Giovanni Cazzaniga


Affiliation: San Gerardo Hospital
Country: Italy


  1. Fazio G, Massa V, Grioni A, Bystry V, Rigamonti S, Saitta C, et al. First evidence of a paediatric patient with Cornelia de Lange syndrome with acute lymphoblastic leukaemia. J Clin Pathol. 2019;: pubmed publisher
    ..A potential biological role of NIPBL in leukaemia has still to be dissected. ..
  2. Cazzaniga G, van Delft F, Lo Nigro L, Ford A, Score J, Iacobucci I, et al. Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemia. Blood. 2011;118:5559-64 pubmed publisher
    ..IKZF1 is a secondary and probable postnatal mutation in these cases, and as a recurrent but alternative copy number change is associated with poor prognosis. ..
  3. Cazzaniga G, de Lorenzo P, Alten J, Röttgers S, Hancock J, Saha V, et al. Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic l. Haematologica. 2018;103:107-115 pubmed publisher
    ..Early MRD negativity is highly predictive of favorable outcome. The earlier MRD negativity is achieved, the better the prognosis. ..