Research Topics
Species | Paolo RebullaSummaryAffiliation: Ospedale Maggiore Country: Italy Publications
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Detail Information
Publications
Development of a biological resource center for cellular therapy and biobanking in a public polyclinic university hospitalPaolo Rebulla
Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, 20122 Milan, Italy
Biologicals 36:79-87. 2008....
Ten-year quality control of a semiautomated procedure of cord blood unit volume reductionLucilla Lecchi
Center of Transfusion Medicine, Cellular Therapy and Cryobiology, IRCCS Fondazione Ospedale Policlinico, Mangiagalli e Regina Elena, Milan, Italy
Transfusion 49:563-9. 2009..Volume reduction of cord blood units decreases the cost of cryogenic storage. This study reports the analysis of a 10-year quality control program of a semiautomated cord blood volume reduction procedure...
Role of the blood service in cellular therapyPaolo Rebulla
Centre of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
Biologicals 40:218-21. 2012....
Potential advantages of cell administration on the inflammatory response compared to standard ACE inhibitor treatment in experimental myocardial infarctionMichele M Ciulla
Istituto di Medicina Cardiovascolare, Centro di Fisiologia Clinica e Ipertensione, University of Milan, Italy
J Transl Med 6:30. 2008..Angiotensin Converting Enzyme inhibitors (ACE-I) are effective in reducing mortality and preventing left ventricular (LV) function deterioration after myocardial infarction...
A mini-review on platelet refractorinessPaolo Rebulla
Centro Trasfusionale e di Immunologia dei Trapianti, Department of Transfusion Medicine, Tissue Repair and Transplant Coordination, Milan, Italy
Haematologica 90:247-53. 2005..INFORMATION SOURCES. To review the frequency, diagnosis, management and cost of platelet refractoriness, particularly as described in English literature published during 2000-2004 and searched with Pubmed...
Towards responsible cord blood banking modelsP Rebulla
Milano Cord Blood Bank, Centre of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
Cell Prolif 44:30-4. 2011..In this regard, current scientific evidence and prevalent opinions among expert clinicians support solidaristic cord blood donation for public use against the alternative option of commercial autologous cord blood storage...
Differentiation and migration properties of human foetal umbilical cord perivascular cells: potential for lung repairTiziana Montemurro
Cell Factory, Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
J Cell Mol Med 15:796-808. 2011..The secretory profile exhibited by foetal HUCPC in the migration assay suggested a paracrine effect that could be exploited in various clinical conditions including lung disorders...
Myocardial blood flow and infarct size after CD133+ cell injection in large myocardial infarction with good recanalization and poor reperfusion: results from a randomized controlled trialAlessandro Colombo
Cardiology Department, Luigi Sacco Hospital, Milan, Italy
J Cardiovasc Med (Hagerstown) 12:239-48. 2011..Thus, we conducted a randomized controlled trial aimed at evaluating the effect of intracoronary administration of CD133 stem cells on myocardial blood flow and function in this setting...
Implementation and outcomes of a transfusion-related acute lung injury surveillance programme and study of HLA/HNA alloimmunisation in blood donorsLaura Porretti
Department of Regenerative Medicine, IRCCS Ca Granda Maggiore Policlinico Hospital Foundation, Milan, Italy
Blood Transfus 10:351-9. 2012..We investigated the incidence and aetiology of TRALI in Lombardy. Moreover, we determined the rate of HLA and HNA alloimmunisation and the HNA genotype in a cohort of local blood donors...
From pH to MALDI-TOF: hundreds of spotted opportunities?Paolo Rebulla
Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Foundation IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, Italy
J Proteomics 76:270-4. 2012..This article is part of a Special Issue entitled: Integrated omics...
Evidence of distinct tumour-propagating cell populations with different properties in primary human hepatocellular carcinomaFederico Colombo
Experimental Hepatology Laboratory, Centre of Transfusion Medicine, Cellular Therapy and Cryobiology, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
PLoS ONE 6:e21369. 2011..The aim of this study was to investigate and characterise tumour-propagating cell (TPC) compartments within human hepatocellular carcinoma (HCC)...
