Research Topics
Genomes and Genes | M P RastaldiSummaryAffiliation: Renal Immunopathology Center Country: Italy Publications
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Detail Information
Publications
Patterns of nephrin and a new proteinuria-associated protein expression in human renal diseasesShi-xuan Wang
Department of Bacteriology and Immunology, Haartman Institute and University Central Hospital, University of Helsinki, Helsinki, Finland
Kidney Int 61:141-7. 2002....
Glomerular monocyte-macrophage features in ANCA-positive renal vasculitis and cryoglobulinemic nephritisM P Rastaldi
Renal Immunopathology Center, San Carlo Borromeo Hospital, Milan, Italy
J Am Soc Nephrol 11:2036-43. 2000..Moreover, acute activation and cytokine production seem to be present in a greater number of macrophages in ANCA + RV, giving this disease a stronger severity that could be taken into account for therapeutic strategies...
Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsiesMaria P Rastaldi
Renal Research Association, Renal Immunopathology Centre, San Carlo Borromeo Hospital, Via Pio II, 3, 20153 Milan, Italy
Kidney Int 62:137-46. 2002..According to this theory, they should proceed through several activating steps, such as proliferation and phenotype changes, to eventually synthesize extracellular matrix (ECM)...
Glomerular podocytes possess the synaptic vesicle molecule Rab3A and its specific effector rabphilin-3aMaria Pia Rastaldi
Renal Immunopathology Laboratory, Associazione Nuova Nefrologia, c o San Carlo Borromeo Hospital, Via Pio II, 20153 Milan, Italy
Am J Pathol 163:889-99. 2003..The altered expression observed in mouse and human proteinuric diseases suggests a possible role for these molecules in glomerulopathies...
Idiopathic IgA nephropathy with segmental necrotizing lesions of the capillary wallG D'Amico
Division of Nephrology, San Carlo Borromeo Hospital, Milan, Italy
Kidney Int 59:682-92. 2001....
Histopathological atlas of renal diseases: anti-glomerular basement membrane antibody diseaseF Ferrario
Renal Immunopathology Center, S Carlo Borromeo Hospital and Nuova Nefrologia Research Association, Milan Italy
J Nephrol 18:351-3. 2005..By light microscopy several histological patterns can be observed...
Glomerular clusterin is associated with PKC-alpha/beta regulation and good outcome of membranous glomerulonephritis in humansM P Rastaldi
Renal Immunopathology Laboratory, Fondazione D Amico per la Ricerca sulle Malattie Renali, Nuova Nefrologia Research Association, c o San Carlo Borromeo Hospital, Milan, Italy
Kidney Int 70:477-85. 2006..Binding of clusterin to the LDL-R might offer an interpretative key for the pathogenesis of MGN in humans...
Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathyMaja T Lindenmeyer
Nephrologisches Zentrum, Medizinische Poliklinik, University of Munich, Pettenkoferstrasse 8a, 80336 Munich, Germany
J Am Soc Nephrol 18:1765-76. 2007..These findings and the questions about rodent models in DN raise a note of caution regarding the proposal to inhibit VEGF-A to prevent progression of DN...
Induction of TRPC6 channel in acquired forms of proteinuric kidney diseaseClemens C Möller
Department of Medicine, Nephrology Division, Massachusetts General Hospital and Harvard Medical School, MGH East, 149 13th Street, Boston, MA 02129, USA
J Am Soc Nephrol 18:29-36. 2007..These studies suggest the involvement of TRPC6 in the pathology of nongenetic forms of proteinuric disease...
Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosisChiraz El-Aouni
Division of Nephrology, Department of Internal Medicine, University of Michigan, 1570 MSRB II, 1150 W Medical Center Drive, Ann Arbor, MI 48109 0676, USA
J Am Soc Nephrol 17:1334-44. 2006....
CD20-positive infiltrates in human membranous glomerulonephritisClemens D Cohen
Medizinische Poliklinik, Nephrologisches Zentrum, Ludwig-Maximilians-University, Munich, Germany
J Nephrol 18:328-33. 2005....
Sam68-like mammalian protein 2, identified by digital differential display as expressed by podocytes, is induced in proteinuria and involved in splice site selection of vascular endothelial growth factorClemens D Cohen
Medizinische Poliklinik, Ludwig Maximilians University, Pettenkoferstrasse 8a, Munich, 80336, Germany
J Am Soc Nephrol 16:1958-65. 2005..SLM-2-dependent VEGF splicing indicates the importance of mRNA splice site selection for glomerular filtration barrier function...
Proteinuria and hyperglycemia induce endoplasmic reticulum stressMaja T Lindenmeyer
Nephrology Center, Medizinische Poliklinik, University of Munich, Munich, Germany
J Am Soc Nephrol 19:2225-36. 2008..Although this may protect the cells from ER stress, persistence of hyperglycemia and proteinuria may eventually lead to apoptosis...
