Gualtiero Palareti

Summary

Country: Italy

Publications

  1. ncbi [Current criteria to determine the duration of anticoagulant therapy]
    Gualtiero Palareti
    U O di Angiologia e Malattie della Coagulazione Marino Golinelli, Azienda Ospedaliero Universitaria di Bologna, Policlinico S Orsola Malpighi, Bologna
    Recenti Prog Med 98:603-6. 2007
  2. ncbi Predicting the risk of recurrence of venous thromboembolism
    Gualtiero Palareti
    Department of Angiology and Blood Coagulation, University Hospital, S Orsola Malpighi, Via Albertoni 15, 40138 Bologna, Italy
    Curr Opin Hematol 11:192-7. 2004
  3. ncbi Assessment of mental ability in elderly anticoagulated patients: its reduction is associated with a less satisfactory quality of treatment
    G Palareti
    Department of Angiology and Blood Coagulation, University Hospital S Orsola Malpighi, Bologna, Italy
    Blood Coagul Fibrinolysis 8:411-7. 1997
  4. ncbi Poor anticoagulation quality in the first 3 months after unprovoked venous thromboembolism is a risk factor for long-term recurrence
    G Palareti
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    J Thromb Haemost 3:955-61. 2005
  5. ncbi Risks factors for highly unstable response to oral anticoagulation: a case-control study
    Gualtiero Palareti
    Dipartimento di Angiologia e Malattie della Coagulazione Marino Golinelli, Policlinico S Orsola Malpighi, Universita di Bologna, Bologna, Italy
    Br J Haematol 129:72-8. 2005
  6. ncbi D-dimer testing to determine the duration of anticoagulation therapy
    Gualtiero Palareti
    Department of Angiology and Blood Coagulation, S Orsola Malpighi University Hospital, Bologna, Italy
    N Engl J Med 355:1780-9. 2006
  7. ncbi Diagnosis of deep vein thrombosis
    Gualtiero Palareti
    Department of Angiology and Blood Coagulation, University Hospital Saint Orsola Malpighi, Bologna, Italy
    Semin Thromb Hemost 32:659-72. 2006
  8. ncbi Risk of venous thromboembolism recurrence: high negative predictive value of D-dimer performed after oral anticoagulation is stopped
    Gualtiero Palareti
    Department of Angiology, Unità Ricerca Clinica sulla Trombofilia M Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Thromb Haemost 87:7-12. 2002
  9. ncbi A comparison of the safety and efficacy of oral anticoagulation for the treatment of venous thromboembolic disease in patients with or without malignancy
    G Palareti
    Dept Angiology and Blood Coagulation, University Hospital S Orsola Malpighi, Bologna, Italy
    Thromb Haemost 84:805-10. 2000
  10. ncbi Oral anticoagulation treatment in the elderly: a nested, prospective, case-control study
    G Palareti
    Department of Angiology, University Hospital S Orsola Malpighi, Bologna, Italy
    Arch Intern Med 160:470-8. 2000

Detail Information

Publications81

  1. ncbi [Current criteria to determine the duration of anticoagulant therapy]
    Gualtiero Palareti
    U O di Angiologia e Malattie della Coagulazione Marino Golinelli, Azienda Ospedaliero Universitaria di Bologna, Policlinico S Orsola Malpighi, Bologna
    Recenti Prog Med 98:603-6. 2007
    ..On the other hand, the optimal course of anticoagulation in subjects with normal D-dimer, whose risk of VTE recurrence is markedly lower, is not clearly established yet...
  2. ncbi Predicting the risk of recurrence of venous thromboembolism
    Gualtiero Palareti
    Department of Angiology and Blood Coagulation, University Hospital, S Orsola Malpighi, Via Albertoni 15, 40138 Bologna, Italy
    Curr Opin Hematol 11:192-7. 2004
    ..Our review focused on studies that evaluated different risk factors that might be useful to stratify patients into categories at different risk for recurrence...
  3. ncbi Assessment of mental ability in elderly anticoagulated patients: its reduction is associated with a less satisfactory quality of treatment
    G Palareti
    Department of Angiology and Blood Coagulation, University Hospital S Orsola Malpighi, Bologna, Italy
    Blood Coagul Fibrinolysis 8:411-7. 1997
    ..Anticoagulation clinics would be advised to assess mental abilities in elderly patients before starting OAT...
  4. ncbi Poor anticoagulation quality in the first 3 months after unprovoked venous thromboembolism is a risk factor for long-term recurrence
    G Palareti
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    J Thromb Haemost 3:955-61. 2005
    ..The aim of the study was to investigate whether the quality of oral anticoagulation therapy (OAT) is a long-term risk factor for recurrence of VTE after OAT interruption...
