Andres J M Ferreri

Summary

Affiliation: San Raffaele Scientific Institute
Country: Italy

Publications

  1. doi request reprint Primary CNS lymphoma
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Best Pract Res Clin Haematol 25:119-30. 2012
  2. doi request reprint How I treat primary CNS lymphoma
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Blood 118:510-22. 2011
  3. doi request reprint Marginal zone lymphomas and infectious agents
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, San Raffaele Scientific Institute, Milan, Italy Division of Onco Hematological Medicine, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy Electronic address
    Semin Cancer Biol 23:431-40. 2013
  4. doi request reprint The role of Helicobacter pylori eradication in the treatment of diffuse large B-cell and marginal zone lymphomas of the stomach
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Curr Opin Oncol 25:470-9. 2013
  5. doi request reprint Anaplastic large cell lymphoma, ALK-negative
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 85:206-15. 2013
  6. doi request reprint Anaplastic large cell lymphoma, ALK-positive
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 83:293-302. 2012
  7. doi request reprint Hepatosplenic gamma-delta T-cell lymphoma
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 83:283-92. 2012
  8. pmc Clinical relevance of the dose of cytarabine in the upfront treatment of primary CNS lymphomas with methotrexate-cytarabine combination
    Andres J M Ferreri
    Department of Oncology, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    Oncologist 16:336-41. 2011
  9. doi request reprint Enteropathy-associated T-cell lymphoma
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 79:84-90. 2011
  10. ncbi request reprint Bacteria-eradicating therapy with doxycycline in ocular adnexal MALT lymphoma: a multicenter prospective trial
    Andres J M Ferreri
    Medical Oncology Unit, Department of Oncology, San Raffaele H Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    J Natl Cancer Inst 98:1375-82. 2006

Detail Information

Publications70

  1. doi request reprint Primary CNS lymphoma
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Best Pract Res Clin Haematol 25:119-30. 2012
    ..Future therapeutic progresses in PCNSL will be based on the expansion of molecular and biological knowledge, the improvement of therapeutic efficacy and the prevention of iatrogenic neurotoxicity...
  2. doi request reprint How I treat primary CNS lymphoma
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Blood 118:510-22. 2011
    ..Herein, these important contributions are analyzed to provide recommendations for everyday practice and the rationale for future trials...
  3. doi request reprint Marginal zone lymphomas and infectious agents
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, San Raffaele Scientific Institute, Milan, Italy Division of Onco Hematological Medicine, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy Electronic address
    Semin Cancer Biol 23:431-40. 2013
    ..Biological and clinical features, therapeutic implications and future perspectives of these lymphoma-microbial associations are discussed in this review. ..
  4. doi request reprint The role of Helicobacter pylori eradication in the treatment of diffuse large B-cell and marginal zone lymphomas of the stomach
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Curr Opin Oncol 25:470-9. 2013
    ..This review is focused on the effect of Helicobacter pylori eradication with antibiotics in patients with primary gastric lymphomas of indolent and aggressive nature...
  5. doi request reprint Anaplastic large cell lymphoma, ALK-negative
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 85:206-15. 2013
    ....
  6. doi request reprint Anaplastic large cell lymphoma, ALK-positive
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 83:293-302. 2012
    ..Recently, the development of novel therapies targeting CD30 and ALK appear promising...
  7. doi request reprint Hepatosplenic gamma-delta T-cell lymphoma
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 83:283-92. 2012
    ..The use of 2'-deoxycoformycin and other targeted therapies, such as alemtuzumab, anti-γδ TCR monoclonal antibodies, and anti-CD44 therapy, have shown promising results in anecdotal reports...
  8. pmc Clinical relevance of the dose of cytarabine in the upfront treatment of primary CNS lymphomas with methotrexate-cytarabine combination
    Andres J M Ferreri
    Department of Oncology, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    Oncologist 16:336-41. 2011
    ..With respect to MTX-araC combination, araC dose was halved to minimize toxicity. Herein, we report tolerability, activity, and efficacy of MAT regimen and compare these results to those previously reported with MTX/ara-C combination...
