P Prandoni

Summary

Country: Italy

Publications

  1. ncbi request reprint The optimal long-term treatment of venous thromboembolism
    Paolo Prandoni
    2nd Chair of Internal Medical and Surgical Sciences, University of Padua, Italy
    Clin Adv Hematol Oncol 2:729-32. 2004
  2. ncbi request reprint Direct oral anticoagulants in the prevention of venous thromboembolism: evidence from major clinical trials
    Paolo Prandoni
    Department of Medicine, Vascular Medicine Unit, University of Padua, Padua, Italy Electronic address
    Semin Hematol 51:121-30. 2014
  3. pmc Venous and arterial thrombosis: Two aspects of the same disease?
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, Thromboembolism Unit, University Hospital of Padua Padua, Italy
    Clin Epidemiol 1:1-6. 2009
  4. doi request reprint What are the pharmacotherapy options for treating venous thromboembolism in cancer patients?
    Paolo Prandoni
    University of Padua, Department of Medicine, Clinica Medica 2, Vascular Medicine Unit, Via Giustiniani 2, 35128 Padua, Italy 39 049 8212656 39 049 8218731
    Expert Opin Pharmacother 15:799-807. 2014
  5. doi request reprint The risk of recurrent thromboembolic disorders in patients with unprovoked venous thromboembolism: new scenarios and opportunities
    Paolo Prandoni
    Department of Medicine, Thromboembolism Unit, University of Padua, Italy Electronic address
    Eur J Intern Med 25:25-30. 2014
  6. doi request reprint Aspirin and recurrent venous thromboembolism
    P Prandoni
    Department of Cardiothoracic and Vascular Sciences, Clinica Medica 2, Via Giustiniani 2, 35128 Padua, Italy
    Phlebology 28:99-104. 2013
  7. ncbi request reprint New anticoagulants for the treatment of venous thromboembolism
    P Prandoni
    Department of Cardiothoracic and Vascular Sciences, University of Padua, Padua, Italy
    Minerva Med 104:131-39. 2013
  8. doi request reprint Anticoagulant treatment of pulmonary embolism: impact and implications of the EINSTEIN PE study
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, University of Padua, Padua, Italy
    Eur J Haematol 89:281-7. 2012
  9. doi request reprint Venous thromboembolism and arterial complications
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, Clinica Medica II and Thromboembolism Unit, University Hospital of Padua, Via Giustiniani 2, Padua, Italy
    Semin Respir Crit Care Med 33:205-10. 2012
  10. doi request reprint Healthcare burden associated with the post-thrombotic syndrome and potential impact of the new oral anticoagulants
    Paolo Prandoni
    Thromboembolism Unit, Department of Cardiothoracic and Vascular Sciences, University of Padua, Padua, Italy
    Eur J Haematol 88:185-94. 2012

Detail Information

Publications117 found, 100 shown here

  1. ncbi request reprint The optimal long-term treatment of venous thromboembolism
    Paolo Prandoni
    2nd Chair of Internal Medical and Surgical Sciences, University of Padua, Italy
    Clin Adv Hematol Oncol 2:729-32. 2004
  2. ncbi request reprint Direct oral anticoagulants in the prevention of venous thromboembolism: evidence from major clinical trials
    Paolo Prandoni
    Department of Medicine, Vascular Medicine Unit, University of Padua, Padua, Italy Electronic address
    Semin Hematol 51:121-30. 2014
    ....
  3. pmc Venous and arterial thrombosis: Two aspects of the same disease?
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, Thromboembolism Unit, University Hospital of Padua Padua, Italy
    Clin Epidemiol 1:1-6. 2009
    ..Future studies are needed to clarify the nature of this association, to assess its extent, and to evaluate its implications for clinical practice...
  4. doi request reprint What are the pharmacotherapy options for treating venous thromboembolism in cancer patients?
    Paolo Prandoni
    University of Padua, Department of Medicine, Clinica Medica 2, Vascular Medicine Unit, Via Giustiniani 2, 35128 Padua, Italy 39 049 8212656 39 049 8218731
    Expert Opin Pharmacother 15:799-807. 2014
    ..Venous thromboembolism (VTE) is a frequent complication in patients with malignancies. The treatment of VTE disorders in cancer patients remains a difficult clinical task...
  5. doi request reprint The risk of recurrent thromboembolic disorders in patients with unprovoked venous thromboembolism: new scenarios and opportunities
    Paolo Prandoni
    Department of Medicine, Thromboembolism Unit, University of Padua, Italy Electronic address
    Eur J Intern Med 25:25-30. 2014
    ....
  6. doi request reprint Aspirin and recurrent venous thromboembolism
    P Prandoni
    Department of Cardiothoracic and Vascular Sciences, Clinica Medica 2, Via Giustiniani 2, 35128 Padua, Italy
    Phlebology 28:99-104. 2013
    ..Conversely, aspirin in low doses offers an appealing, safe and highly cost-effective option for the long-term prevention of recurrent events in patients with unprovoked VTE who are free from symptomatic atherosclerotic lesions...
