Ilaria Peluso

Summary

Affiliation: INRAN
Location: Rome, Italy

Publications

  1. ncbi Modulation of apoptosis and improved redox metabolism with the use of a new antioxidant formula
    Luciana Mosca
    Department of Biochemical Sciences, Faculty of Medicine, University of Rome La Sapienza, P le Aldo Moro 5, 00185 Rome, Italy
    Biochem Pharmacol 63:1305-14. 2002
  2. ncbi Lactobacillus paracasei subsp. paracasei B21060 suppresses human T-cell proliferation
    Ilaria Peluso
    Dipartimento di Medicina Interna, Universita Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Infect Immun 75:1730-7. 2007
  3. ncbi Bacteria and mucosal immunity
    Giovanni Monteleone
    Department of Internal Medicine, Gastroenterology Unit, Tor Vergata University, Rome, Italy
    Dig Liver Dis 38:S256-60. 2006
  4. ncbi IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis
    Roberta Caruso
    Department of Internal Medicine and Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, University of Rome Tor Vergata, Rome, Italy
    J Immunol 178:5957-65. 2007
  5. ncbi Flavonoids as anti-inflammatory agents
    Mauro Serafini
    Antioxidant Research Laboratory, INRAN, Via Ardeatina 546, 00178 Rome, Italy
    Proc Nutr Soc 69:273-8. 2010
  6. ncbi Modulation of plasma non enzimatic antioxidant capacity (NEAC) by plant foods: the role of polyphenols
    M Serafini
    Antioxidant Research Laboratory at the Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
    Curr Top Med Chem 11:1821-46. 2011
  7. ncbi High fat meal increase of IL-17 is prevented by ingestion of fruit juice drink in healthy overweight subjects
    Ilaria Peluso
    Antioxidant Research Laboratory, INRAN Via Ardeatina 546, 00178 Rome, Italy
    Curr Pharm Des 18:85-90. 2012
  8. ncbi Lymphocytes as internal standard in oxidative burst analysis by cytometry: a new data analysis approach
    Ilaria Peluso
    Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione INRAN, Rome, Italy
    J Immunol Methods 379:61-5. 2012
  9. ncbi A functional role for interleukin-21 in promoting the synthesis of the T-cell chemoattractant, MIP-3alpha, by gut epithelial cells
    Roberta Caruso
    Dipartimento di Medicina Interna e Centro di Eccellenza, Studio delle Malattie Complesse e Multifattoriali, Universita Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Gastroenterology 132:166-75. 2007
  10. ncbi IL-21 counteracts the regulatory T cell-mediated suppression of human CD4+ T lymphocytes
    Ilaria Peluso
    Dipartimento di Medicina Interna, Universita Tor Vergata, Via Montpellier 1, Rome, Italy
    J Immunol 178:732-9. 2007

