M Brignole

Summary

Affiliation: Ospedali del Tigullio
Country: Italy

Publications

  1. ncbi request reprint A new management of syncope: prospective systematic guideline-based evaluation of patients referred urgently to general hospitals
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
    Eur Heart J 27:76-82. 2006
  2. ncbi request reprint Lack of correlation between the responses to tilt testing and adenosine triphosphate test and the mechanism of spontaneous neurally mediated syncope
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
    Eur Heart J 27:2232-9. 2006
  3. doi request reprint New concepts in the assessment of syncope
    Michele Brignole
    Arrhythmologic Centre and Syncope Unit, Ospedali del Tigullio, Lavagna, Italy
    J Am Coll Cardiol 59:1583-91. 2012
  4. doi request reprint Symptom onset-to-balloon time and mortality in the first seven years after STEMI treated with primary percutaneous coronary intervention
    Daniela Rollando
    Department of Cardiology, Ospedali del Tigullio, Lavagna 16033, Italy
    Heart 98:1738-42. 2012
  5. doi request reprint Clinical evaluation of defibrillation testing in an unselected population of 2,120 consecutive patients undergoing first implantable cardioverter-defibrillator implant
    Michele Brignole
    Ospedali del Tigullio, Lavagna, Italy
    J Am Coll Cardiol 60:981-7. 2012
  6. doi request reprint Pacemaker therapy in patients with neurally mediated syncope and documented asystole: Third International Study on Syncope of Uncertain Etiology (ISSUE-3): a randomized trial
    Michele Brignole
    Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
    Circulation 125:2566-71. 2012
  7. ncbi request reprint Standardized-care pathway vs. usual management of syncope patients presenting as emergencies at general hospitals
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
    Europace 8:644-50. 2006
  8. ncbi request reprint Early application of an implantable loop recorder allows effective specific therapy in patients with recurrent suspected neurally mediated syncope
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
    Eur Heart J 27:1085-92. 2006
  9. doi request reprint Usefulness of echo-guided cardiac resynchronization pacing in patients undergoing "ablate and pace" therapy for permanent atrial fibrillation and effects of heart rate regularization and left ventricular resynchronization
    Michele Brignole
    Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
    Am J Cardiol 102:854-60. 2008
  10. ncbi request reprint The usage and diagnostic yield of the implantable loop-recorder in detection of the mechanism of syncope and in guiding effective antiarrhythmic therapy in older people
    Michele Brignole
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Via don Bobbio 25, 16033 Lavagna, Italy
    Europace 7:273-9. 2005

Detail Information

Publications87

  1. ncbi request reprint A new management of syncope: prospective systematic guideline-based evaluation of patients referred urgently to general hospitals
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
    Eur Heart J 27:76-82. 2006
    ..The guidelines of the European Society of Cardiology (ESC) define the current standard for the management of syncope, but are still incompletely applied in the clinical setting...
  2. ncbi request reprint Lack of correlation between the responses to tilt testing and adenosine triphosphate test and the mechanism of spontaneous neurally mediated syncope
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
    Eur Heart J 27:2232-9. 2006
    ....
  3. doi request reprint New concepts in the assessment of syncope
    Michele Brignole
    Arrhythmologic Centre and Syncope Unit, Ospedali del Tigullio, Lavagna, Italy
    J Am Coll Cardiol 59:1583-91. 2012
    ..The long-term effects of such a new health care model on the rate of diagnosis and survival await future studies...
  4. doi request reprint Symptom onset-to-balloon time and mortality in the first seven years after STEMI treated with primary percutaneous coronary intervention
    Daniela Rollando
    Department of Cardiology, Ospedali del Tigullio, Lavagna 16033, Italy
    Heart 98:1738-42. 2012
    ..To evaluate the consequence of treatment delay of primary percutaneous coronary intervention (PPCI) on long-term survival...
  5. doi request reprint Clinical evaluation of defibrillation testing in an unselected population of 2,120 consecutive patients undergoing first implantable cardioverter-defibrillator implant
    Michele Brignole
    Ospedali del Tigullio, Lavagna, Italy
    J Am Coll Cardiol 60:981-7. 2012
    ..The purpose of this study is to assess the effectiveness of defibrillation testing (DT) in patients undergoing implantable cardioverter-defibrillator (ICD) insertion...
