Research Topics
Genomes and Genes | Sabina PucciSummaryCountry: Italy Publications
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Publications
Persistent Chlamydia pneumoniae infection of cardiomyocytes is correlated with fatal myocardial infarctionLuigi Giusto Spagnoli
Cattedra di Anatomia ed Istologia Patologica, Dipartimento di Biopatologia e Diagnostica per Immagini, Universita di Roma Tor Vergata, Via Montpellier 1, Rome, Italy
Am J Pathol 170:33-42. 2007..Our results suggest that CP may underlie both coronary and myocardial vulnerabilities in patients who died of AMI and corroborate the notion that CP may act by reducing cardiac reserves, thus worsening the ischemic burden of myocardium...
Carnitine palmitoyltransferase I in human carcinomas: a novel role in histone deacetylation?Paola Mazzarelli
Institute of Anatomic Pathology, Dept of Biopathology, University of Rome Tor Vergata, Rome, Italy
Cancer Biol Ther 6:1606-13. 2007..The peculiar localization of CPT1 in the nuclei of human carcinomas and the disclosed functional link between nuclear CPT1 and HDAC1 propose a new role of CPT1 in the histonic acetylation level of tumors...
Clusterin in stool: a new biomarker for colon cancer screening?Sabina Pucci
Department of Biopathology, University of Rome Tor Vergata, Rome, Italy
Am J Gastroenterol 104:2807-15. 2009..In this report, we investigated whether sCLU is released in the blood and stool of colon cancer patients in order to study sCLU as a potential diagnostic molecular marker for colon cancer screening...
Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progressionSabina Pucci
Department of Biopathology, University of Rome Tor Vergata, Rome, Italy
Cell Cycle 8:473-81. 2009..Uncovering the molecular mechanisms of action of these factors may offer strategies for selectively manipulate the cancer cells sensitivity to therapy...
Modulation of Ku70/80, clusterin/ApoJ isoforms and Bax expression in indocyanine-green-mediated photo-oxidative cell damageFederico Ricci
Section of Ophthalmology, University of Rome Tor Vergata, Rome, Italy
Ophthalmic Res 39:164-73. 2007..Cell viability and death induction were examined, as well as the modulation of proteins involved in cell death and DNA repair...
CLU and colon cancer. The dual face of CLU: from normal to malignant phenotypeP Mazzarelli
Department of Biopathology, Institute of Anatomic Pathology, University of Rome Tor Vergata, 00133 Rome, Italy
Adv Cancer Res 105:45-61. 2009..On the basis of results obtained by CLU immuno-dosage in blood and stool of colon cancer patients, we report that sCLU could represent a diagnostic molecular marker for colon cancer screening...
Expression analysis of the gene encoding for the U-box-type ubiquitin ligase UBE4A in human tissuesGianmarco Contino
Department of Biopathology, Institute of Anatomic Pathology, Tor Vergata University of Rome, Italy
Gene 328:69-74. 2004....
CLU "in and out": looking for a linkSabina Pucci
Department of Biopathology, Institute of Anatomic Pathology, University of Rome Tor Vergata, 00133 Rome, Italy
Adv Cancer Res 105:93-113. 2009..Further elucidation of CLU functions inside and outside ("in and out") of cancer cell are warranted for a deeper understanding of the interplay between tumor and stroma, suggesting new therapeutic cotargeting strategies...
Stool test for colorectal cancer screening: what is going on?Elena Bonanno
Anatomopathology, Department of Biopathology, University of Rome Tor Vergata, Italy
Surg Oncol 16:S43-5. 2007..A new potential stool marker of colon cancer is clusterin, a protein of particular interest for its high sensitivity and positive predictive value in patients with highly aggressive CRC...
Chapter 3: The shifting balance between CLU forms during tumor progressionSabina Pucci
Department of Biopathology, University of Rome Tor Vergata, Rome, Italy
Adv Cancer Res 104:25-32. 2009..The shifting balance between CLU forms during tumor progression, by affecting the fate of the cell, seems to be strongly influenced by the metabolic shift occurring in the different steps of tumor progression...
Modulation of different clusterin isoforms in human colon tumorigenesisSabina Pucci
Department of Biopathology, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
Oncogene 23:2298-304. 2004....
MicroRNA Dysregulation in Colon Cancer Microenvironment Interactions: The Importance of Small Things in MetastasesSabina Pucci
Department of Biopathology, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy
Cancer Microenviron 4:155-62. 2011....
