Roberto Burioni

Summary

Affiliation: San Raffaele Scientific Institute
Country: Italy

Publications

  1. ncbi Anti-HIV-1 response elicited in rabbits by anti-idiotype monoclonal antibodies mimicking the CD4-binding site
    Roberto Burioni
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Istituto Scientifico San Raffaele, Diagnostica e Ricerca San Raffaele, Milano, Italy
    PLoS ONE 3:e3423. 2008
  2. ncbi Monoclonal antibodies isolated from human B cells neutralize a broad range of H1 subtype influenza A viruses including swine-origin Influenza virus (S-OIV)
    Roberto Burioni
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    Virology 399:144-52. 2010
  3. ncbi Molecular cloning of the first human monoclonal antibodies neutralizing with high potency swine-origin influenza A pandemic virus (S-OIV)
    Roberto Burioni
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
    New Microbiol 32:319-24. 2009
  4. ncbi Hepatitis C virus (HCV) infection may elicit neutralizing antibodies targeting epitopes conserved in all viral genotypes
    Nicasio Mancini
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italia
    PLoS ONE 4:e8254. 2009
  5. ncbi Hepatitis C virus (HCV)-driven stimulation of subfamily-restricted natural IgM antibodies in mixed cryoglobulinemia
    Mario Perotti
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milan, Italy
    Autoimmun Rev 7:468-72. 2008
  6. ncbi Neutralization activity and kinetics of two broad-range human monoclonal IgG1 derived from recombinant Fab fragments and directed against Hepatitis C Virus E2 glycoprotein
    Roberta Antonia Diotti
    Laboratory of Microbiology and Virology, Universit Vita Salute San Raffaele, Milano, Italy
    New Microbiol 35:475-9. 2012
  7. ncbi Anti-hepatitis C virus E2 (HCV/E2) glycoprotein monoclonal antibodies and neutralization interference
    Giuseppe Sautto
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
    Antiviral Res 96:82-9. 2012
  8. ncbi Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects
    Filippo Canducci
    Laboratorio di Microbiologia e Virologa, Universita Vita Salute San Raffaele, Milan, Italy
    Retrovirology 6:4. 2009
  9. ncbi HCV proteins and immunoglobulin variable gene (IgV) subfamilies in HCV-induced type II mixed cryoglobulinemia: a concurrent pathogenetic role
    Giuseppe Sautto
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Via Olgettina, 58, 20132 Milano, Italy
    Clin Dev Immunol 2012:705013. 2012
  10. ncbi Development and validation of a molecular method for the diagnosis of medically important fungal infections
    Donata De Marco
    Laboratorio di Microbiologia e Virologia, Diagnostica e Ricerca San Raffaele, Milano
    New Microbiol 30:308-12. 2007