  6. doi request reprint Pacemaker therapy in patients with neurally mediated syncope and documented asystole: Third International Study on Syncope of Uncertain Etiology (ISSUE-3): a randomized trial
    Michele Brignole
    Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
    Circulation 125:2566-71. 2012
    ..We wanted to determine whether pacing therapy reduces syncopal recurrences in patients with severe asystolic neurally mediated syncope...
  7. ncbi request reprint Standardized-care pathway vs. usual management of syncope patients presenting as emergencies at general hospitals
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
    Europace 8:644-50. 2006
    ..The study hypothesis was that a decision-making approach improves diagnostic yield and reduces resource consumption for patients with syncope who present as emergencies at general hospitals...
  8. ncbi request reprint Early application of an implantable loop recorder allows effective specific therapy in patients with recurrent suspected neurally mediated syncope
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
    Eur Heart J 27:1085-92. 2006
    ..This prospective multicentre observational study assessed the efficacy of specific therapy based on implantable loop recorder (ILR) diagnostic observations in patients with recurrent suspected neurally mediated syncope (NMS)...
  9. doi request reprint Usefulness of echo-guided cardiac resynchronization pacing in patients undergoing "ablate and pace" therapy for permanent atrial fibrillation and effects of heart rate regularization and left ventricular resynchronization
    Michele Brignole
    Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
    Am J Cardiol 102:854-60. 2008
    ..Minimizing LV dyssynchrony by means of optimized CRP yields an additional important benefit...
  10. ncbi request reprint The usage and diagnostic yield of the implantable loop-recorder in detection of the mechanism of syncope and in guiding effective antiarrhythmic therapy in older people
    Michele Brignole
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Via don Bobbio 25, 16033 Lavagna, Italy
    Europace 7:273-9. 2005
    ..To evaluate the usage and diagnostic yield of the implantable loop-recorder (ILR) in detection of the mechanism of syncope and in guiding therapy in patients aged >/=65 years and comparing them with those <65 years...
  11. ncbi request reprint Neurally-mediated syncope
    Michele Brignole
    Arrhythmologic Center, Department of Cardiology, Ospedali del Tigullio, Lavagna GE, Italy
    Ital Heart J 6:249-55. 2005
    ..The evidence fails to support the efficacy of any drug...
  12. ncbi request reprint Proposed electrocardiographic classification of spontaneous syncope documented by an implantable loop recorder
    Michele Brignole
    Department of Cardiology, Ospedali del Tigullio, 16032 Lavagna, Italy
    Europace 7:14-8. 2005
    ..Therefore, the proposed classification aims to group the observations into homogeneous patterns in order to define an acceptable standard useful for future studies and clinical practice...
  13. ncbi request reprint Comparative assessment of right, left, and biventricular pacing in patients with permanent atrial fibrillation
    M Brignole
    Department of Cardiology, Ospedali del Tigullio, Via don Bobbio, 16033 Lavagna, Italy
    Eur Heart J 26:712-22. 2005
    ..Left ventricular (LV) and biventricular (BiV) pacing are potentially superior to right ventricular (RV) apical pacing in patients undergoing atrioventricular (AV) junction ablation and pacing for permanent atrial fibrillation...
  14. ncbi request reprint Guidelines on management (diagnosis and treatment) of syncope-update 2004. Executive Summary
    Michele Brignole
    Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, 16033 Lavagna, Italy
    Eur Heart J 25:2054-72. 2004
  15. ncbi request reprint Guidelines on management (diagnosis and treatment) of syncope--update 2004
    Michele Brignole
    Europace 6:467-537. 2004
  16. ncbi request reprint Distinguishing syncopal from non-syncopal causes of fall in older people
    Michele Brignole
    Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
    Age Ageing 35:ii46-ii50. 2006
  17. pmc Diagnosis and treatment of syncope
    Michele Brignole
    Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, 16033 Lavagna, Italy
    Heart 93:130-6. 2007
  18. doi request reprint Predictors of clinical efficacy of 'Ablate and Pace' therapy in patients with permanent atrial fibrillation
    M Brignole
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, 16033 Lavagna, Italy
    Heart 98:297-302. 2012
    ..Design Prospective multicentre observational study. Setting Cardiology departments of 19 general hospitals in Italy, Spain and Greece...