  9. doi request reprint Enteropathy-associated T-cell lymphoma
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 79:84-90. 2011
    ..Moreover, the high incidence of severe postsurgical complications and the poor nutritional and immunological conditions lead to progressive deterioration of these patients, preventing the use of an adequate and effective treatment...
  10. ncbi request reprint Bacteria-eradicating therapy with doxycycline in ocular adnexal MALT lymphoma: a multicenter prospective trial
    Andres J M Ferreri
    Medical Oncology Unit, Department of Oncology, San Raffaele H Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    J Natl Cancer Inst 98:1375-82. 2006
    ..The effectiveness of doxycycline treatment in Cp-negative OAL has not been tested...
  11. doi request reprint Central nervous system dissemination in immunocompetent patients with aggressive lymphomas: incidence, risk factors and therapeutic options
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Oncology, San Raffaele H Scientific Institute, Milan, Italy
    Hematol Oncol 27:61-70. 2009
    ....
  12. ncbi request reprint Primary diffuse large B-cell lymphoma of the stomach
    Andres J M Ferreri
    Medical Oncology Unit, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 63:65-71. 2007
    ..Several questions on the best treatment remain unanswered. Among others, the role of rituximab, consolidation radiotherapy as well as of more conservative approaches like H. pylori-eradicating antibiotic therapy should be better defined...
  13. ncbi request reprint Re-occurrence of the CD20 molecule expression subsequent to CD20-negative relapse in diffuse large B-cell lymphoma
    A J Ferreri
    Medical Oncology Unit, Dept of Oncology, San Raffaele H Scientific Institute, Milan, Italy
    Haematologica 92:e1-2. 2007
    ..Accordingly, every relapse, whenever possible, should be histologically assessed with diagnostic and immunophenotyping purposes...
  14. ncbi request reprint Marginal-zone lymphoma
    Andres J M Ferreri
    Medical Oncology Unit, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 63:245-56. 2007
    ..However, prospective trials on these malignancies are rare and universally accepted therapeutic guidelines do not exist. MZLs constitute an exciting investigational setting both from molecular and clinical points of view...
  15. ncbi request reprint Primary central nervous system lymphoma
    Andres J M Ferreri
    Medical Oncology Unit, San Raffaele Scientific Institute, Milan, Italy
    Crit Rev Oncol Hematol 63:257-68. 2007
    ..Although studies published on PCNSL are increasing, several therapeutic questions still remain unanswered after a decade of research...
  16. doi request reprint Consolidation radiotherapy in primary central nervous system lymphomas: impact on outcome of different fields and doses in patients in complete remission after upfront chemotherapy
    Andrés José María Ferreri
    Unit of Lymphoid Malignancies, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Int J Radiat Oncol Biol Phys 80:169-75. 2011
    ..Nevertheless, no study has focused on the survival impact of radiation parameters, as far as we know, and the optimal radiation schedule remains to be defined...
  17. ncbi request reprint Ocular adnexal MALT lymphoma: an intriguing model for antigen-driven lymphomagenesis and microbial-targeted therapy
    A J M Ferreri
    Unit of Lymphoid Malignancies, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Ann Oncol 19:835-46. 2008
    ..In this review, we analyze the most relevant biological, molecular, pathological and clinical features of OAML and propose some therapeutic guidelines for patients affected by this malignancy...
  18. doi request reprint Chlamydophila psittaci is viable and infectious in the conjunctiva and peripheral blood of patients with ocular adnexal lymphoma: results of a single-center prospective case-control study
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, San Raffaele Scientific Institute, Milan, Italy
    Int J Cancer 123:1089-93. 2008
    ..Cp infection is common in OAML patients and exceptional in blood donors. Epidemiological data of OAML patients (prolonged contact with household animals and chronic conjunctivitis) are consistent with Cp exposure risk...
