Pier Paolo Pompa

Summary

Country: Italy

Publications

  1. doi request reprint Super-resolution fluorescence imaging of biocompatible carbon dots
    Godefroy Leménager
    Istituto Italiano di Tecnologia, Center for Bio Molecular Via Barsanti 73010, Arnesano Lecce, Italy
    Nanoscale 6:8617-23. 2014
  2. pmc A general mechanism for intracellular toxicity of metal-containing nanoparticles
    Stefania Sabella
    Istituto Italiano di Tecnologia, Center for Bio Molecular Via Barsanti, 73010 Arnesano Lecce, Italy
    Nanoscale 6:7052-61. 2014
  3. doi request reprint Nanosilver-based antibacterial drugs and devices: mechanisms, methodological drawbacks, and guidelines
    Loris Rizzello
    Istituto Italiano di Tecnologia IIT, Center for Bio Molecular Via Barsanti, 73010 Arnesano Lecce, Italy
    Chem Soc Rev 43:1501-18. 2014
  4. doi request reprint Colorimetric detection of human papilloma virus by double isothermal amplification
    Stefano Persano
    Istituto Italiano di Tecnologia IIT, Center for Bio Molecular Via Barsanti 73010 Arnesano, Lecce, Italy
    Chem Commun (Camb) 49:10605-7. 2013
  5. pmc Molecular response of Escherichia coli adhering onto nanoscale topography
    Loris Rizzello
    Center for Bio Molecular Nanotechnologies, Instituto Italiano di Via Barsanti, Arnesano, Lecce, 73010, Italy
    Nanoscale Res Lett 7:575. 2012
  6. ncbi request reprint In vivo assessment of CdSe-ZnS quantum dots: coating dependent bioaccumulation and genotoxicity
    A Galeone
    Istituto Italiano di Tecnologia IIT, Center for Bio Molecular Via Barsanti 73010, Arnesano, Lecce, Italy
    Nanoscale 4:6401-7. 2012
  7. doi request reprint Physical assessment of toxicology at nanoscale: nano dose-metrics and toxicity factor
    P P Pompa
    Center for Bio Molecular Nanotechnology, Italian Institute of Technology, Via Barsanti 1, 73010 Arnesano, Lecce, Italy
    Nanoscale 3:2889-97. 2011
  8. pmc Concentration-dependent, size-independent toxicity of citrate capped AuNPs in Drosophila melanogaster
    Giuseppe Vecchio
    Italian Institute of Technology, Center for Bio Molecular Arnesano Lecce, Italy
    PLoS ONE 7:e29980. 2012
  9. doi request reprint Monodispersed and size-controlled multibranched gold nanoparticles with nanoscale tuning of surface morphology
    Gabriele Maiorano
    Italian Institute of Technology, Center for Biomolecular Nanotechnology CBN, Via Barsanti 1, 73010 Arnesano, LE, Italy
    Nanoscale 3:2227-32. 2011
  10. doi request reprint Impact of nanoscale topography on genomics and proteomics of adherent bacteria
    Loris Rizzello
    Italian Institute of Technology, Center for Bio Molecular Nanotechnology, Via Barsanti 73010 Arnesano, Lecce, Italy
    ACS Nano 5:1865-76. 2011