  7. ncbi request reprint New anticoagulants for the treatment of venous thromboembolism
    P Prandoni
    Department of Cardiothoracic and Vascular Sciences, University of Padua, Padua, Italy
    Minerva Med 104:131-39. 2013
    ..Both of them have limitations for the treatment of patients with severe renal failure, and require further investigations in cancer patients and in pregnant patients with VTE. Both of them lack an antidote...
  8. doi request reprint Anticoagulant treatment of pulmonary embolism: impact and implications of the EINSTEIN PE study
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, University of Padua, Padua, Italy
    Eur J Haematol 89:281-7. 2012
    ....
  9. doi request reprint Venous thromboembolism and arterial complications
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, Clinica Medica II and Thromboembolism Unit, University Hospital of Padua, Via Giustiniani 2, Padua, Italy
    Semin Respir Crit Care Med 33:205-10. 2012
    ..Future studies are needed to clarify the nature of this association, to assess its extent, and to evaluate its implications for clinical practice...
  10. doi request reprint Healthcare burden associated with the post-thrombotic syndrome and potential impact of the new oral anticoagulants
    Paolo Prandoni
    Thromboembolism Unit, Department of Cardiothoracic and Vascular Sciences, University of Padua, Padua, Italy
    Eur J Haematol 88:185-94. 2012
    ..These agents do not have the drawbacks of the vitamin K antagonists and hold promise for more effective treatment of DVT, possibly resulting in a reduction in the incidence of post-thrombotic syndrome...
  11. doi request reprint Thigh-length versus below-knee compression elastic stockings for prevention of the postthrombotic syndrome in patients with proximal-venous thrombosis: a randomized trial
    Paolo Prandoni
    Department of Cardiovascular and Thoracic Sciences, Clinica Medica 2, University of Padua, Via Giustiniani 2, Padua, Italy
    Blood 119:1561-5. 2012
    ..017), and led to premature discontinuation of their use in 29 (21.5%) and 18 (13.6%) patients, respectively. We conclude that thigh-length CES do not offer a better protection against PTS than below-knee CES and are less well tolerated...
  12. ncbi request reprint Acquired risk factors of venous thromboembolism in medical patients
    Paolo Prandoni
    Department of Medical and Surgical Sciences 2nd Chair of Internal Medicine University of Padua, Italy
    Pathophysiol Haemost Thromb 35:128-32. 2006
    ..Recognition of the incidence and clinical importance of thrombosis will most likely encourage more widespread use of antithrombotic prophylaxis in medical patients...
  13. ncbi request reprint Cancer and venous thromboembolism. Clinical implications of strong association
    Paolo Prandoni
    Department of Medical and Surgical Sciences 2nd Chair of Internal Medicine University of Padua, Italy
    Pathophysiol Haemost Thromb 35:111-5. 2006
    ..However, whether screening for occult malignancies ultimately improves prognosis and prolongs survival remains to be demonstrated...
  14. ncbi request reprint Low-molecular-weight heparins for the long-term treatment of cancer patients with venous thromboembolism
    Paolo Prandoni
    Department of Medical and Surgical Sciences, University of Padua, Italy
    J Support Oncol 4:127-8. 2006
  15. ncbi request reprint Venous thromboembolism risk and management in women with cancer and thrombophilia
    Paolo Prandoni
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, Padua, Italy
    Gend Med 2:S28-34. 2005
    ..Venous thromboembolism (VTE) and its complications result in a high rate of morbidity and mortality...
  16. ncbi request reprint Thrombosis as a harbinger of cancer
    Paolo Prandoni
    Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
    Curr Opin Hematol 13:362-5. 2006
    ..The aim of this review is to explore the state of the art knowledge on the possible association between venous thromboembolism, especially idiopathic venous thromboembolism, and occult cancer, and to speculate on its implications...
  17. ncbi request reprint How I treat venous thromboembolism in patients with cancer
    Paolo Prandoni
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University of Padua, Via Ospedale Civile 105, 35128 Padua, Italy
    Blood 106:4027-33. 2005
    ..The evidence of lowered cancer mortality in patients on LMWH has stimulated renewed interest in these agents as antineoplastic drugs and raises the distinct possibility that cancer and thrombosis share common mechanisms...
  18. ncbi request reprint The incidence of heparin-induced thrombocytopenia in medical patients treated with low-molecular-weight heparin: a prospective cohort study
    Paolo Prandoni
    Scienze Mediche e Chirurgiche, Clinica Medica II, Universita di Padova, Italy
    Blood 106:3049-54. 2005
    ..The previous administration of heparin increases the rate of HIT...
  19. ncbi request reprint High vs. low doses of low-molecular-weight heparin for the treatment of superficial vein thrombosis of the legs: a double-blind, randomized trial
    P Prandoni
    Department of Medical and Surgical Sciences, University of Padova, Italy
    J Thromb Haemost 3:1152-7. 2005
    ....
  20. ncbi request reprint Cancer and venous thromboembolism
    Paolo Prandoni
    Department of Medical and Surgical Sciences, Second Chair of Internal Medicine, University of Padua, Padua, Italy
    Lancet Oncol 6:401-10. 2005
    ..However, the issue of whether screening for occult malignant disease ultimately improves prognosis and survival remains to be resolved...
  21. ncbi request reprint Emerging strategies for treatment of venous thromboembolism
    Paolo Prandoni
    University of Padua, Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, Via Ospedale Civile 105, 35128, Padua, Italy
    Expert Opin Emerg Drugs 10:87-94. 2005
    ..They include anti-Xa inhibitors, such as pentasaccharide, and antithrombin inhibitors, such as ximelagatran...
