Claudio Fiorino

Summary

Affiliation: San Raffaele Scientific Institute
Country: Italy

Publications

  1. doi request reprint Intensity-modulated proton therapy versus helical tomotherapy in nasopharynx cancer: planning comparison and NTCP evaluation
    Lamberto Widesott
    ATreP Provincial Agency for Proton Therapy, Trento, Italy
    Int J Radiat Oncol Biol Phys 72:589-96. 2008
  2. ncbi request reprint Density variation of parotid glands during IMRT for head-neck cancer: correlation with treatment and anatomical parameters
    Claudio Fiorino
    San Raffaele Scientific Institute, Milano, Italy
    Radiother Oncol 104:224-9. 2012
  3. ncbi request reprint Late fecal incontinence after high-dose radiotherapy for prostate cancer: better prediction using longitudinal definitions
    Claudio Fiorino
    Department of Medical Physics, San Raffaele Scientific Institute, Milano, Italy
    Int J Radiat Oncol Biol Phys 83:38-45. 2012
  4. ncbi request reprint Simultaneous integrated boost (SIB) for nasopharynx cancer with helical tomotherapy. A planning study
    Claudio Fiorino
    Medical Physics, S Raffaele Institute, Milano, Italy
    Strahlenther Onkol 183:497-505. 2007
  5. ncbi request reprint Physics aspects of prostate tomotherapy: planning optimization and image-guidance issues
    Claudio Fiorino
    Medical Physics, S Raffaele Institute, Milano, Italy
    Acta Oncol 47:1309-16. 2008
  6. doi request reprint Introducing the Jacobian-volume-histogram of deforming organs: application to parotid shrinkage evaluation
    Claudio Fiorino
    Medical Physics, San Raffaele Scientific Institute, Milano, Italy
    Phys Med Biol 56:3301-12. 2011
  7. ncbi request reprint Rectal dose-volume constraints in high-dose radiotherapy of localized prostate cancer
    Claudio Fiorino
    Department of Medical Physics and Radiotherapy, H S Raffaele, Milano, Italy
    Int J Radiat Oncol Biol Phys 57:953-62. 2003
  8. ncbi request reprint A cylindrical model of the rectum: comparing dose-volume, dose-surface and dose-wall histograms in the radiotherapy of prostate cancer
    Claudio Fiorino
    Medical Physics, Servizio di Fisica Sanitaria, H S Raffaele, Via Olgettina 60, 20132 Milano, Italy
    Phys Med Biol 48:2603-16. 2003
  9. ncbi request reprint Clinical and dosimetric predictors of late rectal syndrome after 3D-CRT for localized prostate cancer: preliminary results of a multicenter prospective study
    Claudio Fiorino
    Department of Medical Physics, Ospedale San Raffaele, Milan, Italy
    Int J Radiat Oncol Biol Phys 70:1130-7. 2008
  10. doi request reprint Dose-volume relationships for acute bowel toxicity in patients treated with pelvic nodal irradiation for prostate cancer
    Claudio Fiorino
    Department of Medical Physics, San Raffaele Scientific Institute, Milan, Italy
    Int J Radiat Oncol Biol Phys 75:29-35. 2009

Collaborators

Detail Information

Publications70

  1. doi request reprint Intensity-modulated proton therapy versus helical tomotherapy in nasopharynx cancer: planning comparison and NTCP evaluation
    Lamberto Widesott
    ATreP Provincial Agency for Proton Therapy, Trento, Italy
    Int J Radiat Oncol Biol Phys 72:589-96. 2008
    ..To compare intensity-modulated proton therapy (IMPT) and helical tomotherapy (HT) treatment plans for nasopharynx cancer using a simultaneous integrated boost approach...
  2. ncbi request reprint Density variation of parotid glands during IMRT for head-neck cancer: correlation with treatment and anatomical parameters
    Claudio Fiorino
    San Raffaele Scientific Institute, Milano, Italy
    Radiother Oncol 104:224-9. 2012
    ..Measuring parotid density changes in patients treated with IMRT for head-neck cancer (HNC) and assessing correlation with treatment-related parameters...
  3. ncbi request reprint Late fecal incontinence after high-dose radiotherapy for prostate cancer: better prediction using longitudinal definitions
    Claudio Fiorino
    Department of Medical Physics, San Raffaele Scientific Institute, Milano, Italy
    Int J Radiat Oncol Biol Phys 83:38-45. 2012
    ....