  5. ncbi Risks factors for highly unstable response to oral anticoagulation: a case-control study
    Gualtiero Palareti
    Dipartimento di Angiologia e Malattie della Coagulazione Marino Golinelli, Policlinico S Orsola Malpighi, Universita di Bologna, Bologna, Italy
    Br J Haematol 129:72-8. 2005
    ..9% vs.15.0%; P = 0.042). No differences were observed as regards the other variables. In conclusion, we found that high intra-individual variability in OAT control was multifactorial, but poor OAT comprehension was prevalent...
  6. ncbi D-dimer testing to determine the duration of anticoagulation therapy
    Gualtiero Palareti
    Department of Angiology and Blood Coagulation, S Orsola Malpighi University Hospital, Bologna, Italy
    N Engl J Med 355:1780-9. 2006
    ..The optimal duration of oral anticoagulation in patients with idiopathic venous thromboembolism is uncertain. Testing of D-dimer levels may play a role in the assessment of the need for prolonged anticoagulation...
  7. ncbi Diagnosis of deep vein thrombosis
    Gualtiero Palareti
    Department of Angiology and Blood Coagulation, University Hospital Saint Orsola Malpighi, Bologna, Italy
    Semin Thromb Hemost 32:659-72. 2006
    ..Some areas are still a matter of debate, such as the clinical relevance of isolated distal DVT and the diagnosis of suspected ipsilateral recurrence...
  8. ncbi Risk of venous thromboembolism recurrence: high negative predictive value of D-dimer performed after oral anticoagulation is stopped
    Gualtiero Palareti
    Department of Angiology, Unità Ricerca Clinica sulla Trombofilia M Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Thromb Haemost 87:7-12. 2002
    ..Only five idiopathic recurrences occurred in the 186 patients with consistently normal D-dimer. In conclusion, D-dimer has a high NPV for VTE recurrence when performed after OAT discontinuation...
  9. ncbi A comparison of the safety and efficacy of oral anticoagulation for the treatment of venous thromboembolic disease in patients with or without malignancy
    G Palareti
    Dept Angiology and Blood Coagulation, University Hospital S Orsola Malpighi, Bologna, Italy
    Thromb Haemost 84:805-10. 2000
    ..Safer and more effective anticoagulant therapy is needed for this challenging group of patients...
  10. ncbi Oral anticoagulation treatment in the elderly: a nested, prospective, case-control study
    G Palareti
    Department of Angiology, University Hospital S Orsola Malpighi, Bologna, Italy
    Arch Intern Med 160:470-8. 2000
    ..Whether elderly patients are at increased risk of complications during oral anticoagulant treatment (OAT) is still a matter of debate...
  11. ncbi Screening for activated protein C resistance before oral contraceptive treatment: a pilot study
    G Palareti
    Department of Angiology and Blood Coagulation, University Hospital S Orsola Malpighi, Bologna, Italy
    Contraception 59:293-9. 1999
    ..g., pregnancy and puerperium)...
  12. ncbi Predictive value of D-dimer test for recurrent venous thromboembolism after anticoagulation withdrawal in subjects with a previous idiopathic event and in carriers of congenital thrombophilia
    Gualtiero Palareti
    Dipartimento di Angiologia, Unità Ricerca Clinica sulla Trombofilia Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Circulation 108:313-8. 2003
    ..The aim of the present study was to assess the predictive value of D-dimer for recurrent VTE in subjects with a previous unprovoked event who are either carriers of inherited thrombophilia or not...
  13. doi The influence of factor V Leiden and G20210A prothrombin mutation on the presence of residual vein obstruction after idiopathic deep-vein thrombosis of the lower limbs
    Benilde Cosmi
    Department of Angiology Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, University of Bologna, Via Albertoni 15, Bologna, Italy
    Thromb Haemost 109:510-6. 2013
    ..Male sex and isolated DVT were significantly associated with RVO in all patients. In conclusion, male sex and isolated DVT are associated with RVO, while FVL and FII mutations are not significantly associated with RVO in this study...
  14. ncbi Comorbidities, alone and in combination with D-dimer, as risk factors for recurrence after a first episode of unprovoked venous thromboembolism in the extended follow-up of the PROLONG study
    Benilde Cosmi
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Thromb Haemost 103:1152-60. 2010
    ....
  15. doi A new warfarin dosing algorithm including VKORC1 3730 G > A polymorphism: comparison with results obtained by other published algorithms
    Michela Cini
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Via Albertoni, 15, 40138 Bologna, Italy
    Eur J Clin Pharmacol 68:1167-74. 2012
    ..We developed a new dosing algorithm including polymorphisms associated both with warfarin sensitivity and resistance in the Italian population, and its performance was compared with those of eight previously published algorithms...
