Oreste Segatto

Summary

Affiliation: Regina Elena Cancer Institute
Country: Italy

Publications

  1. doi request reprint Regulation of epidermal growth factor receptor signalling by inducible feedback inhibitors
    Oreste Segatto
    Department of Experimental Oncology, Regina Elena Cancer Institute, 00158 Rome, Italy
    J Cell Sci 124:1785-93. 2011
  2. ncbi request reprint Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin
    Sergio Anastasi
    Laboratory of Immunology, Regina Elena Cancer Institute, Via delle Messi d oro, 156 158, 00158, Rome, Italy
    Oncogene 24:4540-8. 2005
  3. ncbi request reprint Feedback inhibition by RALT controls signal output by the ErbB network
    Sergio Anastasi
    Regina Elena Cancer Institute, Via delle Messi d oro, 156, Rome 00158, Italy
    Oncogene 22:4221-34. 2003

Collaborators

  • Sigurdur Ingvarsson
  • Sergio Anastasi
  • Gianluca Sala
  • Stefano Iacovelli
  • Elisabetta Caprini
  • Fabiana Lucini
  • Chen Huiping
  • Giandomenico Russo
  • L Castellani
  • Maurizio Alimandi
  • Rocco Fraioli
  • Stefano Alema
  • Loredana Fiorentino
  • Monia Fiorini

Detail Information

Publications3

  1. doi request reprint Regulation of epidermal growth factor receptor signalling by inducible feedback inhibitors
    Oreste Segatto
    Department of Experimental Oncology, Regina Elena Cancer Institute, 00158 Rome, Italy
    J Cell Sci 124:1785-93. 2011
    ..Finally, we discuss how IFIs might participate in system control of EGFR signalling and highlight the emerging roles for IFIs in the suppression of EGFR-driven tumorigenesis...
  2. ncbi request reprint Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin
    Sergio Anastasi
    Laboratory of Immunology, Regina Elena Cancer Institute, Via delle Messi d oro, 156 158, 00158, Rome, Italy
    Oncogene 24:4540-8. 2005
    ..Thus, loss of RALT expression cooperates with ERBB2 gene amplification to drive full oncogenic signalling by the ErbB-2 receptor. Moreover, loss of RALT signalling may adversely affect tumor responses to ErbB-2-targeting agents...
  3. ncbi request reprint Feedback inhibition by RALT controls signal output by the ErbB network
    Sergio Anastasi
    Regina Elena Cancer Institute, Via delle Messi d oro, 156, Rome 00158, Italy
    Oncogene 22:4221-34. 2003
    ..We propose that quantitative and qualitative aspects of RALT signalling concur in defining identity, strength and duration of signals generated by the ErbB network...