  22. ncbi request reprint Should cancer patients receive thromboprophylaxis to prevent catheter-related upper limb deep vein thrombosis?
    Paolo Prandoni
    Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
    Intern Emerg Med 3:85-6. 2008
  23. ncbi request reprint Risk factors of recurrent venous thromboembolism: the role of residual vein thrombosis
    Paolo Prandoni
    Department of Medical and Surgical Sciences, Second Chair of Internal Medicine University Hospital of Padua, Italy
    Pathophysiol Haemost Thromb 33:351-3. 2003
    ..4 (95% CI, 1.3 to 4.4; p =0.004) for persistent residual thrombosis versus early vein recanalization. In conclusion, residual venous thrombosis should be regarded as an important risk factor of recurrent thromboembolism...
  24. ncbi request reprint Controversial issues in the diagnosis of venous thromboembolism
    Paolo Prandoni
    Department of Medical and Surgical Sciences, Second Chair of Internal Medicine, University Hospital of Padua, Italy
    Pathophysiol Haemost Thromb 33:311-3. 2003
    ....
  25. ncbi request reprint Below-knee elastic compression stockings to prevent the post-thrombotic syndrome: a randomized, controlled trial
    Paolo Prandoni
    Department of Medical and Surgical Sciences, University Hospital of Padua, Padua, Italy
    Ann Intern Med 141:249-56. 2004
    ..Because only limited evidence suggests that elastic stockings prevent the post-thrombotic syndrome in patients with symptomatic deep venous thrombosis (DVT), these stockings are not widely used...
  26. ncbi request reprint Venous thromboembolism and the risk of subsequent symptomatic atherosclerosis
    P Prandoni
    Department of Medical and Surgical Sciences, University Hospital of Padua, Padua, Italy
    J Thromb Haemost 4:1891-6. 2006
    ..We hypothesized that patients with VTE of unknown origin would be at a higher risk of developing symptomatic atherosclerosis than patients with VTE induced by known risk factors...
  27. ncbi request reprint New strategies for the treatment of acute venous thromboembolism
    Paolo Prandoni
    Department of Medical and Surgical Sciences, University of Padua, Italy
    Semin Thromb Hemost 32:787-92. 2006
    ..Finally, new categories of drugs are emerging that have the potential to replace conventional anticoagulants in the near future. They include compounds that inhibit factor Xa or thrombin...
  28. ncbi request reprint The optimal duration of anticoagulation in patients with venous thromboembolism: how long is long enough?
    P Prandoni
    Department of Cardiothoracic and Vascular Sciences, Clinica Medica II and Thromboembolism Unit, University of Padua, Padua, Italy
    Panminerva Med 54:39-44. 2012
    ....
  29. doi request reprint The risk of subsequent cancer and arterial cardiovascular events in patients with superficial vein thrombosis in the legs
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, Clinica Medica 2, University of Padua, Padua, Italy
    Blood 118:4719-22. 2011
    ..Whether this conclusion also applies to patients whose thrombosis involves the sapheno-femoral junction remains to be demonstrated...
  30. pmc Optimal duration of anticoagulation in patients with venous thromboembolism
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, Clinica Medica II and Thromboembolism Unit, University of Padua, Italy
    Indian J Med Res 134:15-21. 2011
    ....
  31. doi request reprint Insights from the dabigatran versus warfarin trial in patients with venous thromboembolism (the RE-COVER trial)
    Paolo Prandoni
    University of Padua, Department of Cardiothoracic and Vascular Sciences, Thromboembolism Unit, Via Giustiniani 2, 35128 Padua, Italy
    Expert Opin Pharmacother 11:1035-7. 2010
    ..Study design and key results are re-evaluated in the context of previous work and future perspectives...
  32. doi request reprint Prevalence of heart diseases in patients with pulmonary embolism with and without peripheral venous thrombosis: findings from a cross-sectional survey
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, University of Padua, Italy
    Eur J Intern Med 20:470-3. 2009
    ..In up to 80% of patients with pulmonary embolism (PE) no peripheral symptomatic thrombosis can be identified. Whether the heart may represent a source of PE is unknown...
  33. ncbi request reprint Residual thrombosis on ultrasonography to guide the duration of anticoagulation in patients with deep venous thrombosis: a randomized trial
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, Clinica Medica II, Thromboembolism Unit, University of Padua, Padua, Italy
    Ann Intern Med 150:577-85. 2009
    ..The optimal duration of oral anticoagulant therapy in patients with deep venous thrombosis (DVT) of the lower extremities remains uncertain...
  34. pmc Prevention and treatment of venous thromboembolism with low-molecular-weight heparins: Clinical implications of the recent European guidelines
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, Thromboembolism Unit, University of Padua, Italy
    Thromb J 6:13. 2008
    ..This review highlights current inadequacies in the provision of thromboprophylaxis, and considers the clinical implications of the European guidelines on the prevention and treatment of VTE...
