Olivieri F, Recchioni R, Marcheselli F, Abbatecola A, Santini G, Borghetti G, et al
. Cellular senescence in cardiovascular diseases: potential age-related mechanisms and implications for treatment. Curr Pharm Des. 2013;19:1710-9 pubmed
..Finally, interventions aimed at improving the age-related decline in vascular cells during aging and disease, as well as strategies to harness the regenerative capacity of stem cells in CVD will be discussed. ..
Olivieri F, Antonicelli R, Spazzafumo L, Santini G, Rippo M, Galeazzi R, et al
. Admission levels of circulating miR-499-5p and risk of death in elderly patients after acute non-ST elevation myocardial infarction. Int J Cardiol. 2014;172:e276-8 pubmed publisher
Prattichizzo F, Bonafe M, Ceka A, Giuliani A, Rippo M, Re M, et al
. Endothelial Cell Senescence and Inflammaging: MicroRNAs as Biomarkers and Innovative Therapeutic Tools. Curr Drug Targets. 2016;17:388-97 pubmed
Gurău F, Baldoni S, Prattichizzo F, Espinosa E, Amenta F, Procopio A, et al
. Anti-senescence compounds: A potential nutraceutical approach to healthy aging. Ageing Res Rev. 2018;46:14-31 pubmed publisher
..We discuss the beneficial effects of polyphenol-rich foods in relation to the Mediterranean diet and the dietary habits of long-lived individuals, and examine their ability to modulate bacterial genera in the gut. ..
Olivieri F, Antonicelli R, Lorenzi M, D Alessandra Y, Lazzarini R, Santini G, et al
. Diagnostic potential of circulating miR-499-5p in elderly patients with acute non ST-elevation myocardial infarction. Int J Cardiol. 2013;167:531-6 pubmed publisher
..86 vs. cTnT AUC=0.68 and vs. hs-cTnT AUC=0.70). Circulating miR-499-5p is a sensitive biomarker of acute NSTEMI in the elderly, exhibiting a diagnostic accuracy superior to that of cTnT in patients with modest elevation at presentation. ..
Olivieri F, Galeazzi R, Giavarina D, Testa R, Abbatecola A, Ceka A, et al
. Aged-related increase of high sensitive Troponin T and its implication in acute myocardial infarction diagnosis of elderly patients. Mech Ageing Dev. 2012;133:300-5 pubmed publisher
..8 ng/L resulted the hs-cTnT cut-off value with the highest efficiency in AMI diagnosis of geriatric patients. Our data suggest that the hs-cTnT cut-off value must be age-tailored to improve the AMI diagnostic accuracy. ..
Olivieri F, Lazzarini R, Babini L, Prattichizzo F, Rippo M, Tiano L, et al
. Anti-inflammatory effect of ubiquinol-10 on young and senescent endothelial cells via miR-146a modulation. Free Radic Biol Med. 2013;63:410-20 pubmed publisher
..These phenomena may play a role in preventing the endothelial dysfunction associated with major age-related diseases. ..
Olivieri F, Antonicelli R, Recchioni R, Mariotti S, Marcheselli F, Lisa R, et al
. Telomere/telomerase system impairment in circulating angiogenic cells of geriatric patients with heart failure. Int J Cardiol. 2013;164:99-105 pubmed publisher
..CACs from CHF patients are characterized by telomere/telomerase system impairment, providing new insight into the clinical relevance of CACs in CHF pathogenesis. ..
Olivieri F, Spazzafumo L, Santini G, Lazzarini R, Albertini M, Rippo M, et al
. Age-related differences in the expression of circulating microRNAs: miR-21 as a new circulating marker of inflammaging. Mech Ageing Dev. 2012;133:675-85 pubmed publisher
..TGF-?R2 mRNA, a validated miR-21 target, showed the highest expression in the leukocytes from a subset of the octogenarians. Our findings suggest that miR-21 may be a new biomarker of inflammation. ..