  16. doi Usefulness of repeated D-dimer testing after stopping anticoagulation for a first episode of unprovoked venous thromboembolism: the PROLONG II prospective study
    Benilde Cosmi
    Department of Angiology and Blood Coagulation, Marino Golinelli University Hospital St Orsola Malpighi, Bologna, Italy
    Blood 115:481-8. 2010
    ..9; 95% CI: 2.1-30; P = .002). Repeated D-d testing after anticoagulation suspension for a first episode of unprovoked VTE could help tailor the duration of treatment. This trial is registered at http://clinicaltrials.gov as NCT00266045...
  17. ncbi D-dimer levels in combination with residual venous obstruction and the risk of recurrence after anticoagulation withdrawal for a first idiopathic deep vein thrombosis
    Benilde Cosmi
    Department of Angiology and Blood Coagulation M Golinelli, S Orsola Malpighi University Hospital, Bologna, Italy
    Thromb Haemost 94:969-74. 2005
    ....
  18. doi Thrombophilic risk factors and peripheral arterial disease severity
    Michelangelo Sartori
    U O di Angiologia e Malattie della Coagulazione Marino Golinelli, Azienda Ospedaliera di Bologna, Policlinico Sant Orsola Malpighi, Pad 2, Via Albertoni 15, Bologna, Italy
    Thromb Haemost 104:71-7. 2010
    ..These data suggest that the presence of two or more thrombophilic risk factors raise the likelihood of PAD being more severe, justifying the need for larger longitudinal studies...
  19. doi Evolution of untreated calf deep-vein thrombosis in high risk symptomatic outpatients: the blind, prospective CALTHRO study
    Gualtiero Palareti
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Thromb Haemost 104:1063-70. 2010
    ..7%; 95% CI: 1-13; p=0.049). Thrombotic evolution of untreated ICDVT in high-risk subjects may be relevant. Larger studies are needed to address this issue...
  20. doi Use of D-dimer testing to determine duration of anticoagulation, risk of cardiovascular events and occult cancer after a first episode of idiopathic venous thromboembolism: the extended follow-up of the PROLONG study
    Benilde Cosmi
    Department Angiology and Blood Coagulation Marino Golinelli, S Orsola Malpighi University Hospital, Via Albertoni, 15, Bologna, Italy
    J Thromb Thrombolysis 28:381-8. 2009
    ..The PROLONG study showed that D-dimer (D-d) testing could help tailor the duration of anticoagulation after idiopathic venous thromboembolism (VTE). In this report the initial 18 month study follow-up was extended for 1 year...
  21. ncbi Oral contraceptive use in women with poor anticoagulant response to activated protein C but not carrying the factor V Leiden mutation increases the risk of venous thrombosis
    Cristina Legnani
    Dept Angiology and Blood Coagulation, University Hospital S Orsola Malpighi, Via Massarenti, 9, 40138, Bologna, Italy
    Thromb Haemost 91:712-8. 2004
    ..Our data also showed that OC use in women with altered APC resistance further increased the risk of VTE in a way that exceeded the additive expectation...
  22. ncbi D-dimer and factor VIII are independent risk factors for recurrence after anticoagulation withdrawal for a first idiopathic deep vein thrombosis
    Benilde Cosmi
    Department of Angiology and Blood Coagulation Marino Golinelli, S Orsola Malpighi University Hospital, Bologna, Italy
    Thromb Res 122:610-7. 2008
    ..To assess the predictive value of D-dimer (D-d) and Factor VIII (FVIII) in combination for recurrent venous thromboembolism (VTE) after vitamin K antagonist (VKA) therapy suspension...
  23. doi Evaluation of a new automated panel of assays for the detection of anti-PF4/heparin antibodies in patients suspected of having heparin-induced thrombocytopenia
    Cristina Legnani
    Department Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Thromb Haemost 104:402-9. 2010
    ..Both the assays are reproducible (CVs <6%), rapid (turnaround time 30 minutes), automated, and semi-quantitative, and they can be run for single sample testing...
  24. doi Age and gender specific cut-off values to improve the performance of D-dimer assays to predict the risk of venous thromboembolism recurrence
    Cristina Legnani
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Via Albertoni, 15, 40138, Bologna, Italy
    Intern Emerg Med 8:229-36. 2013
    ..These method-specific cut-off values are being evaluated in the ongoing prospective management multicenter DULCIS study...
  25. ncbi Bleeding with anticoagulation therapy - who is at risk, and how best to identify such patients
    Gualtiero Palareti
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Via Albertoni, 15, 40138 Bologna, Italy
    Thromb Haemost 102:268-78. 2009
    ..The clinical prediction rules may help physicians stratify patients into categories of risk and thus to evaluate their individual risk/benefit ratio of starting or prolonging an anticoagulant treatment...
