D Ardissino

Summary

Affiliation: Ospedale Niguarda
Country: Italy

Publications

  1. ncbi Activation of the contact system and inflammation after thrombolytic therapy in patients with acute myocardial infarction
    Piera Angelica Merlini
    IV Division of Cardiology, Ospedale Niguarda, Milan, Italy
    Am J Cardiol 93:822-5. 2004
  2. ncbi Thrombocytopenia caused by abciximab or tirofiban and its association with clinical outcome in patients undergoing coronary stenting
    Piera Angelica Merlini
    Division of Cardiology, Ospedale Niguarda, Piazza Ospedale Maggiore 1, 20162 Milan, Italy
    Circulation 109:2203-6. 2004
  3. pmc Mitral supravalvular ring: a case report
    Walter Serra
    Cardiology Division, Heart Department, Azienda Ospedaliera, Universitaria Parma, Italy
    Cardiovasc Ultrasound 3:19. 2005
  4. ncbi Tissue-factor antigen and activity in human coronary atherosclerotic plaques
    D Ardissino
    Division of Cardiology, IRCCS Policlinico San Matteo, Pavia, Italy
    Lancet 349:769-71. 1997
  5. ncbi Thrombogenic potential of human coronary atherosclerotic plaques
    D Ardissino
    Division of Cardiology, Ospedale Maggiore and University of Parma, Italy
    Blood 98:2726-9. 2001
  6. ncbi Hemostatic markers and prognosis in ischemic heart disease
    P A Merlini
    A De Gasperis Cardiology Department, Hospital Niguarda Ca Granda, Milan, Italy
    Ital Heart J 2:499-501. 2001
  7. ncbi Effect of abciximab on prothrombin activation and thrombin generation in patients with acute myocardial infarction also receiving reteplase
    Piera Angelica Merlini
    Division of Cardiology, Ospedale Niguarda, Milan, Italy
    Am J Cardiol 93:195-8. 2004
  8. ncbi Effect of Abciximab on prothrombin activation and thrombin generation in acute coronary syndromes without ST-segment elevation: Global Utilization of Strategies to Open Occluded Coronary Arteries Trial IV in Acute Coronary Syndromes (GUSTO IV ACS) Italian
    Piera Angelica Merlini
    Division of Cardiology, Ospedale Niguarda, Milan, Italy
    Circulation 105:928-32. 2002
  9. ncbi In vivo thrombin generation and activity during and after intravenous infusion of heparin or recombinant hirudin in patients with unstable angina pectoris
    P A Merlini
    Division of Cardiology, Ospedale Niguarda Ca Granda, Milan, Italy
    Arterioscler Thromb Vasc Biol 20:2162-6. 2000
  10. ncbi Prognostic value of the admission electrocardiogram in acute coronary syndromes
    S Savonitto
    Department of Cardiology A De Gasperis, Ospedale Niguarda Ca Granda, Milan, Italy
    JAMA 281:707-13. 1999

Collaborators

Detail Information

Publications59

  1. ncbi Activation of the contact system and inflammation after thrombolytic therapy in patients with acute myocardial infarction
    Piera Angelica Merlini
    IV Division of Cardiology, Ospedale Niguarda, Milan, Italy
    Am J Cardiol 93:822-5. 2004
    ....
  2. ncbi Thrombocytopenia caused by abciximab or tirofiban and its association with clinical outcome in patients undergoing coronary stenting
    Piera Angelica Merlini
    Division of Cardiology, Ospedale Niguarda, Piazza Ospedale Maggiore 1, 20162 Milan, Italy
    Circulation 109:2203-6. 2004
    ....
  3. pmc Mitral supravalvular ring: a case report
    Walter Serra
    Cardiology Division, Heart Department, Azienda Ospedaliera, Universitaria Parma, Italy
    Cardiovasc Ultrasound 3:19. 2005
    ..Cineangiography and MRI both failed in reaching this objective, whereas, transesophageal echocardiography is the best method to identify this congenital heart disease. Using TEE the identification is not only possible but also easier...