  35. ncbi request reprint Idraparinux: review of its clinical efficacy and safety for prevention and treatment of thromboembolic disorders
    Paolo Prandoni
    Department of Medical and Surgical Sciences, Thromboembolism Unit, University of Padua, 35128 Padua, Italy
    Expert Opin Investig Drugs 17:773-7. 2008
    ..Idraparinux is a synthetic pentasaccharide that binds to antithrombin with high affinity. In view of its long half-life, it is suitable for once-a-week administration...
  36. doi request reprint Risk stratification and venous thromboprophylaxis in hospitalized medical and cancer patients
    Paolo Prandoni
    Department of Medical and Surgical Sciences, Thromboembolism Unit, University of Padua, Padua, Italy
    Br J Haematol 141:587-97. 2008
    ..Recognition of the incidence and clinical importance of thrombosis will probably encourage more widespread use of antithrombotic prophylaxis in medical patients and especially in some particular types of malignancies...
  37. ncbi request reprint Cancer, thrombosis and heparin-induced thrombocytopenia
    Paolo Prandoni
    Department of Medical and Surgical Sciences, Thromboembolism Unit, University of Padua, Italy
    Thromb Res 120:S137-40. 2007
    ....
  38. ncbi request reprint Links between arterial and venous disease
    P Prandoni
    Department of Medical and Surgical Sciences, Thromboembolism Unit, University Hospital of Padua, Padua, Italy
    J Intern Med 262:341-50. 2007
    ..Future studies are needed to clarify the nature of this association, to assess its extent and to evaluate its implications for clinical practice...
  39. ncbi request reprint Venous thromboembolism and atherosclerosis: is there a link?
    P Prandoni
    Department of Medical and Surgical Sciences, Thromboembolism Unit, University Hospital of Padua, Padua, Italy
    J Thromb Haemost 5:270-5. 2007
    ..In conclusion, the separate nature of arterial and venous disorders has been challenged. Future studies are needed to clarify the nature of this association, to assess its extent, and to evaluate its implications for clinical practice...
  40. ncbi request reprint The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. A prospective cohort study in 1,626 patients
    Paolo Prandoni
    Department of Medical and Surgical Sciences, University of Padua, Via Ospedale Civile 105, 35128, Padua, Italy
    Haematologica 92:199-205. 2007
    ..The aim of this investigation was to assess the rate of recurrent VTE after withdrawal of vitamin K antagonists, and to identify clinical parameters associated with a higher likelihood of recurrence...
  41. pmc The long term clinical course of acute deep vein thrombosis of the arm: prospective cohort study
    Paolo Prandoni
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University Hospital of Padua, Via Ospedale Civile 105, 35128 Padua, Italy
    BMJ 329:484-5. 2004
  42. doi request reprint The treatment of venous thromboembolism in patients with cancer
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, Thromboembolism Unit, University of Padua, Via Giustiniani 2, 35128, Padua, Italy
    Intern Emerg Med 5:S27-30. 2010
    ..Prolongation of anticoagulation should be considered for as long as the malignant disorder is active...
  43. ncbi request reprint Recurrent thromboembolism in cancer patients: incidence and risk factors
    Paolo Prandoni
    Department of Medical and Surgical Sciences, University of Padua, Via Ospedale Civile, 105, Padua, I 35128, Italy
    Semin Thromb Hemost 29:3-8. 2003
    ..In view of the persisting high risk for recurrent thrombotic events in cancer patients, and the acceptable risk of bleeding, prolonged warfarin treatment should be considered in such patients for as long as the cancer is active...
  44. ncbi request reprint The incidence of venous thromboembolism in carriers of antithrombin, protein C or protein S deficiency associated with the HR2 haplotype of factor V: a family cohort study
    D Tormene
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University of Padua Medical School, Padua, Italy
    J Thromb Haemost 3:1414-20. 2005
    ..0%) and none in 147 non-carriers. In family members of patients with AT, PC or PS defects the coinheritance of HR2 haplotype does not seem to increase the thromboembolic risk...
  45. ncbi request reprint Upper extremity deep vein thrombosis: risk factors, diagnosis, and management
    E Bernardi
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University of Padua Medical School, Padua, Italy
    Semin Vasc Med 1:105-10. 2001
    ..Prophylaxis with low-dose heparin or low-dose warfarin is necessary whenever central venous catheters are positioned...
  46. doi request reprint The value of 64-detector row computed tomography for the exclusion of pulmonary embolism
    R Pesavento
    Department of Cardiothoracic and Vascular Sciences, 2nd chair of Internal Medicine and Thromboembolism Unit, University of Padua, Padua, Italy
    Thromb Haemost 105:901-7. 2011
    ..0 to 1.51%) and none developed PE (0 %; 95%CI, 0 to 1.0%). We conclude that 64-DCT scanning has the potential to safely exclude the presence of PE virtually in all patients presenting with clinical suspicion of this clinical disorder...
  47. ncbi request reprint Factor V Leiden mutation and the risk of venous thromboembolism in pregnant women
    D Tormene
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University of Padua Medical School, Via Ospedale Civile 105, 35128 Padua, Italy
    Haematologica 86:1305-9. 2001
    ....
  48. ncbi request reprint Prevention of venous thromboembolism in high-risk surgical and medical patients
    P Prandoni
    Department of Medical and Surgical Sciences, University of Padua Medical School, Padua, Italy
    Semin Vasc Med 1:61-70. 2001
    ..In a recent controlled randomized trial, enoxaparin in high prophylactic doses was an effective and safe measure of thromboprophylaxis in ordinary bedridden patients...