  4. ncbi request reprint Simultaneous integrated boost (SIB) for nasopharynx cancer with helical tomotherapy. A planning study
    Claudio Fiorino
    Medical Physics, S Raffaele Institute, Milano, Italy
    Strahlenther Onkol 183:497-505. 2007
    ..To explore the potential of helical tomotherapy (HT) in the treatment of nasopharynx cancer...
  5. ncbi request reprint Physics aspects of prostate tomotherapy: planning optimization and image-guidance issues
    Claudio Fiorino
    Medical Physics, S Raffaele Institute, Milano, Italy
    Acta Oncol 47:1309-16. 2008
    ..To review planning and image-guidance aspects of more than 3 years experience in the treatment of prostate cancer with Helical Tomotherapy (HT)...
  6. doi request reprint Introducing the Jacobian-volume-histogram of deforming organs: application to parotid shrinkage evaluation
    Claudio Fiorino
    Medical Physics, San Raffaele Scientific Institute, Milano, Italy
    Phys Med Biol 56:3301-12. 2011
    ..5<7.5%, median value) was V15 ≥ 75% (OR: 7.6, p = 0.002). Jac and the JVH are promising tools for scoring/modelling toxicity and for evaluating organ/contour variations with potential applications in adaptive radiotherapy...
  7. ncbi request reprint Rectal dose-volume constraints in high-dose radiotherapy of localized prostate cancer
    Claudio Fiorino
    Department of Medical Physics and Radiotherapy, H S Raffaele, Milano, Italy
    Int J Radiat Oncol Biol Phys 57:953-62. 2003
    ..To investigate the relationship between rectal bleeding and dosimetric-clinical parameters in patients receiving three-dimensional conformal radiotherapy (3D-CRT) for localized prostate cancer...
  8. ncbi request reprint A cylindrical model of the rectum: comparing dose-volume, dose-surface and dose-wall histograms in the radiotherapy of prostate cancer
    Claudio Fiorino
    Medical Physics, Servizio di Fisica Sanitaria, H S Raffaele, Via Olgettina 60, 20132 Milano, Italy
    Phys Med Biol 48:2603-16. 2003
    ..In summary, except for the case of a 'very full' rectum, NDVH may be used as a robust surrogate for DWH. The DVH seems to be sufficiently robust if the rectum is prevalently empty...
  9. ncbi request reprint Clinical and dosimetric predictors of late rectal syndrome after 3D-CRT for localized prostate cancer: preliminary results of a multicenter prospective study
    Claudio Fiorino
    Department of Medical Physics, Ospedale San Raffaele, Milan, Italy
    Int J Radiat Oncol Biol Phys 70:1130-7. 2008
    ..To assess the predictors of late rectal toxicity in a prospectively investigated group of patients treated at 70-80 Gy for prostate cancer (1.8-2 Gy fractions) with three-dimensional conformal radiotherapy...
  10. doi request reprint Dose-volume relationships for acute bowel toxicity in patients treated with pelvic nodal irradiation for prostate cancer
    Claudio Fiorino
    Department of Medical Physics, San Raffaele Scientific Institute, Milan, Italy
    Int J Radiat Oncol Biol Phys 75:29-35. 2009
    ..To find correlation between dose-volume histograms (DVHs) of the intestinal cavity (IC) and moderate-severe acute bowel toxicity in men with prostate cancer treated with pelvic nodal irradiation...
  11. ncbi request reprint Predictive models of toxicity in external radiotherapy: dosimetric issues
    Claudio Fiorino
    Department of Medical Physics, San Raffaele Hospital, Milan, Italy
    Cancer 115:3135-40. 2009
    ..Cancer 2009;115(13 suppl):3135-40. (c) 2009 American Cancer Society...
  12. ncbi request reprint Dose-volume effects for normal tissues in external radiotherapy: pelvis
    Claudio Fiorino
    Medical Physics Department, San Raffaele Scientific Institute, Milan, Italy
    Radiother Oncol 93:153-67. 2009
    ..Quantitative data on bladder, bowel, sexual organs and pelvic bone marrow are more lacking but are rapidly emerging; however, for these organs, further investigation on large groups of patients is necessary...
  13. ncbi request reprint Significant improvement in normal tissue sparing and target coverage for head and neck cancer by means of helical tomotherapy
    Claudio Fiorino
    Medical Physics, Department of Radiotherapy, S Raffaele Institute, Milano, Italy
    Radiother Oncol 78:276-82. 2006
    ....
