Research Topics
| Filippo CanducciSummaryAffiliation: San Raffaele Scientific Institute Country: Italy Publications
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Detail Information
Publications
Infection and coinfection of human rhinovirus C in stem cell transplant recipientsFilippo Canducci
Universita degli Studi dell Insubria, Via Ravasi 2, 21100 Varese, Italy
Clin Dev Immunol 2013:236081. 2013..In the same group of patients, the presence of other coinfecting respiratory pathogens, including the novel enterovirus 109, was also evaluated...
The role of infections and coinfections with newly identified and emerging respiratory viruses in childrenMaurizia Debiaggi
Dipartimento di Scienze Clinico Chirurgiche, Diagnostiche e Pediatriche, Sezione di Microbiologia, 20132 Milan, Italy
Virol J 9:247. 2012..This review will present an overview of newly recognized as well as the main emerging respiratory viruses and seek to focus on the their contribution to infection and co-infection in LRTIs in childhood...
Cross-reacting antibacterial auto-antibodies are produced within coronary atherosclerotic plaques of acute coronary syndrome patientsFilippo Canducci
Laboratory of Microbiology and Virology, Ospedale San Raffaele, Milan, Italy
PLoS ONE 7:e42283. 2012..These findings demonstrated that in human atherosclerotic plaques a local cross-reactive immune response takes place...
Dynamic patterns of human immunodeficiency virus type 1 integrase gene evolution in patients failing raltegravir-based salvage therapiesFilippo Canducci
Universita Vita Salute San Raffaele, Italy
AIDS 23:455-60. 2009..Evaluate HIV-1 subtype B integrase gene evolution in patients failing raltegravir (RAL)-based savage regimens by clonal analysis of the replicating viral quasispecies...
Characterization of GBV-C infection in HIV-1 infected patientsF Canducci
San Raffaele Microbiology and Virology, Diagnostics and Research, Milan, Italy
J Biol Regul Homeost Agents 17:191-4. 2003....
Genotypic/phenotypic patterns of HIV-1 integrase resistance to raltegravirFilippo Canducci
Universita Vita Salute San Raffaele, Milano, Italy
J Antimicrob Chemother 65:425-33. 2010....
Evolution patterns of raltegravir-resistant mutations after integrase inhibitor interruptionF Canducci
Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
Clin Microbiol Infect 17:928-34. 2011....
The new and less toxic protease inhibitor saquinavir-NO maintains anti-HIV-1 properties in vitro indistinguishable from those of the parental compound saquinavirFilippo Canducci
Laboratory of Virology and Microbiology, University Vita Salute San Raffaele, Milan, Italy
Antiviral Res 91:292-5. 2011....
Cross-resistance profile of the novel integrase inhibitor Dolutegravir (S/GSK1349572) using clonal viral variants selected in patients failing raltegravirFilippo Canducci
Vita Salute San Raffaele University, Laboratory of Virology and Microbiology, Milan, Italy
J Infect Dis 204:1811-5. 2011..However, viruses with mutation Q148R associated with secondary mutations and the combination Q148H+G140S were instead associated with a reduced level of susceptibility to dolutegravir in vitro...
Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjectsFilippo Canducci
Laboratorio di Microbiologia e Virologa, Universita Vita Salute San Raffaele, Milan, Italy
Retrovirology 6:4. 2009..Overall, the data shown here documenting high selective pressure on the HIV-1 CD4bs of a group of LTNP subjects offers important insights for planning novel strategies for the immune control of HIV-1 infection...
Two-year prospective study of single infections and co-infections by respiratory syncytial virus and viruses identified recently in infants with acute respiratory diseaseFilippo Canducci
Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, and Istituto Scientifico San Raffaele, Milan, Italy
J Med Virol 80:716-23. 2008....
Molecular cloning of the first human monoclonal antibodies neutralizing with high potency swine-origin influenza A pandemic virus (S-OIV)Roberto Burioni
Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
New Microbiol 32:319-24. 2009..This is the first report of molecular cloning of human monoclonal antibodies against the new pandemic swine-origin influenza virus...
Epidemiological, molecular and clinical features of enterovirus 109 infection in children and in adult stem cell transplant recipientsMaurizia Debiaggi
Laboratory of Microbiology and Virology, San Raffaele Scientific Institute and Vita Salute, San Raffaele University, Milan, Italy
Virol J 9:183. 2012....
Monoclonal antibodies isolated from human B cells neutralize a broad range of H1 subtype influenza A viruses including swine-origin Influenza virus (S-OIV)Roberto Burioni
Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Via Olgettina 60, 20132 Milan, Italy
Virology 399:144-52. 2010..Finally, the human genes coding for the neutralizing HMabs could be used for generating full human monoclonal IgGs that can be safely administered being potentially useful in the prophylaxis and the treatment of this human infection...
Residual viraemia does not influence 1 year virological rebound in HIV-infected patients with HIV RNA persistently below 50 copies/mLNicola Gianotti
Department of Infectious Diseases, San Raffaele Scientific Institute, Milan, Italy
J Antimicrob Chemother 67:213-7. 2012..It is currently debated whether patients with residual viraemia are at higher risk of virological failure than those attaining <1 HIV RNA copy/mL. We therefore investigated the effect of residual viraemia on virological rebound...
