David Nolan

Summary

Country: Italy

Publications

  1. ncbi ENPP1 Q121 variant, increased pulse pressure and reduced insulin signaling, and nitric oxide synthase activity in endothelial cells
    Simonetta Bacci
    Endocrine Unit, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini 1, San Giovanni Rotondo, Italy
    Arterioscler Thromb Vasc Biol 29:1678-83. 2009
  2. ncbi The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction
    Simonetta Bacci
    Unit of Endocrinology, CSS Scientific Institute, San Giovanni Rotondo, Italy
    Diabetes 54:3021-5. 2005
  3. ncbi Tag polymorphisms at the A20 (TNFAIP3) locus are associated with lower gene expression and increased risk of coronary artery disease in type 2 diabetes
    Watip Boonyasrisawat
    Section on Genetics and Epidemiology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA
    Diabetes 56:499-505. 2007
  4. ncbi A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes
    Yuan Yuan Zhang
    Research Division, Joslin Diabetes Center, Boston, Massachusetts 02215, USA
    Obesity (Silver Spring) 14:2119-26. 2006
  5. ncbi Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation
    Craig Pace
    Centre for Clinical Immunology and Biomedical Statistics, 2nd Floor, North Block, Royal Perth Hospital, Wellington Street, Perth 6000, Western Australia
    J Virol 80:9259-69. 2006
  6. ncbi Association of hGrb10 genetic variations with type 2 diabetes in Caucasian subjects
    Rosa Di Paola
    Diabetes Care 29:1181-3. 2006
  7. ncbi Efavirenz and CYP2B6 polymorphism: implications for drug toxicity and resistance
    David Nolan
    Clin Infect Dis 42:408-10. 2006
  8. ncbi HIV/AIDS. HIV: experiencing the pressures of modern life
    David Nolan
    Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital and Murdoch University, Perth, Western Australia 6000, Australia
    Science 307:1422-4. 2005
  9. ncbi Impact of host genetics on HIV disease progression and treatment: new conflicts on an ancient battleground
    David Nolan
    AIDS 18:1231-40. 2004
  10. ncbi Metabolic complications associated with HIV protease inhibitor therapy
    David Nolan
    Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital and Murdoch University, Perth, Western Australia, Australia
    Drugs 63:2555-74. 2003

Collaborators

  • Agostino Consoli
  • Sandra Mastroianno
  • Sabrina Prudente
  • Carlo Vigna
  • Assunta Pandolfi
  • Angelo Avogaro
  • Steven Shoelson
  • Simonetta Bacci
  • Vincenzo Trischitta
  • Rosa Di Paola
  • Alessandro Doria
  • Yuan Yuan Zhang
  • Watip Boonyasrisawat
  • Grazia Fini
  • Yuan-yuan Zhang
  • Jill Duffy
  • Claudia Menzaghi
  • Fabio Pellegrini
  • Craig Pace
  • Francesco Perticone
  • Roberto Baratta
  • Antonella Marucci
  • Lucia Frittitta
  • Patrizia Di Fulvio
  • Sara Di Silvestre
  • Gloria Formoso
  • Michael T Johnstone
  • Delphine Eberle
  • Ernest V Gervino
  • Silvana Gaudieri
  • Ester Ciociola
  • Christine Powers
  • Carmela Cisternino
  • Corey Moore
  • Maria Cristina Marescotti
  • Ryan Thompson
  • Giuseppe Miscio
  • Jean Keller
  • Vittorio Tassi
  • Lucia Gottardo
  • Simon Mallal
  • Ian James
  • Anna Rauseo
  • Cesare Amico
  • Lucia Salvemini
  • Ornella Ludovico
  • Davide Mangiacotti

Detail Information

Publications11

  1. ncbi ENPP1 Q121 variant, increased pulse pressure and reduced insulin signaling, and nitric oxide synthase activity in endothelial cells
    Simonetta Bacci
    Endocrine Unit, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini 1, San Giovanni Rotondo, Italy
    Arterioscler Thromb Vasc Biol 29:1678-83. 2009
    ..The genetic background of these 3 cardiovascular risk factors might be partly common. The ENPP1 K121Q polymorphism is associated with insulin resistance and cardiovascular risk...
  2. ncbi The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction
    Simonetta Bacci
    Unit of Endocrinology, CSS Scientific Institute, San Giovanni Rotondo, Italy
    Diabetes 54:3021-5. 2005
    ..In conclusion, the ENPP1/PC-1 121Q variant is associated with a progressive deterioration of the IR-atherogenic phenotype; among diabetic individuals, it is also associated with earlier onset of type 2 diabetes and MI...
  3. ncbi Tag polymorphisms at the A20 (TNFAIP3) locus are associated with lower gene expression and increased risk of coronary artery disease in type 2 diabetes
    Watip Boonyasrisawat
    Section on Genetics and Epidemiology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA
    Diabetes 56:499-505. 2007
    ..04 and 0.028, respectively). These findings point to variability in the A20/TNFAIP3 gene as a modulator of CAD risk in type 2 diabetes. This effect is mediated by allelic differences in A20 expression...
  4. ncbi A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes
    Yuan Yuan Zhang
    Research Division, Joslin Diabetes Center, Boston, Massachusetts 02215, USA
    Obesity (Silver Spring) 14:2119-26. 2006
    ..Our findings suggest that the visfatin/PBEF gene may play a role in determining T2D susceptibility, possibly by modulating chronic, low-grade inflammatory responses...
  5. ncbi Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation
    Craig Pace
    Centre for Clinical Immunology and Biomedical Statistics, 2nd Floor, North Block, Royal Perth Hospital, Wellington Street, Perth 6000, Western Australia
    J Virol 80:9259-69. 2006
    ..These data indicate that APOBEC3G-induced HIV-1 hypermutation represents a potent host antiviral factor in vivo and that the APOBEC3G-vif interaction may represent a valuable therapeutic target...
  6. ncbi Association of hGrb10 genetic variations with type 2 diabetes in Caucasian subjects
    Rosa Di Paola
    Diabetes Care 29:1181-3. 2006
  7. ncbi Efavirenz and CYP2B6 polymorphism: implications for drug toxicity and resistance
    David Nolan
    Clin Infect Dis 42:408-10. 2006
  8. ncbi HIV/AIDS. HIV: experiencing the pressures of modern life
    David Nolan
    Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital and Murdoch University, Perth, Western Australia 6000, Australia
    Science 307:1422-4. 2005
  9. ncbi Impact of host genetics on HIV disease progression and treatment: new conflicts on an ancient battleground
    David Nolan
    AIDS 18:1231-40. 2004
  10. ncbi Metabolic complications associated with HIV protease inhibitor therapy
    David Nolan
    Centre for Clinical Immunology and Biomedical Statistics, Royal Perth Hospital and Murdoch University, Perth, Western Australia, Australia
    Drugs 63:2555-74. 2003
    ....
  11. ncbi Tumour necrosis factor-alpha gene -238G/A promoter polymorphism associated with a more rapid onset of lipodystrophy
    David Nolan
    Centre for Clinical Immunology and Biomedical Statistics, and Department of Clinical Immunology and Biochemical Genetics, Royal Perth Hospital, Perth, Western Australia
    AIDS 17:121-3. 2003