Simultaneous characterization of progenitor cell compartments in adult human liverLaura Porretti
Center of Transfusion Medicine, Cellular Therapy and Cryobiology, IRCCS Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
Cytometry A 77:31-40. 2010..We also optimized a flow cytometry approach that will be useful in exploring the contribution of these cells to the pathogenesis of liver disease...
Identification of new hematopoietic cell subsets with a polyclonal antibody library specific for neglected proteinsMonica Moro
Fondazione Istituto Nazionale di Genetica Molecolare, INGM, Milan, Italy
PLoS ONE 7:e34395. 2012....
Oct-4 expression in adult human differentiated cells challenges its role as a pure stem cell markerStefano Zangrossi
Cell Factory, Center for Transfusion Medicine, Cellular Therapy and Cryobiology, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via F Sforza 35, 20122 Milano, Italy
Stem Cells 25:1675-80. 2007..These unexpected findings may provide new insights into the role of Oct-4 in fully differentiated cells. Disclosure of potential conflicts of interest is found at the end of this article...
Successful transfusion of Kp (a-b+) red cells incompatible for auto anti-KpbMaria Antonietta Villa
Centro Trasfusionale e di Immunologia dei Trapianti, IRCCS Ospedale Maggiore, Via F. Sforza, 35, 20122 Milano (Italy
Haematologica 90:ECR07. 2005
Banking together. A unified model of informed consent for biobankingElena Salvaterra
Fondazione IRCCS Ospedale Maggiore Policlinico in Milano, Italy
EMBO Rep 9:307-13. 2008
[A new setting of opportunistic cardiovascular screening: from blood donation to preventive cardiology. Preliminary results of the Cardiorisk program]Marcella Longo
Centro Trasfusionale e di Immunoematologia, Dipartimento di Medicina Rigenerativa, Fondazione Ospedale Maggiore Policlinico Mangiagalli e Regina Elena, Milano
G Ital Cardiol (Rome) 11:578-83. 2010..They also mentioned the concept of opportunistic screening for cardio- and cerebrovascular risk factors...
Development of a mock hemopoietic stem cell component suitable for the validation of cryopreservation proceduresLucilla Lecchi
Milano Cord Blood Bank, Center of Transfusion Medicine, Cellular Therapy and Cryobiology, IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Francesco Sforza 35, 20122 Milano, Italy
Transfus Apher Sci 34:299-307. 2006..7 degrees C and the automatic achievement in the chamber of a constant minimum temperature during supercooling (about -37 degrees C) with mean chamber loading volumes ranging from 231.8 to 1027.2mL...
Molecular and phenotypical characterization of human amniotic fluid cells and their differentiation potentialTiziana Montemurro
Cell Factory, Centro di Medicina Trasfusionale, Terapia Cellulare e Criobiologia, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy
Biomed Mater Eng 18:183-5. 2008
Platelet gel from cord blood: a novel tool for tissue engineeringValentina Parazzi
Cell Factory, Center of Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy
Platelets 21:549-54. 2010..These findings suggest that CB PG can be a preferable tool for tissue engineering applications where high levels of VEGF and PDGF may be desirable...
What is beyond a qRT-PCR study on mesenchymal stem cell differentiation properties: how to choose the most reliable housekeeping genesEnrico Ragni
Cell Factory Franco Calori, Center for Transfusion Medicine, Cellular Therapy and Cryobiology, Department of Regenerative Medicine, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
J Cell Mol Med 17:168-80. 2013....
Flow-cytometric approach to the prompt laboratory diagnosis of TRALI: a case reportLaura Porretti
Servizio Autonomo per il Prelievo e Trapianto di Organi e Tessuti, IRCCS Ospedale Maggiore Policlinico, Milan, Italy
Eur J Haematol 73:295-9. 2004..In this report we describe our flow-cytometry approach to the laboratory diagnosis of a case of TRALI in a recipient of fresh frozen plasma containing human leukocyte antigen (HLA) class II antibodies...
A descriptive analysis of international transfusion practice and bleeding outcomes in patients with acute leukemiaNancy M Heddle
Department of Medicine, McMaster University, Canadian Blood Services, Hamilton, Ontario, Canada, and the Transfusion and Transplant Immunology Center IRCCS, Maggiore Hospital, Milan, Italy
Transfusion 46:903-11. 2006..The purpose of this study was to provide a descriptive summary of data from PLT studies conducted in four countries and exploratory analyses to determine the relationship between bleeding and PLT count...
