Paolo Rebulla

Summary

Affiliation: Ospedale Maggiore
Country: Italy

Publications

  1. doi request reprint Development of a biological resource center for cellular therapy and biobanking in a public polyclinic university hospital
    Paolo Rebulla
    Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, 20122 Milan, Italy
    Biologicals 36:79-87. 2008
  2. ncbi request reprint Ten-year quality control of a semiautomated procedure of cord blood unit volume reduction
    Lucilla Lecchi
    Center of Transfusion Medicine, Cellular Therapy and Cryobiology, IRCCS Fondazione Ospedale Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Transfusion 49:563-9. 2009
  3. ncbi request reprint A mini-review on platelet refractoriness
    Paolo Rebulla
    Centro Trasfusionale e di Immunologia dei Trapianti, Department of Transfusion Medicine, Tissue Repair and Transplant Coordination, Milan, Italy
    Haematologica 90:247-53. 2005
  4. doi request reprint Role of the blood service in cellular therapy
    Paolo Rebulla
    Centre of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Biologicals 40:218-21. 2012
  5. pmc Potential advantages of cell administration on the inflammatory response compared to standard ACE inhibitor treatment in experimental myocardial infarction
    Michele M Ciulla
    Istituto di Medicina Cardiovascolare, Centro di Fisiologia Clinica e Ipertensione, University of Milan, Italy
    J Transl Med 6:30. 2008
  6. doi request reprint Towards responsible cord blood banking models
    P Rebulla
    Milano Cord Blood Bank, Centre of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Cell Prolif 44:30-4. 2011
  7. doi request reprint Differential microRNA signature of human mesenchymal stem cells from different sources reveals an "environmental-niche memory" for bone marrow stem cells
    Enrico Ragni
    Cell Factory Franco Calori, Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via F Sforza 35, 20122 Milano, Italy
    Exp Cell Res 319:1562-74. 2013
  8. doi request reprint Differentiation and migration properties of human foetal umbilical cord perivascular cells: potential for lung repair
    Tiziana Montemurro
    Cell Factory, Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    J Cell Mol Med 15:796-808. 2011
  9. doi request reprint Myocardial blood flow and infarct size after CD133+ cell injection in large myocardial infarction with good recanalization and poor reperfusion: results from a randomized controlled trial
    Alessandro Colombo
    Cardiology Department, Luigi Sacco Hospital, Milan, Italy
    J Cardiovasc Med (Hagerstown) 12:239-48. 2011
  10. pmc Implementation and outcomes of a transfusion-related acute lung injury surveillance programme and study of HLA/HNA alloimmunisation in blood donors
    Laura Porretti
    Department of Regenerative Medicine, IRCCS Ca Granda Maggiore Policlinico Hospital Foundation, Milan, Italy
    Blood Transfus 10:351-9. 2012

