Milan, Italy
    PLoS ONE 8:e82913. 2013
    ..The effect of dexmedetomidine on length of intensive care unit (ICU) stay and time to extubation is still unclear...
  4. pmc Bystander-initiated chest compression-only CPR is better than standard CPR in out-of-hospital cardiac arrest
    L Cabrini
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    HSR Proc Intensive Care Cardiovasc Anesth 2:279-85. 2010
    ..We performed systematic review and meta-analysis of randomized controlled trials, focusing on survival at hospital discharge...
  5. pmc Fenoldopam to prevent renal replacement therapy after cardiac surgery. Design of the FENO-HSR study
    G Landoni
    Universita Vita Salute San Raffaele, Milano
    HSR Proc Intensive Care Cardiovasc Anesth 2:111-7. 2010
    ....
  6. pmc Mortality reduction in cardiac anesthesia and intensive care: results of the first International Consensus Conference
    G Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    HSR Proc Intensive Care Cardiovasc Anesth 3:9-19. 2011
    ..With the aim of identifying these measures, and suggesting measures for prioritized future investigation we performed the first international consensus conference on this topic...
  7. pmc A new method for managing emergency calls
    G Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    HSR Proc Intensive Care Cardiovasc Anesth 2:35-9. 2010
    ..If the operator is available he/she can precede or join the mobile unit on site, managing the emergency according to his/her profile, possibly in cooperation with the ambulance personnel and even up to hospital admission...
  8. pmc Percutaneous aortic valve implantation: the anesthesiologist perspective
    R D Covello
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    HSR Proc Intensive Care Cardiovasc Anesth 1:28-38. 2009
    ..In this new paper we describe the anesthesiological management of percutaneous aortic valve implantation at our Centre, reporting the results of our implantation program from November 2007 to February 2009...
  9. pmc Cardiac protection by volatile anesthetics in non-cardiac surgery? A meta-analysis of randomized controlled studies on clinically relevant endpoints
    G Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    HSR Proc Intensive Care Cardiovasc Anesth 1:34-43. 2009
    ..We therefore performed a meta-analysis of randomized studies to investigate this issue...
  10. pmc Intraoperative use of tranexamic acid to reduce transfusion rate in patients undergoing radical retropubic prostatectomy: double blind, randomised, placebo controlled trial
    Antonella Crescenti
    Department of Anaesthesia and Intensive Care, Vita Salute San Raffaele University, Milan 20132, Italy
    BMJ 343:d5701. 2011
    ..To determine the efficacy of intraoperative treatment with low dose tranexamic acid in reducing the rate of perioperative transfusions in patients undergoing radical retropubic prostatectomy...
  11. pmc The effect of statins on mortality in septic patients: a meta-analysis of randomized controlled trials
    Laura Pasin
    Department of Anesthesia and Intensive Care, San Raffaele Scientific Institute, Milan, Italy
    PLoS ONE 8:e82775. 2013
    ..We decided to perform a meta-analysis of all randomized controlled trials ever published on statin therapy in septic patients to evaluate their effect on survival and length of hospital stay...
  12. ncbi request reprint Reducing mortality in acute kidney injury patients: systematic review and international web-based survey
    Giovanni Landoni
    Department of Anesthesia and Intensive Care, San Raffaele Scientific Institute, Milan, Italy Electronic address
    J Cardiothorac Vasc Anesth 27:1384-98. 2013
    ..To identify all interventions that increase or reduce mortality in patients with acute kidney injury (AKI) and to establish the agreement between stated beliefs and actual practice in this setting...
  13. ncbi request reprint Effects of non-invasive ventilation on reintubation rate: a systematic review and meta-analysis of randomised studies of patients undergoing cardiothoracic surgery
    Luigi Olper
    San Raffaele Scientific Institute, Milan, Italy
    Crit Care Resusc 15:220-7. 2013
    ..To estimate the effect of non-invasive mechanical ventilation (NIV) on the rate of reintubation among patients undergoing cardiothoracic surgery...
  14. ncbi request reprint Metformin-associated lactic acidosis requiring hospitalization. A national 10 year survey and a systematic literature review
    F Renda
    Italian Medicines Agency, Rome, Italy
    Eur Rev Med Pharmacol Sci 17:45-9. 2013
    ..Metformin is known to be rarely associated with lactic acidosis, a serious condition with a poor prognosis...
  15. ncbi request reprint Randomized evidence for reduction of perioperative mortality
    Giovanni Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italy, Milan, Italy
    J Cardiothorac Vasc Anesth 26:764-72. 2012
    ..This international consensus conference aimed to identify all nonsurgical interventions that increase or reduce perioperative mortality as suggested by randomized evidence...
