A Pace

Summary

Affiliation: Regina Elena Cancer Institute
Country: Italy

Publications

  1. ncbi request reprint Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response
    A Pace
    Department of Neuroscience, Regina Elena National Cancer Institute, Rome, Italy
    Ann Oncol 14:1722-6. 2003
  2. ncbi request reprint Vitamin E for prophylaxis against chemotherapy-induced neuropathy: a randomized controlled trial
    Andrea Pace
    Neurology 65:501-2; author reply 501-2. 2005
  3. pmc Early perfusion changes in patients with recurrent high-grade brain tumor treated with Bevacizumab: preliminary results by a quantitative evaluation
    Antonello Vidiri
    Radiology and Diagnostic Imaging Department, Regina Elena Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy
    J Exp Clin Cancer Res 31:33. 2012
  4. pmc Improving neuro-oncological patients care: basic and practical concepts for nurse specialist in neuro-rehabilitation
    Michelangelo Bartolo
    Neurorehabilitation Unit, IRCCS Neuromed, Mediterranean Neurological Institute, Pozzilli, Isernia, Italy
    J Exp Clin Cancer Res 31:82. 2012
  5. doi request reprint Epilepsy in the end-of-life phase in patients with high-grade gliomas
    Andrea Pace
    Palliative Home Care Unit for Brain Tumor Patients, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy
    J Neurooncol 111:83-6. 2013
  6. pmc Brain metastases from solid tumors: disease outcome according to type of treatment and therapeutic resources of the treating center
    Alessandra Fabi
    Department of Medical Oncology, Regina Elena National Cancer Institute, Rome Italy
    J Exp Clin Cancer Res 30:10. 2011
  7. pmc The role side effects play in the choice of antiepileptic therapy in brain tumor-related epilepsy: a comparative study on traditional antiepileptic drugs versus oxcarbazepine
    Marta Maschio
    Center for Tumor related Epilepsy, Department of Neuroscience and Cervical Facial Pathology, National Institute for Cancer Regina Elena, Via Elio Chianesi 53, 00144 Roma, Italy
    J Exp Clin Cancer Res 28:60. 2009
  8. pmc Quantitative analysis of CT-perfusion parameters in the evaluation of brain gliomas and metastases
    Anna Maria Di Nallo
    Regina Elena National Cancer Institute, Rome, Italy
    J Exp Clin Cancer Res 28:38. 2009
  9. pmc Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation
    Alessandra Fabi
    Division of Medical Oncology, Regina Elena Cancer Institute, Rome, Italy
    BMC Cancer 9:101. 2009
  10. doi request reprint End of life issues in brain tumor patients
    Andrea Pace
    Department of Neuroscience, Palliative Home Care Unit for Brain Tumor Patients, Regina Elena National Cancer Institute, Via Chianesi 53, Rome, 00144, Italy
    J Neurooncol 91:39-43. 2009

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response
    A Pace
    Department of Neuroscience, Regina Elena National Cancer Institute, Rome, Italy
    Ann Oncol 14:1722-6. 2003
    ..The optimal treatment for low-grade glioma (LGG) is still controversial. Recent data indicate a potential influence of chemotherapy on the natural evolution of these tumors, allowing for the deferral of more aggressive therapies...
  2. ncbi request reprint Vitamin E for prophylaxis against chemotherapy-induced neuropathy: a randomized controlled trial
    Andrea Pace
    Neurology 65:501-2; author reply 501-2. 2005
  3. pmc Early perfusion changes in patients with recurrent high-grade brain tumor treated with Bevacizumab: preliminary results by a quantitative evaluation
    Antonello Vidiri
    Radiology and Diagnostic Imaging Department, Regina Elena Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy
    J Exp Clin Cancer Res 31:33. 2012
    ....
  4. pmc Improving neuro-oncological patients care: basic and practical concepts for nurse specialist in neuro-rehabilitation
    Michelangelo Bartolo
    Neurorehabilitation Unit, IRCCS Neuromed, Mediterranean Neurological Institute, Pozzilli, Isernia, Italy
    J Exp Clin Cancer Res 31:82. 2012
    ..The purpose of the study is to identify the standard competencies for neurorehabilitation nurses that could be taught by means of a specialization course...