  19. doi request reprint Chlamydial infection: the link with ocular adnexal lymphomas
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, San Raffaele Scientific Institute, Milan, Italy
    Nat Rev Clin Oncol 6:658-69. 2009
    ..Available data on the epidemiology, biology and pathogenesis of this association are analyzed and new investigative and clinical approaches are discussed...
  20. doi request reprint High-dose chemotherapy supported by autologous stem cell transplantation in patients with primary central nervous system lymphoma: facts and opinions
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Medical Oncology Unit, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Leuk Lymphoma 49:2042-7. 2008
    ..This critical review is focused on the analysis of published experiences on HDC/ASCT in PCNSL in order to provide preliminary answers to the most pressing questions in this field...
  21. doi request reprint Infectious agents and lymphoma development: molecular and clinical aspects
    A J M Ferreri
    Unit of Lymphoid Malignancies, Medical Oncology Unit, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    J Intern Med 265:421-38. 2009
    ..Molecular, biological and clinical features as well as therapeutic implications of these associations are analysed and future perspectives in this field are discussed...
  22. doi request reprint High-dose cytarabine plus high-dose methotrexate versus high-dose methotrexate alone in patients with primary CNS lymphoma: a randomised phase 2 trial
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, San Raffaele Scientific Institute, Milan, Italy
    Lancet 374:1512-20. 2009
    ..We assessed the effect of adding high-dose cytarabine to methotrexate in patients with newly diagnosed primary CNS lymphoma...
  23. doi request reprint Intralesional rituximab: a new therapeutic approach for patients with conjunctival lymphomas
    Andres J M Ferreri
    Unit of Lymphoid Malignancies, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Ophthalmology 118:24-8. 2011
    ..Intralesional administration of this drug has increased local disease control in cases of cutaneous mucosa-associated lymphoid tissue (MALT) lymphoma...
  24. ncbi request reprint Hematologic malignancies: from clinical science to clinical practice - 2nd European Congress
    Andres J M Ferreri
    Medical Oncology Unit, San Raffaele H Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    IDrugs 9:242-6. 2006
  25. ncbi request reprint Clinical implications of hepatitis C virus infection in MALT-type lymphoma of the ocular adnexa
    A J M Ferreri
    Medical Oncology Unit, San Raffaele H Scientific Institute, Milan, Italy
    Ann Oncol 17:769-72. 2006
    ..A pathogenic link between hepatitis C virus (HCV) and MALT-type lymphomas has been suggested. However, studies assessing the role of HCV infection separately in different forms of MALT lymphomas are not available...
  26. ncbi request reprint Evidence for an association between Chlamydia psittaci and ocular adnexal lymphomas
    Andres J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    J Natl Cancer Inst 96:586-94. 2004
    ..Hence, we assessed whether Chlamydiae infection is associated with the development of ocular adnexal lymphomas...
  27. ncbi request reprint Summary statement on primary central nervous system lymphomas from the Eighth International Conference on Malignant Lymphoma, Lugano, Switzerland, June 12 to 15, 2002
    Andres J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Via Olgettina 60, 20132, Milan, Italy
    J Clin Oncol 21:2407-14. 2003
    ..This article summarizes the contents of the Workshop, analyzes the current knowledge on the most relevant biologic and clinical issues in PCNSL, and focuses on fundamental challenges to be addressed in future studies...
  28. ncbi request reprint Prognostic scoring system for primary CNS lymphomas: the International Extranodal Lymphoma Study Group experience
    Andres J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    J Clin Oncol 21:266-72. 2003
    ..To identify survival predictors and to design a prognostic score useful for distinguishing risk groups in immunocompetent patients with primary CNS lymphomas (PCNSL)...