  14. doi request reprint Sparing the penile bulb in the radical irradiation of clinically localised prostate carcinoma: A comparison between MRI and CT prostatic apex definition in 3DCRT, Linac-IMRT and Helical Tomotherapy
    Lucia Perna
    Medical Physics, S Raffaele Institute, Milano, Italy
    Radiother Oncol 93:57-63. 2009
    ..To assess the impact of using MRI and Helical Tomotherapy (HT) compared to 3DCRT and dynamic IMRT on the dose to the penile bulb (PB)...
  15. doi request reprint Evidence of limited motion of the prostate by carefully emptying the rectum as assessed by daily MVCT image guidance with helical tomotherapy
    Claudio Fiorino
    Medical Physics, S Raffaele Institute, Milano, Italy
    Int J Radiat Oncol Biol Phys 71:611-7. 2008
    ..To assess setup and organ motion error by means of analysis of daily megavoltage computed tomography (MVCT) of patients treated with hypofractionated helical tomotherapy (71.4-74.2 Gy in 28 fractions)...
  16. doi request reprint Clinical factors predicting late severe urinary toxicity after postoperative radiotherapy for prostate carcinoma: a single-institute analysis of 742 patients
    Cesare Cozzarini
    Department of Radiotherapy, San Raffaele Scientific Institute, Milan, Italy
    Int J Radiat Oncol Biol Phys 82:191-9. 2012
    ..To investigate the clinical factors independently predictive of long-term severe urinary sequelae after postprostatectomy radiotherapy...
  17. ncbi request reprint Development of a set of nomograms to predict acute lower gastrointestinal toxicity for prostate cancer 3D-CRT
    Riccardo Valdagni
    Prostate Programme, Fondazione IRCCS, Istituto Nazionale dei Tumori, Milano, Italy
    Int J Radiat Oncol Biol Phys 71:1065-73. 2008
    ....
  18. doi request reprint PET-guided dose escalation tomotherapy in malignant pleural mesothelioma
    Andrei Fodor
    Department of Radiotherapy, San Raffaele Scientific Institute, Milan, Italy
    Strahlenther Onkol 187:736-43. 2011
    ..To test the feasibility of salvage radiotherapy using PET-guided helical tomotherapy in patients with progressive malignant pleural mesothelioma (MPM)...
  19. doi request reprint Hypofractionated adjuvant radiotherapy with helical tomotherapy after radical prostatectomy: planning data and toxicity results of a Phase I-II study
    Cesare Cozzarini
    Department of Radiotherapy, and Scientifc Institute H San Raffaele, Milan, Italy
    Radiother Oncol 88:26-33. 2008
    ..To report on planning and toxicity findings of hypofractionated adjuvant radiotherapy with helical Tomotherapy (HTT) after radical prostatectomy (RP) for prostate carcinoma (pCa)...
  20. doi request reprint Increasing the risk of late rectal bleeding after high-dose radiotherapy for prostate cancer: the case of previous abdominal surgery. Results from a prospective trial
    Riccardo Valdagni
    Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
    Radiother Oncol 103:252-5. 2012
    ..To evaluate and discuss the role of specific types of abdominal surgery (SURG) before radical radiation therapy as a risk factor for late rectal toxicity in prostate cancer patients...
  21. doi request reprint To bleed or not to bleed. A prediction based on individual gene profiling combined with dose-volume histogram shapes in prostate cancer patients undergoing three-dimensional conformal radiation therapy
    Riccardo Valdagni
    Prostate Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
    Int J Radiat Oncol Biol Phys 74:1431-40. 2009
    ..Thirty-five genes involved in DNA repair/radiation response were analyzed in patients accrued in the AIROPROS 0101 trial, which investigated the correlation between LRB and dosimetric parameters...
  22. ncbi request reprint Inclusion of clinical risk factors into NTCP modelling of late rectal toxicity after high dose radiotherapy for prostate cancer
    Tiziana Rancati
    Prostate Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
    Radiother Oncol 100:124-30. 2011
    ..To fit an NTCP model including clinical risk factors to late rectal toxicities after radiotherapy for prostate cancer...
  23. doi request reprint Phase I-II study of hypofractionated simultaneous integrated boost with tomotherapy for prostate cancer
    Nadia Di Muzio
    Department of Radiotherapy, Scientific Institute San Raffaele, Milan, Italy
    Int J Radiat Oncol Biol Phys 74:392-8. 2009
    ..To report planning and acute toxicity data of the first 60 patients treated within a Phase I-II study with moderate hypofractionation by image-guided helical tomotherapy...