  4. ncbi Tissue-factor antigen and activity in human coronary atherosclerotic plaques
    D Ardissino
    Division of Cardiology, IRCCS Policlinico San Matteo, Pavia, Italy
    Lancet 349:769-71. 1997
    ..Although plaque rupture or fissuring frequently occurs in atherosclerosis, only a small proportion of ruptured plaques develop thromboses...
  5. ncbi Thrombogenic potential of human coronary atherosclerotic plaques
    D Ardissino
    Division of Cardiology, Ospedale Maggiore and University of Parma, Italy
    Blood 98:2726-9. 2001
    ..The higher tissue factor content found in plaques obtained from patients with unstable coronary disease was associated with a local increase in thrombin generation, thus suggesting a link with the in vivo thrombogenicity of the plaque...
  6. ncbi Hemostatic markers and prognosis in ischemic heart disease
    P A Merlini
    A De Gasperis Cardiology Department, Hospital Niguarda Ca Granda, Milan, Italy
    Ital Heart J 2:499-501. 2001
    ..The results of these studies as well as the value and applicability of new prothrombotic markers in the clinical practice are discussed...
  7. ncbi Effect of abciximab on prothrombin activation and thrombin generation in patients with acute myocardial infarction also receiving reteplase
    Piera Angelica Merlini
    Division of Cardiology, Ospedale Niguarda, Milan, Italy
    Am J Cardiol 93:195-8. 2004
    ....
  8. ncbi Effect of Abciximab on prothrombin activation and thrombin generation in acute coronary syndromes without ST-segment elevation: Global Utilization of Strategies to Open Occluded Coronary Arteries Trial IV in Acute Coronary Syndromes (GUSTO IV ACS) Italian
    Piera Angelica Merlini
    Division of Cardiology, Ospedale Niguarda, Milan, Italy
    Circulation 105:928-32. 2002
    ..No data are available concerning the effect of abciximab on the in vivo markers of prothrombin activation and thrombin generation in patients with acute coronary syndromes without ST elevation...
  9. ncbi In vivo thrombin generation and activity during and after intravenous infusion of heparin or recombinant hirudin in patients with unstable angina pectoris
    P A Merlini
    Division of Cardiology, Ospedale Niguarda Ca Granda, Milan, Italy
    Arterioscler Thromb Vasc Biol 20:2162-6. 2000
    ..However, the inhibition of thrombin generation is not sustained, and after 1 month, the majority of patients have biochemical signs of increased thrombin generation...
  10. ncbi Prognostic value of the admission electrocardiogram in acute coronary syndromes
    S Savonitto
    Department of Cardiology A De Gasperis, Ospedale Niguarda Ca Granda, Milan, Italy
    JAMA 281:707-13. 1999
    ..The presence of ischemic changes on electrocardiogram (ECG) correlates with poorer outcomes in patients with acute chest pain...
  11. ncbi Risk of intracranial haemorrhage with combined fibrinolytic and glycoprotein IIb/IIIa inhibitor therapy in acute myocardial infarction. Dichotomous response as a function of age in the GUSTO V trial
    S Savonitto
    Department of Cardiology, Niguarda Hospital, Milan, Italy
    Eur Heart J 24:1807-14. 2003
    ....
  12. ncbi Tissue factor in human coronary atherosclerotic plaques
    D Ardissino
    Division of Cardiology, I R C C S Policlinico San Matteo and University of Pavia, Piazza Golgi 1, 27100, Pavia, Italy
    Clin Chim Acta 291:235-40. 2000
    ..Variations in tissue factor content and activity may be responsible for the different thrombotic responses to human coronary atherosclerotic plaque rupture...
  13. ncbi Laboratory markers of hypercoagulability
    M L Rossi
    A De Gasperis Cardiology Department, Hospital Niguarda Ca Granda, Milan, Italy
    Ital Heart J 2:490-4. 2001
    ..The significance of these new assays and their role in defining a hypercoagulable state in different conditions are analyzed...