  29. ncbi request reprint Consolidation radiotherapy to bulky or semibulky lesions in the management of stage III-IV diffuse large B cell lymphomas
    A J Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    Oncology 58:219-26. 2000
    ..To assess the impact on survival of consolidation radiotherapy to bulky or semibulky lesions in patients with advanced diffuse large B cell lymphoma (DLCL) in complete remission after primary chemotherapy...
  30. ncbi request reprint Relevance of intraocular involvement in the management of primary central nervous system lymphomas
    A J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    Ann Oncol 13:531-8. 2002
    ..Reported data regarding intraocular lymphoma (IOL) management are anecdotal. Cases of IOL included in an international multicentre series of 378 immunocompetent patients with primary central nervous system lymphomas (PCNSLs) were reviewed...
  31. ncbi request reprint A multicenter study of treatment of primary CNS lymphoma
    A J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    Neurology 58:1513-20. 2002
    ..To characterize the therapeutic variables correlated to outcome in 370 patients with primary CNS lymphoma...
  32. ncbi request reprint Anthracycline-based chemotherapy as primary treatment for intravascular lymphoma
    A J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    Ann Oncol 15:1215-21. 2004
    ..Optimal therapeutic management of intravascular lymphoma (IVL) lacks precise guidelines...
  33. ncbi request reprint Immunoreactivity for p27(KIP1) and cyclin E is an independent predictor of survival in primary gastric non-Hodgkin's lymphoma
    A J Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    Int J Cancer 94:599-604. 2001
    ..The predictive role of these molecules within each histologic group of PGLs deserves to be confirmed in larger series...
  34. ncbi request reprint Combined treatment with high-dose methotrexate, vincristine and procarbazine, without intrathecal chemotherapy, followed by consolidation radiotherapy for primary central nervous system lymphoma in immunocompetent patients
    A J Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    Oncology 60:134-40. 2001
    ..Patients who achieved a complete remission were referred to RT, those with progressive disease were excluded from further study; all the remaining patients received a third course of CHT followed by RT...
  35. ncbi request reprint Regression of ocular adnexal lymphoma after Chlamydia psittaci-eradicating antibiotic therapy
    Andres J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    J Clin Oncol 23:5067-73. 2005
    ..The present pilot study was carried out to assess whether C psittaci-eradicating antibiotic therapy is associated with tumor regression in ocular adnexal lymphomas...
  36. ncbi request reprint Therapeutic management of primary central nervous system lymphoma: lessons from prospective trials
    A J Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    Ann Oncol 11:927-37. 2000
    ..The assessment of impact of treatment on neuropsychological functions and quality of life is a mandatory endpoint in clinical trials...
  37. doi request reprint The addition of rituximab to anthracycline-based chemotherapy significantly improves outcome in 'Western' patients with intravascular large B-cell lymphoma
    Andres J M Ferreri
    Unit of Lymphoid Malignancies and Medical Oncology Unit, Department of Oncology, San Raffaele H Scientific Institute, Milano, Italy
    Br J Haematol 143:253-7. 2008
    ..50%; P = 0.04), event-free survival (3-year: 89% vs. 35%; P = 0.003) and overall survival (3-year: 89% vs. 38%; P = 0.01). In conclusion, rituximab may substantially change the dismal prognosis of IVL...
  38. doi request reprint Treatment approaches for primary CNS lymphomas
    Matteo G Carrabba
    San Raffaele Scientific Institute, Haematology and Bone Marrow Transplantation Unit, Department of Oncology, Milan, Italy
    Expert Opin Pharmacother 11:1263-76. 2010
    ..The overall outcome for PCNSL patients is unsatisfactory and several therapeutic questions remain open. Modest progress in outcome reflects difficulties in conducting randomized trials and scarce molecular and biological knowledge...
