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| N PitsikasSummaryCountry: Italy Publications
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Publications
Duloxetine Eli Lilly & CoN Pitsikas
Boehringer Ingelheim, Via Lorenzini 8, Milan 20139, Italy
Curr Opin Investig Drugs 1:116-21. 2000..In August 1999, this prediction changed, and the expected launch date became 2001, with an 80% probability of reaching the market and sales peaking at US $150 million in 2012 [349228]...- Effects of cerestat and NBQX on functional and morphological outcomes in rat focal cerebral ischemiaN Pitsikas
Department of Biology, Boehringer Ingelheim Italia, S p A, Via Lorenzini 8, 20129, Milan, Italy
Pharmacol Biochem Behav 68:443-7. 2001.... - Effects of molsidomine on scopolamine-induced amnesia and hypermotility in the ratN Pitsikas
Department of Medical Pharmacology, Faculty of Medicine, University of Milan, Via Vanvitelli 32, 20129 Milan, Italy
Eur J Pharmacol 426:193-200. 2001..These results suggest that to some extent, the NO donor molsidomine is involved in memory processing... - The non-NMDA receptor antagonist NBQX does not affect rats performance in the object recognition taskNikolaos Pitsikas
Department of Medical Pharmacology, University of Milan, Milan, Italy
Pharmacol Res 45:43-6. 2002..All rats acquired similarly well the task. In conclusion, these results would support and broaden previous observations on the lack of major involvement of AMPA receptors in the rat working memory mechanisms... - Effects of the nitric oxide donor molsidomine on different memory components as assessed in the object-recognition task in the ratNikolaos Pitsikas
Department of Medical Pharmacology, University of Milan, Via Vanvitelli 32, 20129 Milan, Italy
Psychopharmacology (Berl) 162:239-45. 2002..Recently, NO involvement in learning and memory processes has been proposed. Compounds that inhibit NO synthase, the key synthesizing enzyme, may block cognition, while NO donors may facilitate it... - Molsidomine attenuates N(omega)-nitro-L-argininemethylester-induced deficits in a memory task in the ratNikolaos Pitsikas
Department of Medical Pharmacology, University of Milan, Via Vanvitelli 32, 20129 Milan, Italy
Eur J Pharmacol 452:83-6. 2002..Molsidomine, 4 mg/kg, antagonized the L-NAME-induced performance deficits. These results indicate that NO is involved in post-training memory processes... - Molsidomine antagonizes L-NAME-induced acquisition deficits in a recognition memory task in the ratNikolaos Pitsikas
Department of Medical Pharmacology, Medical School, University of Milan, Via Vanvitelli 32, 20129 Milan, Italy
Pharmacol Res 47:311-5. 2003..Molsidomine (2 and 4 mg kg(-1), i.p.) at 4 but not at 2 mg kg(-1), antagonized the L-NAME-induced performance deficits. These results indicate that NO is involved in the acquisition of a recognition memory task... - The GABAB receptor and recognition memory: possible modulation of its behavioral effects by the nitrergic systemN Pitsikas
Department of Medical Pharmacology, University of Milan, Via Vanvitelli 32, 20129 Milan, Italy
Neuroscience 118:1121-7. 2003..These results indicate a) that the GABA(B) receptor is involved in recognition memory and b) that an NO component modulates the effects of the GABA(B) receptor on learning and memory... 
Effects of sub-anesthetic doses of ketamine on rats' spatial and non-spatial recognition memoryN Pitsikas
Department of Pharmacology, School of Medicine, University of Thessaly, 22 Papakiriazi Str, Larissa, Greece
Neuroscience 154:454-60. 2008..The current results indicate that the non-competitive NMDA antagonist ketamine may modulate either spatial or non-spatial recognition memory...