  16. doi request reprint Magic bullets in cardiac anesthesia and intensive care
    Giovanni Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 26:455-8. 2012
    ..Caring for critical patients involves making decisions based on realistic tradeoffs of clinical benefit and side effects, but too often these choices are made on the basis of extrapolations and educated guesses...
  17. ncbi request reprint Beneficial impact of fenoldopam in critically ill patients with or at risk for acute renal failure: a meta-analysis of randomized clinical trials
    Giovanni Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italia
    Am J Kidney Dis 49:56-68. 2007
    ..Because there is uncertainty about the benefits of fenoldopam in such a setting, we performed a systematic review of randomized controlled trials of intensive care unit patients or those undergoing major surgery...
  18. ncbi request reprint Halogenated anaesthetics and cardiac protection in cardiac and non-cardiac anaesthesia
    Giovanni Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italy
    Ann Card Anaesth 12:4-9. 2009
    ..Nonetheless, evidence in non-coronary surgical settings is contradictory and will be reviewed in this paper together with the mechanisms of cardiac protection by volatile agents...
  19. doi request reprint Fenoldopam reduces the need for renal replacement therapy and in-hospital death in cardiovascular surgery: a meta-analysis
    Giovanni Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italia e Istituto Scientifico San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 22:27-33. 2008
    ..To determine the efficacy of fenoldopam in the prevention of acute renal failure, the authors performed a systematic review of randomized, controlled trials and propensity-matched studies in patients undergoing cardiovascular surgery...
  20. ncbi request reprint Acute renal failure after isolated CABG surgery: six years of experience
    G Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Vita Salute San Raffaele University, San Raffaele Scientific Institute, Milan, Italy
    Minerva Anestesiol 73:559-65. 2007
    ..The effects of ARF on outcome were also investigated...
  21. ncbi request reprint Desflurane and sevoflurane in cardiac surgery: a meta-analysis of randomized clinical trials
    Giovanni Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Milan, Italy
    J Cardiothorac Vasc Anesth 21:502-11. 2007
    ..The authors performed a meta-analysis to investigate whether the cardioprotective effects of volatile anesthetics translate into decreased morbidity and mortality in patients undergoing cardiac surgery...
  22. ncbi request reprint Desflurane versus propofol in patients undergoing mitral valve surgery
    Giovanni Landoni
    Department of Cardiovascular Anesthesia, Universita Vita Salute San Raffaele, Milano, Italia e Istituto Scientifico San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 21:672-7. 2007
    ..This study compared cardiac troponin release in patients receiving either volatile anesthetics or total intravenous anesthesia for mitral valve surgery...
  23. ncbi request reprint Cardiac protection with volatile anesthetics in stenting procedures
    Giovanni Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele e Istituto Scientifico San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 22:543-7. 2008
    ..The authors tested the hypothesis that low-dose sevoflurane could decrease perioperative myocardial damage, as measured by cTnI release, when compared with placebo, in patients undergoing interventional cardiology procedures...
  24. ncbi request reprint Cardiac protection by volatile anaesthetics: a review
    Giovanni Landoni
    Department of Cardiothoracic Anesthesia, Universita, Vita Salute San Raffaele, Italia e Istituto Scientifico San Raffaele, Milan, Italy
    Curr Vasc Pharmacol 6:108-11. 2008
    ..Whether these cardioprotective properties also exist in non-coronary surgery settings is still controversial owing to the scarce available data...
  25. ncbi request reprint Reducing perioperative myocardial infarction with anesthetic drugs and techniques
    G Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italy
    Curr Drug Targets 10:858-62. 2009
    ..Until now no randomized trial can be considered powered enough to show a reduction on both perioperative myocardial infarction and mortality...
  26. ncbi request reprint Beating-heart coronary artery bypass graft surgery at San Raffaele Hospital: four years of experience
    G Landoni
    Department of Anesthesiology, Vita Salute University of Milano, IRCCS San Raffaele Hospital, Milano, Italy
    J Cardiothorac Vasc Anesth 16:691-4. 2002
    ....
  27. ncbi request reprint Cardiac protection by volatile anesthetics. A review
    G Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Vita Salute San Raffele University, Milan, Italy
    Minerva Anestesiol 75:269-73. 2009
    ..However, evidence in non-coronary surgical settings is contradictory and will be reviewed in this paper, together with the mechanism of cardiac protection by volatile agents...