  5. doi request reprint Epilepsy in the end-of-life phase in patients with high-grade gliomas
    Andrea Pace
    Palliative Home Care Unit for Brain Tumor Patients, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy
    J Neurooncol 111:83-6. 2013
    ..Loss of seizure control in the end-of-life phase may influence the quality of life of patients and their caregivers...
  6. pmc Brain metastases from solid tumors: disease outcome according to type of treatment and therapeutic resources of the treating center
    Alessandra Fabi
    Department of Medical Oncology, Regina Elena National Cancer Institute, Rome Italy
    J Exp Clin Cancer Res 30:10. 2011
    ..To evaluate the therapeutic strategies commonly employed in the clinic for the management of brain metastases (BMs) and to correlate disease outcome with type of treatment and therapeutic resources available at the treating center...
  7. pmc The role side effects play in the choice of antiepileptic therapy in brain tumor-related epilepsy: a comparative study on traditional antiepileptic drugs versus oxcarbazepine
    Marta Maschio
    Center for Tumor related Epilepsy, Department of Neuroscience and Cervical Facial Pathology, National Institute for Cancer Regina Elena, Via Elio Chianesi 53, 00144 Roma, Italy
    J Exp Clin Cancer Res 28:60. 2009
    ..Seizure control doesn't represent the only challenging goal in patients with brain tumor-related epilepsy. Side effects have often taken precedence for patients' quality of life...
  8. pmc Quantitative analysis of CT-perfusion parameters in the evaluation of brain gliomas and metastases
    Anna Maria Di Nallo
    Regina Elena National Cancer Institute, Rome, Italy
    J Exp Clin Cancer Res 28:38. 2009
    ..The perfusion scan provided 11 parametric maps, including Cerebral Blood Volume (CBV), Cerebral Blood Flow (CBF), Average Perfusion (Pmean) and Permeability-surface area product (PS)...
  9. pmc Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation
    Alessandra Fabi
    Division of Medical Oncology, Regina Elena Cancer Institute, Rome, Italy
    BMC Cancer 9:101. 2009
    ..Also, the impact of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation status on fotemustine activity has never been explored in the clinical setting...
  10. doi request reprint End of life issues in brain tumor patients
    Andrea Pace
    Department of Neuroscience, Palliative Home Care Unit for Brain Tumor Patients, Regina Elena National Cancer Institute, Via Chianesi 53, Rome, 00144, Italy
    J Neurooncol 91:39-43. 2009
    ..Development of home care models of assistance may represent an alternative to in-hospital care for the management of patients dying of brain tumor and may improve the quality of end-of-life care...
  11. ncbi request reprint Home rehabilitation for brain tumor patients
    A Pace
    Palliative Home Care Unit for Brain Tumor Patients, Regina Elena National Cancer Institute, Rome, Italy
    J Exp Clin Cancer Res 26:297-300. 2007
    ..Rehabilitation at home in brain tumor patients was associated with significant functional gain measured both with BI and KPS. The benefit of rehabilitation may influence patient's perception of quality of life...
  12. ncbi request reprint Chemotherapy in neoplastic meningitis
    Andrea Pace
    Regina Elena National Cancer Institute, Rome, Italy
    Crit Rev Oncol Hematol 60:194-200. 2006
    ..This review summarizes intrathecal and systemic chemotherapeutic options in the treatment of NM and the related toxicities...
  13. doi request reprint Vitamin E neuroprotection for cisplatin neuropathy: a randomized, placebo-controlled trial
    A Pace
    Department of Neuroscience, Regina Elena National Cancer Institute, 00144 Rome, Italy
    Neurology 74:762-6. 2010
    ..The present study evaluates the neuroprotective effect of antioxidant supplementation (vitamin E) in patients treated with cisplatin chemotherapy...