  14. ncbi Effect of transdermal nitroglycerin or N-acetylcysteine, or both, in the long-term treatment of unstable angina pectoris
    D Ardissino
    Division of Cardiology IRCCS Policlinico San Matteo, Pavia, Italy
    J Am Coll Cardiol 29:941-7. 1997
    ..This study was designed to evaluate whether the addition of transdermal nitroglycerin or oral N-acetylcysteine, or both, to conventional medical therapy improves the natural history of unstable angina pectoris...
  15. doi The association of factor V Leiden with myocardial infarction is replicated in 1880 patients with premature disease
    P M Mannucci
    Centro Emofilia e Trombosi A Bianchi Bonomi, Scientific Direction, IRCCS Fondazione Cà Granda Ospedale Maggiore, Universita degli Studi di Milano, Milan, Italy
    J Thromb Haemost 8:2116-21. 2010
    ....
  16. ncbi Clinical, electrocardiographic, and biochemical data for immediate risk stratification in acute coronary syndromes
    S Savonitto
    Dipartment of Cardiology Angelo De Gasperis, Niguarda Ca Granda Hospital, Milan, Italy
    Ann Noninvasive Electrocardiol 6:64-77. 2001
    ..However, how to best combine electrocardiographic and biochemical data for immediate risk stratification remains to be further elucidated...
  17. ncbi Prothrombotic genetic markers
    M L Rossi
    A De Gasperis Cardiology Department, Hospital Niguarda Ca Granda, Milan, Italy
    Ital Heart J 2:495-8. 2001
    ..In the present editorial, a comment on the studies already available is provided and the possible limitations of the present approach are analyzed...
  18. ncbi Percutaneous coronary revascularisation in women
    M L Rossi
    Dipartimento Cardiologico A. De Gasperis, , Milan, Italy
    Thromb Res 103:S105-11. 2001
    ..Recent clinical trial have provided new insights into this problem. The influence on gender differences for the decision to undertake coronary angiography and percutaneous transluminal coronary angioplasty will be discussed...
  19. ncbi Selection of drug therapy in stable angina pectoris
    S Savonitto
    Second Division of Cardiology, Ospedale Niguarda Ca Granda, Milan, Italy
    Cardiovasc Drugs Ther 12:197-210. 1998
    ....
  20. ncbi Long-term mortality in patients unsuitable for surgical revascularization undergoing elective left main coronary artery angioplasty
    L Vignali
    Division of Cardiology, University Hospital of Parma, Parma, Italy
    Minerva Cardioangiol 56:1-11. 2008
    ..Secondary endpoints were to analyse long-term mortality in various categories (patients<75 years vs patients<75 years, males vs females, drug eluting stents [DES] vs bare metal stents [BMS])...
  21. ncbi Genetic predisposition to atorvastatin-induced myopathy: a case report
    M Francesca Notarangelo
    Division of Cardiology, Azienda Ospedaliero Universitaria of Parma, Parma, Italy
    J Clin Pharm Ther 37:604-6. 2012
    ..Our objective is to report on two cases of statin-induced myopathy occurring in a family with two patients who are carriers of the loss of function SLCO1B1 genetic variant and to briefly review the related literature...
  22. ncbi Different quantitative apoptotic traits in coronary atherosclerotic plaques from patients with stable angina pectoris and acute coronary syndromes
    Marco L Rossi
    Division of Cardiology, Istituto Clinico Humanitas, Milan, Italy
    Circulation 110:1767-73. 2004
    ..We tested the hypothesis that apoptosis is quantitatively increased in unstable atherosclerotic plaques...
  23. ncbi N-terminal pro-brain natriuretic peptide on admission has prognostic value across the whole spectrum of acute coronary syndromes
    Marcello Galvani
    Ospedale G B Morgagni and Fondazione Sacco, Forli, Italy
    Circulation 110:128-34. 2004
    ..We measured N-terminal pro-brain natriuretic peptide (NT-proBNP) on admission in patients with ACS and ECG evidence of myocardial ischemia...