  28. doi request reprint Publication trends in the journal of cardiothoracic and vascular anesthesia: a 10-year analysis
    Giovanni Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 24:969-73. 2010
    ..The aim of this article was to present and analyze the scientific contributions published in the Journal of Cardiothoracic and Vascular Anesthesia and to give a structured view focused on the countries where these studies were performed...
  29. ncbi request reprint Levosimendan reduces mortality in critically ill patients. A meta-analysis of randomized controlled studies
    G Landoni
    Department of Anesthesiology and Intensive Care, Vita Salute San Raffaele University, Milan, Italy
    Minerva Anestesiol 76:276-86. 2010
    ..Levosimendan is a calcium sensitizer that is able to enhance myocardial contractility without increasing myocardial oxygen use. We conducted a meta-analysis to determine the impact of levosimendan on mortality in critically ill patients...
  30. doi request reprint Mortality reduction in cardiac anesthesia and intensive care: results of the first International Consensus Conference
    G Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    Acta Anaesthesiol Scand 55:259-66. 2011
    ..The use of aprotinin and aged red blood cells may result in increased mortality...
  31. ncbi request reprint Organ protection by volatile anesthetics in non-coronary artery bypass grafting surgery
    Giovanni Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Istituto Scientifico San Raffaele, Milano, Italy
    Future Cardiol 5:589-603. 2009
    ..Furthermore, we focus on the emerging data from animal experiments, discussing in particular the molecular mechanisms underlying anesthetic preconditioning...
  32. ncbi request reprint Esmolol reduces perioperative ischemia in noncardiac surgery: a meta-analysis of randomized controlled studies
    Giovanni Landoni
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 24:219-29. 2010
    ..Recently, the POISE trial showed that beta-blockers could be harmful in the perioperative period. The authors performed a meta-analysis to evaluate the clinical effects of esmolol in noncardiac surgery...
  33. doi request reprint Reducing mortality in cardiac surgery with levosimendan: a meta-analysis of randomized controlled trials
    Giovanni Landoni
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Istituto Scientifico San Raffaele, Via Olgettina 60, Milano 20132, Italy
    J Cardiothorac Vasc Anesth 24:51-7. 2010
    ..The authors performed a meta-analysis to evaluate whether levosimendan is associated with improved survival in patients undergoing cardiac surgery...
  34. doi request reprint Validation of a decision-making strategy for systolic anterior motion following mitral valve repair
    Giovanni Landoni
    Anesthesia and Intensive Care Department, Universita Vita Salute San Raffaele, Milan, Italy
    Ann Card Anaesth 14:85-90. 2011
    ..We confirmed that SAM after a repair of a degenerative MV is common and validated a simple two-step conservative management method that allows to clearly identify those few patients who require immediate surgical revision...
  35. ncbi request reprint Long-term outcome of patients who require renal replacement therapy after cardiac surgery
    G Landoni
    Università Vita Salute di Milano, IRCCS San Raffaele Hospital, Department of Cardiovascular Anaesthesia and Intensive Care, Italy
    Eur J Anaesthesiol 23:17-22. 2006
    ..We studied the long-term survival and quality of life of patients requiring renal replacement therapy after cardiac surgery, since they represent a heavy burden on hospital resources and their outcome has never been adequately evaluated...
  36. ncbi request reprint The outcome of patients requiring emergency conversion from off-pump to on-pump coronary artery bypass grafting
    G Landoni
    Universita Vita Salute San Raffaele, Italia e Istituto Scientifico San Raffaele, Milan, Italy
    Eur J Anaesthesiol 24:317-22. 2007
    ..Our aim was to evaluate outcome in such patients and identify preoperative and intraoperative risk factors...
  37. doi request reprint Predictors of cardiac troponin release after mitral valve surgery
    Fabrizio Monaco
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 24:931-8. 2010
    ..Although cardiac troponin I (cTnI) measurement is used extensively as a marker of perioperative myocardial injury, limited knowledge exists in noncoronary artery bypass graft surgery...
  38. ncbi request reprint Cardiac index assessment by the pressure recording analytic method in critically ill unstable patients after cardiac surgery
    Luigi Barile
    Department of Anesthesia and Intensive Care, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    J Cardiothorac Vasc Anesth 27:1108-13. 2013
    ....
  39. ncbi request reprint Levosimendan reduces cardiac troponin release after cardiac surgery: a meta-analysis of randomized controlled studies
    Alberto Zangrillo
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 23:474-8. 2009
    ..Inotropic drugs have never shown beneficial effects on outcome in randomized controlled studies, with the possible exception of levosimendan...