  14. doi request reprint Supportive care in neurooncology
    Andrea Pace
    Division of Neurology, Regina Elena Cancer Institute, Rome, Italy
    Curr Opin Oncol 22:621-6. 2010
    ..On the other hand, some important problems such as rehabilitation, depression, psychological support/communication and end-of-life issues/treatment decisions have been poorly investigated so far...
  15. ncbi request reprint Neuroprotective effect of vitamin E supplementation in patients treated with cisplatin chemotherapy
    Andrea Pace
    Neuroscience Department, Experimental Chemotherapy Laboratory, Regina Elena National Cancer Institute, Rome, Italy
    J Clin Oncol 21:927-31. 2003
    ..The aim of this study is to evaluate the neuroprotective effect of antioxidant supplementation with vitamin E in patients treated with cisplatin chemotherapy...
  16. doi request reprint Oxcarbazepine monotherapy in patients with brain tumor-related epilepsy: open-label pilot study for assessing the efficacy, tolerability and impact on quality of life
    M Maschio
    Department of Neuroscience and Cervical Facial Pathology, Center for Tumor related Epilepsy, National Institute for Cancer, Regina Elena, Via Elio Chianesi 53, 00144, Rome, Italy
    J Neurooncol 106:651-6. 2012
    ..011) and no change over time. Oxcarbazepine seems to be efficacious in controlling seizures and in improving mood in patients with BTRE, but special caution should be taken when it is administered during radiotherapy...
  17. ncbi request reprint Early post-operative MRI: correlation with progression-free survival and overall survival time in malignant gliomas
    A Vidiri
    Department of Diagnostic Imaging, Regina Elena Cancer Institute, Rome, Italy
    J Exp Clin Cancer Res 25:177-82. 2006
    ..The study confirms that early-MR has to be considered an accurate technique for monitoring the extension of malignant glioma surgical resection and shows a good correlation between early-MR findings, PFS and ST...
  18. ncbi request reprint A pilot study on the relation between cisplatin neuropathy and vitamin E
    L Bove
    Service of Neurology, Regina Elena National Cancer Institute, Rome, Italy
    J Exp Clin Cancer Res 20:277-80. 2001
    ..Given the lack of toxicity of vitamin E, we need to systematically assess the possible neuroprotective role of vitamin E supplementation in patients treated with cisplatin chemotherapy...
  19. ncbi request reprint Outcome and tolerability of topiramate in brain tumor associated epilepsy
    M Maschio
    Epilepsy Outpatient Center, Department of Neuroscience and Cervical Facial Pathology, National Institute for Cancer Regina Elena, Via Elio Chianesi 53, Roma, 00144, Italy
    J Neurooncol 86:61-70. 2008
    ..Tumor-related seizures are difficult to control with AEDs; the precise reasons for this difficulty are not yet clear. Using TPM, we obtained good seizure control with a low incidence of side effects...
  20. doi request reprint Lacosamide as add-on in brain tumor-related epilepsy: preliminary report on efficacy and tolerability
    M Maschio
    Center for Tumor related Epilepsy, Neurology Unit, Department of Neuroscience and Cervical Facial Pathology, National Institute for Cancer Regina Elena, Via Elio Chianesi 53, 00144 Rome, Italy
    J Neurol 258:2100-4. 2011
    ..However, larger samples are necessary in order to draw definitive conclusions...
  21. ncbi request reprint Demyelinating disease in monoclonal gammopathy of undetermined significance
    E Galie
    Neurology Division, Regina Elena Institute, Rome, Italy
    J Exp Clin Cancer Res 22:337-9. 2003
    ..However, in the end, there is the possibility of casual association with a poorly functioning immune system connected to age...
  22. ncbi request reprint Quality-of-life assessment in patients who had been surgically treated for cerebellar pilocytic astrocytoma in childhood
    Alfredo Pompili
    Division of Neurosurgery, Regina Elena National Cancer Institute, Rome, Italy
    J Neurosurg 96:229-34. 2002
    ..The study reported here was aimed at assessing the quality of life (QOL) of these adults, which is defined as a person's sense of well-being, as derived from his or her current experience of life as a whole...
