Filippo Canducci

Summary

Affiliation: San Raffaele Scientific Institute
Country: Italy

Publications

  1. pmc Infection and coinfection of human rhinovirus C in stem cell transplant recipients
    Filippo Canducci
    Universita degli Studi dell Insubria, Via Ravasi 2, 21100 Varese, Italy
    Clin Dev Immunol 2013:236081. 2013
  2. pmc The role of infections and coinfections with newly identified and emerging respiratory viruses in children
    Maurizia Debiaggi
    Dipartimento di Scienze Clinico Chirurgiche, Diagnostiche e Pediatriche, Sezione di Microbiologia, 20132 Milan, Italy
    Virol J 9:247. 2012
  3. pmc Cross-reacting antibacterial auto-antibodies are produced within coronary atherosclerotic plaques of acute coronary syndrome patients
    Filippo Canducci
    Laboratory of Microbiology and Virology, Ospedale San Raffaele, Milan, Italy
    PLoS ONE 7:e42283. 2012
  4. ncbi Characterization of GBV-C infection in HIV-1 infected patients
    F Canducci
    San Raffaele Microbiology and Virology, Diagnostics and Research, Milan, Italy
    J Biol Regul Homeost Agents 17:191-4. 2003
  5. doi Dynamic patterns of human immunodeficiency virus type 1 integrase gene evolution in patients failing raltegravir-based salvage therapies
    Filippo Canducci
    Universita Vita Salute San Raffaele, Italy
    AIDS 23:455-60. 2009
  6. doi Genotypic/phenotypic patterns of HIV-1 integrase resistance to raltegravir
    Filippo Canducci
    Universita Vita Salute San Raffaele, Milano, Italy
    J Antimicrob Chemother 65:425-33. 2010
  7. doi Evolution patterns of raltegravir-resistant mutations after integrase inhibitor interruption
    F Canducci
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
    Clin Microbiol Infect 17:928-34. 2011
  8. doi The new and less toxic protease inhibitor saquinavir-NO maintains anti-HIV-1 properties in vitro indistinguishable from those of the parental compound saquinavir
    Filippo Canducci
    Laboratory of Virology and Microbiology, University Vita Salute San Raffaele, Milan, Italy
    Antiviral Res 91:292-5. 2011
  9. doi Cross-resistance profile of the novel integrase inhibitor Dolutegravir (S/GSK1349572) using clonal viral variants selected in patients failing raltegravir
    Filippo Canducci
    Vita Salute San Raffaele University, Laboratory of Virology and Microbiology, Milan, Italy
    J Infect Dis 204:1811-5. 2011
  10. pmc Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects
    Filippo Canducci
    Laboratorio di Microbiologia e Virologa, Universita Vita Salute San Raffaele, Milan, Italy
    Retrovirology 6:4. 2009