  24. ncbi request reprint Need for high radiation dose (>or=70 gy) in early postoperative irradiation after radical prostatectomy: a single-institution analysis of 334 high-risk, node-negative patients
    Cesare Cozzarini
    Department of Radiotherapy, Scientific Institute Hospital San Raffaele, Milan, Italy
    Int J Radiat Oncol Biol Phys 75:966-74. 2009
    ..To determine the clinical benefit of high-dose early adjuvant radiotherapy (EART) in high-risk prostate cancer (hrCaP) patients submitted to radical retropubic prostatectomy plus pelvic lymphadenectomy...
  25. doi request reprint Survival following biochemical recurrence after radical prostatectomy and adjuvant radiotherapy in patients with prostate cancer: the impact of competing causes of mortality and patient stratification
    Firas Abdollah
    Department of Urology, Vita Salute University, San Raffaele, Milan, Italy
    Eur Urol 64:557-64. 2013
    ..Data regarding the natural history of biochemical recurrence (BCR) after radical prostatectomy (RP) and adjuvant radiotherapy (aRT) are limited...
  26. ncbi request reprint A reappraisal of the role of vesicourethral anastomosis biopsy in patient candidates for salvage radiation therapy after radical prostatectomy
    Marco Roscigno
    Department of Urology, Vita Salute University, Milan, Italy
    Radiother Oncol 82:30-7. 2007
    ..To investigate the usefulness of vesicourethral anastomotic biopsy (VUBx) in patients who are candidates for salvage radiotherapy (SalvRT) after radical prostatectomy (RRP)...
  27. ncbi request reprint Significant correlation between rectal DVH and late bleeding in patients treated after radical prostatectomy with conformal or conventional radiotherapy (66.6-70.2 Gy)
    Cesare Cozzarini
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    Int J Radiat Oncol Biol Phys 55:688-94. 2003
    ..Investigating the correlation between dosimetric/clinical parameters and late rectal bleeding in patients treated with adjuvant or salvage radiotherapy after radical prostatectomy...
  28. ncbi request reprint Comparing 3DCRT and inversely optimized IMRT planning for head and neck cancer: equivalence between step-and-shoot and sliding window techniques
    Barbara Longobardi
    Medical Physics, Servizio di Fisica Sanitaria, H S Raffaele, Milano, Italy
    Radiother Oncol 77:148-56. 2005
    ..To investigate the feasibility and the advantages of using Intensity-Modulated Radiotherapy (IMRT) for the treatment of head-and-neck cancer. Comparing different methods to deliver IMRT in this clinical setting...
  29. doi request reprint A two-variable linear model of parotid shrinkage during IMRT for head and neck cancer
    Sara Broggi
    Medical Physics Department, San Raffaele Scientific Institute, Milano, Italy
    Radiother Oncol 94:206-12. 2010
    ..To assess anatomical, clinical and dosimetric pre-treatment parameters, possibly predictors of parotid shrinkage during radiotherapy of head and neck cancer (HNC)...
  30. ncbi request reprint Predictors for rectal and intestinal acute toxicities during prostate cancer high-dose 3D-CRT: results of a prospective multicenter study
    Vittorio Vavassori
    Department of Radiotherapy, Ospedale di Circolo, Varese, Italy
    Int J Radiat Oncol Biol Phys 67:1401-10. 2007
    ..To find predictors for rectal and intestinal acute toxicity in patients with prostate cancer treated with > or =70 Gy conformal radiotherapy...
  31. doi request reprint Predictors of acute bowel toxicity in patients treated with IMRT whole pelvis irradiation after prostatectomy
    Lucia Perna
    Medical Physics, San Raffaele Scientific Institute, Milan, Italy
    Radiother Oncol 97:71-5. 2010
    ..Whole pelvis irradiation with IMRT (WPRT-IMRT) after prostatectomy is efficient in reducing acute toxicity: however, a number of patients still experience moderate acute bowel toxicity...
  32. doi request reprint Treatment planning comparison between conformal radiotherapy and helical tomotherapy in the case of locally advanced-stage NSCLC
    Giovanni Mauro Cattaneo
    Medical Physics, University of Milano Bicocca, Milano, Italy
    Radiother Oncol 88:310-8. 2008
    ..To investigate the impact of Helical Tomotherapy (HT) upon the dose distribution when compared to our routinely delivered 3D conformal radiotherapy (CRT) in the case of patients affected by stage III non-small-cell lung cancer (NSCLC)...