  23. ncbi request reprint Alpha-tocopherol protects against cisplatin-induced toxicity without interfering with antitumor efficacy
    Carlo Leonetti
    Experimental Chemotherapy Laboratory, Regina Elena Cancer Institute, Rome, Italy
    Int J Cancer 104:243-50. 2003
    ....
  24. doi request reprint Metastases to the cerebellum. Results and prognostic factors in a consecutive series of 44 operated patients
    Alfredo Pompili
    Division of Neurosurgery, Regina Elena National Cancer Institute, Via Elio Chianesi 53, Rome, Italy
    J Neurooncol 88:331-7. 2008
    ..Among the prognostic factors, the cerebellar location was never considered, although this results in hydrocephalus, brain stem compression, ataxia, intracranial hypertension...
  25. ncbi request reprint Levetiracetam therapy in patients with brain tumour and epilepsy
    Marta Maschio
    Department of Neuroscience and Cervical Facial Pathology, Epilepsy Outpatient s Centre, Regina Elena National Institute for Cancer, Via Elio Chianesi 53, 00144, Rome, Italy
    J Neurooncol 80:97-100. 2006
    ..Controlled studies on larger populations are warranted to confirm these open observations...
  26. doi request reprint Temozolomide treatment does not affect topiramate and oxcarbazepine plasma concentrations in chronically treated patients with brain tumor-related epilepsy
    Marta Maschio
    Center for Tumor related Epilepsy, Department of Neuroscience and Cervical Facial Pathology, National Institute for Cancer Regina Elena, Via Elio Chianesi 53, 00144 Rome, Italy
    J Neurooncol 90:217-21. 2008
    ..We studied the effect of temozolomide therapy on the disposition of the new antiepileptic drugs topiramate (TPM) or oxcarbazepine (OXC)...
  27. pmc Activity and safety of bevacizumab plus fotemustine for recurrent malignant gliomas
    V Vaccaro
    Department of Medical Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy
    Biomed Res Int 2014:351252. 2014
    ..Bevacizumab plus FTM showed activity and good tolerability in pretreated MGs. Further investigations are needed in order to verify the benefits deriving from the addition of B to a cytotoxic in this clinical setting of patients. ..
  28. ncbi request reprint Choroid plexus carcinoma in the adult: is there a role for chemotherapy?
    A Fabi
    Division of Medical Oncology A, Regina Elena National Cancer Institute, Rome, Italy
    J Exp Clin Cancer Res 24:493-6. 2005
    ..We report a rare case of an adult woman affected by a choroid plexus tumour and a discussion on the therapeutic management of this uncommon adult malignancy...
  29. ncbi request reprint Fixed dose-rate gemcitabine as radiosensitizer for newly diagnosed glioblastoma: a dose-finding study
    Alessandra Fabi
    Division of Medical Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy
    J Neurooncol 87:79-84. 2008
    ..Thus, fixed dose-rate gemcitabine at 175 mg/m(2)/weekly is the recommended regimen for further evaluation in a phase II study that is presently in progress...
  30. ncbi request reprint Peripheral neurotoxicity of weekly paclitaxel chemotherapy: a schedule or a dose issue?
    Andrea Pace
    Department of Neurology, Regina Elena National Cancer Institute, Rome, Italy
    Clin Breast Cancer 7:550-4. 2007
    ..The aim of this study was to assess the incidence of peripheral neurotoxicity in patients affected by advanced breast cancer treated with weekly paclitaxel...
  31. ncbi request reprint Bone metastasis from glioblastoma multiforme without central nervous system relapse: a case report
    Alessandra Fabi
    Department of Medical Oncology, Regina Elena National Cancer Institute, Rome, Italy
    Anticancer Res 24:2563-5. 2004
    ..We report the case of a man affected by a glioblastoma who had a lumbar spine metastases without any brain relapse after excision of cerebral glioblastoma multiforme and brain radiotherapy...