Collaborators

Detail Information

Publications21

  1. ncbi Modulation of apoptosis and improved redox metabolism with the use of a new antioxidant formula
    Luciana Mosca
    Department of Biochemical Sciences, Faculty of Medicine, University of Rome La Sapienza, P le Aldo Moro 5, 00185 Rome, Italy
    Biochem Pharmacol 63:1305-14. 2002
    ..The clinical potential of this strategy in the treatment of diseases with an elevated commitment to apoptosis should be explored...
  2. ncbi Lactobacillus paracasei subsp. paracasei B21060 suppresses human T-cell proliferation
    Ilaria Peluso
    Dipartimento di Medicina Interna, Universita Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Infect Immun 75:1730-7. 2007
    ..The data show that L. paracasei subsp. paracasei B21060 blocks T-cell growth, thus suggesting a mechanism by which these probiotics could interfere with T-cell-driven immune responses...
  3. ncbi Bacteria and mucosal immunity
    Giovanni Monteleone
    Department of Internal Medicine, Gastroenterology Unit, Tor Vergata University, Rome, Italy
    Dig Liver Dis 38:S256-60. 2006
    ..Emerging evidence also indicates that gut microflora can contribute to maintain the mucosal homeostasis by promoting the generation and/or expansion of counter-regulatory mechanisms...
  4. ncbi IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis
    Roberta Caruso
    Department of Internal Medicine and Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, University of Rome Tor Vergata, Rome, Italy
    J Immunol 178:5957-65. 2007
    ..These data indicate that IL-21 is overexpressed in Hp-infected gastric mucosa where it could contribute to increased epithelial gelatinase production...
  5. ncbi Flavonoids as anti-inflammatory agents
    Mauro Serafini
    Antioxidant Research Laboratory, INRAN, Via Ardeatina 546, 00178 Rome, Italy
    Proc Nutr Soc 69:273-8. 2010
    ..Human trials with appropriate placebo and pure flavonoid molecules are needed to clarify if flavonoids represent ancillary ingredients or key molecules involved in the anti-inflammatory properties of plant foods...
  6. ncbi Modulation of plasma non enzimatic antioxidant capacity (NEAC) by plant foods: the role of polyphenols
    M Serafini
    Antioxidant Research Laboratory at the Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
    Curr Top Med Chem 11:1821-46. 2011
    ..The available evidence from human intervention studies on the role of plant foods as modulators of plasma/serum NEAC and the involvement of PP will be presented and critically discussed...
  7. ncbi High fat meal increase of IL-17 is prevented by ingestion of fruit juice drink in healthy overweight subjects
    Ilaria Peluso
    Antioxidant Research Laboratory, INRAN Via Ardeatina 546, 00178 Rome, Italy
    Curr Pharm Des 18:85-90. 2012
    ..037). We provided, for the first time, evidence on the role of diet in modulating IL-17 production in healthy overweight subjects...
  8. ncbi Lymphocytes as internal standard in oxidative burst analysis by cytometry: a new data analysis approach
    Ilaria Peluso
    Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione INRAN, Rome, Italy
    J Immunol Methods 379:61-5. 2012
    ..In addition, this method is sensitive to differences in healthy subjects due to sub-pathological conditions, such as hypercholesterolemia...
  9. ncbi A functional role for interleukin-21 in promoting the synthesis of the T-cell chemoattractant, MIP-3alpha, by gut epithelial cells
    Roberta Caruso
    Dipartimento di Medicina Interna e Centro di Eccellenza, Studio delle Malattie Complesse e Multifattoriali, Universita Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Gastroenterology 132:166-75. 2007
    ..In this study we examined whether intestinal epithelial cells express IL-21R and respond to IL-21 in IBD...
  10. ncbi IL-21 counteracts the regulatory T cell-mediated suppression of human CD4+ T lymphocytes
    Ilaria Peluso
    Dipartimento di Medicina Interna, Universita Tor Vergata, Via Montpellier 1, Rome, Italy
    J Immunol 178:732-9. 2007
    ..Data indicate that IL-21 renders human CD4(+)CD25(-) T cells resistant to Treg-mediated suppression and suggest a novel mechanism by which IL-21 could augment T cell-activated responses in human immune-inflammatory diseases...
  11. ncbi Intestinal motility disorder induced by free radicals: a new model mimicking oxidative stress in gut
    Ilaria Peluso
    Department of Pharmacology of Natural Substances and General Physiology, La Sapienza University of Rome, Rome, Italy
    Pharmacol Res 46:533-8. 2002
    ..In conclusion, the results of the present study show that ABAP could be a useful tool to simulate early contractility dysfunctions mediated by oxidative stress...
  12. ncbi Role of the cholinergic system and of apamin-sensitive Ca2+-activated K+ channels on rabbit jejunum spontaneous activity and on the inhibitory effects of adrenoceptor agonists
    L Romanelli
    Dipartimento di Farmacologia delle Sostanze Naturali e Fisiologia Generale, University of Rome La Sapienza, University of Rome La Sapienza P.le A. Moro, 5-00185 Rome, Italy
    Auton Autacoid Pharmacol 23:105-15. 2003
    ..Released ACh inhibits myogenic activity and strongly antagonizes beta-adrenoceptor-induced APAM-insensitive inhibition but leaves alpha1 agonist-induced APAM-sensitive inhibition unchanged...
  13. ncbi Oxidant-induced pHi/Ca2+ changes in rat aortic smooth muscle cells. The role of atrial natriuretic peptide
    P De Vito
    Department of Biology, University of Rome 'Tor Vergata, Rome, Italy
    Mol Cell Biochem 252:353-62. 2003
    ....
  14. ncbi Effect on rat arterial blood pressure of chemically generated peroxyl radicals and protection by antioxidants
    Ilaria Peluso
    Department of Pharmacology of Natural Substances and General Physiology, La Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy
    J Nutr Biochem 15:323-7. 2004
    ..Other experiments are needed to clarify the role played by oxidative potentials on blood pressure and the mechanism of action of nutritional antioxidants...
  15. ncbi Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21
    G Monteleone
    Dipartimento di Medicina Interna, Universita Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Gut 55:1774-80. 2006
    ..We have previously shown that, in IBD, there is high production of interleukin (IL) 21, a T cell-derived cytokine, which enhances Th1 activity...
  16. ncbi Protease-activated receptor-2 activation in gastric cancer cells promotes epidermal growth factor receptor trans-activation and proliferation
    Roberta Caruso
    Department of Internal Medicine and the Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, University Tor Vergata of Rome, Rome, Italy
    Am J Pathol 169:268-78. 2006
    ..These data show that PAR-2 is overexpressed in GC and suggest a role of PAR-2 in EGFR trans-activation and cell growth...
  17. ncbi 5-aminosalicylic acid enhances anchorage-independent colorectal cancer cell death
    Daniele Fina
    Dipartimento di Medicina Interna, Cattedra di Gastroenterologia, e Centro di Eccellenza per lo studio delle malattie complesse e multifattoriali, , Via Montpellier, 1, 00133 Rome, Italy
    Eur J Cancer 42:2609-16. 2006
    ..In contrast, the 5-ASA-mediated Colo205 cell death is preventable by Bcl-2 over-expression. These data suggest a mechanism by which 5-ASA interferes with colon carcinogenesis...
  18. ncbi Interleukin-12 and Th1 immune response in Crohn's disease: pathogenetic relevance and therapeutic implication
    Ilaria Peluso
    World J Gastroenterol 12:5606-10. 2006
    ....
  19. ncbi A new flow cytometry method to measure oxidative status: the Peroxidation of Leukocytes Index Ratio (PLIR)
    Ilaria Peluso
    Agricultural Research Council CRA, ex National Institute for Food and Nutrition Research INRAN, Rome, Italy
    J Immunol Methods 390:113-20. 2013
    ..A complex relationship between immune system and metabolic pathway exists and can induce oxidative stress. The objective of this study was to design a new methodology allowing the measurement of oxidative status of leukocytes...
  20. ncbi Oxidative stress in atherosclerosis development: the central role of LDL and oxidative burst
    Ilaria Peluso
    Functional Food and Metabolic Stress Prevention Program, Agricultural Research Council CRA, ex National Institute for Food and Nutrition Research INRAN, Rome, Italy
    Endocr Metab Immune Disord Drug Targets 12:351-60. 2012
    ..Understanding the relationship between oxLDL and leukocyte oxidative burst helps to explain the involvement of innate immune responses in the early phases of atherosclerosis. The present review focuses on this interplay...