Francesco Orio

Summary

Country: Italy

Publications

  1. ncbi request reprint Effects of physical exercise on the female reproductive system
    F Orio
    Department of Endocrinology Parthenope University of Naples, Naples, Italy
    Minerva Endocrinol 38:305-19. 2013
  2. pmc Liver-spleen axis, insulin-like growth factor-(IGF)-I axis and fat mass in overweight/obese females
    Silvia Savastano
    Department of Molecular and Clinical Endocrinology and Oncology, Division of Endocrinology, Federico II University Medical School, Via S, Pansini 5 80131 Naples Italy
    J Transl Med 9:136. 2011
  3. pmc Changes in androgens and insulin sensitivity indexes throughout pregnancy in women with polycystic ovary syndrome (PCOS): relationships with adverse outcomes
    Angela Falbo
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    J Ovarian Res 3:23. 2010
  4. pmc Serum and follicular anti-Mullerian hormone levels in women with polycystic ovary syndrome (PCOS) under metformin
    Angela Falbo
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    J Ovarian Res 3:16. 2010
  5. pmc Does metformin affect ovarian morphology in patients with polycystic ovary syndrome? A retrospective cross-sectional preliminary analysis
    Angela Falbo
    Departments of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    J Ovarian Res 2:5. 2009
  6. ncbi request reprint Adrenal adenoma and normal androgen levels in a young woman with polycystic ovaries: a case of idiopathic hirsutism?
    F Orio
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University, Naples, Italy
    J Endocrinol Invest 27:61-6. 2004
  7. ncbi request reprint The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective case-control study
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, Naples, Italy
    J Clin Endocrinol Metab 89:3696-701. 2004
  8. ncbi request reprint Cardiovascular risk in women with polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University of Naples Federico II, Naples, Italy
    Fertil Steril 86:S20-1. 2006
  9. ncbi request reprint Early impairment of endothelial structure and function in young normal-weight women with polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II of Naples, Via S Pansini 5, 80131 Naples, Italy
    J Clin Endocrinol Metab 89:4588-93. 2004
  10. ncbi request reprint Cardiopulmonary impairment in young women with polycystic ovary syndrome
    Francesco Orio
    Department of Molecular, Clinical Endocrinology, and Oncology, University Federico II of Naples, Via S Pansini 5, 80131 Naples, Italy
    J Clin Endocrinol Metab 91:2967-71. 2006

Collaborators

Detail Information

Publications87

  1. ncbi request reprint Effects of physical exercise on the female reproductive system
    F Orio
    Department of Endocrinology Parthenope University of Naples, Naples, Italy
    Minerva Endocrinol 38:305-19. 2013
    ..g. breast cancer). When the excess in physical activity leads up to the female athlete triad, it is imperative to treat each component of the triad by employing both pharmacological and non pharmacological treatments. ..
  2. pmc Liver-spleen axis, insulin-like growth factor-(IGF)-I axis and fat mass in overweight/obese females
    Silvia Savastano
    Department of Molecular and Clinical Endocrinology and Oncology, Division of Endocrinology, Federico II University Medical School, Via S, Pansini 5 80131 Naples Italy
    J Transl Med 9:136. 2011
    ..We tested the hypothesis that FM, or spleen volume and C-reactive protein (CRP)--all indexes of chronic inflammation--could affect the IGF-I axis status in overweight/obese, independently of HS...
  3. pmc Changes in androgens and insulin sensitivity indexes throughout pregnancy in women with polycystic ovary syndrome (PCOS): relationships with adverse outcomes
    Angela Falbo
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    J Ovarian Res 3:23. 2010
    ....
  4. pmc Serum and follicular anti-Mullerian hormone levels in women with polycystic ovary syndrome (PCOS) under metformin
    Angela Falbo
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    J Ovarian Res 3:16. 2010
    ..The aim of the present study was to evaluate in patients with polycystic ovary syndrome (PCOS) whether metformin administration affects serum and follicular AMH levels, and whether this is related to ovarian response to the treatment...
  5. pmc Does metformin affect ovarian morphology in patients with polycystic ovary syndrome? A retrospective cross-sectional preliminary analysis
    Angela Falbo
    Departments of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    J Ovarian Res 2:5. 2009
    ..The aim of this study was to evaluate ovarian morphology in patients affected by PCOS with different ovulatory responses to metformin...
  6. ncbi request reprint Adrenal adenoma and normal androgen levels in a young woman with polycystic ovaries: a case of idiopathic hirsutism?
    F Orio
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University, Naples, Italy
    J Endocrinol Invest 27:61-6. 2004
    ..This case report underlines the need of cautious interpretation of imaging results and clinical signs of severe hirsutism, reminding one that the true cause of a medical problem may not be the most evident...