  32. doi request reprint Depression in patients with high-grade glioma: results of the Glioma Project
    Andrea Pace
    Neurosurgery 56:E629. 2005
  33. ncbi request reprint [Intrathecal chemotherapy treatment of neoplastic meningitis from solid tumors using liposomal cytarabine: experience at the Istituto Regina Elena di Roma]
    Andrea Pace
    Servizio di Neurologia, Istituto Nazionale Tumori Regina Elena IRCCS, Roma
    Tumori 93:suppl 9-12. 2007
  34. ncbi request reprint The Total Neuropathy Score as an assessment tool for grading the course of chemotherapy-induced peripheral neurotoxicity: comparison with the National Cancer Institute-Common Toxicity Scale
    Guido Cavaletti
    Dipartimento di Neuroscienze e Tecnologie Biomediche, Universita di Milano Bicocca, Monza, Italy
    J Peripher Nerv Syst 12:210-5. 2007
    ..Moreover, both the TNS and the TNSc showed a higher sensitivity to CIPN changes. We, therefore, propose the TNSc as a reliable method for assessing not only the severity but also the changes in CIPN...
  35. ncbi request reprint Multi-center assessment of the Total Neuropathy Score for chemotherapy-induced peripheral neurotoxicity
    Guido Cavaletti
    Department of Neurosciences and Biomedical Technologies, University of Milan Bicocca, Milan, Italy
    J Peripher Nerv Syst 11:135-41. 2006
    ..The longer time needed to calculate the TNSr and TNSc in comparison to the ECOG or the NCI-CTC 2.0 scales is offset by the more detailed knowledge of the CIPN characteristics...
  36. ncbi request reprint Multiple endocrine neoplasia type 1 and Zollinger-Ellison syndrome: a prospective study of 107 cases and comparison with 1009 cases from the literature
    Fathia Gibril
    Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 1804, USA
    Medicine (Baltimore) 83:43-83. 2004
    ..In this study we have identified a number of important clinical and laboratory features of MEN1/ZES that were not previously appreciated, which should contribute to earlier diagnosis and improve both short- and long-term management...
  37. ncbi request reprint The cholecystokinin2-receptor mediates calcitonin secretion, gene expression, and proliferation in the human medullary thyroid carcinoma cell line, TT
    Michael Blaker
    Medizinische Klinik I, Zentrum fur Innere Medizin, Universitatsklinikum Hamburg Eppendorf, Martinistrabetae 52, 20246 Hamburg, Germany
    Regul Pept 118:111-7. 2004
    ..Our findings suggest physiological functions for the CCK(2)R in calcitonin-secretion and gene expression as well as a pathophysiological role in MTC proliferation. CCK(2)R antagonists might have therapeutic potential in these tumors...
  38. ncbi request reprint Salvage chemotherapy with temozolomide in primary CNS lymphomas: preliminary results of a phase II trial
    Michele Reni
    Department of Radiochemotherapy, S Raffaele Hospital Scientific Institute, Milan, Italy
    Eur J Cancer 40:1682-8. 2004
    ..Although some patients had a poor PS and had been heavily pre-treated, temozolomide yielded 26% objective responses and was well tolerated without any major toxicity...
  39. ncbi request reprint Depression in patients with high-grade glioma: results of the Glioma Project
    Andrea Pace
    Neurosurgery 56:E873. 2005
  40. ncbi request reprint Subtemporal trantentorial approach
    Alfredo Pompili
    J Neurosurg 104:854-5; author reply 855-6. 2006
  41. ncbi request reprint Mild cognitive impairment: the transition to Alzheimer's disease
    Andrea Pace
    Emergency Department, Riverside Methodist Hospital, Columbus, Ohio, USA
    JAAPA 21:40-4. 2008
  42. ncbi request reprint Weekly epirubicin and paclitaxel with granulocyte colony-stimulating factor support in previously untreated metastatic breast cancer patients: a phase II study
    Cecilia Nistico
    Department of Medical Oncology, Regina Elena National Cancer Institute, Roma, Italy
    Anticancer Drugs 18:687-92. 2007
    ....