  40. ncbi request reprint The effect of concomitant radiofrequency ablation and surgical technique (repair versus replacement) on release of cardiac biomarkers during mitral valve surgery
    Alberto Zangrillo
    Department of Cardiovascular Anesthesia, IRCCS San Raffaele Hospital, Milan, Italy, Via Olgettina 60, 20132 Milano Italy
    Anesth Analg 101:24-9, table of contents. 2005
    ....
  41. doi request reprint N-terminal B-natriuretic Peptide after coronary artery bypass graft surgery
    Giuseppe Crescenzi
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italia e Istituto Scientifico San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 23:147-50. 2009
    ..To investigate N-terminal amino-acid sequence of the B-natriuretic peptide (NT-proBNP) release and its prognostic characteristics after coronary artery bypass graft surgery with and without cardiopulmonary bypass...
  42. ncbi request reprint Clinical significance of a new Q wave after cardiac surgery
    Giuseppe Crescenzi
    Department of Cardiovascular Anesthesia, IRCCS San Raffaele Hospital of Milan, Via Olgettina, 60, 20132 Milan, Italy
    Eur J Cardiothorac Surg 25:1001-5. 2004
    ..The aim of this study was to investigate the clinical significance of new Q waves appearing following cardiac surgery and to correlate them with the release of myocardial cell damage biomarkers...
  43. doi request reprint Miniaturized cardiopulmonary bypass improves short-term outcome in cardiac surgery: a meta-analysis of randomized controlled studies
    Alberto Zangrillo
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Thorac Cardiovasc Surg 139:1162-9. 2010
    ..To investigate whether the use of miniaturized cardiopulmonary bypass translates into decreased morbidity and mortality in patients having cardiac surgery...
  44. doi request reprint Recombinant activated factor VII increases stroke in cardiac surgery: a meta-analysis
    Martin Ponschab
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 25:804-10. 2011
    ..Few clinical trials have investigated rFVIIa in cardiac surgery. The authors performed a meta-analysis focusing on the rate of stroke and surgical re-exploration...
  45. ncbi request reprint Role of cardiac biomarkers (troponin I and CK-MB) as predictors of quality of life and long-term outcome after cardiac surgery
    Elena Bignami
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italy
    Ann Card Anaesth 12:22-6. 2009
    ..Elevated cardiac biomarker release and length of hospital stay were the only postoperative independent predictors of death in this study...
  46. doi request reprint Recombinant activated factor VII in cardiac surgery: a meta-analysis
    Alberto Zangrillo
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italia
    J Cardiothorac Vasc Anesth 23:34-40. 2009
    ..Few trials have investigated rFVIIa and each individually lacked power to detect a beneficial effect on transfusion of blood products or thromboembolic side effects...
  47. doi request reprint Thoracic epidural anesthesia improves early outcome in patients undergoing cardiac surgery for mitral regurgitation: a propensity-matched study
    Fabrizio Monaco
    Anesthesia and Intensive Care Department, San Raffaele Scientific Institute, Milan, Italy
    J Cardiothorac Vasc Anesth 27:445-50. 2013
    ..The authors hypothesized that TEA might improve clinically relevant endpoints in patients with primary mitral regurgitation...
  48. doi request reprint Management and decision-making strategy for systolic anterior motion after mitral valve repair
    Giuseppe Crescenzi
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italia e Istituto Scientifico San Raffaele, Milan, Italy
    J Thorac Cardiovasc Surg 137:320-5. 2009
    ..Conventional hemodynamic measures require time and can be unsuccessful. While describing our experience, we propose a simple and innovative management and classification of this complication...
  49. doi request reprint Fenoldopam and acute renal failure in cardiac surgery: a meta-analysis of randomized placebo-controlled trials
    Alberto Zangrillo
    Department of Anesthesia, Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 26:407-13. 2012
    ....
  50. ncbi request reprint The easier, the better: age, creatinine, ejection fraction score for operative mortality risk stratification in a series of 29,659 patients undergoing elective cardiac surgery
    Marco Ranucci
    IRCCS Policlinico San Donato, Milan, Italy
    J Thorac Cardiovasc Surg 142:581-6. 2011
    ..We validate the age, creatinine, ejection fraction score in a large multicentric study...
  51. ncbi request reprint Renoprotective action of fenoldopam in high-risk patients undergoing cardiac surgery: a prospective, double-blind, randomized clinical trial
    Tiziana Bove
    Department of Cardiovascular Anesthesia, Vita Salute University of Milan, IRCCS San Raffaele Hospital, Milan, Italy
    Circulation 111:3230-5. 2005
    ..The aim of this study was to evaluate the usefulness of fenoldopam, a specific agonist of the dopamine-1 receptor, in patients at high risk of perioperative renal dysfunction...