  26. ncbi Asymptomatic carriership of factor V Leiden and genotypes of the fibrinogen gene cluster
    Giovanna Marchetti
    Dipartimento di Biochimica e Biologia Molecolare, Universita di Ferrara, Unità di Ricerca Clinica sulla Trombofilia Marino Golinelli, Divisione di Angiologia, Azienda Ospedaliera di Bologna, Policlinico S Orsola Malpighi, Bologna, Italia
    Br J Haematol 121:632-8. 2003
    ..35 vs 2.69 +/- 0.41 g/l, P = 0.028) among the asymptomatic subjects. Our data suggest that, in the presence of inherited thrombophilia, frequent fibrinogen polymorphisms may interact to modulate the risk of venous thromboembolism...
  27. ncbi Abnormally short activated partial thromboplastin time values are associated with increased risk of recurrence of venous thromboembolism after oral anticoagulation withdrawal
    Cristina Legnani
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Br J Haematol 134:227-32. 2006
    ..The aPTT predictive value was independent of the presence of inherited thrombophilic alterations. In conclusion, abnormally short aPTT values are associated with a significantly increased risk of VTE recurrence...
  28. doi No early signs of atherosclerotic alterations in carriers of inherited thrombophilia
    Gualtiero Palareti
    Dept Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Eur J Intern Med 21:273-7. 2010
    ..Whether it is associated with increased risk of arterial disease is today a matter of debate. We aimed to look for early signs of atherosclerotic alterations in carriers of inherited thrombophilic alterations (ITA)...
  29. doi Different cut-off values of quantitative D-dimer methods to predict the risk of venous thromboembolism recurrence: a post-hoc analysis of the PROLONG study
    Cristina Legnani
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Via Albertoni 15, 40138 Bologna, Italy
    Haematologica 93:900-7. 2008
    ..The objective of this study was to evaluate the possible advantage of using quantitative D-dimer assays...
  30. ncbi Recurrence of ICH after resumption of anticoagulation with VK antagonists: CHIRONE study
    Daniela Poli
    From the Thrombosis Centre D P, Department of Heart and Vessels, Azienda Ospedaliero Universitaria Careggi Florence Department of Experimental and Clinical Medicine E A, University of Florence Department of Clinical Medicine F D, University of Insubria, Varese Haemostasis and Thrombosis Centre N E, Presidio Ospedaliero of Lecco Haemostasis and Thrombosis Centre a o Istituti Ospitalieri of Cremona S T Thrombosis Centre Civic Hospital Rimini E T and the Department of Angiology and Blood Coagulation Marino Golinelli G P, University Hospital S Orsola Malpighi, Bologna, Italy
    Neurology 82:1020-6. 2014
    ..To evaluate the risk of recurrent intracranial hemorrhage (ICH) in patients on vitamin K antagonists (VKAs) after a first episode of ICH...
  31. ncbi D-dimer to guide the duration of anticoagulation in patients with venous thromboembolism: a management study
    Gualtiero Palareti
    Angiology and Blood Coagulation, University Hospital of Bologna, Bologna, Italy
    Blood 124:196-203. 2014
    ..Serial D-dimer measurement is suitable in clinical practice for the identification of VTE patients in whom anticoagulation can be safely discontinued. This study was registered at clinicaltrials.gov as #NCT00954395. ..
  32. doi G1691A factor V and G20210A FII mutations, acute ischemic stroke of unknown cause, and patent foramen ovale
    Elisabetta Favaretto
    Department of Angiology and Blood Coagulation Marino Golinelli, S Orsola Malpighi University Hospital, 40138 Bologna, Italy
    Thromb Res 130:720-4. 2012
    ..We assessed the possible association between such inherited thrombophilic alterations and right-to-left shunt in patients with stroke...
  33. ncbi Role of family history in identifying women with thrombophilia and higher risk of venous thromboembolism during oral contraception
    Benilde Cosmi
    Division of Angiology, Cardiovascular Department, Unità di Ricerca Clinica sulla Trombofilia Marino Golinelli, University Hospital S Orsola Malpighi, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    Arch Intern Med 163:1105-9. 2003
    ..We evaluated the sensitivity and specificity of a family history of VTE to identify thrombophilia in women before OC and after venous thrombotic complications during OC...
  34. ncbi Reduced inhibition of activated prothrombin by heparin and venous thromboembolism: heparin resistance revisited
    Cristina Legnani
    Unità di Ricerca Clinica sulla Trombofilia Marino Golinelli, Divisione di Angiologia, Azienda Ospedaliera di Bologna, Policlinico S Orsola Malpighi, Italy
    Haematologica 87:182-8. 2002
    ..We evaluated a new test, based on prothrombin activation by Echis Carinatus snake venom in the absence/presence of unfractionated heparin, in patients with venous thromboembolism (VTE)...