  19. doi request reprint Cardiac resynchronization therapy in patients undergoing atrioventricular junction ablation for permanent atrial fibrillation: a randomized trial
    Michele Brignole
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, 16033 Lavagna, Italy
    Eur Heart J 32:2420-9. 2011
    ..We examined whether CRT was superior to conventional right ventricular (RV) pacing in reducing heart failure (HF) events...
  20. doi request reprint Syncope due to idiopathic paroxysmal atrioventricular block: long-term follow-up of a distinct form of atrioventricular block
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
    J Am Coll Cardiol 58:167-73. 2011
    ..We present data on patients with syncope due to paroxysmal atrioventricular (AV) block unexplainable in terms of currently known mechanisms...
  21. doi request reprint Prospective multicentre systematic guideline-based management of patients referred to the Syncope Units of general hospitals
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
    Europace 12:109-18. 2010
    ..Although an organizational model for syncope management facilities was proposed in the 2004 guidelines of the European Society of Cardiology (ESC), its implementation in clinical practice and its effectiveness are largely unknown...
  22. ncbi request reprint Experience with implantable loop recorders for recurrent unexplained syncope
    Michele Brignole
    Arrhythmologic Centre and Syncope Unit, Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
    Congest Heart Fail 14:7-13. 2008
    ....
  23. doi request reprint Resynchronization of the left ventricular contraction by tailored programming of right and left ventricular pacing
    Michele Brignole
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Via don Bobbio, 16033 Lavagna, Italy
    Europace 10:489-95. 2008
    ..The prerequisite and the rationale for the benefit of cardiac resynchronization therapy (CRT) is that it is able to resynchronize left ventricular (LV) walls that have a delayed activation...
  24. ncbi request reprint Defibrillation testing at the time of implantation of cardioverter defibrillator in the clinical practice: a nation-wide survey
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, 16033 Lavagna, Italy
    Europace 9:540-3. 2007
    ..We conducted a systematic nation-wide retrospective survey in order to determine the DT rate and its complications...
  25. ncbi request reprint Analysis of rhythm variation during spontaneous cardioinhibitory neurally-mediated syncope. Implications for RDR pacing optimization: an ISSUE 2 substudy
    M Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio, 16033 Lavagna, Italy
    Europace 9:305-11. 2007
    ..Little is known of the variations of the heart rate during spontaneous cardioinhibitory neurally-mediated syncope. Their knowledge has both academic and practical implications for the optimization of rate drop response (RDR) pacing mode...
  26. ncbi request reprint Pacing for neurally mediated syncope: is placebo powerless?
    M Brignole
    Department of Cardiology, Ospedali del Tigullio, Via don Bobbio, 16033 Lavagna, Italy
    Europace 9:31-3. 2007
    ....
  27. ncbi request reprint International study on syncope of uncertain aetiology 3 (ISSUE 3): pacemaker therapy for patients with asystolic neurally-mediated syncope: rationale and study design
    M Brignole
    Department of Cardiology, Ospedali del Tigullio, Via don Bobbio, 16033 Lavagna, Italy
    Europace 9:25-30. 2007
    ..Sample size and duration: A maximum of 710 patients are to be enrolled during an anticipated period of 2 years to allow randomization of 60 patients in the Pm ON arm and 60 in the Pm OFF arm (total 120)...
  28. ncbi request reprint Nonarrhythmic syncope documented by an implantable loop recorder (an ISSUE substudy)
    Michele Brignole
    Department of Cardiology, Ospedali Riuniti, Lavagna, Italy
    Am J Cardiol 90:654-7. 2002
  29. ncbi request reprint Rhythm versus rate control after ablation and pacing for paroxysmal atrial fibrillation: clinical implications of the PAF 2 trial
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 25, 16033 Lavagna, Italy
    Card Electrophysiol Rev 7:127-9. 2003
    ..Therefore, the results of PAF2 study are consistent with the drug trials comparing rhythm and rate control...
