Palareti G, Legnani C, Cosmi B, Guazzaloca G, Cini M, Mattarozzi S. Poor anticoagulation quality in the first 3 months after unprovoked venous thromboembolism is a risk factor for long-term recurrence. J Thromb Haemost. 2005;3:955-61 pubmed
..5) during the first 3 months of treatment is associated with higher D-dimer values measured during OAT and after its interruption and is a significant risk factor for late VTE recurrence. ..
Palareti G, Cosmi B, Legnani C, Tosetto A, Brusi C, Iorio A, et al
. D-dimer testing to determine the duration of anticoagulation therapy. N Engl J Med. 2006;355:1780-9 pubmed
..The optimal course of anticoagulation in patients with a normal D-dimer level has not been clearly established. (ClinicalTrials.gov number, NCT00264277 [ClinicalTrials.gov].). ..