  35. doi Old and new heparins
    Benilde Cosmi
    Dept Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Thromb Res 129:388-91. 2012
    ..The characteristics of these compounds are reviewed along with the description of their approved clinical uses...
  36. ncbi D-dimer testing to determine the duration of anticoagulant therapy
    Gualtiero Palareti
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Curr Opin Pulm Med 13:393-7. 2007
    ..Recent prospective observational studies show that D-dimer levels have a predictive value for the risk of recurrence. D-dimer testing may help in assessing the individual need for prolonged anticoagulation...
  37. ncbi Long-term efficacy of transcatheter patent foramen ovale closure on migraine headache with aura and recurrent stroke
    Alessandro Giardini
    Pediatric Cardiology and Adult Congenital Unit, University of Bologna, Bologna, Italy
    Catheter Cardiovasc Interv 67:625-9. 2006
    ..Background: Transcatheter PFO closure is associated with an early improvement of MHA, and a reduction or the risk of recurrent cerebral ischemia, but the long-term outcome after the procedure is unknown...
  38. ncbi Oral anticoagulant therapy in venous thromboembolism
    Benilde Cosmi
    Cardiovascular Department, Division of Angiology, S Orsola Malpighi University Hospital, Bologna, Italy
    Semin Vasc Med 3:303-14. 2003
    ..In patients with VTE and cancer, oral anticoagulation poses a higher risk of bleeding, and such patients are more prone to recurrences. Alternative treatment with LMWH could be safer and more effective in these patients...
  39. ncbi Risk of deep vein thrombosis: interaction between oral contraceptives and high factor VIII levels
    Cristina Legnani
    Dept Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Via Massarenti, 9 40138 Bologna, Italy
    Haematologica 89:1347-51. 2004
    ..High levels of factor VIII are a common risk factor for venous thromboembolism (VTE). The aim of this study was to evaluate the possible interaction between the presence of high factor VIII levels and oral contraceptive (OC) use...
  40. ncbi How I treat isolated distal deep vein thrombosis (IDDVT)
    Gualtiero Palareti
    Unit of Angiology and Blood Coagulation, University Hospital of Bologna, Bologna, Italy
    Blood 123:1802-9. 2014
    ..I review this issue, focusing on possible and suggested treatments in symptomatic IDDVT patients, and describe our current therapeutic approach to these patients. ..
  41. doi Clinical management of rivaroxaban-treated patients
    Gualtiero Palareti
    University Hospital of Bologna, Department Angiology and Blood Coagulation, Via Albertoni 15, 40138 Bologna, Italy
    Expert Opin Pharmacother 14:655-67. 2013
    ..This article is addressed to all professionals involved in the management of treated patients to highlight the characteristics of rivaroxaban and provide practical guidance on management of treated patients...
  42. ncbi Extended treatment for venous thromboembolism: how long is long enough?
    Benilde Cosmi
    Division of Angiology and Blood Coagulation, S Orsola Malpighi University Hospital, Via Albertoni 15, 40138 Bologna, Italy
    Curr Hematol Rep 3:375-81. 2004
    ..More recently, studies have indicated that other factors such as D-dimer levels after the discontinuation of oral anticoagulant therapy or the residual vein thrombosis could be additional predictive factors for recurrences...
  43. ncbi D-dimer, oral anticoagulation, and venous thromboembolism recurrence
    Benilde Cosmi
    Department of Angiology and Blood Coagulation Marino Golinelli, S Orsola Malpighi University Hospital, Bologna, Italy
    Semin Vasc Med 5:365-70. 2005
    ....
  44. ncbi Risk factors for recurrent events in subjects with superficial vein thrombosis in the randomized clinical trial SteFlux (Superficial Thromboembolism Fluxum)
    Benilde Cosmi
    Dept Angiology and Blood Coagulation Marino Golinelli, S Orsola Malpighi University Hospital, Bologna, Italy Electronic address
    Thromb Res 133:196-202. 2014
    ....
  45. doi Residual emboli on lung perfusion scan or multidetector computed tomography after a first episode of acute pulmonary embolism
    Benilde Cosmi
    Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Via Albertoni, 15, Bologna, Italy
    Intern Emerg Med 6:521-8. 2011
    ..Further studies are warranted in which the presence of residual embolism is detected by repetition of the same test that had been initially carried out...
  46. ncbi A new rapid bedside assay for quantitative testing of D-Dimer (Cardiac D-Dimer) in the diagnostic work-up for deep vein thrombosis
    Cristina Legnani
    UO di Angiologia, Dipartimento Cardiovascolare, Azienda Ospedaliera di Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    Thromb Res 111:149-53. 2003
    ..The place of this assay in the diagnostic strategy of DVT remains to be determined in prospective management studies...