  39. doi request reprint Chlamydia infection and lymphomas: association beyond ocular adnexal lymphomas highlighted by multiple detection methods
    Maurilio Ponzoni
    Pathology Unit, San Raffaele Scientific Institute, Milano, Italy
    Clin Cancer Res 14:5794-800. 2008
    ..Herein, we used multiple Chlamydia detection tools to identify Cp elementary bodies-containing cell and to assess Cp prevalence in both nodal and extranodal lymphomas...
  40. ncbi request reprint Variations in clinical presentation, frequency of hemophagocytosis and clinical behavior of intravascular lymphoma diagnosed in different geographical regions
    Andres J M Ferreri
    Medical Oncology Unit, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Haematologica 92:486-92. 2007
    ..This study explored variations in the clinical manifestations of intravascular lymphoma (IVL) on the bases of the association with hemophagocytosis and the country where the diagnosis was made...
  41. ncbi request reprint Intravascular lymphoma: clinical presentation, natural history, management and prognostic factors in a series of 38 cases, with special emphasis on the 'cutaneous variant'
    Andres J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
    Br J Haematol 127:173-83. 2004
    ..ECOG-PS >1, 'cutaneous variant', stage I and chemotherapy use were independently associated with improved survival...
  42. ncbi request reprint Questions and answers in the management of primary central nervous system and ocular lymphomas
    Andres J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    Haematologica 88:1063-8. 2003
  43. doi request reprint Chlamydophila psittaci eradication with doxycycline as first-line targeted therapy for ocular adnexae lymphoma: final results of an international phase II trial
    Andres J M Ferreri
    San Raffaele Scientific Institute, Milan, Italy
    J Clin Oncol 30:2988-94. 2012
    ..To our knowledge, this is the first international phase II trial aimed at clarifying Cp prevalence and activity of first-line doxycycline in a homogeneous series of consecutive patients with newly diagnosed stage I OAMZL...
  44. ncbi request reprint Therapeutic management of ocular adnexal MALT lymphoma
    Andres J M Ferreri
    Medical Oncology Unit, Department of Oncology, San Raffaele Scientific Institute, Via Olgettina 6020132, Milan, Italy
    Expert Opin Pharmacother 8:1073-83. 2007
    ..In this review, the authors analyze related literature and propose therapeutic guidelines for the management of ocular adnexal lymphoma of MALT-type...
  45. pmc A reappraisal of the diagnostic and therapeutic management of uncommon histologies of primary ocular adnexal lymphoma
    Maurilio Ponzoni
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Oncologist 18:876-84. 2013
    ..This review covers the prevalence, clinical presentation, behavior, and histological and molecular features of uncommon forms of primary OAL and provides practical recommendations for therapeutic management. ..
  46. ncbi request reprint Intravascular lymphoma: a neoplasm of 'homeless' lymphocytes?
    Maurilio Ponzoni
    Pathology Unit, San Raffaele H Scientific Institute, Milan, Italy
    Hematol Oncol 24:105-12. 2006
    ..The present review will discuss the most recent acquisitions related either to diagnosis and immunophenotypic/biologic characteristics as well as clinical/therapeutic issues of IVL...
  47. pmc Prevalence of Borrelia burgdorferi infection in a series of 98 primary cutaneous lymphomas
    Maurilio Ponzoni
    Pathology Unit, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Oncologist 16:1582-8. 2011
    ..burgdorferi in primary cutaneous B- and T-cell lymphomas from areas nonendemic for this microorganism and the consequent rationale for the adoption of antibiotic therapy in these patients...
  48. ncbi request reprint Aberrant methylation in the promoter region of the reduced folate carrier gene is a potential mechanism of resistance to methotrexate in primary central nervous system lymphomas
    Andres J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    Br J Haematol 126:657-64. 2004
    ..If confirmed in prospective trials on PCNSL treated with HD-MTX alone, these data may suggest the necessity for alternative strategies in M-PCNSL considering the increased risk of MTX resistance by tumour cells...