Detail Information

Publications30

  1. pmc Infection and coinfection of human rhinovirus C in stem cell transplant recipients
    Filippo Canducci
    Universita degli Studi dell Insubria, Via Ravasi 2, 21100 Varese, Italy
    Clin Dev Immunol 2013:236081. 2013
    ..In the same group of patients, the presence of other coinfecting respiratory pathogens, including the novel enterovirus 109, was also evaluated...
  2. pmc The role of infections and coinfections with newly identified and emerging respiratory viruses in children
    Maurizia Debiaggi
    Dipartimento di Scienze Clinico Chirurgiche, Diagnostiche e Pediatriche, Sezione di Microbiologia, 20132 Milan, Italy
    Virol J 9:247. 2012
    ..This review will present an overview of newly recognized as well as the main emerging respiratory viruses and seek to focus on the their contribution to infection and co-infection in LRTIs in childhood...
  3. pmc Cross-reacting antibacterial auto-antibodies are produced within coronary atherosclerotic plaques of acute coronary syndrome patients
    Filippo Canducci
    Laboratory of Microbiology and Virology, Ospedale San Raffaele, Milan, Italy
    PLoS ONE 7:e42283. 2012
    ..These findings demonstrated that in human atherosclerotic plaques a local cross-reactive immune response takes place...
  4. ncbi Characterization of GBV-C infection in HIV-1 infected patients
    F Canducci
    San Raffaele Microbiology and Virology, Diagnostics and Research, Milan, Italy
    J Biol Regul Homeost Agents 17:191-4. 2003
    ....
  5. doi Dynamic patterns of human immunodeficiency virus type 1 integrase gene evolution in patients failing raltegravir-based salvage therapies
    Filippo Canducci
    Universita Vita Salute San Raffaele, Italy
    AIDS 23:455-60. 2009
    ..Evaluate HIV-1 subtype B integrase gene evolution in patients failing raltegravir (RAL)-based savage regimens by clonal analysis of the replicating viral quasispecies...
  6. doi Genotypic/phenotypic patterns of HIV-1 integrase resistance to raltegravir
    Filippo Canducci
    Universita Vita Salute San Raffaele, Milano, Italy
    J Antimicrob Chemother 65:425-33. 2010
    ....
  7. doi Evolution patterns of raltegravir-resistant mutations after integrase inhibitor interruption
    F Canducci
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
    Clin Microbiol Infect 17:928-34. 2011
    ....
  8. doi The new and less toxic protease inhibitor saquinavir-NO maintains anti-HIV-1 properties in vitro indistinguishable from those of the parental compound saquinavir
    Filippo Canducci
    Laboratory of Virology and Microbiology, University Vita Salute San Raffaele, Milan, Italy
    Antiviral Res 91:292-5. 2011
    ....
  9. doi Cross-resistance profile of the novel integrase inhibitor Dolutegravir (S/GSK1349572) using clonal viral variants selected in patients failing raltegravir
    Filippo Canducci
    Vita Salute San Raffaele University, Laboratory of Virology and Microbiology, Milan, Italy
    J Infect Dis 204:1811-5. 2011
    ..However, viruses with mutation Q148R associated with secondary mutations and the combination Q148H+G140S were instead associated with a reduced level of susceptibility to dolutegravir in vitro...
  10. pmc Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects
    Filippo Canducci
    Laboratorio di Microbiologia e Virologa, Universita Vita Salute San Raffaele, Milan, Italy
    Retrovirology 6:4. 2009
    ..Overall, the data shown here documenting high selective pressure on the HIV-1 CD4bs of a group of LTNP subjects offers important insights for planning novel strategies for the immune control of HIV-1 infection...
  11. doi Two-year prospective study of single infections and co-infections by respiratory syncytial virus and viruses identified recently in infants with acute respiratory disease
    Filippo Canducci
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, and Istituto Scientifico San Raffaele, Milan, Italy
    J Med Virol 80:716-23. 2008
    ....
  12. ncbi Molecular cloning of the first human monoclonal antibodies neutralizing with high potency swine-origin influenza A pandemic virus (S-OIV)
    Roberto Burioni
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
    New Microbiol 32:319-24. 2009
    ..This is the first report of molecular cloning of human monoclonal antibodies against the new pandemic swine-origin influenza virus...
  13. pmc Epidemiological, molecular and clinical features of enterovirus 109 infection in children and in adult stem cell transplant recipients
    Maurizia Debiaggi
    Laboratory of Microbiology and Virology, San Raffaele Scientific Institute and Vita Salute, San Raffaele University, Milan, Italy
    Virol J 9:183. 2012
    ....
  14. ncbi Persistent symptomless human metapneumovirus infection in hematopoietic stem cell transplant recipients
    Maurizia Debiaggi
    Dipartimento di Scienze Morfologiche, Eidologiche e Cliniche, Sezione di Microbiologia, Universita di Pavia, via Brambilla, 74, 27100, Pavia, Italy
    J Infect Dis 194:474-8. 2006
    ..The data indicate that HSCT recipients may frequently develop symptomless hMPV infection...
  15. doi Monoclonal antibodies isolated from human B cells neutralize a broad range of H1 subtype influenza A viruses including swine-origin Influenza virus (S-OIV)
    Roberto Burioni
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    Virology 399:144-52. 2010
    ..Finally, the human genes coding for the neutralizing HMabs could be used for generating full human monoclonal IgGs that can be safely administered being potentially useful in the prophylaxis and the treatment of this human infection...
  16. doi Residual viraemia does not influence 1 year virological rebound in HIV-infected patients with HIV RNA persistently below 50 copies/mL
    Nicola Gianotti
    Department of Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
    J Antimicrob Chemother 67:213-7. 2012
