Giorgio Arcangeli

Summary

Affiliation: Regina Elena Cancer Institute
Country: Italy

Publications

  1. doi Retrospective comparison of external beam radiotherapy and radical prostatectomy in high-risk, clinically localized prostate cancer
    Giorgio Arcangeli
    Department of Radiotherapy, Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 75:975-82. 2009
  2. ncbi Analysis of toxicity in patients with high risk prostate cancer treated with intensity-modulated pelvic radiation therapy and simultaneous integrated dose escalation to prostate area
    Stefano Arcangeli
    Department of Radiation Oncology, Regina Elena National Cancer Institute, Rome, Italy
    Radiother Oncol 84:148-55. 2007
  3. doi A prospective phase III randomized trial of hypofractionation versus conventional fractionation in patients with high-risk prostate cancer
    Giorgio Arcangeli
    Department of Radiotherapy, Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 78:11-8. 2010
  4. ncbi A phase III randomized study on the sequencing of radiotherapy and chemotherapy in the conservative management of early-stage breast cancer
    Giorgio Arcangeli
    Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 64:161-7. 2006
  5. ncbi Postoperative adjuvant chemoradiation in completely resected locally advanced gastric cancer
    Giorgio Arcangeli
    Division of Radiation Oncology, Regina Elena National Cancer Institute, Via E Chianesi 53, 00144 Rome, Italy
    Int J Radiat Oncol Biol Phys 54:1069-75. 2002
  6. ncbi Postoperative chemoradiotherapy in rectal cancer. Late results of a pilot study
    Roberto Tersigni
    Department of Surgical Sciences, General Surgery 1, San Camillo Hospital, Rome, Italy
    Hepatogastroenterology 51:1679-85. 2004
  7. pmc Accelerated hypofractionated radiotherapy as adjuvant regimen after conserving surgery for early breast cancer: interim report of toxicity after a minimum follow up of 3 years
    Paola Pinnarò
    Radiotherapy Department, Regina Elena National Cancer Institute, Rome, Italy
    J Exp Clin Cancer Res 29:9. 2010
  8. ncbi Phase I-II study of intraoperative radiation therapy (IORT) after radical prostatectomy for prostate cancer
    Biancamaria Saracino
    Department of Radiotherapy, Regina Elena Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 71:1049-56. 2008
  9. doi Updated results and patterns of failure in a randomized hypofractionation trial for high-risk prostate cancer
    Stefano Arcangeli
    Department of Radiation Oncology, Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 84:1172-8. 2012
  10. ncbi Analysis of salivary flow and dose-volume modeling of complication incidence in patients with head-and-neck cancer receiving intensity-modulated radiotherapy
    Simona Marzi
    Laboratorio di Fisica Medica e Sistemi Esperti, Istituto Regina Elena, Rome, Italy
    Int J Radiat Oncol Biol Phys 73:1252-9. 2009