Collaborators

Detail Information

Publications38

  1. doi request reprint Development of a biological resource center for cellular therapy and biobanking in a public polyclinic university hospital
    Paolo Rebulla
    Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, 20122 Milan, Italy
    Biologicals 36:79-87. 2008
    ....
  2. ncbi request reprint Ten-year quality control of a semiautomated procedure of cord blood unit volume reduction
    Lucilla Lecchi
    Center of Transfusion Medicine, Cellular Therapy and Cryobiology, IRCCS Fondazione Ospedale Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Transfusion 49:563-9. 2009
    ..Volume reduction of cord blood units decreases the cost of cryogenic storage. This study reports the analysis of a 10-year quality control program of a semiautomated cord blood volume reduction procedure...
  3. ncbi request reprint A mini-review on platelet refractoriness
    Paolo Rebulla
    Centro Trasfusionale e di Immunologia dei Trapianti, Department of Transfusion Medicine, Tissue Repair and Transplant Coordination, Milan, Italy
    Haematologica 90:247-53. 2005
    ..INFORMATION SOURCES. To review the frequency, diagnosis, management and cost of platelet refractoriness, particularly as described in English literature published during 2000-2004 and searched with Pubmed...
  4. doi request reprint Role of the blood service in cellular therapy
    Paolo Rebulla
    Centre of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Biologicals 40:218-21. 2012
    ....
  5. pmc Potential advantages of cell administration on the inflammatory response compared to standard ACE inhibitor treatment in experimental myocardial infarction
    Michele M Ciulla
    Istituto di Medicina Cardiovascolare, Centro di Fisiologia Clinica e Ipertensione, University of Milan, Italy
    J Transl Med 6:30. 2008
    ..Angiotensin Converting Enzyme inhibitors (ACE-I) are effective in reducing mortality and preventing left ventricular (LV) function deterioration after myocardial infarction...
  6. doi request reprint Towards responsible cord blood banking models
    P Rebulla
    Milano Cord Blood Bank, Centre of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Cell Prolif 44:30-4. 2011
    ..In this regard, current scientific evidence and prevalent opinions among expert clinicians support solidaristic cord blood donation for public use against the alternative option of commercial autologous cord blood storage...
  7. doi request reprint Differential microRNA signature of human mesenchymal stem cells from different sources reveals an "environmental-niche memory" for bone marrow stem cells
    Enrico Ragni
    Cell Factory Franco Calori, Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via F Sforza 35, 20122 Milano, Italy
    Exp Cell Res 319:1562-74. 2013
    ....
  8. doi request reprint Differentiation and migration properties of human foetal umbilical cord perivascular cells: potential for lung repair
    Tiziana Montemurro
    Cell Factory, Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    J Cell Mol Med 15:796-808. 2011
    ..The secretory profile exhibited by foetal HUCPC in the migration assay suggested a paracrine effect that could be exploited in various clinical conditions including lung disorders...
  9. doi request reprint Myocardial blood flow and infarct size after CD133+ cell injection in large myocardial infarction with good recanalization and poor reperfusion: results from a randomized controlled trial
    Alessandro Colombo
    Cardiology Department, Luigi Sacco Hospital, Milan, Italy
    J Cardiovasc Med (Hagerstown) 12:239-48. 2011
    ..Thus, we conducted a randomized controlled trial aimed at evaluating the effect of intracoronary administration of CD133 stem cells on myocardial blood flow and function in this setting...
  10. pmc Implementation and outcomes of a transfusion-related acute lung injury surveillance programme and study of HLA/HNA alloimmunisation in blood donors
    Laura Porretti
    Department of Regenerative Medicine, IRCCS Ca Granda Maggiore Policlinico Hospital Foundation, Milan, Italy
    Blood Transfus 10:351-9. 2012
    ..We investigated the incidence and aetiology of TRALI in Lombardy. Moreover, we determined the rate of HLA and HNA alloimmunisation and the HNA genotype in a cohort of local blood donors...
  11. doi request reprint What is beyond a qRT-PCR study on mesenchymal stem cell differentiation properties: how to choose the most reliable housekeeping genes
    Enrico Ragni
    Cell Factory Franco Calori, Center for Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
    J Cell Mol Med 17:168-80. 2013
    ....
  12. doi request reprint From pH to MALDI-TOF: hundreds of spotted opportunities?
    Paolo Rebulla
    Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, Italy
    J Proteomics 76:270-4. 2012
    ..This article is part of a Special Issue entitled: Integrated omics...
  13. doi request reprint Simultaneous characterization of progenitor cell compartments in adult human liver
    Laura Porretti
    Center of Transfusion Medicine, Cellular Therapy and Cryobiology, IRCCS Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Cytometry A 77:31-40. 2010
    ..We also optimized a flow cytometry approach that will be useful in exploring the contribution of these cells to the pathogenesis of liver disease...