    ..It is currently debated whether patients with residual viraemia are at higher risk of virological failure than those attaining <1 HIV RNA copy/mL. We therefore investigated the effect of residual viraemia on virological rebound...
  17. pmc Anti-HIV-1 response elicited in rabbits by anti-idiotype monoclonal antibodies mimicking the CD4-binding site
    Roberto Burioni
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Istituto Scientifico San Raffaele, Diagnostica e Ricerca San Raffaele, Milano, Italy
    PLoS ONE 3:e3423. 2008
    ....
  18. ncbi A phage display vector optimized for the generation of human antibody combinatorial libraries and the molecular cloning of monoclonal antibody fragments
    Laura Solforosi
    Laboratory of Microbiology and Virology, Vita Salute San Raffaele University, Milan, Italy
    New Microbiol 35:289-94. 2012
    ..The phagemid pCM was used to generate a human combinatorial phage display antibody library that allowed the selection of a monoclonal Fab fragment antibody directed against the nucleoprotein (NP) of Influenza A virus...
  19. doi In vitro phenotypes to elvitegravir and dolutegravir in primary macrophages and lymphocytes of clonal recombinant viral variants selected in patients failing raltegravir
    Filippo Canducci
    Department of Clinical and Experimental Medicine, Universita degli Studi dell Insubria, Varese, Italy
    J Antimicrob Chemother 68:2525-32. 2013
    ..Thus, a complete evaluation in parallel with all currently available integrase inhibitors (INIs) was performed...
  20. doi Antigen-driven evolution of B lymphocytes in coronary atherosclerotic plaques
    Roberto Burioni
    Universita Vita Salute San Raffaele, Milano, Italy
    J Immunol 183:2537-44. 2009
    ..The data document for the first time the presence of a local Ag-driven clonal evolution of B cells in human atherosclerotic plaques...
  21. ncbi Cloning and molecular characterization of a human recombinant IgG Fab binding to the Tat protein of human immunodeficiency virus type 1 (HIV-1) derived from the repertoire of a seronegative patient
    Nicasio Mancini
    Universita Vita Salute San Raffaele, San Raffaele Diagnostica e Ricerca, IRCCS Istituto Scientifico San Raffaele, Via Olgettina 60, 20132 Milano, Italy
    Mol Immunol 43:1363-9. 2006
    ....
  22. ncbi Quantitation of Bacillus clausii in biological samples by real-time polymerase chain reaction
    Mario Perotti
    Università Vita Salute San Raffaele and Laboratorio di Microbiologia e Virologia, Diagnostica e Ricerca San Raffaele, Milan, Italy
    J Microbiol Methods 65:632-6. 2006
    ..The quantitative assay showed a sensitivity level of 10(2) CFU/microl of sample. The method may represent a useful tool for monitoring the role of B. clausii as probiotic in vivo...
  23. doi Viral tropism by geno2pheno as a tool for predicting CD4 decrease in HIV-1-infected naive patients with high CD4 counts
    Silvia Nozza
    San Raffaele Scientific Institute, Milan, Italy
    J Antimicrob Chemother 67:1224-7. 2012
    ..To investigate the value of tropism (determined by genotypic testing) to predict CD4 depletion in HIV-infected antiretroviral-naive patients with high CD4 counts...
  24. pmc Use of genotype MTBDR assay for molecular detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis clinical strains isolated in Italy
    Paolo Miotto
    Emerging Bacterial Pathogens, San Raffaele Scientific Institute, Milan, Italy
    J Clin Microbiol 44:2485-91. 2006
    ..The MTBDR correctly identified the two cases of MDR-TB included in the panel. These results show that the MTBDR test is useful in the detection and management of tuberculosis when MDR disease is suspected...
  25. pmc Persistent replication of severe acute respiratory syndrome coronavirus in human tubular kidney cells selects for adaptive mutations in the membrane protein
    Filippo Pacciarini
    Viral Pathogens and Biosafety Unit, San Raffaele Scientific Institute, Milano, Italy
    J Virol 82:5137-44. 2008
    ..These findings indicate that human PTEC may represent a site of SARS-CoV productive and persistent replication favoring the emergence of viral variants with increased replication capacity, at least in these kidney cells...
  26. doi Raltegravir, maraviroc, etravirine: an effective protease inhibitor and nucleoside reverse transcriptase inhibitor-sparing regimen for salvage therapy in HIV-infected patients with triple-class experience
    Silvia Nozza
    Department of Infectious Diseases, San Raffaele Scientific Institute, Italy
    AIDS 24:924-8. 2010
    ..Although long-term safety needs further study, this protease inhibitor and nucleoside analogue-sparing regimen showed sustained efficacy...
  27. ncbi Evolutionary characteristics of HIV type 1 variants resistant to protease inhibitors in the absence of drug-selective pressure
    Enzo Boeri
    Diagnostica and Ricerca San Raffaele, Laoratorio di Virologia, Centro San Luigi, I R C C S Istituto Scientifico San Raffaele, 20 20127 Milan, Italy
    AIDS Res Hum Retroviruses 19:1151-3. 2003
    ....
  28. pmc Coronaviridae and SARS-associated coronavirus strain HSR1
    Elisa Vicenzi
    P2 P3 Laboratories, DIBIT, San Raffaele Scientific Institute, Via Olgettina n 58, 20132 Milan, Italy
    Emerg Infect Dis 10:413-8. 2004
    ..Overall, the molecular and biologic characteristics of the strain HSR1 provide evidence that SARS-CoV forms a fourth genetic coronavirus group with distinct genomic and biologic features...
  29. ncbi GB virus C and survival in persons with HIV infection
    Filippo Canducci
    N Engl J Med 350:2617-8; author reply 2617-8. 2004
  30. ncbi Long-term study on symptomless human metapneumovirus infection in hematopoietic stem cell transplant recipients
    Maurizia Debiaggi
    Dipartimento Scienze Morfologiche Eidologiche e Cliniche, Sezione Microbiologia, Universita di Pavia, Italy
    New Microbiol 30:255-8. 2007
    ..In addition, data collected suggest a hospital origin of hMPV infection in most HSCT patients during the 2004-2005 period...