Collaborators

Detail Information

Publications34

  1. doi Retrospective comparison of external beam radiotherapy and radical prostatectomy in high-risk, clinically localized prostate cancer
    Giorgio Arcangeli
    Department of Radiotherapy, Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 75:975-82. 2009
    ..a conservative approach such as external beam radiotherapy (EBRT) plus androgen deprivation therapy using an intent-to-treat analysis on two pretreatment defined, concurrently treated, high-risk patient populations...
  2. ncbi Analysis of toxicity in patients with high risk prostate cancer treated with intensity-modulated pelvic radiation therapy and simultaneous integrated dose escalation to prostate area
    Stefano Arcangeli
    Department of Radiation Oncology, Regina Elena National Cancer Institute, Rome, Italy
    Radiother Oncol 84:148-55. 2007
    ..To report the treatment-related morbidity in patients with prostate cancer treated with an optimized pelvic intensity-modulated radiation therapy (IMRT) and simultaneous integrated dose escalation to prostate/prostate bed...
  3. doi A prospective phase III randomized trial of hypofractionation versus conventional fractionation in patients with high-risk prostate cancer
    Giorgio Arcangeli
    Department of Radiotherapy, Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 78:11-8. 2010
    ..To compare the toxicity and efficacy of hypofractionated (62 Gy/20 fractions/5 weeks, 4 fractions per week) vs. conventional fractionation radiotherapy (80 Gy/40 fractions/8 weeks) in patients with high-risk prostate cancer...
  4. ncbi A phase III randomized study on the sequencing of radiotherapy and chemotherapy in the conservative management of early-stage breast cancer
    Giorgio Arcangeli
    Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 64:161-7. 2006
    ..To compare two different timings of radiation treatment in patients with breast cancer who underwent conservative surgery and were candidates to receive adjuvant cyclophosphamide, methotrexate, and fluorouracil (CMF) chemotherapy...
  5. ncbi Postoperative adjuvant chemoradiation in completely resected locally advanced gastric cancer
    Giorgio Arcangeli
    Division of Radiation Oncology, Regina Elena National Cancer Institute, Via E Chianesi 53, 00144 Rome, Italy
    Int J Radiat Oncol Biol Phys 54:1069-75. 2002
    ..We explored the feasibility of a chemoradiation regime consisting of concomitant hyperfractionated radiotherapy and 5-fluorouracil protracted venous infusion (5-FU PVI)...
  6. ncbi Postoperative chemoradiotherapy in rectal cancer. Late results of a pilot study
    Roberto Tersigni
    Department of Surgical Sciences, General Surgery 1, San Camillo Hospital, Rome, Italy
    Hepatogastroenterology 51:1679-85. 2004
    ..However, hematological and intestinal toxicity also increased. Experimental and clinical studies showed an increased radiation effect with an acceptable toxicity by delivering drug via a continuous intravenous infusion...
  7. pmc Accelerated hypofractionated radiotherapy as adjuvant regimen after conserving surgery for early breast cancer: interim report of toxicity after a minimum follow up of 3 years
    Paola Pinnarò
    Radiotherapy Department, Regina Elena National Cancer Institute, Rome, Italy
    J Exp Clin Cancer Res 29:9. 2010
    ..Accelerated hypofractionation is an attractive approach for adjuvant whole breast radiotherapy. In this study we evaluated the adverse effects at least 3 years post an accelerated hypofractionated whole breast radiotherapy schedule...
  8. ncbi Phase I-II study of intraoperative radiation therapy (IORT) after radical prostatectomy for prostate cancer
    Biancamaria Saracino
    Department of Radiotherapy, Regina Elena Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 71:1049-56. 2008
    ..5-3 Gy, which is lower than that assumed for late-responsive normal tissues. Therefore the administration of a single, intraoperative dose of irradiation should represent a convenient irradiation modality in prostate cancer...
  9. doi Updated results and patterns of failure in a randomized hypofractionation trial for high-risk prostate cancer
    Stefano Arcangeli
    Department of Radiation Oncology, Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 84:1172-8. 2012
    ..To report long-term results and patterns of failure after conventional and hypofractionated radiation therapy in high-risk prostate cancer...
  10. ncbi Analysis of salivary flow and dose-volume modeling of complication incidence in patients with head-and-neck cancer receiving intensity-modulated radiotherapy
    Simona Marzi
    Laboratorio di Fisica Medica e Sistemi Esperti, Istituto Regina Elena, Rome, Italy
    Int J Radiat Oncol Biol Phys 73:1252-9. 2009
    ..To investigate dose-volume effects of salivary flow and the functional recovery over time, using salivary function data and different models of normal tissue complication probability (NTCP)...
  11. doi A novel dose constraint to reduce xerostomia in head-and-neck cancer patients treated with intensity-modulated radiotherapy
    Lidia Strigari
    Laboratory of Medical Physics and Expert Systems, Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 77:269-76. 2010
