Renato A Sinico

Summary

Affiliation: Renal Immunopathology Center
Country: Italy

Publications

  1. ncbi request reprint Azathioprine hypersensitivity: report of two cases and review of the literature
    Renato A Sinico
    Unit of Nephrology and Dialysis, Center of Clinical Immunology and Rheumatology, San Carlo Borromeo Hospital, Via Pio Secondo 3, 20153 Milan, Italy
    J Nephrol 16:272-6. 2003
  2. ncbi request reprint Anti-C1q autoantibodies in lupus nephritis: prevalence and clinical significance
    Renato Alberto Sinico
    Dipartimento di Nefrologia e Immunologia, Azienda Ospedaliera, Ospedale San Carlo Borromeo, Via Pio Secondo 3, 20153 Milano, Italy
    Ann N Y Acad Sci 1050:193-200. 2005
  3. ncbi request reprint Prevalence and clinical significance of antineutrophil cytoplasmic antibodies in Churg-Strauss syndrome
    Renato A Sinico
    Dipartimento di Nefrologia e Immunologia, Azienda Ospedaliera Ospedale San Carlo Borromeo, Milan, Italy
    Arthritis Rheum 52:2926-35. 2005
  4. ncbi request reprint Renal involvement in Churg-Strauss syndrome
    Renato Alberto Sinico
    Dipartimento Area Medica, Azienda Ospedaliera Ospedale San Carlo Borromeo, Milan, Italy
    Am J Kidney Dis 47:770-9. 2006
  5. ncbi request reprint Value of a new automated fluorescence immunoassay (EliA) for PR3 and MPO-ANCA in monitoring disease activity in ANCA-associated systemic vasculitis
    Renato Alberto Sinico
    Dipartimento di Nefrologia e Immunologia, Azienda Ospedaliera, Ospedale San Carlo Borromeo, Via Pio Secondo 3, 20153 Milano, Italy
    Ann N Y Acad Sci 1050:185-92. 2005
  6. ncbi request reprint [New insights in the treatment of ANCA-associated systemic vasculitis]
    R A Sinico
    UOS di Immunologia Clinica, Dipartimento Area medica e Dipartimento di Nefrologia e Immunologia, Azienda Ospedaliera Ospedale San Carlo Borromeo, Milano, Italy
    G Ital Nefrol 23:138-48. 2006
  7. ncbi request reprint [Interdisciplinary Forum on Autoimmune Disease Research: guidelines]
    Renato Alberto Sinico
    Unità Operativa di Nefrologia e Centro di Immunologia Clinica e Reumatologia Azienda Ospedaliera Ospedale San Carlo Borromeo, Via Pio II, 3, 20153 Milano, Italy
    G Ital Nefrol 19:212-24. 2002
  8. ncbi request reprint The use of laboratory tests in diagnosis and monitoring of systemic lupus erythematosus
    Renato Alberto Sinico
    Nephrology and Dialysis Unit and Center of Clinical Immunology and Rheumatology, San Carlo Borromeo Hospital, Milan, Italy
    J Nephrol 15:S20-7. 2002
  9. ncbi request reprint [ANCA-associated vasculitis]
    R A Sinico
    Unita Operativa di Nefrologia e Centro di Immunologia Clinica e Reumatologia, Milano, Italy
    G Ital Nefrol 19:125-36. 2002
  10. ncbi request reprint [The clinical immunology laboratory in diagnosis and monitoring of systemic lupus erythematosus and connective tissue diseases]
    R A Sinico
    Unita Operativa di Immunologia Clinica, Azienda Ospedaliera, Ospedale San Carlo Borromeo, Milano
    G Ital Nefrol 22:S21-6. 2005