  52. ncbi request reprint Spinal analgesia in cardiac surgery: a meta-analysis of randomized controlled trials
    Alberto Zangrillo
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 23:813-21. 2009
    ..The authors conducted a review of randomized studies to show whether there are any advantages in clinically relevant outcomes using spinal analgesia in patients undergoing cardiac surgery...
  53. ncbi request reprint Off-pump coronary artery bypass grafting reduces postoperative neurologic complications
    Alberto Zangrillo
    Department of Cardiovascular Anesthesia, IRCCS San Raffaele Hospital, Milan, Italy
    J Cardiothorac Vasc Anesth 19:193-6. 2005
    ..The aim of this work was to compare postoperative outcomes of patients undergoing CABG surgery, with or without the use of CPB, focusing on neurologic events...
  54. ncbi request reprint ECG changes after CABG: the role of the surgical technique
    Giuseppe Crescenzi
    Department of Cardiovascular Anesthesia, San Raffele Hospital, University of Milan, Milan, Italy
    J Cardiothorac Vasc Anesth 18:38-42. 2004
    ....
  55. doi request reprint Surgical and transcatheter aortic valve procedures. The limits of risk scores
    Marco Ranucci
    Department of Cardiothoracic Anesthesia and Intensive Care, IRCCS Policlinico S Donato, Via Morandi 30, 20097 San Donato Milanese, Milan, Italy
    Interact Cardiovasc Thorac Surg 11:138-41. 2010
    ..These risk conditions should be included in a specific risk model for referring patients for TAVI...
  56. doi request reprint Intrathecal lactate concentration and spinal cord injury in thoracoabdominal aortic surgery
    Giuseppina Casiraghi
    Department of Anesthesia and Intensive Care, Milan, Italy
    J Cardiothorac Vasc Anesth 25:120-6. 2011
    ..The aim of this study was to evaluate the role of lactate as an early predictor of spinal cord injury during thoracoabdominal aortic aneurysm repair...
  57. ncbi request reprint Perioperative magnesium supplementation to prevent atrial fibrillation after off-pump coronary artery surgery: a randomized controlled study
    Alberto Zangrillo
    Department of Cardiothoracic and Vascular Anesthesia, Vita Salute University of Milano, Milan, Italy
    J Cardiothorac Vasc Anesth 19:723-8. 2005
    ..The authors performed a study to evaluate the role of perioperative magnesium for prophylaxis of atrial fibrillation after off-pump coronary artery surgery...
  58. doi request reprint The effect of isoflurane on survival and myocardial infarction: a meta-analysis of randomized controlled studies
    Elena Bignami
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 27:50-8. 2013
    ..The aim of this meta-analysis was to investigate the cardioprotective properties of isoflurane versus any comparator in terms of the rate of myocardial infarction and all-cause mortality...
  59. ncbi request reprint Methylene blue as a vasopressor: a meta-analysis of randomised trials
    Laura Pasin
    Department of Anesthesia and Intensive Care, San Raffaele Scientific Institute, Milan, Italy
    Crit Care Resusc 15:42-8. 2013
    ..To evaluate the efficacy of methylene blue in raising mean arterial pressure in hypotensive patients...
  60. doi request reprint A comprehensive appraisal of meta-analyses focusing on nonsurgical treatments aimed at decreasing perioperative mortality or major cardiac complications
    Massimo Zambon
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Anesth 26:509-15. 2012
    ..We describe characteristics of meta-analyses on ancillary treatments aimed at improving surgical outcomes and explore factors associated with scholarly citations...
  61. doi request reprint Milrinone and mortality in adult cardiac surgery: a meta-analysis
    Alberto Zangrillo
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 26:70-7. 2012
    ..The authors conducted a review of randomized studies to show whether there are any increases or decreases in survival when using milrinone in patients undergoing cardiac surgery...
  62. ncbi request reprint The incidence and risk of acute renal failure after cardiac surgery
    Tiziana Bove
    Department of Cardiovascular Anesthesia, Vita Salute University IRCCS San Raffaele Hospital, via Olgettina degree 60 20132 Milano, Italy
    J Cardiothorac Vasc Anesth 18:442-5. 2004
    ..To evaluate outcome and risk factors of acute renal failure in a surgical population with or without preoperative renal dysfunction...