Collaborators

  • Roberto Cingolani
  • Giuseppe Vecchio
  • Roberto Marotta
  • Giuseppe Bardi
  • Francesco Stellacci
  • Sam M Janes
  • Giuseppe Maruccio
  • Giovanni Bertoni
  • Ross Rinaldi
  • Ioannis Liakos
  • Jay L Nadeau
  • Virgilio Brunetti
  • Maria Ada Malvindi
  • Loris Rizzello
  • Stefania Sabella
  • Antonio Galeone
  • Elisa De Luca
  • Prakash Kshirsagar
  • Stefano Persano
  • Gabriele Maiorano
  • Paola Valentini
  • Valeria De Matteis
  • Athanassia Athanassiou
  • Ilker S Bayer
  • Barbara Sorce
  • Mauro Moglianetti
  • Ilaria Romano
  • Federica Degliangeli
  • Juergen Bartelmess
  • Godefroy Leménager
  • Roberto Fiammengo
  • Rosaria Brescia
  • A Galeone
  • Loretta Laureana Del Mercato
  • Tiziano Catelani
  • Saverio Francesco Retta
  • Deborah Pedone
  • Barbara Sartori
  • Heinz Amenitsch
  • Rosalia Bertorelli
  • Maria Summa
  • Fernando Brandi
  • Farouk Ayadi
  • Sachin Kote
  • Noura Al-Juffali
  • Angelo Signorelli
  • Emilio Parisini
  • George C Anyfantis
  • Valentina Nardone
  • Luis Echegoyen
  • Shiv Shankar Sangaru
  • Michele Becce
  • Ya Ping Sun
  • Randy P Carney
  • Osman M Bakr
  • Michele Baldrighi
  • Silvia Giordani
  • Joong Hyun Kim
  • Hicham Chibli
  • M A Malvindi
  • V Brunetti
  • Despina Fragouli
  • Maria Kalyva
  • Andrea Falqui
  • Luigi Martiradonna
  • Agnese Attanasio
  • Sangaru Shiv Shankar
  • Teresa Pellegrino
  • Riccardo Di Corato
  • Antonio Mario Tamburro
  • Antonio Della Torre