  49. ncbi request reprint Definition, diagnosis, and management of intravascular large B-cell lymphoma: proposals and perspectives from an international consensus meeting
    Maurilio Ponzoni
    Unit of Lymphoma Malignancies, Pathology and Oncology Units, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    J Clin Oncol 25:3168-73. 2007
    ..Finally, a provisional practical diagnostic approach to hemophagocytosis-associated patients and a proposal for the most useful criteria in the settings of differential diagnosis are included...
  50. ncbi request reprint Prognostic value of bcl-6, CD10 and CD38 immunoreactivity in stage I-II gastric lymphomas: identification of a subset of CD10+ large B-cell lymphomas with a favorable outcome
    Maurilio Ponzoni
    Department of Pathology, San Raffaele H Scientific Institute, Milan, Italy
    Int J Cancer 106:288-91. 2003
    ..Accordingly, patients with CD10(+) gastric large B-cell lymphomas may be at reduced risk and eligible for clinical trials evaluating more conservative therapeutic options...
  51. ncbi request reprint Primary central nervous system lymphomas: salvage treatment after failure to high-dose methotrexate
    Michele Reni
    Medical Oncology Unit, Department of Oncology, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    Cancer Lett 258:165-70. 2007
    ..High-dose chemotherapy supported by stem cell autotransplant and intrathecal chemotherapy in meningeal failure have to be further investigated in prospective trials...
  52. ncbi request reprint Immunoreactivity for cyclin D3 is frequently detectable in high-grade primary gastric lymphomas in the absence of the t(6;14)(p21.1;q32.3) chromosomal translocation
    Giancarlo Pruneri
    Divisions of Pathology and Laboratory Medicine, European Institute of Oncology, Milan, Italy
    J Pathol 200:596-601. 2003
    ..000). These results suggest that the t(6;14) may represent a rare event in the pathogenesis of PGL and that cyclin D3 deregulation is most likely the result of epigenetic mechanisms...
  53. doi request reprint Central nervous system marginal zone B-cell lymphoma associated with Chlamydophila psittaci infection
    Maurilio Ponzoni
    Pathology Unit, San Raffaele Scientific Institute, 20132 Milan, Italy
    Hum Pathol 42:738-42. 2011
    ..This observation points toward the opportunity to investigate the prevalence of C psittaci infection in central nervous system lymphomas, particularly in those with low-grade histologic features...
  54. ncbi request reprint A virtual tissue bank for primary central nervous system lymphomas in immunocompetent individuals
    Maurilio Ponzoni
    Division of Pathology, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Pathobiology 74:264-9. 2007
    ..ielsg.org. Only anonymous data are centralized at the website of the International Extranodal Lymphoma Study Group, whilst the pathologic material is maintained at the local pathology institutes...
  55. ncbi request reprint Chronic idiopathic myelofibrosis: independent prognostic importance of bone marrow microvascular density evaluated by CD105 (endoglin) immunostaining
    Maurilio Ponzoni
    Department of Pathology, San Raffaele H Scientific Institute, Milan, Italy
    Mod Pathol 17:1513-20. 2004
    ..These findings provide a rationale for the investigational use of anti-CD105-targeted drugs in CIMF...
  56. ncbi request reprint Salvage chemotherapy with temozolomide in primary CNS lymphomas: preliminary results of a phase II trial
    Michele Reni
    Department of Radiochemotherapy, S Raffaele Hospital Scientific Institute, Milan, Italy
    Eur J Cancer 40:1682-8. 2004
    ..Although some patients had a poor PS and had been heavily pre-treated, temozolomide yielded 26% objective responses and was well tolerated without any major toxicity...
  57. doi request reprint Gastric lymphoma: the histology report
    Claudio Doglioni
    Department of Pathology, Scientific Institute San Raffaele, Milan, Italy
    Dig Liver Dis 43:S310-8. 2011
    ..This paper aims at giving the histopathologist a general knowledge about the state of art of this disease and its management. The diagnostic process leading to a complete and competent report is then described step by step...