    ....
  12. doi Acute and late toxicity in a randomized trial of conventional versus hypofractionated three-dimensional conformal radiotherapy for prostate cancer
    Giorgio Arcangeli
    Department of Radiation Oncology, Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 79:1013-21. 2011
    ..To compare the toxicity between hypofractionation vs. conventional fractionation schedules in patients with high-risk prostate cancer...
  13. doi Long-term results of a randomized trial on the sequencing of radiotherapy and chemotherapy in breast cancer
    Paola Pinnarò
    Department of Radiotherapy, Regina Elena National Cancer Institute, Rome, Italy
    Am J Clin Oncol 34:238-44. 2011
    ..A prospective, phase III randomized study was undertaken to compare the outcomes of 2 different radiotherapy and chemotherapy sequences in conservatively treated patients with breast cancer...
  14. pmc Toxicity and cosmesis outcomes after single fraction partial breast irradiation in early stage breast cancer
    Paola Pinnarò
    Department of Radiation Oncology, Laboratory of Medical Physics and Expert Systems, Regina Elena National Cancer Institute, Rome, Italy
    Radiat Oncol 6:155. 2011
    ..To report the clinical outcome after a Single Shot 3D-CRT PBI (SSPBI) in breast cancer patients after conservative surgery (ClinicalTrials.gov Identifier: NCT01316328)...
  15. pmc Modeling of alpha/beta for late rectal toxicity from a randomized phase II study: conventional versus hypofractionated scheme for localized prostate cancer
    Simona Marzi
    Laboratorio di Fisica Medica e Sistemi Esperti, Istituto Regina Elena, Rome, Italy
    J Exp Clin Cancer Res 28:117. 2009
    ..The main purpose of this study is to evaluate the response of rectum wall to changes in fractionation and to quantify the alpha/beta ratio for late rectal toxicity..
  16. ncbi Relationships between rectal wall dose-volume constraints and radiobiologic indices of toxicity for patients with prostate cancer
    Simona Marzi
    Laboratorio di Fisica Medica e Sistemi Esperti, Istituto Regina Elena, Rome, Italy
    Int J Radiat Oncol Biol Phys 68:41-9. 2007
    ..The purpose of this article was to investigate how exceeding specified rectal wall dose-volume constraints impacts on the risk of late rectal bleeding by using radiobiologic calculations...
  17. ncbi Conservative treatment of invasive bladder carcinoma by transurethral resection, protracted intravenous infusion chemotherapy, and hyperfractionated radiotherapy: long term results
    Donatella Tirindelli Danesi
    Department of Biotechnologies, Health and Ecosystems Protection, Section of Toxicology and Biomedical Sciences, ENEA Casaccia, Rome, Italy
    Cancer 101:2540-8. 2004
    ....
  18. doi Clinical and dosimetric predictors of acute toxicity after a 4-week hypofractionated external beam radiotherapy regimen for prostate cancer: results from a multicentric prospective trial
    Stefano Arcangeli
    Departments of Radiotherapy, Regina Elena National Cancer Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 73:39-45. 2009
    ..To investigate predictors for gastrointestinal (GI) and genitourinary (GU) acute toxicity after a short-course hypofractionated radiotherapy regimen for prostate cancer...
  19. doi Treatment and outcome of advanced external auditory canal and middle ear squamous cell carcinoma
    Giovanni Cristalli
    Department of Otolaryngology, Head and Neck Surgery, National Cancer Institute Regina Elena, Rome, Italy
    J Craniofac Surg 20:816-21. 2009
    ..Postoperative radiotherapy is necessary to obtain good local control; no major adverse effects were observed in the intraoperative radiotherapy patients. The incidence of major complication is minimal after pedicle flap reconstruction...
  20. doi Mathematical model for evaluating incidence of acute rectal toxicity during conventional or hypofractionated radiotherapy courses for prostate cancer
    Lidia Strigari
    Laboratory of Medical Physics and Expert Systems, Regina Elena Institute, Rome, Italy
    Int J Radiat Oncol Biol Phys 73:1454-60. 2009
    ..To describe the radiation-induced acute rectal toxicity (ART) using a modified Lyman-Kutcher-Burman normal tissue complication probability model and parameters set, taking into account the overall treatment time...
  21. pmc Dose escalation using ultra-high dose IMRT in intermediate risk prostate cancer without androgen deprivation therapy: preliminary results of toxicity and biochemical control
    Maria Grazia Petrongari
    Department of Radiation Oncology, Regina Elena National Cancer Institute, Rome, Italy
    J Exp Clin Cancer Res 32:103. 2013
    ..To investigate the feasibility of dose escalation (86 Gy at 2 Gy/fraction) with intensity modulated radiation therapy (IMRT) in intermediate-risk prostate cancer without androgen deprivation therapy...
  22. doi Intraoperative radiation therapy as an "early boost" in locally advanced head and neck cancer: preliminary results of a feasibility study
    Laura Marucci
    Department of Radiation Oncology, Regina Elena Institute, Rome, Italy
    Head Neck 30:701-8. 2008