  30. ncbi request reprint Mechanism of syncope in patients with bundle branch block and negative electrophysiological test
    M Brignole
    Departments of Cardiology, Ospedali Riuniti, Lavagna, Italy
    Circulation 104:2045-50. 2001
    ..In patients with syncope and bundle branch block (BBB), syncope is suspected to be attributable to a paroxysmal atrioventricular (AV) block, but little is known of its mechanism when electrophysiological study is negative...
  31. ncbi request reprint Results and complications of the carotid sinus massage performed according to the "method of symptoms"
    Enrico Puggioni
    Department of Cardiology and Arrhythmologic Center, Ospedali Riuniti, Lavagna, Italy
    Am J Cardiol 89:599-601. 2002
  32. ncbi request reprint Isometric arm counter-pressure maneuvers to abort impending vasovagal syncope
    Michele Brignole
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
    J Am Coll Cardiol 40:2053-9. 2002
    ..We hypothesized that isometric arm exercises were able to increase blood pressure (BP) during the phase of impending vasovagal syncope and allow the patient to avoid losing consciousness...
  33. ncbi request reprint The application of a standardized strategy of evaluation in patients with syncope referred to three syncope units
    F Croci
    Department of Cardiology of Ospedali del Tigullio, Lavagna, Italy
    Europace 4:351-5. 2002
    ..The aim of the study was to evaluate the applicability of those guidelines in the 'real world' and their impact on the use of the tests...
  34. ncbi request reprint The hidden part of neurally mediated disease
    M Brignole
    Europace 4:339-42. 2002
  35. ncbi request reprint Sick sinus syndrome
    Michele Brignole
    Department of Cardiology and Arrhythmologic Centre, Ospedali Riuniti, Via don Bobbio, 16032 Lavagna, Italy
    Clin Geriatr Med 18:211-27. 2002
    ..Treatment should be aimed at controlling morbidity and relieving symptoms. Cardiac pacing is the most powerful therapy; physiologic pacing (atrial or dual-chamber) has been shown definitively to be superior to ventricular pacing...
  36. ncbi request reprint Randomized clinical trials of neurally mediated syncope
    Michele Brignole
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
    J Cardiovasc Electrophysiol 14:S64-9. 2003
    ..The evidence fails to support the efficacy of beta-blocking drugs. As yet there are insufficient data to support the use of any other pharmacologic therapy for vasovagal syncope...
  37. ncbi request reprint Adenosine-induced atrioventricular block in patients with unexplained syncope: the diagnostic value of ATP testing
    M Brignole
    Section of Arrhythmology, Ospedali Riuniti, Lavagna, Italy
    Circulation 96:3921-7. 1997
    ..We hypothesized that an increased susceptibility of the atrioventricular node to adenosine may, in some cases, play a role in the genesis of syncope...
  38. ncbi request reprint Assessment of atrioventricular junction ablation and VVIR pacemaker versus pharmacological treatment in patients with heart failure and chronic atrial fibrillation: a randomized, controlled study
    M Brignole
    Department of Cardiology and Arrhythmologic Center, Ospedali Riuniti, Lavagna, Italy
    Circulation 98:953-60. 1998
    ..Uncontrolled studies have suggested that atrioventricular junction ablation and pacemaker implantation have beneficial effects on quality of life in patients with chronic atrial fibrillation (AF)...
  39. doi request reprint Clinical predictors of cardiac syncope at initial evaluation in patients referred urgently to a general hospital: the EGSYS score
    A Del Rosso
    Department of Cardiology, Azienda USL 11 Empoli, Italy
    Heart 94:1620-6. 2008
    ..To develop, in patients referred for syncope to an emergency department (ED), a diagnostic score to identify those patients likely to have a cardiac cause...
  40. ncbi request reprint An evaluation of the strategy of maintenance of sinus rhythm by antiarrhythmic drug therapy after ablation and pacing therapy in patients with paroxysmal atrial fibrillation
    M Brignole
    Department of Cardiology and Arrhythmologic Center, Ospedali Riuniti, Lavagna, Italy
    Eur Heart J 23:892-900. 2002
    ..We compared a strategy that initially allowed patients to remain in atrial fibrillation with a strategy that initially attempted to restore and maintain sinus rhythm...