  63. ncbi request reprint Epidural anesthesia in elderly patients undergoing coronary artery bypass graft surgery
    Giuseppe Crescenzi
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 23:807-12. 2009
    ....
  64. ncbi request reprint A meta-analysis of complications and mortality of extracorporeal membrane oxygenation
    Alberto Zangrillo
    Department of Anesthesia and Intensive Care, San Raffaele Scientific Institute, Milan, Italy
    Crit Care Resusc 15:172-8. 2013
    ..To comprehensively assess published peer-reviewed studies related to extracorporeal membrane oxygenation (ECMO), focusing on outcomes and complications of ECMO in adult patients...
  65. doi request reprint Cardiac index assessment by the pressure recording analytic method in unstable patients with atrial fibrillation
    Giulia Maj
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 25:476-80. 2011
    ..The purpose of this study was to confirm the reliability of cardiac index determinations by Most-Care in unstable patients with atrial fibrillation...
  66. doi request reprint Volatile agents for cardiac protection in noncardiac surgery: a randomized controlled study
    Alberto Zangrillo
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 25:902-7. 2011
    ....
  67. ncbi request reprint Predictors of atrial fibrillation after off-pump coronary artery bypass graft surgery
    Alberto Zangrillo
    Department of Cardiovascular Anesthesia, IRCCS San Raffaele Hospital, Milan, Italy
    J Cardiothorac Vasc Anesth 18:704-8. 2004
    ..The purpose of this study was to identify perioperative characteristics associated with new-onset atrial fibrillation in patients undergoing off-pump coronary artery bypass grafting...
  68. ncbi request reprint Cardiac biomarker release after CABG with different surgical techniques
    Giuseppe Crescenzi
    Department of Cardiovascular Anesthesia, IRCCS San Raffele Hospital, Milano, Italy
    J Cardiothorac Vasc Anesth 18:34-7. 2004
    ..To investigate the release of cardiac biomarkers (troponin I and CK-MB) in patients undergoing coronary artery bypass graft (CABG) with or without cardiopulmonary bypass (CPB)...
  69. ncbi request reprint Human protein C zymogen concentrate in patients with severe sepsis and multiple organ failure after adult cardiac surgery
    Martina Crivellari
    Department of Cardiac Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Via Olgettina 60 Milano, Milan, 20132, Italy
    Intensive Care Med 35:1959-63. 2009
    ..To describe outcome and changes in clotting and inflammatory parameters in an uncontrolled case series of consecutive patients with severe sepsis who received protein C concentrate soon after cardiac surgery...
  70. doi request reprint Remifentanil in cardiac surgery: a meta-analysis of randomized controlled trials
    Massimiliano Greco
    Department of Anesthesiology and Intensive Care, Vita Salute San Raffaele University, Milan, Italy
    J Cardiothorac Vasc Anesth 26:110-6. 2012
    ..The authors conducted a review of randomized controlled trials to identify advantages in clinically relevant outcomes in patients undergoing cardiac surgery with remifentanil...
  71. doi request reprint Urinary neutrophil gelatinase-associated lipocalin as an early predictor of prolonged intensive care unit stay after cardiac surgery
    Elena Bignami
    Department of Anaesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italy
    Ann Card Anaesth 15:13-7. 2012
    ..At a multivariate analysis the only independent predictors of prolonged ICU stay were BMI, uNGAL 24 h after surgery and aortic cross-clamp time...
  72. doi request reprint Esmolol reduces perioperative ischemia in cardiac surgery: a meta-analysis of randomized controlled studies
    Alberto Zangrillo
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 23:625-32. 2009
    ..Esmolol is an ultra-short-acting beta-blocker mostly used in emergency and high-risk patients. The authors performed a meta-analysis to evaluate the clinical effects of esmolol in cardiac surgery...
  73. doi request reprint Desmopressin reduces transfusion needs after surgery: a meta-analysis of randomized clinical trials
    Giuseppe Crescenzi
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italy
    Anesthesiology 109:1063-76. 2008
    ..The authors performed a meta-analysis of 38 randomized, placebo-controlled trials (2,488 patients) investigating desmopressin in surgery and indicating at least perioperative blood loss or transfusion of blood products...
  74. doi request reprint Volatile anesthetics reduce mortality in cardiac surgery
    Elena Bignami
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 23:594-9. 2009
    ..A survey was conducted among these centers to investigate whether the use of volatile anesthetics showed a correlation with mortality...