Anti-HIV-1 response elicited in rabbits by anti-idiotype monoclonal antibodies mimicking the CD4-binding siteRoberto Burioni
Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Istituto Scientifico San Raffaele, Diagnostica e Ricerca San Raffaele, Milano, Italy
PLoS ONE 3:e3423. 2008....
Antigen-driven evolution of B lymphocytes in coronary atherosclerotic plaquesRoberto Burioni
Universita Vita Salute San Raffaele, Milano, Italy
J Immunol 183:2537-44. 2009..The data document for the first time the presence of a local Ag-driven clonal evolution of B cells in human atherosclerotic plaques...
A phage display vector optimized for the generation of human antibody combinatorial libraries and the molecular cloning of monoclonal antibody fragmentsLaura Solforosi
Laboratory of Microbiology and Virology, Vita Salute San Raffaele University, Milan, Italy
New Microbiol 35:289-94. 2012..The phagemid pCM was used to generate a human combinatorial phage display antibody library that allowed the selection of a monoclonal Fab fragment antibody directed against the nucleoprotein (NP) of Influenza A virus...
Viral tropism by geno2pheno as a tool for predicting CD4 decrease in HIV-1-infected naive patients with high CD4 countsSilvia Nozza
San Raffaele Scientific Institute, Milan, Italy
J Antimicrob Chemother 67:1224-7. 2012..To investigate the value of tropism (determined by genotypic testing) to predict CD4 depletion in HIV-infected antiretroviral-naive patients with high CD4 counts...
Use of genotype MTBDR assay for molecular detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis clinical strains isolated in ItalyPaolo Miotto
Emerging Bacterial Pathogens, San Raffaele Scientific Institute, Milan, Italy
J Clin Microbiol 44:2485-91. 2006..The MTBDR correctly identified the two cases of MDR-TB included in the panel. These results show that the MTBDR test is useful in the detection and management of tuberculosis when MDR disease is suspected...
Persistent replication of severe acute respiratory syndrome coronavirus in human tubular kidney cells selects for adaptive mutations in the membrane proteinFilippo Pacciarini
Viral Pathogens and Biosafety Unit, San Raffaele Scientific Institute, Milano, Italy
J Virol 82:5137-44. 2008..These findings indicate that human PTEC may represent a site of SARS-CoV productive and persistent replication favoring the emergence of viral variants with increased replication capacity, at least in these kidney cells...
Raltegravir, maraviroc, etravirine: an effective protease inhibitor and nucleoside reverse transcriptase inhibitor-sparing regimen for salvage therapy in HIV-infected patients with triple-class experienceSilvia Nozza
Department of Infectious Diseases, San Raffaele Scientific Institute, Italy
AIDS 24:924-8. 2010..Although long-term safety needs further study, this protease inhibitor and nucleoside analogue-sparing regimen showed sustained efficacy...
Coronaviridae and SARS-associated coronavirus strain HSR1Elisa Vicenzi
P2 P3 Laboratories, DIBIT, San Raffaele Scientific Institute, Via Olgettina n 58, 20132 Milan, Italy
Emerg Infect Dis 10:413-8. 2004..Overall, the molecular and biologic characteristics of the strain HSR1 provide evidence that SARS-CoV forms a fourth genetic coronavirus group with distinct genomic and biologic features...
Evolutionary characteristics of HIV type 1 variants resistant to protease inhibitors in the absence of drug-selective pressureEnzo Boeri
Diagnostica and Ricerca San Raffaele, Laoratorio di Virologia, Centro San Luigi, I R C C S Istituto Scientifico San Raffaele, 20 20127 Milan, Italy
AIDS Res Hum Retroviruses 19:1151-3. 2003....
Quantitation of Bacillus clausii in biological samples by real-time polymerase chain reactionMario Perotti
Università Vita Salute San Raffaele and Laboratorio di Microbiologia e Virologia, Diagnostica e Ricerca San Raffaele, Milan, Italy
J Microbiol Methods 65:632-6. 2006..The quantitative assay showed a sensitivity level of 10(2) CFU/microl of sample. The method may represent a useful tool for monitoring the role of B. clausii as probiotic in vivo...
GB virus C and survival in persons with HIV infectionFilippo Canducci
N Engl J Med 350:2617-8; author reply 2617-8. 2004
Persistent symptomless human metapneumovirus infection in hematopoietic stem cell transplant recipientsMaurizia Debiaggi
Dipartimento di Scienze Morfologiche, Eidologiche e Cliniche, Sezione di Microbiologia, Universita di Pavia, via Brambilla, 74, 27100, Pavia, Italy
J Infect Dis 194:474-8. 2006..The data indicate that HSCT recipients may frequently develop symptomless hMPV infection...
Long-term study on symptomless human metapneumovirus infection in hematopoietic stem cell transplant recipientsMaurizia Debiaggi
Dipartimento Scienze Morfologiche Eidologiche e Cliniche, Sezione Microbiologia, Universita di Pavia, Italy
New Microbiol 30:255-8. 2007..In addition, data collected suggest a hospital origin of hMPV infection in most HSCT patients during the 2004-2005 period...
Cloning and molecular characterization of a human recombinant IgG Fab binding to the Tat protein of human immunodeficiency virus type 1 (HIV-1) derived from the repertoire of a seronegative patientNicasio Mancini
, San Raffaele Diagnostica e Ricerca, IRCCS Istituto Scientifico San Raffaele, Via Olgettina 60, 20132 Milano, Italy
Mol Immunol 43:1363-9. 2006....