  33. doi request reprint Selecting the optimal candidate for adjuvant radiotherapy after radical prostatectomy for prostate cancer: a long-term survival analysis
    Firas Abdollah
    Department of Urology, Vita Salute University, San Raffaele, Milan, Italy
    Eur Urol 63:998-1008. 2013
    ..The role of adjuvant radiotherapy (ART) after radical prostatectomy (RP) on survival of patients with prostate cancer (PCa) is still controversial...
  34. doi request reprint Impact of the radiotherapy technique on the correlation between dose-volume histograms of the bladder wall defined on MRI imaging and dose-volume/surface histograms in prostate cancer patients
    Angelo Maggio
    Department of Medical Physics, IRCC Institute for Cancer Research, Candiolo, Italy
    Phys Med Biol 58:N115-23. 2013
    ..7 for most of parameters). When comparing the two treatment techniques, more pronounced differences between relative histograms were seen for IMRT with respect to 3DCRT (p < 0.0001)...
  35. pmc Inter-observer variability in contouring the penile bulb on CT images for prostate cancer treatment planning
    Lucia Perna
    San Raffaele Scientific Insitute, Milano, Italy
    Radiat Oncol 6:123. 2011
    ....
  36. ncbi request reprint Relationships between DVHs and late rectal bleeding after radiotherapy for prostate cancer: analysis of a large group of patients pooled from three institutions
    Claudio Fiorino
    Medical Physics Department, Ospedale San Raffaele, Milan, Italy
    Radiother Oncol 64:1-12. 2002
    ..e. DVH) as well as clinical information of large cohorts of patients. The possibility of collecting a large number of patients with many different dose-volume combinations is very suitable for this purpose...
  37. ncbi request reprint IMRT significantly reduces acute toxicity of whole-pelvis irradiation in patients treated with post-operative adjuvant or salvage radiotherapy after radical prostatectomy
    Filippo Alongi
    Department of Radiotherapy, Scientific Institute H San Raffaele, Milan, Italy
    Radiother Oncol 93:207-12. 2009
    ..To investigate the role of IMRT in reducing the risk of acute genito-urinary (GU), upper gastrointestinal (uGI) and lower gastrointestinal (lGI) toxicity following whole-pelvis irradiation (WPRT) after radical prostatectomy...
  38. ncbi request reprint Daily sodium butyrate enema for the prevention of radiation proctitis in prostate cancer patients undergoing radical radiation therapy: results of a multicenter randomized placebo-controlled dose-finding phase 2 study
    Angelo Maggio
    Medical Physics, San Raffaele Scientific Institute, Milan, Italy Electronic address
    Int J Radiat Oncol Biol Phys 89:518-24. 2014
    ..To evaluate the efficacy of sodium butyrate enemas (NABUREN) in prostate cancer radiation therapy (RT) in reducing the incidence, severity, and duration of acute RT-induced proctitis...
  39. doi request reprint Feasibility of an adaptive strategy in preoperative radiochemotherapy for rectal cancer with image-guided tomotherapy: boosting the dose to the shrinking tumor
    Paolo Passoni
    Department of Radiation Oncology, San Raffaele Scientific Institute, Milan, Italy
    Int J Radiat Oncol Biol Phys 87:67-72. 2013
    ..To investigate the feasibility of preoperative adaptive radiochemotherapy by delivering a concomitant boost to the residual tumor during the last 6 fractions of treatment...
  40. doi request reprint Is it time to tailor the prediction of radio-induced toxicity in prostate cancer patients? Building the first set of nomograms for late rectal syndrome
    Riccardo Valdagni
    Prostate Program, Scientific Directorate, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
    Int J Radiat Oncol Biol Phys 82:1957-66. 2012
    ..Development of user-friendly tools for the prediction of single-patient probability of late rectal toxicity after conformal radiotherapy for prostate cancer...
  41. doi request reprint Anatomical and clinical predictors of acute bowel toxicity in whole pelvis irradiation for prostate cancer with Tomotherapy
    Barbara Longobardi
    Medical Physics, San Raffaele Scientific Institute, Milan, Italy
    Radiother Oncol 101:460-4. 2011
    ..Assessing predictors of acute bowel toxicity after whole-pelvis irradiation (WPRT) Image-guided Tomotherapy with simultaneous integrated boost on prostate/prostate bed...