  47. ncbi Repeated graft loss caused by recurrent hepatic artery thrombosis after liver transplantation
    Marco Vivarelli
    Dipartimento di Discipline Chirurgiche Rianimatorie e dei Trapianti, Chirurgia II, Policlinico S Orsola, Bologna, Italy
    Liver Transpl 9:629-31. 2003
    ..Recurrent HAT is an uncommon occurrence that, in our experience, was linked to specific thrombophilic conditions; careful screening of these disorders should be included in the pretransplant workup, and adequate prophylaxis is advisable...
  48. ncbi Psychological impact of testing for thrombophilic alterations
    Cristina Legnani
    Department of Angiology and Blood Coagulation Marino Golinelli, S Orsola Malpighi Hospital, Bologna, Italy
    Thromb Haemost 96:348-55. 2006
    ..The relationship between absence of adverse psychological reactions and quality of counseling program provided before and after TS should also be investigated...
  49. doi Multicenter evaluation of a new quantitative highly sensitive D-dimer assay, the Hemosil D-dimer HS 500, in patients with clinically suspected venous thromboembolism
    Cristina Legnani
    Dept Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Thromb Res 125:398-401. 2010
    ..We report on a multicenter evaluation of a new, automated, latex enhanced turbidimetric immunoassay [HemosIL D-Dimer HS 500, Instrumentation Laboratory (IL)]...
  50. doi Effects of unfractioned heparin and low-molecular-weight heparin on osteoprotegerin and RANKL plasma levels in haemodialysis patients
    Giuseppe Cianciolo
    Nephrology Dialysis and Renal Transplantation Unit, S Orsola University Hospital, and Department of Medicine and Public Health, University of Bologna, Bologna, Italy
    Nephrol Dial Transplant 26:646-52. 2011
    ....
  51. doi Update on the predictive value of D-dimer in patients with idiopathic venous thromboembolism
    Benilde Cosmi
    Dept Angiology and Blood Coagulation Marino Golinelli, University Hospital St Orsola Malpighi, Bologna, Italy
    Thromb Res 125:S62-5. 2010
    ..9% patient-years) (adjusted HR: 7.9; 95% CI:2.1-30; p = 0.002). These results indicate that repeated D-dimer testing after anticoagulation suspension may help tailor the individual duration of treatment after a first unprovoked VTE...
  52. ncbi Two years outcome of isolated distal deep vein thrombosis
    Michelangelo Sartori
    Department of Angiology and Blood Coagulation Marino Golinelli, S Orsola Malpighi University Hospital, 40138 Bologna, Italy Electronic address
    Thromb Res 134:36-40. 2014
    ..Isolated distal deep vein thrombosis (IDDVT) is frequently found in symptomatic outpatients, but its long term outcome is still uncertain...
  53. doi Risk of early recurrent fetal loss and levels of thrombin-activatable fibrinolysis inhibitor
    Cristina Legnani
    Dept Angiology and Blood Coagulation Marino Golinelli, University Hospital S Orsola Malpighi, Bologna, Italy
    Thromb Res 130:237-41. 2012
    ..Though thrombin-activatable fibrinolysis inhibitor (TAFI) may contribute to hypercoagulability during pregnancy, limited data are available on the role of TAFI in women with recurrent fetal loss...
  54. doi Thromboprophylaxis following cesarean delivery: one site prospective pilot study to evaluate the application of a risk score model
    Stefania Cavazza
    Department of Angiology and Blood Coagulation, S Orsola Malpighi University Hospital, Bologna, Italy
    Thromb Res 129:28-31. 2012
    ..Our aim was to assess the efficacy of a risk score model, established at our institution, in preventing CD-related VTE...
  55. ncbi Analysis of agreement between Duplex ultrasound scanning and arteriography in patients with lower limb artery disease
    Elisabetta Favaretto
    UO Angiologia e Malattie della Coagulazione Marino Golinelli, Policlinico S Orsola Malpighi, Bologna, Italy
    J Cardiovasc Med (Hagerstown) 8:337-41. 2007
    ..The present study aimed to investigate the agreement between Duplex scanning and angiography in the diagnosis of stenosis in lower limb artery disease...
  56. ncbi Coagulative disorders in human acute pancreatitis: role for the D-dimer
    Teresa Salomone
    Emergency Department, S Orsola Hospital, Bologna, Italy
    Pancreas 26:111-6. 2003
    ..We investigated coagulative disorders, particularly the role of the D-dimer, in acute pancreatitis where coagulation abnormalities related to disease severity are known to occur...