Collaborators

Detail Information

Publications22

  1. ncbi Anti-HIV-1 response elicited in rabbits by anti-idiotype monoclonal antibodies mimicking the CD4-binding site
    Roberto Burioni
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Istituto Scientifico San Raffaele, Diagnostica e Ricerca San Raffaele, Milano, Italy
    PLoS ONE 3:e3423. 2008
    ....
  2. ncbi Monoclonal antibodies isolated from human B cells neutralize a broad range of H1 subtype influenza A viruses including swine-origin Influenza virus (S-OIV)
    Roberto Burioni
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Via Olgettina 60, 20132 Milan, Italy
    Virology 399:144-52. 2010
    ..Finally, the human genes coding for the neutralizing HMabs could be used for generating full human monoclonal IgGs that can be safely administered being potentially useful in the prophylaxis and the treatment of this human infection...
  3. ncbi Molecular cloning of the first human monoclonal antibodies neutralizing with high potency swine-origin influenza A pandemic virus (S-OIV)
    Roberto Burioni
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
    New Microbiol 32:319-24. 2009
    ..This is the first report of molecular cloning of human monoclonal antibodies against the new pandemic swine-origin influenza virus...
  4. ncbi Hepatitis C virus (HCV) infection may elicit neutralizing antibodies targeting epitopes conserved in all viral genotypes
    Nicasio Mancini
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italia
    PLoS ONE 4:e8254. 2009
    ..Their availability may open new avenues to the understanding of HCV persistence and to the development of strategies for the immune control of this infection...
  5. ncbi Hepatitis C virus (HCV)-driven stimulation of subfamily-restricted natural IgM antibodies in mixed cryoglobulinemia
    Mario Perotti
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milan, Italy
    Autoimmun Rev 7:468-72. 2008
    ..An antigen-driven stimulation of these subfamilies, and their overexpression as in HCV infection, could lead to a breaking of humoral homeostatic balance exposing the patients to the risk of developing autoimmune disorders...
  6. ncbi Neutralization activity and kinetics of two broad-range human monoclonal IgG1 derived from recombinant Fab fragments and directed against Hepatitis C Virus E2 glycoprotein
    Roberta Antonia Diotti
    Laboratory of Microbiology and Virology, Universit Vita Salute San Raffaele, Milano, Italy
    New Microbiol 35:475-9. 2012
    ..This paper describes the very high neutralization activity and unique biological features of two broadly cross-reactive and cross-neutralizing anti-HCV human monoclonal IgG1 derived from human monoclonal recombinant Fab fragments...
  7. ncbi Anti-hepatitis C virus E2 (HCV/E2) glycoprotein monoclonal antibodies and neutralization interference
    Giuseppe Sautto
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
    Antiviral Res 96:82-9. 2012
    ..Overall, a better comprehension of this phenomenon may be of importance in the set up of novel mAb-based anti-HCV therapeutic strategies...
  8. ncbi Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects
    Filippo Canducci
    Laboratorio di Microbiologia e Virologa, Universita Vita Salute San Raffaele, Milan, Italy
    Retrovirology 6:4. 2009
    ..Overall, the data shown here documenting high selective pressure on the HIV-1 CD4bs of a group of LTNP subjects offers important insights for planning novel strategies for the immune control of HIV-1 infection...
  9. ncbi HCV proteins and immunoglobulin variable gene (IgV) subfamilies in HCV-induced type II mixed cryoglobulinemia: a concurrent pathogenetic role
    Giuseppe Sautto
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Via Olgettina, 58, 20132 Milano, Italy
    Clin Dev Immunol 2012:705013. 2012
    ..In this paper, we analyze both the humoral and viral counterparts at the basis of cryoglobulins production in HCV-induced MCII, with particular attention reserved to the single IgV subfamilies most frequently involved...
  10. ncbi Development and validation of a molecular method for the diagnosis of medically important fungal infections
    Donata De Marco
    Laboratorio di Microbiologia e Virologia, Diagnostica e Ricerca San Raffaele, Milano
    New Microbiol 30:308-12. 2007
    ....
  11. ncbi Identification of a broadly cross-reacting and neutralizing human monoclonal antibody directed against the hepatitis C virus E2 protein
    Mario Perotti
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, DIBIT2, Via Olgettina 60, 20132 Milano, Italia
    J Virol 82:1047-52. 2008