Detail Information

Publications26

  1. doi request reprint Super-resolution fluorescence imaging of biocompatible carbon dots
    Godefroy Leménager
    Istituto Italiano di Tecnologia, Center for Bio Molecular Via Barsanti 73010, Arnesano Lecce, Italy
    Nanoscale 6:8617-23. 2014
    ....
  2. pmc A general mechanism for intracellular toxicity of metal-containing nanoparticles
    Stefania Sabella
    Istituto Italiano di Tecnologia, Center for Bio Molecular Via Barsanti, 73010 Arnesano Lecce, Italy
    Nanoscale 6:7052-61. 2014
    ..Finally, we show that particles unable to release toxic ions (such as stably coated NPs, or diamond and silica NPs) are not harmful to intracellular environments...
  3. doi request reprint Nanosilver-based antibacterial drugs and devices: mechanisms, methodological drawbacks, and guidelines
    Loris Rizzello
    Istituto Italiano di Tecnologia IIT, Center for Bio Molecular Via Barsanti, 73010 Arnesano Lecce, Italy
    Chem Soc Rev 43:1501-18. 2014
    ....
  4. doi request reprint Colorimetric detection of human papilloma virus by double isothermal amplification
    Stefano Persano
    Istituto Italiano di Tecnologia IIT, Center for Bio Molecular Via Barsanti 73010 Arnesano, Lecce, Italy
    Chem Commun (Camb) 49:10605-7. 2013
    ..This method allows obtaining a fast response with a detection limit of 10 pM, avoiding the amplification of the target via traditional PCR. ..
  5. pmc Molecular response of Escherichia coli adhering onto nanoscale topography
    Loris Rizzello
    Center for Bio Molecular Nanotechnologies, Instituto Italiano di Via Barsanti, Arnesano, Lecce, 73010, Italy
    Nanoscale Res Lett 7:575. 2012
    ..At the same time, our findings highlight the possibility of designing nanoengineered substrates able to trigger specific bio-molecular effects, thus opening the perspective of smartly tuning bacterial behavior by biomaterial design...
  6. ncbi request reprint In vivo assessment of CdSe-ZnS quantum dots: coating dependent bioaccumulation and genotoxicity
    A Galeone
    Istituto Italiano di Tecnologia IIT, Center for Bio Molecular Via Barsanti 73010, Arnesano, Lecce, Italy
    Nanoscale 4:6401-7. 2012
    ....
  7. doi request reprint Physical assessment of toxicology at nanoscale: nano dose-metrics and toxicity factor
    P P Pompa
    Center for Bio Molecular Nanotechnology, Italian Institute of Technology, Via Barsanti 1, 73010 Arnesano, Lecce, Italy
    Nanoscale 3:2889-97. 2011
    ..This approach may pave the way to a systematic classification of nanomaterials, leading to important developments in risk assessment and regulatory approval, as well as in a wide range of nanomedicine applications...
  8. pmc Concentration-dependent, size-independent toxicity of citrate capped AuNPs in Drosophila melanogaster
    Giuseppe Vecchio
    Italian Institute of Technology, Center for Bio Molecular Arnesano Lecce, Italy
    PLoS ONE 7:e29980. 2012
    ..Interestingly, we found that, within the investigated experimental conditions, the toxic effects in the exposed organisms were directly related to the concentration of the AuNPs administered, irrespective of their size...
  9. doi request reprint Monodispersed and size-controlled multibranched gold nanoparticles with nanoscale tuning of surface morphology
    Gabriele Maiorano
    Italian Institute of Technology, Center for Biomolecular Nanotechnology CBN, Via Barsanti 1, 73010 Arnesano, LE, Italy
    Nanoscale 3:2227-32. 2011
    ..Such anisotropic nanostructures were demonstrated to be excellent candidates for SERS applications, showing significantly higher signals with respect to the standard spherical nanoparticles...
  10. doi request reprint Impact of nanoscale topography on genomics and proteomics of adherent bacteria
    Loris Rizzello
    Italian Institute of Technology, Center for Bio Molecular Nanotechnology, Via Barsanti 73010 Arnesano, Lecce, Italy
    ACS Nano 5:1865-76. 2011
    ..These data suggest that in depth investigations of the molecular processes of microorganisms adhering to surfaces are of great importance for the design of innovative biomaterials with active biological functionalities...
  11. doi request reprint Negligible particle-specific toxicity mechanism of silver nanoparticles: the role of Ag+ ion release in the cytosol
    Valeria De Matteis
    Istituto Italiano di Tecnologia, Center for Bio Molecular Arnesano Lecce, Italy
    Nanomedicine 11:731-9. 2015
    ..Cell death following the application of AgNPs is dose-dependent, and it is mostly due to Ag+ ions. Further in vivo studies should be performed to gain a comprehensive picture of AgNP-toxicity in mammals...
  12. doi request reprint InP/ZnS as a safer alternative to CdSe/ZnS core/shell quantum dots: in vitro and in vivo toxicity assessment
    Virgilio Brunetti
    Istituto Italiano di Tecnologia IIT, Center for Bio Molecular Via Barsanti, 73010 Arnesano, Lecce, Italy
    Nanoscale 5:307-17. 2013
    ..Since an almost identical amount of In(III) ions is observed to leach from the core of InP/ZnS QDs, their very low toxicity as revealed in this study hints at a much lower intrinsic toxicity of indium compared to cadmium...
  13. doi request reprint Nanotechnology tools for antibacterial materials
    Loris Rizzello
    Center for Bio Molecular Nanotechnology, Istituto Italiano di Tecnologia, Via Barsanti, 1 73010 Arnesano Lecce, Italy
    Nanomedicine (Lond) 8:807-21. 2013
    ..The advantages, drawbacks and limitations of such nanotechnologies are critically discussed in view of potential future applications...