  75. pmc Effects of vasopressinergic receptor agonists on sublingual microcirculation in norepinephrine-dependent septic shock
    Andrea Morelli
    Department of Anesthesiology and Intensive Care, University of Rome, La Sapienza, Viale del Policlinico 155, Rome I 00161, Italy
    Crit Care 15:R217. 2011
    ..The primary study end point was a difference of ≥ 20% in the microvascular flow index of small vessels among groups...
  76. doi request reprint Remifentanil in critically ill cardiac patients
    Laura Ruggeri
    Department of Anesthesia and Intensive Care Medicine, Universita Vita Salute San Raffaele, Milan, Italy
    Ann Card Anaesth 14:6-12. 2011
    ..e. chest drain removal). In conclusion, thanks to its peculiar properties, remifentanil will probably play a major role in critically ill cardiac patients...
  77. ncbi request reprint Cardiac index validation using the pressure recording analytic method in unstable patients
    Alberto Zangrillo
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italy
    J Cardiothorac Vasc Anesth 24:265-9. 2010
    ....
  78. ncbi request reprint Long-term outcome and quality of life of patients requiring prolonged mechanical ventilation after cardiac surgery
    Federico Pappalardo
    Department of Cardiovascular Anesthesia and Intensive Care, San Raffaele Hospital, Vita Salute University, Via Olgettina 60, 20132 Milano, Italy
    Eur J Cardiothorac Surg 25:548-52. 2004
    ....
  79. ncbi request reprint Epidural analgesia improves outcome in cardiac surgery: a meta-analysis of randomized controlled trials
    Elena Bignami
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italy
    J Cardiothorac Vasc Anesth 24:586-97. 2010
    ..The authors conducted a review of randomized studies to determine whether there were any advantages for clinically relevant outcomes by adding epidural analgesia in patients undergoing cardiac surgery under general anesthesia...
  80. ncbi request reprint Noninvasive ventilation outside the intensive care unit from the patient point of view: a pilot study
    Luca Cabrini
    Department of Anesthesia and Intensive Care, Ospedale Istituto Scientifico San Raffaele, Milan, Italy
    Respir Care 57:704-9. 2012
    ..So far, no study has evaluated the perspective of the patient, despite the known high relevance of patient participation for NIV success...
  81. pmc Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study
    Andrea Morelli
    Department of Anesthesiology and Intensive Care, University of Rome, La Sapienza, Viale del Policlinico 155, Rome 00161, Italy
    Crit Care 14:R232. 2010
    ..e. dobutamine). The primary end point was a difference of ≥ 20% in the microvascular flow index of small vessels (MFIs) among groups...
  82. doi request reprint Anesthetic management of transcatheter aortic valve implantation
    Remo D Covello
    Anaesthesia and Intensive Care Medicine, Universita Vita Salute San Raffaele, Milan, Italy
    Curr Opin Anaesthesiol 24:417-25. 2011
    ..The aim of this review is to describe the challenges of the anesthetic management related to TAVI...
  83. doi request reprint Anesthetic management of percutaneous aortic valve implantation: focus on challenges encountered and proposed solutions
    Remo Daniel Covello
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 23:280-5. 2009
    ..To describe 6 months of experience in the anesthetic management of percutaneous aortic valve implantation...
  84. ncbi request reprint Temperature management during off-pump coronary artery bypass graft surgery: a randomized clinical trial on the efficacy of a circulating water system versus a forced-air system
    Alberto Zangrillo
    Department of Cardiovascular Anesthesia and Intensive Care, IRCCS San Raffaele Hospital, Milan, Italy
    J Cardiothorac Vasc Anesth 20:788-92. 2006
    ....
  85. ncbi request reprint Methicillin-resistant Staphylococcus species in a cardiac surgical intensive care unit: a 5-year experience
    Alberto Zangrillo
    Department of Cardiovascular Anesthesia, Vita Salute University of Milan, IRCCS San Raffaele Hospital, Milan, Italy
    J Cardiothorac Vasc Anesth 20:31-7. 2006
    ..The aim of this study was to describe the epidemiology of methicillin-resistant Staphylococcus isolates in a cardiac surgical ICU over a 5-year period and to determine the risk factors and outcome of this condition...
  86. ncbi request reprint How to explain a PaO2 of 140 mmHg in a venous line?
    Anna Mizzi
    Department of Anesthesia and Intensive Care, Vita Salute San Raffaele University, Milan, Italy
    Acta Biomed 80:262-4. 2009
    ..Considering that metformin acts on mitochondrial respiration, the dilemma may be explained by hypothesizing a cellular respiration block caused by metformin or severe acidosis. (www.actabiomedica.it)..