  41. ncbi request reprint A standardized conventional evaluation of the mechanism of syncope in patients with bundle branch block
    P Donateo
    Department of Cardiology, Ospedali Riuniti, Lavagna, Italy
    Europace 4:357-60. 2002
    ..The finding of bundle branch block in patients with syncope suggests that paroxysmal AV block may be the cause of syncope, even though its prevalence is unknown...
  42. pmc Thromboembolism after atrioventricular node ablation and pacing: long term follow up
    M Gasparini
    Department of Cardiology, Istituto Clinico Humanitas, 56 Rozzano, 20089 Milan, Italy
    Heart 82:494-8. 1999
    ..To assess the incidence of arterial embolic events in patients with high rate, drug resistant, severely symptomatic paroxysmal and chronic atrial fibrillation who have undergone atrioventricular (AV) node ablation and permanent pacing...
  43. ncbi request reprint Effects of long-term vasodilator therapy in patients with carotid sinus hypersensitivity
    M Brignole
    Section of Arrhythmology, Ospedali Riuniti, Lavagna, Italy
    Am Heart J 136:264-8. 1998
    ..In patients affected by carotid sinus hypersensitivity, long-term vasodilator therapy might increase the risk of syncopal episodes by reducing systolic blood pressure and venous return to the heart...
  44. ncbi request reprint Management of syncope referred urgently to general hospitals with and without syncope units
    M Brignole
    Department of Cardiology, Ospedale del Tigullio, Lavagna, Italy
    Europace 5:293-8. 2003
    ..We tested the hypothesis that management of patients with syncope admitted urgently to a general hospital may be influenced by the presence of an in-hospital structured syncope unit...
  45. ncbi request reprint Management of patients with syncope referred urgently to general hospitals
    M Disertori
    Department of Cardiology, Ospedale S Chiara, Trento, Italy
    Europace 5:283-91. 2003
    ..To evaluate the incidence and the strategy of management of syncope admitted urgently to a general hospital...
  46. ncbi request reprint The diagnostic value of ATP testing in patients with unexplained syncope
    M Brignole
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
    Europace 5:425-8. 2003
    ..A favourable outcome suggests a strategy of postponing treatment, in particular pacemaker therapy, until a definite diagnosis can be made by documenting a spontaneous syncopal relapse...
  47. pmc Clinical features of adenosine sensitive syncope and tilt induced vasovagal syncope
    M Brignole
    Arrhythmologic Centre, Ospedali Riuniti, Lavagna, Italy
    Heart 83:24-8. 2000
    ..To evaluate the possible relation between adenosine sensitive syncope and tilt induced vasovagal syncope...
  48. ncbi request reprint Update in the treatment of neurally-mediated syncope
    R Maggi
    Department of Cardiology and Arrhythmologic Centre, Tigullio Hospital, Lavagna, Italy
    Minerva Med 98:503-9. 2007
    ....
  49. ncbi request reprint A randomized, double-blind, placebo-controlled study of permanent cardiac pacing for the treatment of recurrent tilt-induced vasovagal syncope. The vasovagal syncope and pacing trial (SYNPACE)
    Antonio Raviele
    Department of Cardiology, Ospedale Umberto I, Via Circonvallazione 50, 30174 Mestre Venice, Italy
    Eur Heart J 25:1741-8. 2004
    ..We performed a randomized, double-blind, placebo-controlled study in order to ascertain if pacing therapy reduces the risk of syncope relapse...
  50. ncbi request reprint Incidence, diagnostic yield and safety of the implantable loop-recorder to detect the mechanism of syncope in patients with and without structural heart disease
    Alberto Solano
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Via don Bobbio 25, 16033 Lavagna, Italy
    Eur Heart J 25:1116-9. 2004
    ..To evaluate the incidence, diagnostic yield and safety of implantable loop recorders (ILRs) in patients with or without structural heart disease (SHD)...