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Azathioprine hypersensitivity: report of two cases and review of the literature
    Renato A Sinico
    Unit of Nephrology and Dialysis, Center of Clinical Immunology and Rheumatology, San Carlo Borromeo Hospital, Via Pio Secondo 3, 20153 Milan, Italy
    J Nephrol 16:272-6. 2003
    ....
  2. ncbi request reprint Anti-C1q autoantibodies in lupus nephritis: prevalence and clinical significance
    Renato Alberto Sinico
    Dipartimento di Nefrologia e Immunologia, Azienda Ospedaliera, Ospedale San Carlo Borromeo, Via Pio Secondo 3, 20153 Milano, Italy
    Ann N Y Acad Sci 1050:193-200. 2005
    ..Our results confirm that anti-C1q antibodies are present in a significant percentage of SLE patients, and that their presence and levels correlate with disease activity-in particular, during renal flare-ups...
  3. ncbi request reprint Prevalence and clinical significance of antineutrophil cytoplasmic antibodies in Churg-Strauss syndrome
    Renato A Sinico
    Dipartimento di Nefrologia e Immunologia, Azienda Ospedaliera Ospedale San Carlo Borromeo, Milan, Italy
    Arthritis Rheum 52:2926-35. 2005
    ..We undertook this study to examine the prevalence and antigen specificity of ANCAs in a large cohort of patients with CSS. Moreover, we evaluated the relationship between ANCA positivity and clinicopathologic features...
  4. ncbi request reprint Renal involvement in Churg-Strauss syndrome
    Renato Alberto Sinico
    Dipartimento Area Medica, Azienda Ospedaliera Ospedale San Carlo Borromeo, Milan, Italy
    Am J Kidney Dis 47:770-9. 2006
    ..Renal involvement is not regarded as a prominent feature, and its prevalence and severity vary widely in published reports that usually refer to small series of selected patients...
  5. ncbi request reprint Value of a new automated fluorescence immunoassay (EliA) for PR3 and MPO-ANCA in monitoring disease activity in ANCA-associated systemic vasculitis
    Renato Alberto Sinico
    Dipartimento di Nefrologia e Immunologia, Azienda Ospedaliera, Ospedale San Carlo Borromeo, Via Pio Secondo 3, 20153 Milano, Italy
    Ann N Y Acad Sci 1050:185-92. 2005
    ..We recommend that ANCA titer be used to monitor AASV disease activity with the caveat that a few exceptions, in particular with MPO-ANCA, are possible...
  6. ncbi request reprint [New insights in the treatment of ANCA-associated systemic vasculitis]
    R A Sinico
    UOS di Immunologia Clinica, Dipartimento Area medica e Dipartimento di Nefrologia e Immunologia, Azienda Ospedaliera Ospedale San Carlo Borromeo, Milano, Italy
    G Ital Nefrol 23:138-48. 2006
    ....
  7. ncbi request reprint [Interdisciplinary Forum on Autoimmune Disease Research: guidelines]
    Renato Alberto Sinico
    Unità Operativa di Nefrologia e Centro di Immunologia Clinica e Reumatologia Azienda Ospedaliera Ospedale San Carlo Borromeo, Via Pio II, 3, 20153 Milano, Italy
    G Ital Nefrol 19:212-24. 2002
  8. ncbi request reprint The use of laboratory tests in diagnosis and monitoring of systemic lupus erythematosus
    Renato Alberto Sinico
    Nephrology and Dialysis Unit and Center of Clinical Immunology and Rheumatology, San Carlo Borromeo Hospital, Milan, Italy
    J Nephrol 15:S20-7. 2002
    ..Among biological parameters, urinary levels of monocyte chemoattranct protein 1 (MCP1) seem to be the most useful to monitor nephritis activity in lupus patients...
  9. ncbi request reprint [ANCA-associated vasculitis]
    R A Sinico
    Unita Operativa di Nefrologia e Centro di Immunologia Clinica e Reumatologia, Milano, Italy
    G Ital Nefrol 19:125-36. 2002
    ..When serum creatinine is than 500 ml/L (5.6 mg/dl) and/or oliguria is present, the addition of methylprednisolone pulses and/or plasma exchange should be considered...