  49. doi request reprint A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score
    S Barbar
    Department of Cardiothoracic and Vascular Sciences, Second Division of Internal Medicine, University of Padua, Padova, Italy
    J Thromb Haemost 8:2450-7. 2010
    ..Prophylaxis of venous thromboembolism (VTE) in hospitalized medical patients is largely underused. We sought to assess the value of a simple risk assessment model (RAM) for the identification of patients at risk of VTE...
  50. ncbi request reprint Treatment of intermittent claudication with physical training, smoking cessation, pentoxifylline, or nafronyl: a meta-analysis
    B Girolami
    Institute of Medical Semeiotics, University Hospital of Padua, Italy
    Arch Intern Med 159:337-45. 1999
    ..There is no consensus on the efficacy of physical training, smoking cessation, and pharmacological therapy (pentoxifylline or nafronyl oxalate) in the treatment of patients with intermittent claudication at Fontaine stage II of disease...
  51. ncbi request reprint Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis
    Paolo Prandoni
    Department of Medical and Surgical Sciences, Second Chair of Internal Medicine, University Hospital of Padua, Italy
    Blood 100:3484-8. 2002
    ..These risks correlate with the extent of cancer. Possibilities for improvement using the current paradigms of anticoagulation seem limited and new treatment strategies should be developed...
  52. ncbi request reprint The incidence of heparin-induced thrombocytopenia in hospitalized medical patients treated with subcutaneous unfractionated heparin: a prospective cohort study
    Bruno Girolami
    Division of Internal Medicine, Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University Hospital of Padua, Italy
    Blood 101:2955-9. 2003
    ..Although the frequency of HIT in hospitalized medical patients treated with subcutaneous heparin is lower than that observed in other clinical settings, this complication is associated with a similarly high rate of thromboembolic events...
  53. ncbi request reprint [Therapeutic indications for acute venous thromboembolism. Current status and future perspectives]
    P Prandoni
    Clinica Medica II, Universita degli Studi di Padova, Padova, Italy
    Minerva Cardioangiol 51:361-71. 2003
    ..The efficacy and safety of emerging drugs (pentasaccharide, ximelagatran) in the treatment and secondary prevention of venous thromboembolic disorders is currently under investigation...
  54. ncbi request reprint Upper extremity deep vein thrombosis
    P Prandoni
    Department of Medical and Surgical Sciences, University of Padua Medical School, Italy
    Curr Opin Pulm Med 5:222-6. 1999
    ..This review suggests that upper extremity deep-vein thrombosis is at least as serious a disease entity as deep-vein thrombosis of the lower extremities...
  55. ncbi request reprint Postthrombotic syndrome: incidence, prevention, and management
    E Bernardi
    Department of Medical and Surgical Sciences, University of Padua Medical School, Padua, Italy
    Semin Vasc Med 1:71-80. 2001
    ..Clinical presentation has a prognostic value, as patients with initially severe symptoms enjoy a more favorable outcome than those who progressively deteriorate over time...
  56. ncbi request reprint The risk of recurrent venous thromboembolism among heterozygous carriers of factor V Leiden or prothrombin G20210A mutation. A systematic review of prospective studies
    Antonio Marchiori
    Department of Emergency Medicine, St Anthony Hospital, University of Padua, Padua, Italy
    Haematologica 92:1107-14. 2007
    ..The risk is lower with PTM and is difficult to interpret since it varies according to the assessment method used...
  57. ncbi request reprint Extensive screening for occult malignant disease in idiopathic venous thromboembolism: a prospective randomized clinical trial
    A Piccioli
    Department of Medical and Surgical Sciences, Second Division of Internal Medicine, University of Padua, Italy
    J Thromb Haemost 2:884-9. 2004
    ..9%) of the 102 control patients [absolute difference, 1.9% (95% CI, -5.5-10.9)]. Although early detection of occult cancers may be associated with improved treatment possibilities, it is uncertain whether this improves the prognosis...
  58. ncbi request reprint Heparins and venous thromboembolism: current practice and future directions
    P Prandoni
    Clinica Medica II, University of Padua, Italy
    Thromb Haemost 86:488-98. 2001
    ..The efficacy and safety of pentasaccharide (the smallest antithrombin binding sequence of heparin) in the treatment and prevention of venous thromboembolic disorders is currently under investigation...
  59. ncbi request reprint Venous thromboembolism as first manifestation of cancer
    A Piccioli
    Clinica Medica II, University Hospital of Padua, Via Ospedale Civile 105, I-35128 Padua, Italy
    Acta Haematol 106:13-7. 2001
    ..Proper clinical trials are being conducted to find an answer to these questions...
  60. ncbi request reprint The value of ultrasound screening for proximal vein thrombosis after total hip arthroplasty--a prospective cohort study
    F Verlato
    Unit Care of Angiology, University Hospital of Padua, Italy
    Thromb Haemost 86:534-7. 2001
    ..A larger controlled study in which the value of this strategy is tested against the prolongation of oral anticoagulation in patients with a negative ultrasound screening at discharge is indicated...