  57. doi Foetal cerebral hemispheric atrophy and porencephaly after intrauterine exposure to maternal warfarin for mechanical prosthetic heart valve
    Giuliana Simonazzi
    Department of Obstetrics and Gynecology, St Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
    Prenat Diagn 28:157-9. 2008
  58. ncbi Influence of age, sex and vitamin status on fasting and post-methionine load plasma homocysteine levels
    Simonetta Sassi
    Cardiovascular Department, Central Laboratory, University Hospital S Orsola Malpighi, Bologna, Italy
    Haematologica 87:957-64. 2002
    ..The secondary aim was to determine the reference values for FtHCy and PML-tHCy...
  59. doi Emerging drugs for venous thromboembolism
    Gualtiero Palareti
    University Hospital S Orsola Malpighi, Department of Angiology and Blood Coagulation Marino Golinelli, Via Albertoni 15, 40138 Bologna, Italy
    Expert Opin Emerg Drugs 15:107-17. 2010
    ..Anticoagulant (AC) drugs are necessary and effective for primary prevention, treatment of acute phase and prevention of recurrences. The currently available ACs have several drawbacks which have prompted the search for new drugs...
  60. doi Isolated distal deep vein thrombosis: what we know and what we are doing
    Gualtiero Palareti
    Department of Angiology and Blood Coagulation, University Hospital of Bologna, Italy
    J Thromb Haemost 10:11-9. 2012
    ..Specifically designed and adequately powered clinical studies addressing the issue of IDDVT need to be urgently undertaken...
  61. doi Assessing recurrence risk following acute venous thromboembolism: use of algorithms
    Daniela Poli
    Thrombosis Centre, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
    Curr Opin Pulm Med 19:407-12. 2013
    ..The aim of this review is to evaluate the risk factors for recurrence and the decisional algorithms available to guide patients' management...
  62. ncbi First-line therapy with thalidomide and dexamethasone in preparation for autologous stem cell transplantation for multiple myeloma
    Michele Cavo
    Institute of Hematology and Medical Oncology Seragnoli, Via Massarenti 9, 40138, Bologna, Italy
    Haematologica 89:826-31. 2004
    ....
  63. ncbi Comparison of results of percutaneous closure of patent foramen ovale for paradoxical embolism in patients with versus without thrombophilia
    Alessandro Giardini
    Pediatric Cardiology and Adult Congenital Unit, Department of Angiology, University of Bologna, Italy
    Am J Cardiol 94:1012-6. 2004
    ..Thus, transcatheter PFO closure is effective for preventing recurrences in patients who have a thrombophilia...
  64. ncbi A FV multiallelic marker detects genetic components of APC resistance contributing to venous thromboembolism in FV Leiden carriers
    Federico Mingozzi
    Dipartimento di Biochimica e Biologia Molecolare, Universita di Ferrara, Italy
    Thromb Haemost 89:983-9. 2003
    ..Our analysis indicates that frequent FV genetic components might contribute to shape the risk for VTE in FV Leiden carriers...
  65. ncbi Low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism
    Benilde Cosmi
    N Engl J Med 349:398-400; author reply 398-400. 2003
  66. ncbi Modulation of factor V levels in plasma by polymorphisms in the C2 domain
    Daniela Scanavini
    Department of Biochemistry and Molecular Biology, Ferrara University, Italy
    Arterioscler Thromb Vasc Biol 24:200-6. 2004
    ..Functional polymorphisms contributing to coagulation factor levels are preferential markers for association studies aimed at identifying prothrombic genetic components...
  67. ncbi Fibrin D-dimer testing for venous and arterial thrombotic disease
    Jan Jacques Michiels
    Goodheart Institute and Foundation, Hematology Hemostasis Thrombosis Science Center, Rotterdam, The Netherlands
    Semin Vasc Med 5:311-4. 2005
  68. ncbi Recurrence rate after a first venous thrombosis in patients with familial thrombophilia
    Carla Y Vossen
    Department of Clinical Epidemiology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Arterioscler Thromb Vasc Biol 25:1992-7. 2005
    ..We prospectively determined the recurrence rate after a first venous thrombotic event in patients with familial thrombophilia attributable to factor V Leiden or deficiencies of protein C, S, or antithrombin...
  69. ncbi Low-intensity oral anticoagulant plus low-dose aspirin during the first six months versus standard-intensity oral anticoagulant therapy after mechanical heart valve replacement: a pilot study of low-intensity warfarin and aspirin in cardiac prostheses (LI
    Vittorio Pengo
    Clinical Cardiology, Thrombosis Centre, University of Padova, Italy
    Clin Appl Thromb Hemost 13:241-8. 2007
    ..9 to 10.7) in Group A and 4.3% (95% CI 0.2 to 8.4) in Group B (p=0.6). Low-intensity treatment plus aspirin during the first six months after surgery appears to be as effective and safe as moderate-high-intensity anticoagulation...