  51. ncbi request reprint [Comparative study of results of catheter ablation in ventricular tachycardia of different etiologies]
    Roberto Maggi
    Dipartimento di Cardiologia, Ospedali del Tigullio Via Don Bobbio, 25 16033 Lavagna
    G Ital Cardiol (Rome) 7:754-60. 2006
    ..The aim of this study was to assess long-term results and adverse events in patients with ventricular tachycardia from different etiologies...
  52. ncbi request reprint Cardioinhibitory carotid sinus hypersensitivity predicts an asystolic mechanism of spontaneous neurally mediated syncope
    Roberto Maggi
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
    Europace 9:563-7. 2007
    ..We correlated the finding of cardioinhibitory carotid sinus hypersensitivity (CSH) with that observed during a spontaneous syncopal relapse by means of an implantable loop recorder (ILR)...
  53. ncbi request reprint Acute comparative effect of right and left ventricular pacing in patients with permanent atrial fibrillation
    Enrico Puggioni
    Ospedali del Tigullio, Lavagna, Italy
    J Am Coll Cardiol 43:234-8. 2004
    ..The effect seems to be equal in patients with both depressed and preserved systolic functions and in those with and without native left bundle branch block...
  54. ncbi request reprint Mechanism of syncope in patients with positive adenosine triphosphate tests
    Paolo Donateo
    Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
    J Am Coll Cardiol 41:93-8. 2003
    ....
  55. ncbi request reprint [Recent advances in the treatment of syncopal syndromes]
    Roberto Maggi
    Centro Aritmologico, Dipartimento di Cardiologia, Ospedali del Tigullio, Lavagna
    Recenti Prog Med 97:369-75. 2006
    ....
  56. ncbi request reprint Effects of right ventricular pacing on intra-left ventricular electromechanical activation in patients with native narrow QRS
    Gabriele Lupi
    Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy, and Department of Cardiology, University Hospital of Crete, Herakleion, Greece
    Am J Cardiol 98:219-22. 2006
    ..Although normal baseline intra-LV electromechanical activation cannot exclude the development of significant asynchrony during RV pacing, the presence of preimplant LV asynchrony predicts for a worsening of this detrimental effect...
  57. ncbi request reprint Efficacy and feasibility of isometric arm counter-pressure manoeuvres to abort impending vasovagal syncope during real life
    Francesco Croci
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Via don Bobbio, 16033 Lavagna, Italy
    Europace 6:287-91. 2004
    ..Isometric arm exercises are able to increase blood pressure during the phase of impending vasovagal syncope. We evaluated their efficacy and feasibility during daily life in a group of 29 consecutive patients affected by vasovagal syncopes...
  58. doi request reprint Treatment of persistent sinus bradycardia with intermittent symptoms: are guidelines clear?
    Paolo Alboni
    Division of Cardiology, Arrhythmologic Center, Ospedale Civile di Cento, 44042 Cento FE, Italy
    Europace 11:562-4. 2009
    ..Since in most cases the causal relationship between syncope and persistent SB appears very weak, 'reflex syncope with associated SB' appears to be the most appropriate diagnosis...
  59. ncbi request reprint Two unusual cases of coincident atrioventricular nodal reentrant tachycardia and ventricular tachycardia
    Nicola Bottoni
    Department of Cardiology, S Maria Nuova Hospital, Reggio Emailia, Italy
    Ital Heart J 6:765-70. 2005
    ..Both patients underwent successful radiofrequency ablation of all the types of tachycardia...
  60. ncbi request reprint Mechanism of syncope in patients with heart disease and negative electrophysiologic test
    Carlo Menozzi
    Department of Cardiology, Ospedale S Maria Nuova, Reggio Emilia, Italy
    Circulation 105:2741-5. 2002
    ..In patients with syncope and structural heart disease, syncope is suspected to be attributable to a primary cardiac arrhythmia, but little is known of its mechanism when electrophysiologic study is unremarkable...
  61. ncbi request reprint Relation of clinical presentation of syncope to the age of patients
    Attilio Del Rosso
    Department of Cardiology, Ospedale S Pietro Igneo, Fucecchio, Florence, Italy
    Am J Cardiol 96:1431-5. 2005
    ..The specificity of some features is high but these can be observed in only a minority of patients...