  7. ncbi request reprint The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective case-control study
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, Naples, Italy
    J Clin Endocrinol Metab 89:3696-701. 2004
    ..In conclusion, our data show the detrimental effect of PCOS on the cardiovascular system even in young women asymptomatic for cardiac disease...
  8. ncbi request reprint Cardiovascular risk in women with polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University of Naples Federico II, Naples, Italy
    Fertil Steril 86:S20-1. 2006
    ..Polycystic ovary syndrome (PCOS) is not only a reproductive problem but a complex, endocrine, multifaceted disease with several health complications. Cardiovascular abnormalities represent important long-term sequelae of PCOS...
  9. ncbi request reprint Early impairment of endothelial structure and function in young normal-weight women with polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II of Naples, Via S Pansini 5, 80131 Naples, Italy
    J Clin Endocrinol Metab 89:4588-93. 2004
    ..0.5 +/- 0.2 pmol/liter for PCOS patients and controls, respectively).In conclusion, our data show that young, normal-weight, nondyslipidemic, nonhypertensive women with PCOS have an early impairment of endothelial structure and function...
  10. ncbi request reprint Cardiopulmonary impairment in young women with polycystic ovary syndrome
    Francesco Orio
    Department of Molecular, Clinical Endocrinology, and Oncology, University Federico II of Naples, Via S Pansini 5, 80131 Naples, Italy
    J Clin Endocrinol Metab 91:2967-71. 2006
    ..At the moment, no evaluation of cardiopulmonary functional capacity in young patients with PCOS has been performed...
  11. ncbi request reprint Lack of an association between peroxisome proliferator-activated receptor-gamma gene Pro12Ala polymorphism and adiponectin levels in the polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, Naples, Italy
    J Clin Endocrinol Metab 89:5110-5. 2004
    ..In conclusion, our results confirm that adiponectin concentrations are similar in PCOS and controls and demonstrate no effect of the PPAR-gamma gene Pro12Ala polymorphism on serum adiponectin levels...
  12. ncbi request reprint The increase of leukocytes as a new putative marker of low-grade chronic inflammation and early cardiovascular risk in polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology, University Federico II, Naples, Italy
    J Clin Endocrinol Metab 90:2-5. 2005
    ..In conclusion, our data demonstrate that PCOS women have an increased WBC count that correlates with homeostasis model assessment values...
  13. ncbi request reprint Is plasminogen activator inhibitor-1 a cardiovascular risk factor in young women with polycystic ovary syndrome?
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, Italy
    Reprod Biomed Online 9:505-10. 2004
    ..In conclusion, women with PCOS have significantly elevated PAI-1 activity independent of obesity, and it is speculated that elevated PAI-1 activity may be a factor in the increased cardiovascular morbidity seen in PCOS...
  14. ncbi request reprint Metabolic and cardiovascular consequences of polycystic ovary syndrome
    F Orio
    Department of Endocrinology, Parthenope University, Naples, Italy
    Minerva Ginecol 60:39-51. 2008
    ....
  15. ncbi request reprint Metformin administration improves leukocyte count in women with polycystic ovary syndrome: a 6-month prospective study
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, Via S Pansini 5, 80131 Naples, Italy
    Eur J Endocrinol 157:69-73. 2007
    ..Low-grade chronic inflammation is a related complication recently observed in PCOS. Increased white blood cell (WBC) count was previously reported in PCOS women...
  16. ncbi request reprint Metabolic and cardiopulmonary effects of detraining after a structured exercise training programme in young PCOS women
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, Naples, Italy
    Clin Endocrinol (Oxf) 68:976-81. 2008
    ..The aim of the present study was to determine if the favourable cardiopulmonary and metabolic benefits induced by exercise training (ET) programme are maintained after its cessation...
  17. ncbi request reprint Improvement in endothelial structure and function after metformin treatment in young normal-weight women with polycystic ovary syndrome: results of a 6-month study
    Francesco Orio
    Department of Molecular, Clinical Endocrinology and Oncology, University Federico II, Via S Pansini 5, 80131 Naples, Italy
    J Clin Endocrinol Metab 90:6072-6. 2005
    ..Recent data indicate that women affected by the polycystic ovary syndrome (PCOS) are at greater risk for cardiovascular disease and that metformin may improve the metabolic alterations in these patients...
  18. ncbi request reprint Lack of electrocardiographic changes in women with polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II of Naples, Naples, Italy
    Clin Endocrinol (Oxf) 67:46-50. 2007
    ..The aim of the present study was to investigate the potential alterations in electrocardiographic (ECG) pattern in patients with polycystic ovary syndrome (PCOS)...