The role of PET with 13N-ammonia and 18F-FDG in the assessment of myocardial perfusion and metabolism in patients with recent AMI and intracoronary stem cell injectionMassimo Castellani
Department of Nuclear Medicine, Fondazione IRCCS Ca Granda, Milan, Italy
J Nucl Med 51:1908-16. 2010....
Successful transfusion of Kp (a-b+) red cells incompatible for auto anti-Kp(b)Maria Antonietta Villa
Centro Trasfusionale e di Immunologia dei Trapianti, IRCCS Ospedale Maggiore, Via F. Sforza, 35, 20122 Milano, Italy
Haematologica 90:ECR07. 2005
Cell therapy: an evolutionary development of transfusion medicinePaolo Rebulla
Centro Trasfusionale e di Immunologia dei Trapianti, Cell Factory Franco Calori, IRCCS Ospedale Maggiore, Milano, Italy
Int J Cardiol 95:S38-42. 2004
Clinical and histological characterization of liver disease in patients with transfusion-dependent beta-thalassemia. A multicenter study of 117 casesDaniele Prati
Dept of Blood Transfusion and Transplantation Immunology, IRCCS Ospedale Maggiore, Milan, Italy
Haematologica 89:1179-86. 2004..We conducted a multicenter study within the Cooleycare Group to describe the clinical and histopathological features of liver disease in currently treated thalassemics...
Endothelial colony forming capacity is related to C-reactive protein levels in healthy subjectsMichele M Ciulla
Istituto di Medicina Cardiovascolare, Centro di Fisiologia Clinica e Ipertensione, Universita di Milano, Fondazione Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, IRCCS, Italy
Curr Neurovasc Res 3:99-106. 2006..The EPC clonogenic potential seems to be related to hs-CRP and VEGF levels even in healthy population supporting the concept that these mediators are involved in physiological ECs function...
Homing of peripherally injected bone marrow cells in rat after experimental myocardial injuryMichele M Ciulla
Istituto di Clinica Medica Generale e Terapia Medica, Centro di Fisiologia Clinica e Ipertensione, Universita di Milano, IRCCS Ospedale Maggiore di Milano, Milan, Italy
Haematologica 88:614-21. 2003....
Correlation between perioperative blood transfusion and prognosis of patients subjected to surgery for stage I lung cancerMario Nosotti
Thoracic Surgery Unit, I R C C S Ospedale Maggiore Policlinico, Milan, Italy
Chest 124:102-7. 2003..It has been reported, but not proven, that perioperative blood transfusions have a detrimental effect on the survival of patients undergoing surgery for lung cancer...
The risk of bleeding in thrombocytopenic patients with acute myeloid leukemiaKathryn Webert
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Haematologica 91:1530-7. 2006..Patients with acute myeloid leukemia are at risk of bleeding. The risk factors for different severities of bleeding are poorly studied...
Platelet transfusionsDavid F Stroncek
Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1184, USA
Lancet 370:427-38. 2007..We review commonly used platelet components, product modifications, transfusion practices, and adverse consequences of platelet transfusions...
Factors associated with outcomes of unrelated cord blood transplant: guidelines for donor choiceEliane Gluckman
Bone Marrow Transplant Unit and Eurocord Registry, Laboratory of Clinical Research on Cell Therapy, Saint Louis Hospital AP HP University Paris VII, Paris, France
Exp Hematol 32:397-407. 2004..Optimizing cord blood donor selection based mainly on cell dose and human leukocyte antigen (HLA) disparities may further improve results of unrelated cord blood transplants (UCBT)...
Outcomes of an automated procedure for the selection of effective platelets for patients refractory to random donors based on cross-matching locally available platelet productsPaolo Rebulla
Centro Trasfusionale e di Immunologia dei Trapianti Department of Haematology, IRCCS Ospedale Maggiore, Milano Istituto Europeo di Oncologia, Milano, Italy
Br J Haematol 125:83-9. 2004..This programme enabled the rapid selection of effective platelets for refractory patients, from the local inventory...