  24. ncbi Impact of the elevation of biochemical markers of myocardial damage on long-term mortality after percutaneous coronary intervention: results of the CK-MB and PCI study
    Claudio Cavallini
    Ospedale Ca Foncello, Divisione di Cardiologia, Piazza Ospedale 1, 31100 Treviso, Italy
    Eur Heart J 26:1494-8. 2005
    ..In this multicentre prospective cohort study, we evaluated the influence of post-procedural elevations of CK-MB and troponin I (cTnI) on long-term mortality...
  25. ncbi Tirofiban in acute coronary syndromes
    Alberto Menozzi
    Division of Cardiology, Maggiore Hospital, University of Parma, Parma, Italy
    Expert Rev Cardiovasc Ther 3:193-206. 2005
    ..In particular, the role of early, upstream tirofiban coupled with early aggressive revascularization in the management of high-risk non-ST-segment elevation acute coronary syndromes is emphasized...
  26. ncbi [Pathogenesis of acute coronary syndromes: the activated plaque]
    Giorgia Paoli
    UO di Cardiologia, Ospedale Maggiore, Parma
    Ital Heart J 6:5S-11S. 2005
    ....
  27. ncbi [Multivessel percutaneous coronary interventions. When incomplete revascularization may represent a therapeutic option]
    Fabrizio Ugo
    UO Cardiologia, Dipartimento del Cuore, Azienda Ospedaliero Universitaria, Parma
    G Ital Cardiol (Rome) 7:36S-46S. 2006
    ....
  28. ncbi [Low-molecular-weight heparins in acute coronary syndrome: acquired results and new perspectives]
    Fabrizio Ugo
    U O di Cardiologia, Dipartimento del Cuore, Azienda Ospedaliero Universitaria Ospedale Maggiore, Parma
    G Ital Cardiol (Rome) 7:771-9. 2006
    ....
  29. ncbi Percutaneous coronary intervention in patients receiving enoxaparin or unfractionated heparin after fibrinolytic therapy for ST-segment elevation myocardial infarction in the ExTRACT-TIMI 25 trial
    C Michael Gibson
    Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Am Coll Cardiol 49:2238-46. 2007
    ....
  30. ncbi Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes
    Jean Pierre Bassand
    Eur Heart J 28:1598-660. 2007
  31. ncbi Prasugrel versus clopidogrel in patients with acute coronary syndromes
    Stephen D Wiviott
    Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 357:2001-15. 2007
    ..Dual-antiplatelet therapy with aspirin and a thienopyridine is a cornerstone of treatment to prevent thrombotic complications of acute coronary syndromes and percutaneous coronary intervention...
  32. doi Impact of acute renal failure following percutaneous coronary intervention on long-term mortality
    Alberto Roghi
    De Gasperis Department of Cardiology, Niguarda Ca Granda Hospital, Milan, Italy
    J Cardiovasc Med (Hagerstown) 9:375-81. 2008
    ..Whether this event should be considered as a marker of disease severity or an independent contributor to mortality is still unclear...
  33. ncbi In-hospital and one-year outcomes of patients with high-risk acute myocardial infarction treated with thrombolysis or primary coronary angioplasty
    Giuseppe Steffenino
    Department of Cardiology, S Croce e Carle Hospital, Cuneo, Italy
    Ital Heart J 5:136-45. 2004
    ..The aim of this study was to observe the outcomes of high-risk patients with acute myocardial infarction treated with primary angioplasty and intravenous thrombolysis in a community setting...
  34. ncbi Coagulation activation and long-term outcome in acute coronary syndromes
    Diego Ardissino
    Division of Cardiology, Ospedale Niguarda Ca Grande, Milan
    Blood 102:2731-5. 2003
    ..25-2.28; RR, 1.35 and 95% CI, 1.11-1.86, respectively). After an episode of acute coronary syndrome, both high and low levels of thrombin generation are predictors of an increased risk of an unfavorable outcome...
  35. ncbi One-year follow-up of the ASSENT-2 trial: a double-blind, randomized comparison of single-bolus tenecteplase and front-loaded alteplase in 16,949 patients with ST-elevation acute myocardial infarction
    Peter Sinnaeve
    Department of Cardiology, University of Leuven, Leuven, Belgium
    Am Heart J 146:27-32. 2003
    ..The aim of this study is to assess mortality rates after 1-year follow-up...