  19. ncbi request reprint Cardiovascular complications of obesity in adolescents
    F Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, 80131 Naples, Italy
    J Endocrinol Invest 30:70-80. 2007
    ..The foremost physical consequence of obesity is atherosclerotic CVD, and an intriguing example of obesity-related cardiovascular complications affecting young women is the polycystic ovary syndrome (PCOS)...
  20. ncbi request reprint Genetic analysis of the follicle stimulating hormone receptor gene in women with polycystic ovary syndrome
    F Orio
    Dipartimento di Endocrinologia ed Oncologia Molecolare e Clinica, Università Federico II Napoli Via S Pansini 5, 80131 Napoli, Italia
    J Endocrinol Invest 29:975-82. 2006
    ..In conclusion, the present study demonstrates that mutations of the FSHr gene are rare in Italian women. The only mutation that we found does not appear to have any pathophysiological significance in PCOS...
  21. ncbi request reprint [Polycystic ovary syndrome: an example of obesity-related cardiovascular complication affecting young women]
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II of Naples, Via S Pansini 5, 80131 Naples, Italy
    Monaldi Arch Chest Dis 66:48-53. 2006
    ..All these features, probably linked to insulin-resistance, are often present in obese PCOS patients. Cardiovascular abnormalities represent important long-term sequelae of PCOS that need further investigations...
  22. ncbi request reprint Beneficial effects of a three-month structured exercise training program on cardiopulmonary functional capacity in young women with polycystic ovary syndrome
    Carlo Vigorito
    Department of Clinical Medicine, University Federico II of Naples, Italy
    J Clin Endocrinol Metab 92:1379-84. 2007
    ..An impaired cardiopulmonary functional capacity was previously demonstrated in PCOS women. No data regarding the effects of a structured exercise training (ET) program on cardiopulmonary functional capacity in PCOS women are available...
  23. ncbi request reprint Visceral fat is associated with cardiovascular risk in women with polycystic ovary syndrome
    Teresa Cascella
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, Naples 80131, Italy
    Hum Reprod 23:153-9. 2008
    ..The aim of this study was to evaluate the relationship between visceral fat (VF) and early markers of CVD in PCOS women...
  24. doi request reprint Relationship between growth hormone/insulin-like growth factor-1 axis integrity and voluntary weight loss after gastric banding surgery for severe obesity
    Silvia Savastano
    Division of Endocrinology, Department of Molecular and Clinical Endocrinology and Oncology, University of Naples Federico II, Via S Pansini 5, 80131 Naples, Italy
    Obes Surg 20:211-20. 2010
    ....
  25. ncbi request reprint Abnormal heart rate recovery after maximal cardiopulmonary exercise stress testing in young overweight women with polycystic ovary syndrome
    Francesco Giallauria
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Cardiac Rehabilitation Unit, University Federico II of Naples, Naples, Italy
    Clin Endocrinol (Oxf) 68:88-93. 2008
    ..Abnormal HRR is a measure of autonomic dysfunction associated with an increased mortality. This study was performed to evaluate the HRR in polycystic ovary syndrome (PCOS)...
  26. ncbi request reprint Overexpression of the phosphoprotein enriched in diabetes gene product (Ped/pea-15) in women with polycystic ovary syndrome
    Silvia Savastano
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, Naples, Italy
    Clin Endocrinol (Oxf) 67:557-62. 2007
    ..To evaluate Ped/pea-15 (phosphoprotein enriched in diabetes) expression in polycystic ovary syndrome (PCOS) women...
  27. ncbi request reprint Homocysteine levels and C677T polymorphism of methylenetetrahydrofolate reductase in women with polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University of Naples Federico II, 80131 Naples, Italy
    J Clin Endocrinol Metab 88:673-9. 2003
    ..5 +/- 3.9 vs. 22.0 +/- 7.8 micromol/liter +/- SD). In conclusion, our data show that in PCOS women, the serum Hcy levels are normal, and the C677T polymorphism of MTHFR does not influence the Hcy levels like in controls...
  28. ncbi request reprint Inflammatory markers and visceral fat are inversely associated with maximal oxygen consumption in women with polycystic ovary syndrome (PCOS)
    Francesco Giallauria
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Cardiac Rehabilitation Unit, Federico II University of Naples, Naples, Italy
    Clin Endocrinol (Oxf) 70:394-400. 2009
    ....
  29. ncbi request reprint A randomized controlled trial evaluating metformin pre-treatment and co-administration in non-obese insulin-resistant women with polycystic ovary syndrome treated with controlled ovarian stimulation plus timed intercourse or intrauterine insemination
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Naples, Italy
    Hum Reprod 20:2879-86. 2005
    ....