  42. ncbi request reprint Modeling set-up error by daily MVCT for prostate adjuvant treatment delivered in 20 fractions: Implications for the assessment of the optimal correction strategies
    Sara Broggi
    Medical Physics, IRCCS S Raffaele, Milano, Italy
    Radiother Oncol 93:246-52. 2009
    ..To optimise image-guided radiotherapy (IGRT) approaches in set-up error correction for hypofractionated adjuvant treatment of prostate cancer using helical tomotherapy (HT)...
  43. ncbi request reprint Rectum contouring variability in patients treated for prostate cancer: impact on rectum dose-volume histograms and normal tissue complication probability
    Claudio Fiorino
    Servizio di Fisica Sanitaria e Radiochemioterapia, H San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    Radiother Oncol 63:249-55. 2002
    ..However, no data are available about the possible impact of inter-institute variability in contouring the rectum, so that the possibility of reliably using information from single-centre studies remains doubtful...
  44. ncbi request reprint Significant reduction of acute toxicity following pelvic irradiation with helical tomotherapy in patients with localized prostate cancer
    Cesare Cozzarini
    Department of Radiotherapy, Scientific Institute H San Raffaele, 20132 Milan, Italy
    Radiother Oncol 84:164-70. 2007
    ..To assess and quantify the possible benefit deriving from IMRT with Helical Tomotherapy (HTT) delivery to the pelvic nodal area in patients with prostate cancer in terms of reduction of acute and late toxicities...
  45. ncbi request reprint Helical tomotherapy for scalp recurrence of primary eccrine mucinous adenocarcinoma
    Micaela Motta
    Radiotherapy Department, Scientific Institute San Raffaele, Milan, Italy
    Tumori 95:832-5. 2009
    ..This experience suggests a possible role of 18FDG-PET/CT-guided helical tomotherapy as an alternative to repeated and frequently demolitive surgery approaches...
  46. ncbi request reprint Rectal and bladder motion during conformal radiotherapy after radical prostatectomy
    Claudio Fiorino
    Servizio di Fisica Sanitaria, IRCCS H S Raffaele, Via Olgettina 60, 20132 Milano, Italy
    Radiother Oncol 74:187-95. 2005
    ..To investigate the extent and the impact of rectum and bladder motion during adjuvant conformal radiotherapy (3DCRT) after radical prostatectomy (RP)...
  47. doi request reprint Dose-volume and biological-model based comparison between helical tomotherapy and (inverse-planned) IMAT for prostate tumours
    Mauro Iori
    Department of Medical Physics, S Maria Nuova Hospital, Reggio Emilia, Italy
    Radiother Oncol 88:34-45. 2008
    ....
  48. ncbi request reprint Agreement criteria between expected and measured field fluences in IMRT of head and neck cancer: the importance and use of the gamma histograms statistical analysis
    Elena De Martin
    IRCCS San Raffaele, Via Olgettina 60, Milan, Italy
    Radiother Oncol 85:399-406. 2007
    ..The aim of this study was to analyse our pre-treatment QA data in order to establish uniquely defined agreement criteria between planned and delivered dose distribution for clinical QA practice in IMRT of head and neck (HN) patients...
  49. doi request reprint Megavoltage CT images of helical tomotherapy unit for radiation treatment simulation: impact on feasibility of treatment planning in a prostate cancer patient with bilateral femoral prostheses
    Filippo Alongi
    Radiotherapy and Radiosurgery Department, Humanitas Cancer Center, IRCCS Istituto ClinicoHumanitas, Rozzano, Milan, Italy
    Tumori 97:221-4. 2011
    ..Since there have been few reports on the use of MVCT images to overcome the problem of hip prosthesis artefacts, a brief literature review was also carried out...
  50. doi request reprint Feasibility of safe ultra-high (EQD(2)>100 Gy) dose escalation on dominant intra-prostatic lesions (DILs) by Helical Tomotheraphy
    Angelo Maggio
    Medical Physics, San Raffaele Scientific Institute, Milano, Italy
    Acta Oncol 50:25-34. 2011
    ..to verify the possibility of using Helical Tomotherapy to safely escalate dose to single or multiple highly radioresistant dominant intra-prostatic lesions (DILs) as assessed by functional magnetic resonance imaging (MRI)...