  62. ncbi request reprint Seven-year follow-up after catheter ablation of atrioventricular nodal re-entrant tachycardia
    Roberto Maggi
    Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy
    J Cardiovasc Med (Hagerstown) 7:39-44. 2006
    ..Nevertheless, there is little information available with respect to long-term results and the consequences of catheter ablation. The present study aimed to assess the long-term results (a minimum of 5 years) and clinical events...
  63. doi request reprint Improved arrhythmia detection in implantable loop recorders
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
    J Cardiovasc Electrophysiol 19:928-34. 2008
    ..This study evaluated a new ILR sensing and detection scheme for automatically detecting asystole, bradyarrhythmia, and tachyarrhythmia events, which is implemented in the next generation device (Reveal DX/XT)...
  64. ncbi request reprint [Guidelines on management (diagnosis and treatment) of syncope. Update 2004. Executive summary]
    Michele Brignole
    Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
    Rev Esp Cardiol 58:175-93. 2005
  65. ncbi request reprint Transient left ventricular apical ballooning syndrome: all that glitters is not apical
    Bernardo Cortese
    Servizio di Emondinamica, Ospedali del Tigullio Lavagna, Lavagna, Italy
    J Cardiovasc Med (Hagerstown) 8:934-6. 2007
    ..We add a small piece to the complicated puzzle represented by this syndrome...
  66. ncbi request reprint [The SMASH-VT trial]
    Claudio Tondo
    II Divisione di Cardiologia, Istituto di Ricerca Clinico Sperimentale per le Aritmie e lo Scompenso, Fondazione A Valentino, AO San Camillo Forlanini Università Cattolica del Sacro Cuore, Roma
    G Ital Cardiol (Rome) 9:303-8. 2008
  67. ncbi request reprint Early EPS/ICD strategy in survivors of acute myocardial infarction with severe left ventricular dysfunction on optimal beta-blocker treatment. The BEta-blocker STrategy plus ICD trial
    Antonio Raviele
    Cardiology Division, Ospedale Umberto I, Via Circonvallazione, 50 30170 Mestre Venezia, Italy
    Europace 7:327-37. 2005
    ..Previous studies have shown the benefits of such a strategy only in high-risk patients late after MI...
  68. ncbi request reprint [How is syncope studied in the Italian hospitals?]
    Angelo Bartoletti
    Task Force Associazione Italiana di Aritmologia e Cardiostimolazione, Modello organizzativo di Syncope Unit
    Ital Heart J Suppl 5:472-9. 2004
    ..The aim of this study was to evaluate how the main tests for the diagnostic assessment of syncope are currently performed in the Italian hospitals...
  69. ncbi request reprint Clinical spectrum of neurally mediated reflex syncopes
    Paolo Alboni
    Division of Cardiology and Section of Arrhythmology, Ospedale Civile, 44042 Cento FE, Italy
    Europace 6:55-62. 2004
    ..The clinical features of the various types of neurally mediated reflex syncope have not been systematically investigated and compared. We sought to assess and compare the clinical spectrum of neurally mediated reflex syncopes...
  70. ncbi request reprint Left ventricular mechanics during right ventricular apical or left ventricular-based pacing in patients with chronic atrial fibrillation after atrioventricular junction ablation
    Emmanuel N Simantirakis
    Cardiology Department, Heraklion University Hospital, PO Box 1352 Stavrakia, Heraklion, Crete, Greece
    J Am Coll Cardiol 43:1013-8. 2004
    ....
  71. ncbi request reprint Lower limb and abdominal compression bandages prevent progressive orthostatic hypotension in elderly persons: a randomized single-blind controlled study
    Cristian Podoleanu
    Cardiologie Clinica Medicala 4, Spitalul Clinic de Urgenta, University Hospital, Targu Mures, Romania
    J Am Coll Cardiol 48:1425-32. 2006
    ..This study sought to assess the efficacy of compression bandage of legs and abdomen in preventing hypotension and symptoms...