  30. doi request reprint Cardiovascular risk in women with polycystic ovary syndrome
    Francesco Giallauria
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Naples, Italy
    J Cardiovasc Med (Hagerstown) 9:987-92. 2008
    ....
  31. ncbi request reprint Growth hormone treatment prevents loss of lean mass after bariatric surgery in morbidly obese patients: results of a pilot, open, prospective, randomized, controlled study
    Silvia Savastano
    Department of Molecular and Clinical Endocrinology and Oncology, Division of Endocrinology, University Federico II of Naples, 80131 Naples, Italy
    J Clin Endocrinol Metab 94:817-26. 2009
    ..The loss of lean body mass (LBM) negatively influences the outcome in bariatric surgery. Impaired GH secretion is frequent in obese patients...
  32. ncbi request reprint Uterine effects of metformin administration in anovulatory women with polycystic ovary syndrome
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, University Federico II of Naples, Italy
    Hum Reprod 21:457-65. 2006
    ..CONCLUSIONS: Metformin improves all surrogate markers of endometrial receptivity in PCOS patients, without difference between patients who had favourable or unfavourable reproductive outcome...
  33. ncbi request reprint Serum aldosterone concentration and cardiovascular risk in women with polycystic ovarian syndrome
    Teresa Cascella
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II of Naples, Via S Pansini 5, 80131 Naples, Italy
    J Clin Endocrinol Metab 91:4395-400. 2006
    ..Polycystic ovary syndrome (PCOS) is associated with early impairment of vascular structure and a low-grade chronic inflammation. Aldosterone is a well-recognized cardiovascular risk (CVR) factor and is related to inflammatory processes...
  34. ncbi request reprint Adiponectin levels in women with polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, 80131 Naples, Italy
    J Clin Endocrinol Metab 88:2619-23. 2003
    ..They further suggest that insulin sensitivity per se probably does not play any pivotal role in the control of adiponectin levels in PCOS women...
  35. ncbi request reprint Exon 6 and 2 peroxisome proliferator-activated receptor-gamma polymorphisms in polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, 80131 Naples, Italy
    J Clin Endocrinol Metab 88:5887-92. 2003
    ....
  36. ncbi request reprint Hypothalamic-pituitary-gonadal axis function after successful kidney transplantation in men and women
    Libuse Tauchmanova
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II of Naples, Cantazaro, Italy
    Hum Reprod 19:867-73. 2004
    ..Renal transplantation (RT) is the most common solid organ transplant procedure. Several studies have reported on gonadal function in male and female RT recipients with controversial results...
  37. doi request reprint GH and IGF-I deficiency are associated with reduced loss of fat mass after laparoscopic-adjustable silicone gastric banding
    Carolina Di Somma
    Department of Molecular and Clinical Endocrinology and Oncology, Division of Endocrinology, University Federico II of Naples, Naples, Italy
    Clin Endocrinol (Oxf) 69:393-9. 2008
    ..It is still unclear if changes in the GH/IGF-I axis after laparoscopic-adjustable silicone gastric banding (LASGB) are associated with changes of body composition...
  38. ncbi request reprint Circulating ghrelin concentrations in the polycystic ovary syndrome
    Francesco Orio
    Department of Molecular and Clinical Endocrinology, University Federico II, Naples, Italy
    J Clin Endocrinol Metab 88:942-5. 2003
    ..There is no relationship between circulating ghrelin and the abnormal hormonal pattern of the PCOS syndrome...
  39. doi request reprint Androgens in polycystic ovary syndrome: the role of exercise and diet
    Francesco Giallauria
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University of Naples Federico II, Naples, Italy
    Semin Reprod Med 27:306-15. 2009
    ....
  40. ncbi request reprint Prospective parallel randomized, double-blind, double-dummy controlled clinical trial comparing clomiphene citrate and metformin as the first-line treatment for ovulation induction in nonobese anovulatory women with polycystic ovary syndrome
    Stefano Palomba
    Department of Gynecology and Obstetrics, University Magna Graecia of Catanzar, Via Nicolardi 188, 80131 Naples, Italy
    J Clin Endocrinol Metab 90:4068-74. 2005
    ..Although metformin has been shown to be effective in the treatment of anovulation in women with polycystic ovary syndrome (PCOS), clomiphene citrate (CC) is still considered to be the first-line drug to induce ovulation in these patients...
  41. ncbi request reprint Endocrine disorders during the first year after autologous stem-cell transplant
    Libuse Tauchmanova
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, Italy
    Am J Med 118:664-70. 2005
    ..Frequent endocrine disorders have been reported after allogeneic stem-cell transplant, but data on adult survivors of autologous transplants are still scarce...