  70. ncbi Factors associated with the timing of diagnosis of venous thromboembolism: results from the MASTER registry
    Walter Ageno
    U O Medicina I, Ospedale di Circolo, University of Insubria, Varese, Italy
    Thromb Res 121:751-6. 2008
    ..We aimed to evaluate the timing of diagnosis of deep vein thrombosis (DVT) and pulmonary embolism (PE) in Italian hospitals and to identify individual and clinical predictors of timely or delayed diagnosis...
  71. ncbi Warfarin anticoagulation in children made easier
    Gualtiero Palareti
    Thromb Res 118:667-9. 2006
  72. ncbi A commentary: to screen for calf DVT or not to screen? The highly variable practice among Italian centers highlights this important and still unresolved clinical option. Results from the Italian MASTER registry
    Gualtiero Palareti
    Thromb Haemost 99:241-4. 2008
  73. doi Clinical characteristics and management of cancer-associated acute venous thromboembolism: findings from the MASTER Registry
    Davide Imberti
    Thrombosis Center Emergency Department, Piacenza Hospital, Via Taverna 49, 29100 Piacenza, Italy
    Haematologica 93:273-8. 2008
    ..The aim of this paper was to provide information on clinical characteristics and management of acute venous thromboembolism in patients with cancer by means of a large prospective registry...
  74. ncbi The role of D-dimer and residual venous obstruction in recurrence of venous thromboembolism after anticoagulation withdrawal in cancer patients
    Benilde Cosmi
    Haematologica 90:713-5. 2005
    ..RVO, determined by compression ultrasonography on the day of OAT suspension (T1), and abnormal D-d (cut-off value: 500 ng/mL), measured at T1 and 30+/-10 days afterwards, are independent risk factors for recurrent VTE in cancer patients...
  75. ncbi Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    Jack Ansell
    Department of Medicine, Boston University Medical Center, 88 East Newton Street, Boston, MA 02118, USA
    Chest 133:160S-198S. 2008
    ..Patient self-monitoring or self-management, however, is a choice made by patients and physicians that depends on many factors. We suggest that such therapeutic management be implemented where suitable (Grade 2B)...
  76. ncbi A multicenter evaluation of a new quantitative highly sensitive D-dimer assay for exclusion of venous thromboembolism
    Philippe de Moerloose
    Angiology and Haemostasis Division, University Hospital of Geneva and Faculty of Medicine, Geneva Switzerland
    Thromb Haemost 100:505-12. 2008
    ..Our data indicate that the performances of Innovance D-Dimer, regardless of the analyzer, are similar to the reference methods, and that this assay can be used for the exclusion of venous thromboembolic disease...
  77. ncbi Comparative evaluation of D-dimer assays for exclusion of deep venous thrombosis in symptomatic outpatients
    Wolfgang Engelhardt
    Clinical and Scientific Affairs, Dade Behring Marburg GmbH, P O Box 1149, Marburg 35001, Germany
    Thromb Res 112:25-32. 2003
    ..Among them, 100 had deep venous thrombosis. Results obtained for both assays show a good efficiency for exclusion of deep venous thrombosis with well-acceptable specificity...
  78. ncbi Transcatheter patent foramen ovale closure mitigates aura migraine headaches abolishing spontaneous right-to-left shunting
    Alessandro Giardini
    Pediatric Cardiology and Adult Congenital Unit, University of Bologna, Italy
    Am Heart J 151:922.e1-5. 2006
    ....
  79. ncbi Spontaneous large right-to-left shunt and migraine headache with aura are risk factors for recurrent stroke in patients with a patent foramen ovale
    Alessandro Giardini
    Pediatric Cardiology and Adult Congenital Unit, University of Bologna, Italy
    Int J Cardiol 120:357-62. 2007
    ..We sought to determine whether migraine headache with aura (MHA) and spontaneous large right-to-left (R-L) shunt are risk factors for recurrent cerebral ischemic events in cryptogenic stroke patients with a patent foramen ovale (PFO)...
  80. ncbi The MASTER registry on venous thromboembolism: description of the study cohort
    Giancarlo Agnelli
    Division of Internal and Cardiovascular Medicine Stroke Unit, University of Perugia, Via Gerardo Dottori, 06100, Perugia, Italy
    Thromb Res 121:605-10. 2008
    ..The aim of this multicenter registry (MASTER) was to prospectively collect data on the epidemiology and long-term clinical outcome of VTE in an unselected cohort of patients...
  81. ncbi Deep-vein thrombosis in patients with multiple myeloma receiving first-line thalidomide-dexamethasone therapy
    Michele Cavo
    Blood 100:2272-3. 2002