    ..The acute toxicity of intraoperative radiation therapy (IORT) delivered as an "early boost" after tumor resection in patients with locally advanced head and neck cancer was evaluated...
  23. ncbi Color Doppler quantitative measures to predict outcome of biopsies in prostate cancer
    Lidia Strigari
    Laboratory of Medical Physics and Expert Systems, Regina Elena National Cancer Institute, Rome 00144, Italy
    Med Phys 35:4793-9. 2008
    ..The aim was to correlate the color Doppler flow activity pre- and postradiotherapy, using transrectal color Doppler ultrasonography (CDUS) and the 2 year positive biopsy rate after radiotherapy in patients with prostate cancer...
  24. ncbi Persistence of HPV after radio-chemotherapy in locally advanced cervical cancer
    Gianna Badaracco
    Division of Virology, Regina Elena Cancer Institute, Rome, Italy
    Oncol Rep 23:1093-9. 2010
    ..03) tool to assess the efficacy of the treatment...
  25. ncbi Accelerated hyperfractionated radiotherapy and concurrent protracted venous infusion chemotherapy in locally advanced head and neck cancer
    Giorgio Arcangeli
    Regina Elena National Cancer Institute, Division of Radiation Oncology, Rome, Italy
    Am J Clin Oncol 25:431-7. 2002
    ..The long-term results of this study suggest that this chemoradiation regimen has the potential of achieving a significant improvement over standard therapy while avoiding significant toxicity...
  26. doi Hypofractionated Conformal Radiotherapy (HCRT) for primary and metastatic lung cancers with small dimension : efficacy and toxicity
    Maria Alessandra Mirri
    S C Radioterapia Oncologica, Regina Elena National Cancer Institute, Rome, Italy
    Strahlenther Onkol 185:27-33. 2009
    ..To report on the clinical outcome of hypofractionated conformal radiotherapy (HCRT) for medically inoperable stage I non-small cell lung carcinoma (NSCLC) or limited pulmonary metastases </= 5 cm in diameter...
  27. ncbi Fixed dose-rate gemcitabine as radiosensitizer for newly diagnosed glioblastoma: a dose-finding study
    Alessandra Fabi
    Division of Medical Oncology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy
    J Neurooncol 87:79-84. 2008
    ..Thus, fixed dose-rate gemcitabine at 175 mg/m(2)/weekly is the recommended regimen for further evaluation in a phase II study that is presently in progress...
  28. ncbi A study of the effect of setup errors and organ motion on prostate cancer treatment with IMRT
    Valeria Landoni
    Laboratorio di Fisica Medica e Sistemi Esperti, Istit4uto Regina Elena, Rome, Italy
    Int J Radiat Oncol Biol Phys 65:587-94. 2006
    ..To assess the influence of setup errors and organ motion in terms of the probability of tumor control and normal-tissue complications by tumor control probability and normal-tissue complication probability...
  29. ncbi Setup verification and in vivo dosimetry during intraoperative radiation therapy (IORT) for prostate cancer
    Antonella Soriani
    Laboratory of Medical Physics, Istituto Regina Elena, Via Elio Chianesi 53, 00144, Roma, Italy
    Med Phys 34:3205-10. 2007
    ..Radio-opaque clips and liquid were necessary to obtain good visible images. In vivo MOSFETs dosimetry is feasible and reliable. A satisfactory agreement between measured and expected doses was found...
  30. pmc Epidemiology of prostate cancer and treatment remarks
    Stefano Arcangeli
    Stefano Arcangeli, Valentina Pinzi, Giorgio Arcangeli, Department of Radiotherapy, Regina Elena National Cancer Institute, 00144 Rome, Italy
    World J Radiol 4:241-6. 2012
    ....
  31. ncbi Comparison between the ideal reference dose level and the actual reference dose level from clinical 3D radiotherapy treatment plans
    Antonella Bufacchi
    AFaR U O C Medical Physics, S Giovanni Calibita Fatebenefratelli Hospital, Rome, Italy
    Radiother Oncol 92:68-75. 2009
    ..Retrospective study of 3D clinical treatment plans based on radiobiological considerations in the choice of the reference dose level from tumor dose-volume histograms...
  32. ncbi Postoperative chemoradiotherapy in rectal cancer. Long-term results of a pilot study
    Roberto Tersigni
    Department of Surgery General Surgery 1 Flajani, San Camillo Forlanini Hospital, Rome, Italy
    Chir Ital 55:333-44. 2003
    ..Adjuvant therapy needs to be re-assessed in trials using total mesorectal excision as the standard operative technique...
  33. pmc Endothelial NOS, estrogen receptor beta, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer
    Simona Nanni
    Department of Experimental Oncology, Regina Elena Cancer Institute, Rome, Italy
    J Clin Invest 119:1093-108. 2009
    ..Furthermore, proposing eNOS as a therapeutic target fosters innovative therapies for PCa with NO inhibitors, which are employed in preclinical trials in non-oncological diseases...
  34. ncbi Phase II study of a four-week hypofractionated external beam radiotherapy regimen for prostate cancer: report on acute toxicity
    Guy Soete
    Department of Radiotherapy, Oncology Center AZ VUB, Jette, Belgium
    Radiother Oncol 80:78-81. 2006
    ..To evaluate the early side effects of a short course hypofractionated radiotherapy regimen in prostate cancer...