  51. ncbi request reprint [11C]choline-PET-guided helical tomotherapy and estramustine in a patient with pelvic-recurrent prostate cancer: local control and toxicity profile after 24 months
    Filippo Alongi
    Radiotherapy Department, San Raffaele Scientific Institute, Milan, Italy
    Tumori 96:613-7. 2010
    ..A disease-free survival of 24 months, in the absence of any type of systemic therapy, is uncommon in metastatic prostate cancer. The therapeutic approach of the case report is discussed and a literature review on the issue is presented...
  52. ncbi request reprint The impact of contouring uncertainty on rectal 3D dose-volume data: results of a dummy run in a multicenter trial (AIROPROS01-02)
    Franca Foppiano
    Department of Medical Physics, National Cancer Research Institute, Genova, Italy
    Int J Radiat Oncol Biol Phys 57:573-9. 2003
    ..To estimate the impact of the uncertainty in contouring the rectum on rectal dose-volume parameters and normal tissue complication probability (NTCP) in a prospective (AIROPROS01-02) investigation about rectal toxicity...
  53. doi request reprint Correlation between surrogates of bladder dosimetry and dose-volume histograms of the bladder wall defined on MRI in prostate cancer radiotherapy
    Viviana Carillo
    San Raffaele Scientific Institute, Milano, Italy
    Radiother Oncol 105:180-3. 2012
    ..DVH showed the poorest correlation with DWH; DSH or DVH-5/10 should be preferred in planning; absolute DVH may be used for radical patients, although less robust...
  54. doi request reprint Contouring variability of the penile bulb on CT images: quantitative assessment using a generalized concordance index
    Viviana Carillo
    Department of Medical Physics, San Raffaele Scientific Institute, Milano, Italy
    Int J Radiat Oncol Biol Phys 84:841-6. 2012
    ..The aim of this study was to quantitatively assess interobserver contouring variability by the application of the generalized DICE index...
  55. ncbi request reprint An automatic deformable registration method to evaluate parotid glands shrinkage during radiotherapy treatment in Tomotherapy
    Elena Faggiano
    Bioengineering Department, Politecnico di Milano, Milan, Italy
    Conf Proc IEEE Eng Med Biol Soc 2009:94-7. 2009
    ..1 mm from the external part toward the midline. The deformable registration method presented in this work provides an accurate tool for the automatic evaluation of parotid changes occurring during a radiotherapy treatment period...
  56. doi request reprint Long term rectal function after high-dose prostatecancer radiotherapy: results from a prospective cohort study
    Gianni Fellin
    Department of Radiotherapy, Ospedale Santa Chiara, Trento, Italy
    Radiother Oncol 110:272-7. 2014
    ..To prospectively evaluate long-term late rectal bleeding (lrb) and faecal incontinence (linc) after high-dose radiotherapy (RT) for prostate cancer in the AIROPROS 0102 population, and to assess clinical/dosimetric risk factors...
  57. ncbi request reprint Characterisation of rectal motion during neo-adjuvant radiochemotherapy for rectal cancer with image-guided tomotherapy: implications for adaptive dose escalation strategies
    Eleonora Maggiulli
    Medical Physics, San Raffaele Scientific Institute, Milano, Italy
    Acta Oncol 51:318-24. 2012
    ..Rectal motion remains a potentially important obstacle to the full exploitation of this approach and needs to be carefully investigated...
  58. ncbi request reprint Predictive models of toxicity with external radiotherapy for prostate cancer: clinical issues
    Riccardo Valdagni
    Prostate Program, Scientific Directorate, National Cancer Institute, Milan, Italy
    Cancer 115:3141-9. 2009
    ..Cancer 2009;115(13 suppl):3141-9. (c) 2009 American Cancer Society...
  59. doi request reprint NTCP modeling of subacute/late laryngeal edema scored by fiberoptic examination
    Tiziana Rancati
    Prostate Program, Istituto Nazionale dei Tumori, Milan, Italy
    Int J Radiat Oncol Biol Phys 75:915-23. 2009
    ..Finding best-fit parameters of normal tissue complication probability (NTCP) models for laryngeal edema after radiotherapy for head and neck cancer...
  60. ncbi request reprint Role of postoperative radiotherapy after pelvic lymphadenectomy and radical retropubic prostatectomy: a single institute experience of 415 patients
    Cesare Cozzarini
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    Int J Radiat Oncol Biol Phys 59:674-83. 2004
    ....
  61. doi request reprint Long-term biochemical control of prostate cancer after standard or hyper-fractionation: evidence for different outcomes between low-intermediate and high risk patients
    Riccardo Valdagni
    Prostate Program, Scientific Director s Office, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
    Radiother Oncol 101:454-9. 2011
    ..To report the long-term biochemical control of a non-randomized trial comparing standard (STD) and hyper-fractionated (HFX) radiation schedules for prostate cancer treatment...