  61. ncbi request reprint The optimal treatment of venous thrombosis: current status and future perspectives
    P Prandoni
    Clinica Medica II, University of Padua, Italy
    Clin Lab 47:151-4. 2001
    ..These objectives are satisfactorily achieved with anticoagulant drugs (heparin and vitamin K antagonists), which therefore are the mainstays of DVT treatment. Other therapeutic options have a more limited application...
  62. ncbi request reprint Diagnosis of recurrent deep vein thrombosis
    P Prandoni
    Department of Medical and Surgical Sciences, University of Padua Medical School, Padua, Italy
    Semin Vasc Med 1:55-60. 2001
    ..The safety of withholding anticoagulants from patients with a normal quantitative CUS work-up has been recently demonstrated in a prospective management study...
  63. ncbi request reprint Cancer and venous thromboembolism
    Andrea Piccioli
    Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
    Semin Thromb Hemost 32:694-9. 2006
    ..Anticoagulant drugs appear to be an attractive strategy in cancer treatment because there is growing evidence for their possible benefits in terms of cancer prognosis and patient survival...
  64. ncbi request reprint The treatment of venous thromboembolic disorders: new challenges and opportunities
    Paolo Prandoni
    Dipartimento di Scienze Mediche e Chirurgiche, Clinica Medica II, Universita di Padova, Padua, Italy
    Haematologica 88:610-3. 2003
  65. ncbi request reprint Low-molecular-weight heparin versus compression stockings for thromboprophylaxis after knee arthroscopy: a randomized trial
    Giuseppe Camporese
    Unit of Angiology, University Hospital of Padua, Padua, Italy
    Ann Intern Med 149:73-82. 2008
    ..Knee arthroscopy, the most common orthopedic operation worldwide, carries a definite risk for deep venous thrombosis; however, postsurgical thromboprophylaxis is not routinely recommended...
  66. ncbi request reprint Circulating microparticles in carriers of factor V Leiden with and without a history of venous thrombosis
    Elena Campello
    Department of Cardiologic, Thoracic, and Vascular Sciences, 2nd Chair of Internal Medicine, University of Padua Medical School, Padua, Italy
    Thromb Haemost 108:633-9. 2012
    ..005). Our study results suggest that circulating MP may contribute to the development of thrombosis in carriers of FVL mutation...
  67. ncbi request reprint Antithrombotic drugs in the primary medical management of intermittent claudication: a meta-analysis
    B Girolami
    Institute of Medical Semeiotics, University Hospital of Padua, Italy
    Thromb Haemost 81:715-22. 1999
    ..There is no consensus on the efficacy of the antithrombotic drugs available for patients with intermittent claudication...
  68. ncbi request reprint Cancer and venous thromboembolism: an overview
    P Prandoni
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, Via Ospedale Civile 105, 35128 Padua, Italy
    Haematologica 84:437-45. 1999
    ..The aim of this study was to review briefly the mechanisms by which cancer may induce the development of thrombosis and to analyze critically the most recent clinical advances in this field...
  69. ncbi request reprint Idiopathic venous thromboembolism as a first manifestation of cancer
    A Piccioli
    Department of Medical and Surgical Sciences, University of Padua, Italy
    Haemostasis 31:37-9. 2001
    ....
  70. ncbi request reprint Risk for subsequent venous thromboembolic complications in carriers of the prothrombin or the factor V gene mutation with a first episode of deep-vein thrombosis
    P Simioni
    Department of Medical and Surgical Sciences, Second Chair of Internal Medicine, University Hospital of Padua, Italy
    Blood 96:3329-33. 2000
    ..2 to 30.1) in patients without the mutations. Prothrombin and factor V gene mutations occur frequently in patients with venous thrombosis and are associated with an increased risk for recurrent venous thromboembolic complications...
  71. ncbi request reprint Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism
    Vittorio Pengo
    Department of Clinical and Experimental Medicine, Division of Clinical Cardiology, University Hospital of Padua, Padua, Italy
    N Engl J Med 350:2257-64. 2004
    ..Chronic thromboembolic pulmonary hypertension (CTPH) is associated with considerable morbidity and mortality. Its incidence after pulmonary embolism and associated risk factors are not well documented...
  72. ncbi request reprint Superficial vein thrombosis: risk factors, diagnosis, and treatment
    Antonio Marchiori
    Department of Emergency Medicine, S Anthony Hospital, Padua, Italy
    Semin Thromb Hemost 32:737-43. 2006
    ....
  73. ncbi request reprint Prevention of thromboembolic complications in patients with atrial fibrillation
    L Spiezia
    Department of Cardiac, Thoracic and Vascular Sciences, 2nd Chair of Internal Medicine, University of Padua, Padua, Italy
    Minerva Cardioangiol 56:643-52. 2008
    ....
  74. ncbi request reprint Prolonged thromboprophylaxis with oral anticoagulants after total hip arthroplasty: a prospective controlled randomized study
    Paolo Prandoni
    Department of Medical and Surgical Sciences, Second Chair of Internal Medicine, University Hospital of Padua, Via Ospedale Civile 105, 35128 Padua, Italy
    Arch Intern Med 162:1966-71. 2002
    ..Although oral anticoagulants are still widely used for the prevention of venous thromboembolism after hip replacement, to our knowledge no study has assessed the benefit of prolonging anticoagulation beyond the hospital stay...
