P Periti

Summary

Country: Italy

Publications

  1. ncbi request reprint Current treatment of sepsis and endotoxaemia
    P Periti
    Department of Pharmacology, University of Florence, Firenze, Italy
    Expert Opin Pharmacother 1:1203-17. 2000
  2. ncbi request reprint Tissue distribution of cefotetan in patients with Crohn's disease
    T Mazzei
    Department of Preclinical and Clinical Pharmacology, University of Florence, Italy
    Chemotherapy 37:297-302. 1991
  3. ncbi request reprint Single-dose cefotetan vs. multiple-dose cefoxitin--antimicrobial prophylaxis in colorectal surgery. Results of a prospective, multicenter, randomized study
    P Periti
    Department of Preclinical and Clinical Pharmacology, University of Florence, Italy
    Dis Colon Rectum 32:121-7. 1989
  4. ncbi request reprint Prophylaxis in gynaecological and obstetric surgery: a comparative randomised multicentre study of single-dose cefotetan versus two doses of cefazolin
    P Periti
    Dipartimento di Farmacologia Preclinica e Clinica, University of Florence, Italy
    Chemioterapia 7:245-52. 1988
  5. ncbi request reprint Antibiotic-induced release of bacterial cell wall components in the pathogenesis of sepsis and septic shock: a review
    P Periti
    Department of Pharmacology, University of Florence, Italy
    J Chemother 10:427-48. 1998
  6. pmc Penetration of cefotetan into suction skin blister fluid and tissue homogenates in patients undergoing abdominal surgery
    T Mazzei
    Department of Pharmacology, University of Florence, Italy
    Antimicrob Agents Chemother 38:2221-3. 1994
  7. ncbi request reprint Selecting antibacterial agents for the control of surgical infection: mini-review
    P Periti
    Department of Pharmacology, University of Florence, Italy
    J Chemother 10:83-90. 1998
  8. ncbi request reprint Clarithromycin: pharmacokinetic and pharmacodynamic interrelationships and dosage regimen
    P Periti
    Department of Preclinical and Clinical Pharmacology, University of Florence, Italy
    J Chemother 11:11-27. 1999
  9. ncbi request reprint Pharmacokinetics of roxithromycin in renal and hepatic failure and drug interactions
    P Periti
    Department of Preclinical and Clinical Pharmacology, University of Florence, Italy
    J Antimicrob Chemother 20:107-12. 1987

Detail Information

Publications9

  1. ncbi request reprint Current treatment of sepsis and endotoxaemia
    P Periti
    Department of Pharmacology, University of Florence, Firenze, Italy
    Expert Opin Pharmacother 1:1203-17. 2000
    ....
  2. ncbi request reprint Tissue distribution of cefotetan in patients with Crohn's disease
    T Mazzei
    Department of Preclinical and Clinical Pharmacology, University of Florence, Italy
    Chemotherapy 37:297-302. 1991
    ..2 mg/l.h, respectively (p less than 0.05). Inflammation seems to facilitate the penetration of cefotetan into the intestinal wall of patients with Crohn's disease but above all, it increases the mean residence time in inflamed tissue...
  3. ncbi request reprint Single-dose cefotetan vs. multiple-dose cefoxitin--antimicrobial prophylaxis in colorectal surgery. Results of a prospective, multicenter, randomized study
    P Periti
    Department of Preclinical and Clinical Pharmacology, University of Florence, Italy
    Dis Colon Rectum 32:121-7. 1989
    ..05). The mean postoperative hospital stay was similar in both the cefoxitin and cefotetan groups (15.1 vs. 15.9 days). Both regimens were inadequate in preventing infections in the presence of severe contamination of the operative field...
  4. ncbi request reprint Prophylaxis in gynaecological and obstetric surgery: a comparative randomised multicentre study of single-dose cefotetan versus two doses of cefazolin
    P Periti
    Dipartimento di Farmacologia Preclinica e Clinica, University of Florence, Italy
    Chemioterapia 7:245-52. 1988
    ..Cefotetan mean tissue concentrations in gynaecological organs were higher than those of cefazolin (25.5-44.8 vs. 7.4-9.5 mg/kg).(ABSTRACT TRUNCATED AT 250 WORDS)..
  5. ncbi request reprint Antibiotic-induced release of bacterial cell wall components in the pathogenesis of sepsis and septic shock: a review
    P Periti
    Department of Pharmacology, University of Florence, Italy
    J Chemother 10:427-48. 1998
    ....
  6. pmc Penetration of cefotetan into suction skin blister fluid and tissue homogenates in patients undergoing abdominal surgery
    T Mazzei
    Department of Pharmacology, University of Florence, Italy
    Antimicrob Agents Chemother 38:2221-3. 1994
    ..These data show that the determination of beta-lactam concentrations by the tissue homogenate method may seriously underestimate the actual antibiotic levels in extracellular fluid...
  7. ncbi request reprint Selecting antibacterial agents for the control of surgical infection: mini-review
    P Periti
    Department of Pharmacology, University of Florence, Italy
    J Chemother 10:83-90. 1998
    ..Current chemotherapy is able to check serious postoperative infectious complications by reducing the risk of septic shock with use of a glycopeptide-aminoglycoside-betalactam combination together with anti-inflammatory drugs...
  8. ncbi request reprint Clarithromycin: pharmacokinetic and pharmacodynamic interrelationships and dosage regimen
    P Periti
    Department of Preclinical and Clinical Pharmacology, University of Florence, Italy
    J Chemother 11:11-27. 1999
    ..This paper reviews pharmacokinetic and pharmacodynamic characteristics of clarithromycin, examining the potential impact of these properties on the dose and the optimal interval between administrations...
  9. ncbi request reprint Pharmacokinetics of roxithromycin in renal and hepatic failure and drug interactions
    P Periti
    Department of Preclinical and Clinical Pharmacology, University of Florence, Italy
    J Antimicrob Chemother 20:107-12. 1987
    ..Potential pharmacokinetic drug interactions that involve roxithromycin are very few and concern only disopyramide and theophylline. Theophylline concentrations should be monitored if the pretreatment blood level is greater than 15 mg/l...