  14. pmc Evidence of distinct tumour-propagating cell populations with different properties in primary human hepatocellular carcinoma
    Federico Colombo
    Experimental Hepatology Laboratory, Centre of Transfusion Medicine, Cellular Therapy and Cryobiology, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    PLoS ONE 6:e21369. 2011
    ..The aim of this study was to investigate and characterise tumour-propagating cell (TPC) compartments within human hepatocellular carcinoma (HCC)...
  15. pmc Identification of new hematopoietic cell subsets with a polyclonal antibody library specific for neglected proteins
    Monica Moro
    Fondazione Istituto Nazionale di Genetica Molecolare, INGM, Milan, Italy
    PLoS ONE 7:e34395. 2012
    ....
  16. ncbi request reprint Oct-4 expression in adult human differentiated cells challenges its role as a pure stem cell marker
    Stefano Zangrossi
    Cell Factory, Center for Transfusion Medicine, Cellular Therapy and Cryobiology, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via F Sforza 35, 20122 Milano, Italy
    Stem Cells 25:1675-80. 2007
    ..These unexpected findings may provide new insights into the role of Oct-4 in fully differentiated cells. Disclosure of potential conflicts of interest is found at the end of this article...
  17. ncbi request reprint Successful transfusion of Kp (a-b+) red cells incompatible for auto anti-Kpb
    Maria Antonietta Villa
    Centro Trasfusionale e di Immunologia dei Trapianti, IRCCS Ospedale Maggiore, Via F Sforza, 35, 20122 Milano Italy
    Haematologica 90:ECR07. 2005
  18. pmc Banking together. A unified model of informed consent for biobanking
    Elena Salvaterra
    Fondazione IRCCS Ospedale Maggiore Policlinico in Milano, Italy
    EMBO Rep 9:307-13. 2008
  19. ncbi request reprint [A new setting of opportunistic cardiovascular screening: from blood donation to preventive cardiology. Preliminary results of the Cardiorisk program]
    Marcella Longo
    Centro Trasfusionale e di Immunoematologia, Dipartimento di Medicina Rigenerativa, Fondazione Ospedale Maggiore Policlinico Mangiagalli e Regina Elena, Milano
    G Ital Cardiol (Rome) 11:578-83. 2010
    ..They also mentioned the concept of opportunistic screening for cardio- and cerebrovascular risk factors...
  20. pmc The Lombardy Rare Donor Programme
    Nicoletta Revelli
    Immunohaematology Reference Laboratory, Immunohaematology and Transfusion Centre, Milan, Italy
    Blood Transfus 12:s249-55. 2014
    ..During 2005 to 2012, Lombardy funded LORD-P with 14.1 million euros...
  21. doi request reprint Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review
    Katerina Pavenski
    Department of Laboratory Medicine, St Michael s Hospital, Toronto, Ontario, Canada Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Foundation Ca Granda Ospedale Maggiore Policlinico, Milan, Italy Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania Platelet Immunology Laboratory, Canadian Blood Services, Winnipeg, Manitoba, Canada Puget Sound Blood Center and University of Washington School of Medicine, Seattle, Washington Canadian Blood Services, Toronto, Ontario, Canada Departments of Medicine and Obstetric Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
    Transfusion 53:2230-42. 2013
    ....
  22. ncbi request reprint Molecular and phenotypical characterization of human amniotic fluid cells and their differentiation potential
    Tiziana Montemurro
    Cell Factory, Centro di Medicina Trasfusionale, Terapia Cellulare e Criobiologia, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
    Biomed Mater Eng 18:183-5. 2008
  23. ncbi request reprint Development of a mock hemopoietic stem cell component suitable for the validation of cryopreservation procedures
    Lucilla Lecchi
    Milano Cord Blood Bank, Center of Transfusion Medicine, Cellular Therapy and Cryobiology, IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Francesco Sforza 35, 20122 Milano, Italy
    Transfus Apher Sci 34:299-307. 2006
    ..7 degrees C and the automatic achievement in the chamber of a constant minimum temperature during supercooling (about -37 degrees C) with mean chamber loading volumes ranging from 231.8 to 1027.2mL...
  24. doi request reprint Platelet gel from cord blood: a novel tool for tissue engineering
    Valentina Parazzi
    Cell Factory, Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Platelets 21:549-54. 2010
    ..These findings suggest that CB PG can be a preferable tool for tissue engineering applications where high levels of VEGF and PDGF may be desirable...
  25. pmc Pleural tissue repair with cord blood platelet gel
    Lorenzo Rosso
    Thoracic Surgery and Lung Transplant Unit, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
    Blood Transfus 12:s235-42. 2014
    ..Prolonged air leak is the major cause of morbidity after pulmonary resection. In this study we used in vitro and in vivo experiments to investigate an innovative approach based on the use of human umbilical cord blood platelet gel...
  26. doi request reprint The role of PET with 13N-ammonia and 18F-FDG in the assessment of myocardial perfusion and metabolism in patients with recent AMI and intracoronary stem cell injection
    Massimo Castellani