  75. ncbi request reprint Incidence of venous thromboembolism in asymptomatic family members who are carriers of factor V Leiden: a prospective cohort study
    Paolo Simioni
    Department of Medical and Surgical Sciences, Second Chair of Internal Medicine, University of Padua Medical School, Via Ospedale, 105 35128 Padua, Italy
    Blood 99:1938-42. 2002
    ..Screening families of symptomatic probands with the factor V Leiden mutation has the potential to identify those asymptomatic carriers who might benefit from thromboprophylaxis during risk periods...
  76. ncbi request reprint Management of thrombosis in patients with hematologic malignancies
    Andrea Piccioli
    University of Padova, Via Ospedale Civile 105, Padova 35128, Italy
    Curr Hematol Rep 1:79-83. 2002
    ..Further work is needed to provide physicians with specific guidelines for a systematic management of thrombosis in patients with hematologic malignancies...
  77. ncbi request reprint The diagnostic value of compression ultrasonography in patients with suspected recurrent deep vein thrombosis
    Paolo Prandoni
    Department of Medical and Surgical Sciences, University of Padua Medical School, Italy
    Thromb Haemost 88:402-6. 2002
    ..In conclusion, it is safe to withhold anticoagulant treatment from patients with suspected recurrent ipsilateral DVT in whom compression ultrasonography showed improved or stable vein diameters...
  78. ncbi request reprint Cancer and thromboembolic disease: how important is the risk of thrombosis?
    Paolo Prandoni
    Clinica Medica II, University of Padua, Italy
    Cancer Treat Rev 28:133-6. 2002
    ..Extensive screening for cancer in patients with idiopathic venous thrombosis allows early detection of malignancies and identification of malignancy at an early stage...
  79. ncbi request reprint Residual venous thrombosis as a predictive factor of recurrent venous thromboembolism
    Paolo Prandoni
    Department of Medical and Surgical Sciences, University of Padua, Via Ospedale Civile 105, 35128 Padua, Italy
    Ann Intern Med 137:955-60. 2002
    ..Contributing to the controversy is uncertainty about whether residual venous thrombosis, as assessed by repeated ultrasonography over time, increases the risk for recurrent thromboembolism...
  80. ncbi request reprint Anticoagulants and cancer survival
    Andrea Piccioli
    Department of Medical and Surgical Sciences, Department of Internal Medicine, University of Padova, Italy
    Semin Thromb Hemost 32:810-3. 2006
    ..Additional clinical trials are needed to provide an important step forward in this challenging setting...
  81. ncbi request reprint Postthrombotic syndrome
    Raffaele Pesavento
    Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
    Semin Thromb Hemost 32:744-51. 2006
    ..Clinical presentation helps predict the prognosis; the outcome of patients who refer with initially severe manifestations is more favorable than that of patients whose symptoms deteriorate progressively over time...
  82. ncbi request reprint Subcutaneous adjusted-dose unfractionated heparin vs fixed-dose low-molecular-weight heparin in the initial treatment of venous thromboembolism
    Paolo Prandoni
    Department of Medical and Surgical Sciences, University of Padua, Via Ospedale Civile 105, 35128 Padua, Italy
    Arch Intern Med 164:1077-83. 2004
    ..Few reports have addressed the value of unfractionated heparin (UFH) or low-molecular-weight heparin in treating the full spectrum of patients with venous thromboembolism (VTE), including recurrent VTE and pulmonary embolism...
  83. ncbi request reprint An association between atherosclerosis and venous thrombosis
    Paolo Prandoni
    Department of Medical and Surgical Sciences, Second Chair of Internal Medicine, University of Padua Medical School, Padua, Italy
    N Engl J Med 348:1435-41. 2003
    ..Whether atherosclerosis is associated with an increased risk of venous thrombosis is unknown...
  84. ncbi request reprint Low molecular weight heparins: are they interchangeable? Yes
    P Prandoni
    Department of Medical and Surgical Sciences, University of Padua Medical School, Padua, Italy
    J Thromb Haemost 1:10-1. 2003
  85. pmc Compression ultrasonography for diagnostic management of patients with clinically suspected deep vein thrombosis: prospective cohort study
    A Cogo
    Istituto di Semeiotica Medica, University of Padua, Italy
    BMJ 316:17-20. 1998
    ..8. CONCLUSION: It is safe to withhold anticoagulant treatment from patients with clinically suspected deep vein thrombosis who have a normal result on compression ultrasonography at the time of presentation and at 1 week...
  86. doi request reprint Heart disease in patients with pulmonary embolism
    Raffaele Pesavento
    Department of Cardiothoracic and Vascular Sciences, 2nd Chair of Internal Medicine, Thromboembolism Unit, University of Padua, Padua, Italy
    Curr Opin Pulm Med 16:415-8. 2010
    ..Several heart diseases are promoters of left-side cardiac thrombosis and could lead to arterial embolism. The same mechanism may be responsible for right-side cardiac thrombosis and therefore be a direct source of pulmonary embolism...