  36. ncbi Safety and efficacy of enoxaparin vs unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes who receive tirofiban and aspirin: a randomized controlled trial
    Michael A Blazing
    Duke Clinical Research Institute, Durham, NC, USA
    JAMA 292:55-64. 2004
    ..It is not clear if combining enoxaparin with glycoprotein IIb/IIIa inhibitors is as safe or as effective as the current standard combination of unfractionated heparin with glycoprotein IIb/IIIa inhibitors...
  37. ncbi Association between admission white blood cell count and one-year mortality in patients with acute coronary syndromes
    Michael H Yen
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Med 115:318-21. 2003
  38. ncbi Mortality at 1 year with combination platelet glycoprotein IIb/IIIa inhibition and reduced-dose fibrinolytic therapy vs conventional fibrinolytic therapy for acute myocardial infarction: GUSTO V randomized trial
    A Michael Lincoff
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    JAMA 288:2130-5. 2002
    ..Rates of nonfatal ischemic complications were significantly diminished...
  39. ncbi [Acute coronary syndromes with ST-segment elevation: primary angioplasty]
    Giorgia Paoli
    Dipartimento di Cardiologia, Ospedale Maggiore, Parma
    Ital Heart J 4:16S-20S. 2003
  40. ncbi Mortality at 1 year for the direct comparison of tirofiban and abciximab during percutaneous coronary revascularization: do tirofiban and ReoPro give similar efficacy outcomes at trial 1-year follow-up
    Debabrata Mukherjee
    Division of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY 40536 0200, USA
    Eur Heart J 26:2524-8. 2005
    ..We report here the 1-year mortality of the study population...
  41. ncbi Outcomes at 6 months for the direct comparison of tirofiban and abciximab during percutaneous coronary revascularisation with stent placement: the TARGET follow-up study
    David J Moliterno
    Department of Cardiovascular Medicine and C5 Cleveland Clinic Cardiovascular Coordinating Center, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Lancet 360:355-60. 2002
    ....
  42. ncbi Comparison of outcomes of patients with myocardial infarction when living alone versus those not living alone
    J Conor O'Shea
    Duke Clinical Research Institute, Durham, North Carolina, USA
    Am J Cardiol 90:1374-7. 2002
  43. ncbi Management of acute myocardial infarction in patients presenting with ST-segment elevation. The Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology
    Frans Van de Werf
    Cardiology, Gasthuisberg University Hospital, Leuven, Belgium
    Eur Heart J 24:28-66. 2003
  44. ncbi Effectiveness of adjunctive stent implantation following directional coronary atherectomy for treatment of left anterior descending ostial stenosis
    Ezio Bramucci
    Department of Cardiology, I R C C S Policlinico San Matteo, Piazzale Golgi 2, 27100 Pavia, Italy
    Am J Cardiol 90:1074-8. 2002
    ..These results indicate that the combined approach of DCA and stent implantation is feasible and safe in patients with LAD ostial lesions, has a high success rate, a low incidence of restenosis, and a good long-term outcome...
  45. ncbi The prognostic value of creatine kinase elevations extends across the whole spectrum of acute coronary syndromes
    Stefano Savonitto
    Department of Cardiology, Niguarda Hospital, Milan, Italy
    J Am Coll Cardiol 39:22-9. 2002
    ..The study investigated the relationship among creatine kinase (CK) elevations, clinical characteristics and cardiac events across the whole spectrum of acute coronary syndromes (ACS)...
  46. ncbi Plasma and urinary free 3-nitrotyrosine following cardiac angiography procedures with non-ionic radiocontrast media
    Enrico Fiaccadori
    Dipartimento di Clinica Medica, Nefrologia e Scienze della Prevenzione, Universita degli Studi di Parma, Via Gramsci 14, 43100 Parma, Italy
    Nephrol Dial Transplant 19:865-9. 2004
    ..However, no study has been published showing that RCM administration elicits oxidative stress in humans...