  42. ncbi request reprint Insulin-like growth factor-1 deficiency determines increased intima-media thickness at common carotid arteries in adult patients with growth hormone deficiency
    Annamaria Colao
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, Italy
    Clin Endocrinol (Oxf) 61:360-6. 2004
    ..To investigate the role of IGF-1 on intima-media thickness (IMT) at common carotid arteries by Doppler ultrasonography...
  43. ncbi request reprint Favourable effects of exercise-based Cardiac Rehabilitation after acute myocardial infarction on left atrial remodeling
    Francesco Giallauria
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Cardiac Rehabilitation Unit, University of Naples Federico II, Naples, Italy
    Int J Cardiol 136:300-6. 2009
    ..This study investigated the effects of CR on LA remodeling in postinfarction patients with moderate left ventricular (LV) dysfunction...
  44. ncbi request reprint Gonadal status in reproductive age women after haematopoietic stem cell transplantation for haematological malignancies
    Libuse Tauchmanova
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, Via S Pansini 5, 80131 Naples, Italy
    Hum Reprod 18:1410-6. 2003
    ..Ovarian failure is a frequent complication occurring after haematopoietic stem cell transplantion (SCT), which is generally ascribed to radiation treatment and antiblastic alkylating agents...
  45. doi request reprint Bisphenol A in polycystic ovary syndrome and its association with liver-spleen axis
    Giovanni Tarantino
    Department of Clinical and Experimental Medicine, University Federico II of Naples, Naples, Italy
    Clin Endocrinol (Oxf) 78:447-53. 2013
    ..Increased spleen volume, a reliable and stable index of chronic inflammation, was strictly associated with the severity of hepatic steatosis (HS) in obese subjects, determining the so-called liver-spleen axis...
  46. doi request reprint Perifollicular vascularity assessment for selecting the best oocytes for in vitro fertilization programs in older patients
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Naples, Italy
    Fertil Steril 90:1305-9. 2008
    ..Data obtained from 60 infertile patients who were >40 years of age and were unselected for ovarian reserve showed that this approach does not improve any reproductive outcomes in IVF programs...
  47. pmc Relationship between heart rate recovery and inflammatory markers in patients with polycystic ovary syndrome: a cross-sectional study
    Francesco Giallauria
    Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Cardiac Rehabilitation Unit, University of Naples Federico II, Naples, Italy
    J Ovarian Res 2:3. 2009
    ..A subclinical increase of the inflammation markers has been also observed in the PCOS. This study was designed to study the relationships between HRR and inflammatory markers in PCOS women...
  48. pmc Serum 25-Hydroxyvitamin D Levels, phosphoprotein enriched in diabetes gene product (PED/PEA-15) and leptin-to-adiponectin ratio in women with PCOS
    Silvia Savastano
    Department of Molecular and Clinical Endocrinology and Oncology, Division of Endocrinology, University Federico II of Naples, Via S, Pansini 5, Naples, 80131, Italy
    Nutr Metab (Lond) 8:84. 2011
    ..abstract:..
  49. ncbi request reprint The cardiovascular risk of GH-deficient adolescents
    Annamaria Colao
    Department of Molecular and Clinical Endocrinology and Oncology, University Federico II of Naples, 80131 Naples, Italy
    J Clin Endocrinol Metab 87:3650-5. 2002
    ..Because the results on the cardiovascular system and on the lipid profile were suboptimal, it is likely that the GH dose in severe GHD adolescents should be higher...
  50. doi request reprint Left ventricular remodelling in patients with moderate systolic dysfunction after myocardial infarction: favourable effects of exercise training and predictive role of N-terminal pro-brain natriuretic peptide
    Francesco Giallauria
    Cardiac Rehabilitation Unit, Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University of Naples Federico II, Naples, Naples, Italy
    Eur J Cardiovasc Prev Rehabil 15:113-8. 2008
    ....
  51. ncbi request reprint Circulating IGF-I levels are associated with increased biventricular contractility in top-level rowers
    Giovanni Vitale
    Department of Molecular and Clinical Endocrinology and Oncology, University of Naples Federico II, Naples, Italy
    Clin Endocrinol (Oxf) 69:231-6. 2008
    ..The intensive physical activity is often associated with cardiac changes...
  52. ncbi request reprint Six months of treatment with cabergoline restores sexual potency in hyperprolactinemic males: an open longitudinal study monitoring nocturnal penile tumescence
    Michele De Rosa
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, 80131 Naples, Italy
    J Clin Endocrinol Metab 89:621-5. 2004
    ..7% of controls. Six months of treatment with cabergoline normalized testosterone levels in most cases, thus restoring and maintaining during treatment the capability of normal sexual activity in hyperprolactinemic males...