  87. ncbi request reprint Anti-prothrombin antibodies as a potential risk factor of recurrent venous thromboembolism
    Ezio Zanon
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University of Padua Medical School, Padua, Italy
    Thromb Haemost 91:255-8. 2004
    ..3; 95% CI, 1.3 to 8.6). Since aPT antibodies are more commonly identifiable in patients with multiple thrombotic episodes, they are a likely risk factor for recurrent thromboembolism...
  88. ncbi request reprint The incidence of venous thromboembolism in thrombophilic children: a prospective cohort study
    Daniela Tormene
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University of Padua Medical School, Padua, Italy
    Blood 100:2403-5. 2002
    ..Accordingly, screening for thrombophilia in otherwise healthy children younger than 15 years who belong to families with inherited defects predisposing to thrombosis seems unjustified...
  89. doi request reprint Post-thrombotic syndrome: prevalence, prognostication and need for progress
    Paolo Prandoni
    Department of Cardiothoracic and Vascular Sciences, Thromboembolism Unit, University of Padua, Padua, Italy
    Br J Haematol 145:286-95. 2009
    ..Nevertheless, due to limitations in current therapies, the management of PTS is demanding and often frustrating. Further research is required to optimize the prevention and management of this common and burdensome complication of DVT...
  90. ncbi request reprint Subcutaneous unfractionated heparin compared with low-molecular-weight heparin for the initial treatment of venous thromboembolism
    Enrico Bernardi
    Emergency Department, Azienda Ospedaliera di Padova, Padua, Italy
    Curr Opin Pulm Med 11:363-7. 2005
    ..The present review focuses on the relative values of low-molecular-weight heparin and subcutaneous unfractionated heparin for the initial treatment of venous thromboembolism...
  91. ncbi request reprint Screening for occult cancer in patients with idiopathic venous thromboembolism: yes
    A Piccioli
    Department of Medical and Surgical Sciences, University of Padua, Italy
    J Thromb Haemost 1:2271-2. 2003
  92. ncbi request reprint Long-term clinical course of proximal deep venous thrombosis and detection of recurrent thrombosis
    P Prandoni
    Department of Clinical and Surgical Sciences, University of Padua, Italy
    Semin Thromb Hemost 27:9-13. 2001
    ..Recent data suggest that these patients can be safely managed with the use of serial compression ultrasonography...
  93. ncbi request reprint High versus low doses of unfractionated heparin for the treatment of superficial thrombophlebitis of the leg. A prospective, controlled, randomized study
    Antonio Marchiori
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University Hospital of Padua, Italy
    Haematologica 87:523-7. 2002
    ....
  94. ncbi request reprint Upper extremity deep venous thrombosis
    Enrico Bernardi
    Department of First Aid, Emergency Medicine and Observation, University Hospital of Padua, Padua, Italy
    Semin Thromb Hemost 32:729-36. 2006
    ..UEDVT should no longer be regarded as a rare and benign disease, as reported previously...
  95. ncbi request reprint Does hemophilia protect against atherosclerosis? A case-control study
    Franca Bilora
    Department of Medical and Surgical Sciences, 2nd Chair of Internal Medicine, University of Padua Medical School, Padua, Italy
    Clin Appl Thromb Hemost 12:193-8. 2006
    ..In all the examined districts, the mean IMT was significantly lower in patients with hemophilia than in controls. Hemophilia protects against asymptomatic atherosclerosis...
  96. ncbi request reprint Sex and anticoagulation in patients with idiopathic venous thromboembolism
    Vittorio Pengo
    Department of Cardiothoracic and Vascular Sciences, University of Padua 35128, Italy
    Lancet 368:342-3. 2006
  97. ncbi request reprint Inherited thrombophilia and venous thromboembolism
    Paolo Simioni
    Department of Medical and Surgical Sciences, University of Padua, Medical School, Padua, Italy
    Semin Thromb Hemost 32:700-8. 2006
    ....
  98. ncbi request reprint Double vena cava filter insertion in congenital duplicated inferior vena cava: a case report and literature review
    Maria Teresa Sartori
    Department of Medical and Surgical Sciences, University Hospital, Padua, Italy
    Haematologica 91:ECR30. 2006
    ..A filter had to be inserted in each vena cava to prevent pulmonary embolism. A review of the literature dealing with the few reported cases of filter insertion in congenital duplicated IVC is presented...
  99. ncbi request reprint From acute pulmonary embolism to chronic thromboembolic pulmonary hypertension
    Vittorio Pengo
    Clinical Cardiology, Department of Cardiac Thoracic and Vascular Sciences, University of Padua, School of Medicine, Padua, Italy
    Ital Heart J 6:830-3. 2005
    ..This procedure may be difficult when distal branches of pulmonary vascular tree are involved. In selected cases, alternative therapies may be the arterial pulmonary vessel angioplasty and lung transplantation...
  100. doi request reprint The postthrombotic syndrome
    Raffaele Pesavento
    Thromboembolic Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Via Giustiniani 2, Padua, Italy
    Intern Emerg Med 5:185-92. 2010
    ..However, when carefully supervised and instructed to wear proper ECS, more than 50% of patients either remain quiescent or improve during long-term follow-up...
  101. ncbi request reprint Heparin- induced thrombocytopenia occurring in the first trimester of pregnancy: successful treatment with lepirudin. A case report
    Anna Furlan
    University of Padua Medical School, Padova, Italy
    Haematologica 91:ECR40. 2006
    ....