Mariangela Cavarelli

Summary

Affiliation: San Raffaele Scientific Institute
Country: Italy

Publications

  1. pmc HIV-1 co-receptor usage: influence on mother-to-child transmission and pediatric infection
    Mariangela Cavarelli
    Unit of Viral Evolution and Transmission, Division of Immunology, Transplant and Infectious Diseases, San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy
    J Transl Med 9:S10. 2011
  2. pmc R5 HIV-1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5
    Mariangela Cavarelli
    Unit of Viral Evolution and Transmission, DITID, San Raffaele Scientific Institute, Milan, Italy
    EMBO Mol Med 5:776-94. 2013
  3. pmc HIV-1 with multiple CCR5/CXCR4 chimeric receptor use is predictive of immunological failure in infected children
    Mariangela Cavarelli
    Viral Evolution and Transmission Unit, DIBIT, Fondazione Centro San Raffaele, Milan, Italy
    PLoS ONE 3:e3292. 2008
  4. pmc Phenotype variation in human immunodeficiency virus type 1 transmission and disease progression
    Mariangela Cavarelli
    Viral Evolution and Transmission Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
    Dis Markers 27:121-36. 2009
  5. doi request reprint Flexible use of CCR5 in the absence of CXCR4 use explains the immune deficiency in HIV-1 infected children
    Mariangela Cavarelli
    Viral Evolution and Transmission Unit, Division of Immunology, Transplantation and Infectious Diseases, DIBIT, San Raffaele Scientific Institute, Milan, Italy
    AIDS 24:2527-33. 2010
  6. ncbi request reprint Biological and genetic evolution of HIV type 1 in two siblings with different patterns of disease progression
    Chiara Ripamonti
    Viral Evolution and Transmission Unit, DIBIT, Fondazione Centro San Raffaele, Milan, Italy
    AIDS Res Hum Retroviruses 23:1531-40. 2007
  7. doi request reprint Unexpected dramatic increase in CD4+ cell count in a patient with AIDS after enfuvirtide treatment despite persistent viremia and resistance mutations
    Alessandro Soria
    Clinic of Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
    J Med Virol 80:937-41. 2008
  8. pmc Mn bioavailability by polarized Caco-2 cells: comparison between Mn gluconate and Mn oxyprolinate
    Chiara Foglieni
    Department of Human Morphology Città Studi, Universita degli Studi di Milano, Milan, Italy
    Nutr J 10:77. 2011
  9. doi request reprint HIV-derived vectors for gene therapy targeting dendritic cells
    Maura Rossetti
    San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, Milan, Italy
    Adv Exp Med Biol 762:239-61. 2013
  10. ncbi request reprint HIV-1 infection: the role of the gastrointestinal tract
    Mariangela Cavarelli
    Viral Evolution and Transmission Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
    Am J Reprod Immunol 71:537-42. 2014

Collaborators

Detail Information

Publications11

  1. pmc HIV-1 co-receptor usage: influence on mother-to-child transmission and pediatric infection
    Mariangela Cavarelli
    Unit of Viral Evolution and Transmission, Division of Immunology, Transplant and Infectious Diseases, San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy
    J Transl Med 9:S10. 2011
    ..Studies are needed to address more in specific the relevance of these factors in HIV-1 MTCT and pediatric infection of non-B subtypes...
  2. pmc R5 HIV-1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5
    Mariangela Cavarelli
    Unit of Viral Evolution and Transmission, DITID, San Raffaele Scientific Institute, Milan, Italy
    EMBO Mol Med 5:776-94. 2013
    ..Our findings indicate that HIV-1 translocation across the intestinal mucosa occurs through the selective engagement of DCs by R5 viruses, and may guide the design of new prevention strategies...
  3. pmc HIV-1 with multiple CCR5/CXCR4 chimeric receptor use is predictive of immunological failure in infected children
    Mariangela Cavarelli
    Viral Evolution and Transmission Unit, DIBIT, Fondazione Centro San Raffaele, Milan, Italy
    PLoS ONE 3:e3292. 2008
    ..Here, we ask the question whether phenotypic variation of R5 viruses could play a role also in mother-to-child transmission (MTCT) of HIV-1 and pediatric disease progression...
  4. pmc Phenotype variation in human immunodeficiency virus type 1 transmission and disease progression
    Mariangela Cavarelli
    Viral Evolution and Transmission Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
    Dis Markers 27:121-36. 2009
    ..Recent insights in the intrinsic variability of R5 viruses and their role in influencing disease progression in both adults and children are also discussed...
  5. doi request reprint Flexible use of CCR5 in the absence of CXCR4 use explains the immune deficiency in HIV-1 infected children
    Mariangela Cavarelli
    Viral Evolution and Transmission Unit, Division of Immunology, Transplantation and Infectious Diseases, DIBIT, San Raffaele Scientific Institute, Milan, Italy
    AIDS 24:2527-33. 2010
    ..The aim of the present work was to investigate viral phenotype variation during disease progression in HIV-1 infected children, six slow and eight fast progressors...
  6. ncbi request reprint Biological and genetic evolution of HIV type 1 in two siblings with different patterns of disease progression
    Chiara Ripamonti
    Viral Evolution and Transmission Unit, DIBIT, Fondazione Centro San Raffaele, Milan, Italy
    AIDS Res Hum Retroviruses 23:1531-40. 2007
    ..A marked viral genetic and phenotypic evolution was documented in the fast progressor sibling, which is accompanied by a high viral RANTES sensitivity and persistent neutralizing antibodies...
  7. doi request reprint Unexpected dramatic increase in CD4+ cell count in a patient with AIDS after enfuvirtide treatment despite persistent viremia and resistance mutations
    Alessandro Soria
    Clinic of Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
    J Med Virol 80:937-41. 2008
    ..A complex interplay of viral and host factors, including the control of X4 viruses and proviral burden, may favor immune restoration with HIV neutralizing activity, despite persistent viremia...
  8. pmc Mn bioavailability by polarized Caco-2 cells: comparison between Mn gluconate and Mn oxyprolinate
    Chiara Foglieni
    Department of Human Morphology Città Studi, Universita degli Studi di Milano, Milan, Italy
    Nutr J 10:77. 2011
    ..Manganese (Mn) is present in many enzymatic intracellular systems crucial for the regulation of cell metabolism, and is contained in commercially available metal supplements...
  9. doi request reprint HIV-derived vectors for gene therapy targeting dendritic cells
    Maura Rossetti
    San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, Milan, Italy
    Adv Exp Med Biol 762:239-61. 2013
    ..e., gene therapy strategies for monogenic diseases). In this chapter, similarities and differences between the LV-mediated and HIV-mediated induction of immune responses, with specific focus on their interactions with DC, are discussed...
  10. ncbi request reprint HIV-1 infection: the role of the gastrointestinal tract
    Mariangela Cavarelli
    Viral Evolution and Transmission Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
    Am J Reprod Immunol 71:537-42. 2014
    ..The understanding of these processes may help in developing efficient prevention strategies. ..
  11. ncbi request reprint Determination of HIV-1 co-receptor usage
    Mariangela Cavarelli
    Viral Evolution and Transmission Unit, Department of Immunology, Transplant, and Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
    Methods Mol Biol 1087:197-206. 2014
    ..Viral isolates can be phenotypically classified based on the co-receptor they utilize to infect target cells. In this chapter, methods to determine the co-receptor usage of HIV-1 variants are described. ..