  58. ncbi request reprint Prognostic factors in primary central nervous system lymphomas
    Andres J M Ferreri
    Medical Oncology Unit, Department of Oncology, San Raffaele H Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
    Hematol Oncol Clin North Am 19:629-49, vi. 2005
    ..In the years ahead, a well-established prognostic score will allow the separation of patients into risk groups, which could result in the application of risk-tailored therapeutic strategies...
  59. doi request reprint MATILDE chemotherapy regimen for primary CNS lymphoma: Results at a median follow-up of 12 years
    Andres J M Ferreri
    From the Unit of Lymphoid Malignancies A J M F, UTMO and Hematology Unit, Department of Onco Hematology F C, and Medical Oncology Unit, Department of Oncology M R, San Raffaele Scientific Institute, Milan Department of Medical Oncology A A B, Bellaria Maggiore Hospital, Azienda Unita Sanitaria Locale, Bologna Division of Hematology M M, Ospedale di Ancona Department of Medical Oncology and Hematology M B, Istituto Clinico Humanitas, Rozzano Division of Medical Oncology A M S, National Cancer Institute, Aviano Division of Hematology F I, Ospedale di Reggio Emilia Division of Hematology F Z, Ospedale di Udine Division of Hematology C S, Ospedale di Reggio Calabria Division of Hematology F B, Ospedale Maggiore di Novara Division of Hematology G C, Istituto Nazionale dei Tumori Pascale di Napoli and the Division of Hematology L B, Ospedale Maggiore di Milano, Italy
    Neurology 82:1370-3. 2014
    ..We report updated results at a median follow-up of 12 years of a phase II trial assessing first-line MATILDE chemotherapy and response-tailored radiotherapy in patients with primary CNS lymphomas (PCNSL)...
  60. doi request reprint Salvage chemoimmunotherapy with rituximab, ifosfamide and etoposide (R-IE regimen) in patients with primary CNS lymphoma relapsed or refractory to high-dose methotrexate-based chemotherapy
    Silvia Mappa
    Unit of Lymphoid Malignancies, Division of Onco Hematological Medicine, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy
    Hematol Oncol 31:143-50. 2013
    ..We concluded that R-IE is a feasible and active combination for patients with relapsed/refractory PCNSL. This regimen allows stem cell collection and successful consolidation with high-dose chemotherapy and autologous transplant...
  61. doi request reprint Clinical Features, Management, and Prognosis of an International Series of 161 Patients With Limited-Stage Diffuse Large B-Cell Lymphoma of the Bone (the IELSG-14 Study)
    Marta Bruno Ventre
    Unit of Lymphoid Malignancies, Department of Onco Hematology, San Raffaele Scientific Institute, Milan, Italy Department of Radiation Oncology, Princess Margaret Hospital, Ontario Cancer Institute, Toronto, Canada Auckland Hospital, Auckland, New Zealand Christie Hospital, Manchester, United Kingdom Seoul National University Hospital, Seoul, Korea Korea Cancer Center Hospital, Seoul, Korea Division of Hematology, European Institute of Oncology, Milan, Italy, Wesley Research Institute, Brisbane, Australia Northern Centre for Cancer, New Castle, United Kingdom Royal Prince Alfred Hospital, Sydney, Australia Oncology Institute of Southern Switzerland, Bellinzona, Switzerland Premion and Bond University, Tugun, Australia
    Oncologist 19:291-8. 2014
    ..In patients treated with chemoradiotherapy, the use of larger radiation fields and doses is not associated with better outcome. Central nervous system dissemination is a rare event in PB-DLBCL patients. ..
  62. doi request reprint Ocular adnexal lymphoma: diffusion-weighted mr imaging for differential diagnosis and therapeutic monitoring
    Letterio S Politi
    Department of Neuroradiology and Neuroradiology Research Unit, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy it
    Radiology 256:565-74. 2010
    ....