    ..Fab e137 was also able to inhibit cell culture-grown HCV (genotype 2a). These data indicate that broadly cross-reacting and cross-neutralizing antibodies are generated during HCV infection...
  12. ncbi A human monoclonal antibody with neutralizing activity against highly divergent influenza subtypes
    Nicola Clementi
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italia
    PLoS ONE 6:e28001. 2011
    ..A deep characterization of PN-SIA28 features may represent a useful help in the improvement of available anti-influenza therapeutic strategies and can provide new tools for the development of universal vaccinal strategies...
  13. ncbi Antigen-driven evolution of B lymphocytes in coronary atherosclerotic plaques
    Roberto Burioni
    Universita Vita Salute San Raffaele, Milano, Italy
    J Immunol 183:2537-44. 2009
    ..The data document for the first time the presence of a local Ag-driven clonal evolution of B cells in human atherosclerotic plaques...
  14. ncbi Cloning and molecular characterization of a human recombinant IgG Fab binding to the Tat protein of human immunodeficiency virus type 1 (HIV-1) derived from the repertoire of a seronegative patient
    Nicasio Mancini
    , San Raffaele Diagnostica e Ricerca, IRCCS Istituto Scientifico San Raffaele, Via Olgettina 60, 20132 Milano, Italy
    Mol Immunol 43:1363-9. 2006
    ....
  15. ncbi Quantitation of Bacillus clausii in biological samples by real-time polymerase chain reaction
    Mario Perotti
    Università Vita Salute San Raffaele and Laboratorio di Microbiologia e Virologia, Diagnostica e Ricerca San Raffaele, Milan, Italy
    J Microbiol Methods 65:632-6. 2006
    ..The quantitative assay showed a sensitivity level of 10(2) CFU/microl of sample. The method may represent a useful tool for monitoring the role of B. clausii as probiotic in vivo...
  16. ncbi Modulation of epitope-specific anti-hepatitis C virus E2 (anti-HCV/E2) antibodies by anti-viral treatment
    Nicasio Mancini
    Laboratorio di Microbiologia, , Istituto Scientifico San Raffaele, Milano, Italy
    J Med Virol 78:1304-11. 2006
    ....
  17. ncbi The era of molecular and other non-culture-based methods in diagnosis of sepsis
    Nicasio Mancini
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Diagnostica e Ricerca San Raffaele, Milano, Italia
    Clin Microbiol Rev 23:235-51. 2010
    ..In particular, the potential clinical role for the sensitive and rapid detection of bacterial and fungal DNA in the development of new diagnostic algorithms is discussed...
  18. ncbi Potential role of the detection of enterobacterial DNA in blood for the management of neonatal necrotizing enterocolitis
    Nicasio Mancini
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
    J Med Microbiol 61:1465-72. 2012
    ....
  19. ncbi A potential role for monoclonal antibodies in prophylactic and therapeutic treatment of influenza
    Nicasio Mancini
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
    Antiviral Res 92:15-26. 2011
    ..In this review, all major monoclonal antibodies directed against different influenza virus proteins are reported and their potential in the design of new anti-influenza prophylactic or therapeutic strategies is discussed...
  20. ncbi Molecular diagnosis of sepsis in neutropenic patients with haematological malignancies
    Nicasio Mancini
    Laboratorio di Microbiologia e Virologia, Universita Vita Salute San Raffaele, Milano, Italy
    J Med Microbiol 57:601-4. 2008
    ..Overall, the characteristics featured by the molecular method could be of interest in the development of new algorithms for the diagnosis of sepsis in critical patients...
  21. ncbi Rapid molecular identification of fungal pathogens in corneal samples from suspected keratomycosis cases
    Nicasio Mancini
    Laboratorio di Microbiologia e Virologia1, Dipartimento di Oftalmologia e Scienze della Visione, IRCCS Istituto Scientifico San Raffaele, Milan, Italy
    J Med Microbiol 55:1505-9. 2006
    ..Similar studies on larger panels of patients and on different clinical samples are required for further investigation of the clinical potential of ITS-based approaches in the diagnosis of mycotic infections...
  22. ncbi Direct sequencing of Scedosporium apiospermum DNA in the diagnosis of a case of keratitis
    Nicasio Mancini
    Laboratorio di Microbiologia, Diagnostica e Ricerca San Raffaele and Centro Malattie della Cornea, Dipartimento di Oftalmologia e Scienze della Visione, IRCCS Istituto Scientifico San Raffaele, Via Olgettina 60, 20132 Milano, Italy
    J Med Microbiol 54:897-900. 2005
    ..The data highlight the diagnostic role of molecular techniques, in parallel with conventional methods, in the management of ocular infections of fungal aetiology...