  10. ncbi request reprint [The clinical immunology laboratory in diagnosis and monitoring of systemic lupus erythematosus and connective tissue diseases]
    R A Sinico
    Unita Operativa di Immunologia Clinica, Azienda Ospedaliera, Ospedale San Carlo Borromeo, Milano
    G Ital Nefrol 22:S21-6. 2005
    ..New assays (anti-C1q and anti-nucleosome antibodies) have been recently proposed for the diagnosis (anti-nucleosome) and monitoring of SLE patients (anti-C1q and anti-nucleosome antibodies), with promising results...
  11. doi request reprint Churg-Strauss angiitis
    Renato A Sinico
    Clinical Immunology Unit and Renal Unit, Department of Medicine, Azienda Ospedaliera Ospedale San Carlo Borromeo, Milano, Italy
    Best Pract Res Clin Rheumatol 23:355-66. 2009
    ..The length of the maintenance therapy remains to be established. However, the vast majority of patients require long-term corticosteroids treatment to control asthma...
  12. doi request reprint Renal involvement in anti-neutrophil cytoplasmic autoantibody associated vasculitis
    Renato A Sinico
    Clinical Immunology Unit and Renal Unit, Department of Medicine, Azienda Ospedaliera Ospedale San Carlo Borromeo, Via Pio Secondo, 3, 20153 Milano, Italy
    Autoimmun Rev 12:477-82. 2013
    ....
  13. ncbi request reprint A new oligonucleotide-based ELISA for the detection of anti-double-stranded DNA antibodies
    Antonella Radice
    Azienda Ospedaliera Ospedale San Carlo Borromeo, Unita Operativa di Immunologia Clinica, Dipartimento Area Medica, Milano, Italy
    Autoimmunity 39:113-9. 2006
    ..59, p < 0.0001). In conclusion, this assay has proved to be reproducible, and the results correlate well with other standard anti-dsDNA assays. The features of this new assay make it promising for clinical use...
  14. ncbi request reprint Early response to immunosuppressive therapy predicts good renal outcome in lupus nephritis: lessons from long-term followup of patients in the Euro-Lupus Nephritis Trial
    Frédéric A Houssiau
    Universite Catholique de Louvain, Brussels, Belgium
    Arthritis Rheum 50:3934-40. 2004
    ..After a median followup of 41 months, a difference in efficacy between the 2 regimens was not observed. The present analysis was undertaken to extend the followup and to identify prognostic factors...
  15. doi request reprint Antinucleosome antibodies in primary antiphospholipid syndrome: a hint at systemic autoimmunity?
    Laura Andreoli
    Rheumatology and Clinical Immunology Unit, Spedali Civili, Piazzale Spedali Civili 1, University of Brescia, 25123 Brescia, Italy
    J Autoimmun 30:51-7. 2008
    ..Patients with primary antiphospholipid syndrome (PAPS) may develop full-blown SLE but there is no evidence for markers predictive for that...
  16. ncbi request reprint Immunosuppressive therapy in lupus nephritis: the Euro-Lupus Nephritis Trial, a randomized trial of low-dose versus high-dose intravenous cyclophosphamide
    Frédéric A Houssiau
    Cliniques Universitaires St Luc, Universite Catholique de Louvain, Brussels, Belgium
    Arthritis Rheum 46:2121-31. 2002
    ..Given the side effects of this regimen, we evaluated the efficacy and the toxicity of a course of low-dose IV CYC prescribed as a remission-inducing treatment, followed by azathioprine (AZA) as a remission-maintaining treatment...
  17. ncbi request reprint Autoantibodies to proteinase 3 and myeloperoxidase in systemic sclerosis
    Amelia Ruffatti
    Department of Medical and Surgical Sciences, University of Padova, Italy
    J Rheumatol 29:918-23. 2002
    ..We evaluated the prevalence and clinical significance of proteinase 3 (PR3-) and myeloperoxidase (MPO-) antineutrophil cytoplasmic antibodies (ANCA) in 115 patients with systemic sclerosis (SSc, scleroderma)...