    Department of Nuclear Medicine, Fondazione IRCCS Ca Granda, Milan, Italy
    J Nucl Med 51:1908-16. 2010
    ....
  27. ncbi request reprint Flow-cytometric approach to the prompt laboratory diagnosis of TRALI: a case report
    Laura Porretti
    Servizio Autonomo per il Prelievo e Trapianto di Organi e Tessuti, IRCCS Ospedale Maggiore Policlinico, Milan, Italy
    Eur J Haematol 73:295-9. 2004
    ..In this report we describe our flow-cytometry approach to the laboratory diagnosis of a case of TRALI in a recipient of fresh frozen plasma containing human leukocyte antigen (HLA) class II antibodies...
  28. ncbi request reprint A descriptive analysis of international transfusion practice and bleeding outcomes in patients with acute leukemia
    Nancy M Heddle
    Department of Medicine, McMaster University, Canadian Blood Services, Hamilton, Ontario, Canada, and the Transfusion and Transplant Immunology Center IRCCS, Maggiore Hospital, Milan, Italy
    Transfusion 46:903-11. 2006
    ..The purpose of this study was to provide a descriptive summary of data from PLT studies conducted in four countries and exploratory analyses to determine the relationship between bleeding and PLT count...
  29. ncbi request reprint Successful transfusion of Kp (a-b+) red cells incompatible for auto anti-Kp(b)
    Maria Antonietta Villa
    Centro Trasfusionale e di Immunologia dei Trapianti, IRCCS Ospedale Maggiore, Via F Sforza, 35, 20122 Milano, Italy
    Haematologica 90:ECR07. 2005
  30. ncbi request reprint Cell therapy: an evolutionary development of transfusion medicine
    Paolo Rebulla
    Centro Trasfusionale e di Immunologia dei Trapianti, Cell Factory Franco Calori, IRCCS Ospedale Maggiore, Milano, Italy
    Int J Cardiol 95:S38-42. 2004
  31. ncbi request reprint Clinical and histological characterization of liver disease in patients with transfusion-dependent beta-thalassemia. A multicenter study of 117 cases
    Daniele Prati
    Dept of Blood Transfusion and Transplantation Immunology, IRCCS Ospedale Maggiore, Milan, Italy
    Haematologica 89:1179-86. 2004
    ..We conducted a multicenter study within the Cooleycare Group to describe the clinical and histopathological features of liver disease in currently treated thalassemics...
  32. ncbi request reprint Endothelial colony forming capacity is related to C-reactive protein levels in healthy subjects
    Michele M Ciulla
    Istituto di Medicina Cardiovascolare, Centro di Fisiologia Clinica e Ipertensione, Universita di Milano, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, IRCCS, Italy
    Curr Neurovasc Res 3:99-106. 2006
    ..The EPC clonogenic potential seems to be related to hs-CRP and VEGF levels even in healthy population supporting the concept that these mediators are involved in physiological ECs function...
  33. ncbi request reprint Homing of peripherally injected bone marrow cells in rat after experimental myocardial injury
    Michele M Ciulla
    Istituto di Clinica Medica Generale e Terapia Medica, Centro di Fisiologia Clinica e Ipertensione, Universita di Milano, IRCCS Ospedale Maggiore di Milano, Milan, Italy
    Haematologica 88:614-21. 2003
    ....
  34. ncbi request reprint Correlation between perioperative blood transfusion and prognosis of patients subjected to surgery for stage I lung cancer
    Mario Nosotti
    Thoracic Surgery Unit, I R C C S Ospedale Maggiore Policlinico, Milan, Italy
    Chest 124:102-7. 2003
    ..It has been reported, but not proven, that perioperative blood transfusions have a detrimental effect on the survival of patients undergoing surgery for lung cancer...
  35. ncbi request reprint The risk of bleeding in thrombocytopenic patients with acute myeloid leukemia
    Kathryn Webert
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Haematologica 91:1530-7. 2006
    ..Patients with acute myeloid leukemia are at risk of bleeding. The risk factors for different severities of bleeding are poorly studied...
  36. ncbi request reprint Platelet transfusions
    David F Stroncek
    Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1184, USA
    Lancet 370:427-38. 2007
    ..We review commonly used platelet components, product modifications, transfusion practices, and adverse consequences of platelet transfusions...
  37. ncbi request reprint Factors associated with outcomes of unrelated cord blood transplant: guidelines for donor choice
    Eliane Gluckman
    Bone Marrow Transplant Unit and Eurocord Registry, Laboratory of Clinical Research on Cell Therapy, Saint Louis Hospital AP HP University Paris VII, Paris, France
    Exp Hematol 32:397-407. 2004
    ..Optimizing cord blood donor selection based mainly on cell dose and human leukocyte antigen (HLA) disparities may further improve results of unrelated cord blood transplants (UCBT)...
  38. ncbi request reprint Outcomes of an automated procedure for the selection of effective platelets for patients refractory to random donors based on cross-matching locally available platelet products
    Paolo Rebulla
    Centro Trasfusionale e di Immunologia dei Trapianti Department of Haematology, IRCCS Ospedale Maggiore, Milano Istituto Europeo di Oncologia, Milano, Italy
    Br J Haematol 125:83-9. 2004
    ..This programme enabled the rapid selection of effective platelets for refractory patients, from the local inventory...