  62. ncbi request reprint Relationships between bladder dose-volume/surface histograms and acute urinary toxicity after radiotherapy for prostate cancer
    Viviana Carillo
    Medical Physics, San Raffaele Scientific Institute, Milano, Italy
    Radiother Oncol 111:100-5. 2014
    ..35-2.7Gy/fr, HYPO). The current analysis focused on the relationship between bladder DVH/DSH and the risk of International Prostate Symptoms Score (IPSS)⩾15/20 at the end of radiotherapy...
  63. ncbi request reprint Inverse and forward optimization of one- and two-dimensional intensity-modulated radiation therapy-based treatment of concave-shaped planning target volumes: the case of prostate cancer
    Daniela Corletto
    Servizio di Fisica Sanitaria, H San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    Radiother Oncol 66:185-95. 2003
    ..However, up to now, few investigations tried to estimate the expected benefit with respect to conventional three-dimensional (3D) conformal radiotherapy (CRT)...
  64. ncbi request reprint Lethal pulmonary complications significantly correlate with individually assessed mean lung dose in patients with hematologic malignancies treated with total body irradiation
    Aldo Della Volpe
    Centro Trapianti di Midollo, Ospedale Maggiore di Milano IRCCS, Milano, Italy
    Int J Radiat Oncol Biol Phys 52:483-8. 2002
    ....
  65. doi request reprint Time course of hypothalamic-pituitary deficiency in adults receiving cranial radiotherapy for primary extrasellar brain tumors
    Sara Madaschi
    Endocrinology Unit, Department of Internal Medicine, San Raffaele Scientific Institute, Milan, Italy
    Radiother Oncol 99:23-8. 2011
    ..No longitudinal data on hypothalamic-pituitary (HP) function are available in patients who had received cranial radiation therapy (CRT) for primary extrasellar brain tumors (PBT)...
  66. ncbi request reprint Fractionation and late rectal toxicity: no reliable estimates of alpha/beta value for rectum can be derived from studies where different volumes of rectum are irradiated at different dose levels: in regard to Brenner (Int J Radiat Oncol Biol Phys 2004;60:
    Claudio Fiorino
    Int J Radiat Oncol Biol Phys 62:289-90; author reply 290-1. 2005
  67. ncbi request reprint Anatomic variations due to radical prostatectomy. Impact on target volume definition and dose-volume parameters of rectum and bladder
    Giuseppe Sanguineti
    Department of Radiation Oncology, University of Texas Medical Branch, Galveston, Texas 77555 0711, USA
    Strahlenther Onkol 180:563-72. 2004
    ..The purpose of this study was to investigate the impact of prostatectomy on the definition of CTV, on the position of bladder and rectum and their implications for three-dimensional conformal radiotherapy (3-D CRT)...
  68. ncbi request reprint Is the alpha-beta ratio of prostate cancer really low? A prospective, non-randomized trial comparing standard and hyperfractionated conformal radiation therapy
    Riccardo Valdagni
    Direzione Scientifica, Istituto Nazionale per la Cura e lo Studio dei Tumori, 20133 Milan, Italy
    Radiother Oncol 75:74-82. 2005
    ..0 Gy daily) (STD) or hyperfractionated (HFX) conformal irradiation (CRT). HFX (1.2 Gy BID) was chosen as a radiobiological method to try to reduce long term sequelae without compromising local control...
  69. ncbi request reprint Emptying the rectum before treatment delivery limits the variations of rectal dose - volume parameters during 3DCRT of prostate cancer
    Michele Stasi
    S C Fisica Sanitaria, Institute for Cancer Research and Treatment IRCC, Candiolo Torino, Italy
    Radiother Oncol 80:363-70. 2006
    ..To investigate the impact of rectum motion on dose - volume histograms of the rectum including filling and of the wall (DVH and DWH, respectively), during 3D-conformal radiotherapy (3DCRT) for localized prostate cancer...
  70. ncbi request reprint Dosimetric predictors of laryngeal edema
    Giuseppe Sanguineti
    Department of Radiation Oncology, University of Texas Medical Branch, Galveston, TX 77555 0711, USA
    Int J Radiat Oncol Biol Phys 68:741-9. 2007
    ..To investigate dosimetric predictors of laryngeal edema after radiotherapy (RT)...