  63. doi request reprint Role of 18FDG-PET/CT in detecting relapse during follow-up of patients with Hodgkin's lymphoma
    R Crocchiolo
    Hematology and BMT Unit, San Raffaele Scientific Institute, Milan, Italy
    Ann Hematol 88:1229-36. 2009
    ..If FDG abnormal uptake is present at multiple nodal sites, subdiaphragmatic lymph nodes, or previous sites of disease, histological verification of PET abnormal findings is warranted...
  64. pmc Temozolomide as salvage treatment in primary brain lymphomas
    M Reni
    Medical Oncology Unit, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Br J Cancer 96:864-7. 2007
    ..Toxicity was negligible. We conclude that temozolomide is active in recurrent primary brain lymphomas and should further be evaluated in this disease, perhaps in combination with MTX as initial treatment...
  65. pmc Area under the curve of methotrexate and creatinine clearance are outcome-determining factors in primary CNS lymphomas
    A J M Ferreri
    Department of Radiochemotherapy, San Raffaele H Scientific Institute, Via Olgettina 60, Milan 20132, Italy
    Br J Cancer 90:353-8. 2004
    ..MTX dose adjustments in patients with fast CL(crea) should be investigated...
  66. ncbi request reprint Autoantibodies against a 72-kDa ductal cell membrane glycoprotein in a patient affected by Sjögren's syndrome and gastric MALT lymphoma
    F Folli
    Department of Medicine I, I R C C S H S Raffaele, Via Olgettina, 60, 20132 Milan, Italy
    Ann Hematol 81:597-602. 2002
    ..Autoantibodies directed against this novel membrane autoantigen may be an additional serological marker in some cases of Sjögren's syndrome...
  67. ncbi request reprint Primary brain CD30+ ALK1+ anaplastic large cell lymphoma ('ALKoma'): the first case with a combination of 'not common' variants
    M Ponzoni
    Departments of Pathology, S Raffaele H Scientific Institute, Milan, Italy
    Ann Oncol 13:1827-32. 2002
    ..The neuroimaging picture was not specific. A comparison with literature data concerning the clinical/instrumental features shows a very frequent meningeal involvement in PCNSL ALCLs, in contrast to the majority of PCNSLs...
  68. ncbi request reprint Reactive perivascular T-cell infiltrate predicts survival in primary central nervous system B-cell lymphomas
    M Ponzoni
    Pathology Unit, Unit of Lymphoid Malignancies, San Raffaele Scientific Institute, Milan, Italy
    Br J Haematol 138:316-23. 2007
    ..In conclusion, the presence of RPVI is independently associated with survival in PCNSL. This parameter can be easily and routinely assessed at diagnosis on histopathological specimens...
  69. ncbi request reprint MATILDE regimen followed by radiotherapy is an active strategy against primary CNS lymphomas
    A J M Ferreri
    Medical Oncology Unit, San Raffaele H Scientific Institute, Universita Vita Salute San Raffaele, Milan, Italy
    Neurology 66:1435-8. 2006
    ..Myelosuppression was the dose-limiting toxicity, with 9.5% of lethal complications. After a median follow-up of 49 months, a plateau in the survival curve (5-year overall survival: 41 +/- 7%) was obtained...
  70. doi request reprint Bone marrow histopathology in the diagnostic evaluation of splenic marginal-zone and splenic diffuse red pulp small B-cell lymphoma: a reliable substitute for spleen histopathology?
    Maurilio Ponzoni
    Pathology Unit, Department of Oncology, San Raffaele Scientific Institute, Milan, Italy
    Am J Surg Pathol 36:1609-18. 2012
    ..However, presently it is not possible to distinguish SMZL from SDRL on the basis of BMB evaluation alone; hence, histopathologic examination of the spleen remains the "gold standard" approach...