  53. ncbi request reprint High prevalence of endocrine dysfunction in long-term survivors after allogeneic bone marrow transplantation for hematologic diseases
    Libuse Tauchmanova
    Department of Molecular and Clinical Endocrinology and Oncology, Federico II University, Naples, Italy
    Cancer 95:1076-84. 2002
    ..The extent to which chemotherapy and immune system derangement affect endocrine function in allo-BMT recipients is still unclear...
  54. ncbi request reprint Preliminary data on effects of metformin on PED/PEA-15 cellular levels in obese women with polycystic ovary syndrome
    S Savastano
    Division of Endocrinology, Department of Molecular and Clinical Endocrinology and Oncology, University Federico II of Naples, Via S Pansini 5, 80131 Naples, Italy
    J Endocrinol Invest 33:446-50. 2010
    ..The cellular abundance of the phosphoprotein enriched in diabetes (PED/PEA-15), a 15 kDa protein related to insulin resistance (IR), is increased in women with polycystic ovary syndrome (PCOS)...
  55. ncbi request reprint Report on the Third Annual Meeting of the Androgen Excess Society, San Diego, California, June 3, 2005
    Francesco Orio
    University Federico II, Naples, Italy
    Fertil Steril 86:1318-20. 2006
    ..The experience of the 21-OH-deficient Nonclassical Adrenal Hyperplasia (NCAH) Multicenter Study Group was also discussed, along with a keynote presentation on the molecular aspects of 3beta-HSD-deficient NCAH...
  56. ncbi request reprint [Polycystic ovary syndrome and obesity: non pharmacological approaches]
    F Orio
    Dipartimento di Endocrinologia, Facoltà di Scienze Motorie, Università degli Studi di Napoli Parthenope, Naples, Italy
    Minerva Ginecol 59:63-73. 2007
    ..Anyway other studies are necessary to justify a similar assertion in women with PCOS. At the same way, the optimum regimen of physical exercise for PCOS women is still to be demonstrated...
  57. ncbi request reprint GH release after GHRH plus arginine administration in obese and overweight women with polycystic ovary syndrome
    F Orio
    Department of Molecular and Clinical Endocrinology, University of Naples Federico II, Naples, Italy
    J Endocrinol Invest 26:117-22. 2003
    ..In conclusion, in PCOS women there is a BMI-independent alteration of the GH levels. Further investigations will be necessary to establish the real cause of these data...
  58. ncbi request reprint Screening a coastal population in Southern Italy: iodine deficiency and prevalence of goitre, nutritional aspects and cardiovascular risk factors
    R Valentino
    Istituto di Endocrinologia ed Oncologia Sperimentale G Salvatore, Consiglio Nazionale delle Ricerche, Dipartimento di Biologia e Patologia Cellulare e Molecolare, Naples, Italy
    Nutr Metab Cardiovasc Dis 14:15-9. 2004
    ..To evaluate the prevalence of goitre by means of urinary iodine excretion, palpatory and ultrasonographic thyroid examinations in a heterogeneous population living by the sea...
  59. ncbi request reprint Outlook: metformin use in infertile patients with polycystic ovary syndrome: an evidence-based overview
    Stefano Palomba
    Department of Gynecology and Obstetrics, University Magna Graecia of Catanzaro, Italy
    Reprod Biomed Online 16:327-35. 2008
    ..Co-administration of metformin in PCOS patients treated with gonadotrophin improves the mono-ovulation rate and can prevent ovarian hyperstimulation syndrome in patients treated with gonadotrophins for IVF cycles...
  60. ncbi request reprint Are serum adiponectin levels really reduced in obese women with polycystic ovary syndrome?
    Francesco Orio
    Hum Reprod 19:215; author reply 215-6. 2004
  61. ncbi request reprint Effects of metformin and clomiphene citrate on ovarian vascularity in patients with polycystic ovary syndrome
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia, Catanzaro, Italy
    Fertil Steril 86:1694-701. 2006
    ..To evaluate the effects of metformin and of clomiphene citrate (CC) on the ovarian blood perfusion and on perifollicular and peri-corpus luteum (CL) vascularity in anovulatory women with polycystic ovary syndrome (PCOS)...
  62. ncbi request reprint Ovulation induction in women with polycystic ovary syndrome
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Fertil Steril 86:S26-7. 2006
    ..Metformin alone or combined with CC is a valid second step approach, whereas the laparoscopic ovarian diathermy can be useful only in selected cases...
  63. ncbi request reprint Metformin hydrochloride and recurrent miscarriage in a woman with polycystic ovary syndrome
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Italy
    Fertil Steril 85:1511.e3-5. 2006
    ..To report the effect of metformin treatment on a patient with recurrent miscarriage (RM) and polycystic ovary syndrome (PCOS)...