  47. ncbi Risk of myocardial infarction and polymorphisms in candidate genes
    Pier M Mannucci
    N Engl J Med 348:1176-7; author reply 1176-7. 2003
  48. ncbi [Guidelines on the management of stable angina pectoris; the experts of the European Society of Cardiology on the management of stable angina pectoris]
    Kim Fox
    Department of Cardiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK
    Kardiol Pol 64:823-80. 2006
  49. ncbi Expression of endothelial protein C receptor and thrombomodulin in human coronary atherosclerotic plaques
    Piera Angelica Merlini
    Division of Cardiology, Niguarda Ca Granda Hospital, Milan, Italy
    Ital Heart J 5:42-7. 2004
    ....
  50. ncbi Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology
    Kim Fox
    Department of Cardiology, Royal Brompton Hospital, London, UK
    Eur Heart J 27:1341-81. 2006
  51. ncbi Angiotensin-converting enzyme insertion/deletion polymorphism and risk of restenosis after directional coronary atherectomy followed by stent implantation
    Umberto Canosi
    Divisione di Cardiologia IRCCS Policlinico San Matteo, Piazza Golgi 2, 27100 Pavia, Italy
    Thromb Haemost 91:795-800. 2004
    ..Our results indicate that ACE I/D polymorphism does not influence the risk of developing angiographic restenosis in patients undergoing DCA followed by stent implantation...
  52. ncbi Images in cardiovascular medicine. Magnetic resonance imaging of impending left ventricular rupture after acute myocardial infarction
    Antonello Zoni
    Division of Cardiology, University Hospital, Parma, Italy
    Circulation 108:498-9. 2003
  53. ncbi Sirolimus-eluting vs uncoated stents for prevention of restenosis in small coronary arteries: a randomized trial
    Diego Ardissino
    Division of Cardiology, Ospedale Maggiore, University of Parma, Italy
    JAMA 292:2727-34. 2004
    ..Sirolimus-eluting stents reduce restenosis in simple and previously untreated lesions of large coronary arteries, but their outcomes in small vessels have not been adequately investigated...
  54. ncbi [Expert Consensus document on angiotensin converting enzyme inhibitors in cardiovascular disease]
    Jose Lopez-Sendon
    Rev Esp Cardiol 57:1213-32. 2004
  55. ncbi Effectiveness of treatment of in-stent restenosis with an 8-French compatible atherectomy catheter
    Flavio Airoldi
    EMO Centro Cuore, Columbus Clinic, Via Buonarroti 48 20145 Milan, Italy
    Am J Cardiol 92:725-8. 2003
    ..6% of patients. The secondary end point regarding the incidence of angiographic restenosis at 6 months showed a high restenosis rate (65%)...
  56. ncbi Vagaries of genetic association studies in myocardial infarction
    Pier M Mannucci
    Blood 102:1558-9; author reply 1559-60. 2003
  57. ncbi Effect of sirolimus-eluting stent in diabetic patients with small coronary arteries (a SES-SMART substudy)
    Paolo Ortolani
    Institute of Cardiology, Policlinico S Orsola, University of Bologna, Bologna, Italy
    Am J Cardiol 96:1393-8. 2005
    ..In conclusion, in diabetics with small coronary arteries, SES implantation significantly reduces the incidence of the 8-month angiographic restenosis rate compared with BMSs...
  58. pmc The thrombospondin-1 N700S polymorphism is associated with early myocardial infarction without altering von Willebrand factor multimer size
    Jeffrey I Zwicker
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Blood 108:1280-3. 2006
    ....
  59. ncbi Usefulness of 64-slice multislice computed tomography coronary angiography to assess in-stent restenosis
    Filippo Cademartiri
    Department of Radiology and Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Am Coll Cardiol 49:2204-10. 2007
    ..This study sought to evaluate the diagnostic accuracy of 64-slice multislice computed tomography (MSCT) coronary angiography in the follow-up of patients with previous coronary stent implantation...