  14. doi request reprint Controlled antiseptic release by alginate polymer films and beads
    Ioannis Liakos
    Center for Biomolecular Nanotechnologies, Istituto Italiano di Tecnologia UniLe, Via Barsanti, 73010 Arnesano, Lecce, Italy
    Carbohydr Polym 92:176-83. 2013
    ..A wide variety of applications are envisioned such as external and internal wound dressings with controlled antiseptic release, hygienic and protective packaging films for medical devices, and polymer beads as water disinfectants...
  15. pmc Toxicity assessment of silica coated iron oxide nanoparticles and biocompatibility improvement by surface engineering
    Maria Ada Malvindi
    Center for Biomolecular Istituto Italiano di Tecnologia, Arnesano, Italy
    PLoS ONE 9:e85835. 2014
    ..Our results indicate that surface engineering of Fe3O4/SiO2 NPs plays a key role in improving particles stability in biological environments reducing both cytotoxic and genotoxic effects. ..
  16. doi request reprint Effects of cell culture media on the dynamic formation of protein-nanoparticle complexes and influence on the cellular response
    Gabriele Maiorano
    Italian Institute of Technology, Center for Bio Molecular Nanotechnology, Via Barsanti 73010 Arnesano, Lecce, Italy
    ACS Nano 4:7481-91. 2010
    ..These results show that, beyond an in-depth NPs characterization before cellular experiments, a detailed understanding of the effects elicited by cell culture media on NPs is crucial for standardized nanotoxicology tests...
  17. doi request reprint SiO2 nanoparticles biocompatibility and their potential for gene delivery and silencing
    Maria Ada Malvindi
    Italian Institute of Technology, Center for Bio Molecular Via Barsanti, 73010, Arnesano, Lecce, Italy
    Nanoscale 4:486-95. 2012
    ..The results of this work indicate that monodisperse and stable SiO(2)NPs are not toxic, revealing their promising potential in various biomedical applications...
  18. doi request reprint Controlled antiseptic/eosin release from chitosan-based hydrogel modified fibrous substrates
    Ilaria Romano
    Smart Materials, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy
    Carbohydr Polym 131:306-14. 2015
    ..Due to its easy application on common passive commercial fibrous dressings such as gauzes and cotton fibers, the method can render them active dressings in a cost effective way. ..
  19. doi request reprint Absolute and direct microRNA quantification using DNA-gold nanoparticle probes
    Federica Degliangeli
    Center for Biomolecular Istituto Italiano di Tecnologia IIT, Via Barsanti, 73010 Arnesano, Lecce, Italy
    J Am Chem Soc 136:2264-7. 2014
    ..The possibility of direct and absolute quantification may significantly advance the use of microRNAs as biomarkers in the clinical praxis. ..
  20. doi request reprint Water-repellent cellulose fiber networks with multifunctional properties
    Ilker S Bayer
    Center for Biomolecular Nanotechnologies UNILE, Istituto Italiano di Tecnologia IIT, 73010 Lecce, Italy
    ACS Appl Mater Interfaces 3:4024-31. 2011
    ....
  21. doi request reprint Boron dipyrromethene (BODIPY) functionalized carbon nano-onions for high resolution cellular imaging
    Juergen Bartelmess
    Istituto Italiano di Tecnologia IIT, Nano Carbon Materials, Nanophysics Department, Via Morego 30, 16163 Genova, Italy
    Nanoscale 6:13761-9. 2014
    ..The presented results highlight CNOs as excellent platforms for biological and biomedical studies due to their low toxicity, efficient cellular uptake and low fluorescence quenching of attached probes. ..
  22. pmc A hybrid chimeric system for versatile and ultra-sensitive RNase detection
    Stefano Persano
    1 Istituto Italiano di Tecnologia, Center for Bio Molecular Via Barsanti, 73010 Arnesano Lecce, Italy 2 Università del Salento, Via Provinciale Monteroni, 73100 Lecce, Italy
    Sci Rep 5:9558. 2015
    ..e., blood and saliva) and in cell culture medium, highlighting its suitability as cheap and sensitive tool for the detection of RNase levels. ..
  23. doi request reprint Synthesis of fluorescent metal nanoparticles in aqueous solution by photochemical reduction
    Prakash Kshirsagar
    Istituto Italiano di Tecnologia, Center for Biomolecular Via Barsanti, I 73010 Arnesano, LE, Italy
    Nanotechnology 25:045601. 2014
    ..Both silver and gold nanoparticles synthesized by this method exhibited fluorescence properties and their use for cell imaging applications has been demonstrated...
  24. doi request reprint A Universal Polymerase Chain Reaction Developer
    Paola Valentini
    Istituto Italiano di Tecnologia IIT, Via Morego, 30, 16163, Genova, Italy
    Angew Chem Int Ed Engl 55:2157-60. 2016
    ..Our method is universal, instrument-free, and ultra-sensitive, as it could detect as low as 0.01 zeptomoles of HIV template DNA in an excess of interfering human genomic DNA. ..
  25. doi request reprint Platinum nanozymes recover cellular ROS homeostasis in an oxidative stress-mediated disease model
    Mauro Moglianetti
    Istituto Italiano di Tecnologia, Center for Biomolecular Nanotechnologies, Via Barsanti 73010 Arnesano, Lecce, Italy
    Nanoscale 8:3739-52. 2016
    ..Noteworthily, we found that Pt nanozymes can efficiently reduce ROS levels, completely restoring the cellular physiological homeostasis. ..
  26. pmc Charge transport and intrinsic fluorescence in amyloid-like fibrils
    Loretta Laureana Del Mercato
    National Nanotechnology Laboratory, Istituto Nazionale per la Fisica della Materia Consiglio Nazionale della Ricerche, University of Salento, Lecce, Italy
    Proc Natl Acad Sci U S A 104:18019-24. 2007
    ....