  87. ncbi request reprint Fenoldopam infusion for renal protection in high-risk cardiac surgery patients: a randomized clinical study
    Andrea A Cogliati
    Department of Anesthesia and Intensive Care, Villa Maria Cecilia Hospital, Cotignola, Ravenna, Italy
    J Cardiothorac Vasc Anesth 21:847-50. 2007
    ..The purpose of this study was to evaluate the renoprotective effects of fenoldopam in patients at high risk of postoperative acute kidney injury undergoing elective cardiac surgery requiring cardiopulmonary bypass...
  88. ncbi request reprint Impact of impedance threshold devices on cardiopulmonary resuscitation: a systematic review and meta-analysis of randomized controlled studies
    Luca Cabrini
    Department of Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, and Istituto Scientifico San Raffaele, Milan, Italy
    Crit Care Med 36:1625-32. 2008
    ..This review provides an update on the impedance threshold device and underlines its effect on short-term survival...
  89. ncbi request reprint Redo coronary artery bypass grafting on the beating heart and transfusion needs
    C Gerli
    Department of Cardiovascular Anesthesia, IRCCS San Raffaele Hospital, Milan, Italy
    Minerva Anestesiol 72:985-93. 2006
    ..We investigated our 5-year database to evaluate the role of off pump technique in reducing transfusion needs...
  90. ncbi request reprint Recombinant activated factor VII for refractory bleeding after acute aortic dissection surgery: a propensity score analysis
    Luigi Tritapepe
    Department of Anesthesiology and Intensive Care, University of Rome La Sapienza, Rome, Italy
    Crit Care Med 35:1685-90. 2007
    ..The aim of this study was to assess safety and effectiveness of recombinant activated factor VII (rFVIIa) in patients with refractory bleeding undergoing acute aortic dissection surgery with deep hypothermic circulatory arrest...
  91. ncbi request reprint Dilated coronary sinus and a ring structure between the left atrial appendage and the left superior pulmonary vein
    Giuseppe Crescenzi
    Department of Cardiothoracic Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Milano, Italia e Istituto Scientifico San Raffaele, Milan, Italy
    J Cardiothorac Vasc Anesth 21:761-2. 2007
  92. ncbi request reprint Methylene blue for lithium-induced refractory hypotension in off-pump coronary artery bypass graft: report of two cases
    Donatella Sparicio
    Department of Cardiovascular Anesthesia, Vita Salute University of Milan, IRCCS San Raffaele Hospital, Italy
    J Thorac Cardiovasc Surg 127:592-3. 2004
  93. ncbi request reprint Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation
    Carlo Pappone
    Department of Cardiology, San Raffaele University Hospital, Via Olgettina 60, 20132, Milan, Italy
    Circulation 109:327-34. 2004
    ..This study assesses the incremental benefit of vagal denervation by radiofrequency in preventing recurrent AF in a large series of patients undergoing CPVA for paroxysmal AF...
  94. ncbi request reprint Transcatheter implantation of an aortic valve: anesthesiological management
    R D Covello
    Department of Anesthesia and Intensive Care, Vita Salute San Raffaele University, Milan, Italy
    Minerva Anestesiol 76:100-8. 2010
    ..Here, we describe the anesthesiological management of patients undergoing TAVI at our institution over an 18-month period...
  95. ncbi request reprint A propensity score analysis on the effect of eliminating cardiopulmonary bypass for coronary artery bypass grafting
    G Crescenzi
    Department of Cardiothoracic and Vascular Anesthesia and Intensive Care, Universita Vita Salute San Raffaele, Istituto San Raffaele, Milan, Italy
    Minerva Anestesiol 73:135-41. 2007
    ..The aim of the study was to investigate if the off-pump technique could reduce the hospital mortality after coronary artery bypass grafting when compared to the standard cardiopulmonary bypass (CPB) technique...
  96. ncbi request reprint Reduction of hemodilution in small adults undergoing open heart surgery: a prospective, randomized trial
    F Pappalardo
    Department of Cardiovascular Anesthesia and Intensive Care, San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy
    Perfusion 22:317-22. 2007
    ..Smaller patients are more likely to have a low hematocrit during CPB: this phenomenon may be related, at least partially, to the extreme hemodilution induced by a large fixed CPB priming volume...
  97. ncbi request reprint Elective cardiac anesthesia in a nonagenarian
    G Landoni
    Department of Anesthesiology, Vita Salute University of Milano, Milan, Italy
    J Cardiothorac Vasc Anesth 17:647-54. 2003