  64. ncbi request reprint Plasminogen activator inhibitor 1 and miscarriage after metformin treatment and laparoscopic ovarian drilling in patients with polycystic ovary syndrome
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Fertil Steril 84:761-5. 2005
    ..The lack of a decrease in PAI-1 activity is related to a high risk for miscarriage...
  65. ncbi request reprint Insulin resistance in postmenopausal women with metabolic syndrome and the measurements of adiponectin, leptin, resistin, and ghrelin
    Micheline C Chu
    Department of Obstetrics and Gynecology, Columbia University, New York, NY, USA
    Am J Obstet Gynecol 194:100-4. 2006
    ....
  66. ncbi request reprint Impaired cardiopulmonary parameters in young women with polycystic ovary syndrome
    Francesco Orio
    Clin Endocrinol (Oxf) 66:152-3. 2007
  67. ncbi request reprint [Cardiovascular complications of obesity]
    Teresa Cascella
    Dipartimento di Endocrinologia ed Oncologia Molecolare and Clinica, Universita degli Studi di Napoli Federico II, Via S Pansini, 5 80131 Napoli
    Monaldi Arch Chest Dis 66:270-4. 2006
    ..The foremost physical consequence of obesity is atherosclerotic cardiovascular disease and polycystic ovary syndrome represents an intriguing example of obesity-related cardiovascular complications affecting young women...
  68. ncbi request reprint Abdominal fat quantity and distribution in women with polycystic ovary syndrome and extent of its relation to insulin resistance
    Enrico Carmina
    Department of Clinical Medicine and Emerging Diseases, University of Palermo, Via delle Croci 47, 90139 Palermo, Italy
    J Clin Endocrinol Metab 92:2500-5. 2007
    ..Because many patients with polycystic ovary syndrome (PCOS) present abdominal obesity, it may be the cause of insulin resistance in this disorder...
  69. ncbi request reprint Insulin sensitivity after metformin suspension in normal-weight women with polycystic ovary syndrome
    Stefano Palomba
    Department of Gynecology and Obstetrics, University Magna Graecia of Catanzaro, Via Pio X, 88100 Catanzaro, Italy
    J Clin Endocrinol Metab 92:3128-35. 2007
    ..To date, the metabolic effects of the long-term metformin administration in anovulatory patients with polycystic ovary syndrome (PCOS) are known, whereas few data are available on the effects of its suspension...
  70. ncbi request reprint Metformin administration and laparoscopic ovarian drilling improve ovarian response to clomiphene citrate (CC) in oligo-anovulatory CC-resistant women with polycystic ovary syndrome
    Stefano Palomba
    Department of Obstetrics and Gynaecology, University Magna Graecia of Catanzaro, Italy
    Clin Endocrinol (Oxf) 63:631-5. 2005
    ..Design Prospective controlled study...
  71. ncbi request reprint Are laparoscopic ovarian diathermy and gonadotropin administration the only therapeutic second-steps in clomiphene-citrate resistant women with polycystic ovary syndrome?
    Stefano Palomba
    Hum Reprod 19:2682-3; author reply 2683. 2004
  72. ncbi request reprint What is the best first-step therapeutic approach in treating anovulatory infertility in patients with polycystic ovary syndrome? Questions that are still unanswered
    Stefano Palomba
    Gynecol Endocrinol 23:245-7. 2007
  73. ncbi request reprint Lipid, glucose and homocysteine metabolism in women treated with a GnRH agonist with or without raloxifene
    Stefano Palomba
    Department of Obstetrics and Gynaecology, University of Catanzaro Magna Graecia, Catanzaro, Italy
    Hum Reprod 19:415-21. 2004
    ..Therefore, we have evaluated the effect of a GnRH analogue, administered with or without raloxifene, on serum levels of lipoproteins, glucose, insulin and homocysteine (Hcy)...
  74. ncbi request reprint Metformin administration versus laparoscopic ovarian diathermy in clomiphene citrate-resistant women with polycystic ovary syndrome: a prospective parallel randomized double-blind placebo-controlled trial
    Stefano Palomba
    Department of Gynecology and Obstetrics, University Magna Graecia of Catanzaro, Italy
    J Clin Endocrinol Metab 89:4801-9. 2004
    ..64.5%) rates were significantly (P < 0.05) different between the two groups. Our data show that metformin administration is more effective than LOD in overall reproductive outcomes in overweight infertile CC-resistant women with PCOS...
  75. ncbi request reprint Effect of estrogen replacement plus low-dose alendronate treatment on bone density in surgically postmenopausal women with osteoporosis
    Stefano Palomba
    Obstetrics and Gynecology, University of Catanzaro, 88100 Catanzaro, Italy
    J Clin Endocrinol Metab 87:1502-8. 2002
    ....