  72. ncbi request reprint Outcome after cavo-tricuspid isthmus ablation in patients with recurrent atrial fibrillation and drug-related typical atrial flutter
    Nicola Bottoni
    Unità Operativa di Cardiologia Interventistica, Dipartimento di Cardiologia, Azienda Ospedaliera S Maria Nuova, V Risorgimento 80, Reggio Emilia, Italy
    Am J Cardiol 94:504-8. 2004
    ..Even in those who had recurrences, there was a substantial reduction in the incidence of episodes, quality of life was improved, and hospitalizations decreased...
  73. ncbi request reprint [Guidelines in cardiac pacing and resynchronization therapy]
    Panos E Vardas
    Kardiol Pol 65:1449-87; discussion 1488-9. 2007
  74. doi request reprint Syncope management from emergency department to hospital
    Michele Brignole
    J Am Coll Cardiol 51:284-7. 2008
  75. ncbi request reprint Left ventricular electromechanical delay in patients with heart failure and normal QRS duration and in patients with right and left bundle branch block
    Luigi P Badano
    Cardiology Unit, Echo Lab, Department of Cardiopulmonary Sciences, A O Santa Maria della Misericordia, Piazzale S Maria della Misericordia 15, 33100 Udine, Italy
    Europace 9:41-7. 2007
    ....
  76. ncbi request reprint Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in collaboration with the European Heart Rhythm Association
    Panos E Vardas
    Department of Cardiology, Heraklion University Hospital, PO Box 1352 Stavrakia, GR 711 10 Heraklion Crete, Greece
    Eur Heart J 28:2256-95. 2007
  77. ncbi request reprint Syncope: is a diagnosis a diagnosis?
    David G Benditt
    J Am Coll Cardiol 41:791-4. 2003
  78. ncbi request reprint Efficacy of tilt training in the treatment of neurally mediated syncope. A randomized study
    Giovanni Foglia-Manzillo
    Department of Cardiology of Ospedale Valduce, Como, Italy
    Europace 6:199-204. 2004
    ..Because of poor compliance, tilt training appears to be a feasible treatment only for highly motivated patients, but not for the majority of patients with recurrent neurally mediated syncope...
  79. ncbi request reprint [Current concepts on syncope of uncertain etiology]
    Michele Brignole
    Recenti Prog Med 94:434-9. 2003
    ..The Implantable Loop Recorder is indicated in some cases in which diagnosis remains unexplained despite a complete work-up...
  80. ncbi request reprint The clinical utility and diagnostic value of the head-up tilt testing (HUT) protocol
    Attilio Del Rosso
    J Cardiovasc Electrophysiol 15:615; author reply 615-6. 2004
  81. ncbi request reprint Case 26-2005: loss of consciousness while jogging
    J Gert van Dijk
    N Engl J Med 354:209. 2006
  82. ncbi request reprint Viewpoint: Michele Brignole, MD, FESC. Some thoughts on unexplained syncope. Interview by Ingrid Torjesen, BSc
    Michele Brignole
    Circulation 115:f41-2. 2007
  83. ncbi request reprint Is a syncope a syncope?
    Michele Brignole
    Ital Heart J 4:145-7. 2003
  84. ncbi request reprint Vasovagal syncope and vasovagal disease
    Michele Brignole
    Hellenic J Cardiol 49:61-4. 2008
  85. ncbi request reprint Effectiveness of physical counterpressure maneuvers in preventing vasovagal syncope: the Physical Counterpressure Manoeuvres Trial (PC-Trial)
    Nynke van Dijk
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    J Am Coll Cardiol 48:1652-7. 2006
    ..In this study, we assessed the effectiveness of physical counterpressure maneuvers (PCM) in daily life...
  86. ncbi request reprint Is vasovagal syncope a disease?
    Paolo Alboni
    Division of Cardiology and Arrhythmologic Center, Ospedale Civile, Via Vicini 2, 44042 Cento FE, Italy
    Europace 9:83-7. 2007
    ..In these subjects, VVS appears as an expression of a pathological process, i.e. a disease, mainly related to a generalized involvement of the autonomic nervous system, which is not yet well-defined from a nosological point of view...
  87. doi request reprint Consensus document on antithrombotic therapy in the setting of electrophysiological procedures
    Jean Jacques Blanc
    Department of Cardiology, Hopital de la Cavale Blanche, Bd Tanguy Prigent, Brest 29200, France
    Europace 10:513-27. 2008