  76. ncbi request reprint Clomiphene citrate versus metformin as first-line approach for the treatment of anovulation in infertile patients with polycystic ovary syndrome
    Stefano Palomba
    Department of Gynecology and Obstetrics, University Magna Graecia of Catanzaro, Via Pio X, 88100 Catanzaro, Italy
    J Clin Endocrinol Metab 92:3498-503. 2007
    ..Clomiphene citrate (CC) and metformin are two effective drugs used to induce ovulation in patients with polycystic ovary syndrome (PCOS), even if it is still unclear which compound between them should be initially administered...
  77. ncbi request reprint Long-term effectiveness and safety of GnRH agonist plus raloxifene administration in women with uterine leiomyomas
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Italy
    Hum Reprod 19:1308-14. 2004
    ..Our aim was to evaluate the long-term effectiveness and safety of GnRH agonist plus raloxifene administration in women with symptomatic uterine leiomyomas...
  78. ncbi request reprint Dose reduction and discontinuation of alendronate in postmenopausal osteoporotic women who were receiving estrogen therapy
    Stefano Palomba
    Fertil Steril 81:476-8. 2004
    ..Low-dose alendronate is as effective as standard-dose alendronate, and its effects continue after drug withdrawal in postmenopausal osteoporotic women who are being treated with estrogen...
  79. ncbi request reprint BsmI vitamin D receptor genotypes influence the efficacy of antiresorptive treatments in postmenopausal osteoporotic women. A 1-year multicenter, randomized and controlled trial
    Stefano Palomba
    Department of Obstetrics and Gynaecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Osteoporos Int 16:943-52. 2005
    ..02), and not by the investigational centers involved in the study. In conclusion, in postmenopausal osteoporotic women, BsmI VDR genotypes influence the efficacy of antiresorptive drugs particularly when used in combination...
  80. ncbi request reprint Leuprolide acetate treatment with and without coadministration of tibolone in premenopausal women with menstrual cycle-related irritable bowel syndrome
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Via Nicolardi 188, Naples 80131, Italy
    Fertil Steril 83:1012-20. 2005
    ..To evaluate the effectiveness of gonadotropin-releasing hormone agonists (GnRH-a) with or without coadministration of tibolone in women with menstrual cycle-related irritable bowel syndrome (IBS)...
  81. ncbi request reprint Ovarian size and blood flow in women with polycystic ovary syndrome and their correlations with endocrine parameters
    Enrico Carmina
    Department of Clinical Medicine, University of Palermo, Palermo, Italy
    Fertil Steril 84:413-9. 2005
    ....
  82. ncbi request reprint Efficacy of laparoscopic ovarian diathermy in clomiphene citrate-resistant women with polycystic ovary syndrome: relationships with chronological and ovarian age
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Gynecol Endocrinol 22:329-35. 2006
    ..The aim of the present study was to evaluate reproductive outcomes in clomiphene citrate (CC)-resistant PCOS patients treated with LOD according to ovarian and chronological age...
  83. ncbi request reprint Uterine effects of clomiphene citrate in women with polycystic ovary syndrome: a prospective controlled study
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Italy
    Hum Reprod 21:2823-9. 2006
    ....
  84. ncbi request reprint Tibolone reverses the cognitive effects caused by leuprolide acetate administration, improving mood and quality of life in patients with symptomatic uterine leiomyomas
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Fertil Steril 90:165-73. 2008
    ..To investigate the effects of tibolone co-administration with GnRH agonist treatment in terms of cognition, mood, and quality of life...
  85. ncbi request reprint Pretreatment with oral contraceptives in infertile anovulatory patients with polycystic ovary syndrome who receive gonadotropins for controlled ovarian stimulation
    Stefano Palomba
    Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Fertil Steril 89:1838-42. 2008
    ..No effect was observed in rates of cycle cancellation, pregnancy, abortion, live birth, multiple pregnancies, and ovarian hyperstimulation syndrome...
  86. ncbi request reprint Ultrasonography in polycystic ovary syndrome: an update
    Luciano G Nardo
    Department of Reproductive Medicine, St Mary s CMMC University Hospital, Manchester, UK
    J Reprod Med 52:390-6. 2007
    ....
  87. ncbi request reprint Raloxifene administration in women treated with gonadotropin-releasing hormone agonist for uterine leiomyomas: effects on bone metabolism
    Stefano Palomba
    Chair of Obstetrics and Gynecology, University of Catanzaro, 88100 Catanzaro, Italy
    J Clin Endocrinol Metab 87:4476-81. 2002
    ..In conclusion, raloxifene prevents GnRH-a related bone loss in premenopausal women with uterine leiomyomas...