Research Topics
Species | S GiuntaSummaryAffiliation: Neurobiology of Aging Laboratory Country: Italy Publications
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Detail Information
Publications
Transthyretin inhibition of amyloid beta aggregation and toxicityS Giunta
Laboratorio Analisi Chimico Cliniche, Microbiologiche e Diagnostica Molecolare, Ospedale Geriatrico INRCA IRCCS, Via della Montagnola 81, 60100 Ancona, Italy
Clin Biochem 38:1112-9. 2005..The aim of this study was to investigate transthyretin (prealbumin) effects on Abeta25-35-induced cytotoxicity...
The inflammation-sensitive protein alpha 1-anti-chymotrypsin neutralizes fibrillar aggregation and cytotoxicity of the beta-amyloid peptide more effectively than alpha 1-antitrypsinS Giunta
Laboratorio Analisi Chimico Cliniche, Microbiologiche e Diagnostica Molecolare, Ospedale Geriatrico INRCA IRCCS, Via della Montagnola 81, 60100, Ancona, Italy
Clin Biochem 40:887-92. 2007....
Transformation of beta-amyloid (A beta) (1-42) tyrosine to L-dopa as the result of in vitro hydroxyl radical attackS Giunta
Laboratorio Analisi Chimico Cliniche Microbiologiche e Diagnostica Molecolare INRCA, Ancona, Italy
Amyloid 7:189-93. 2000..These results lay the groundwork for further studies on modification and damage associated with the degenerative disorder in AD where oxidative stress and inflammation are known to occur...
Coenzyme Q10, antioxidant status and ApoE isoformsM Battino
Institute of Biochemistry, Facolta di Medicina, Universita Politecnica delle Marche, Ancona, Italy
Biofactors 18:299-305. 2003..The only E2 homozygous subject found had high levels of PON and low levels of CHP; the two E4/E4 subjects had low PON activity together with low levels of CHP...
Exploring the complex relations between inflammation and aging (inflamm-aging): anti-inflamm-aging remodelling of inflamm- aging, from robustness to frailtyS Giunta
Clinical Laboratory and Molecular Diagnostics, Geriatric Hospital INRCA IRCCS, 60100 Ancona, Italy
Inflamm Res 57:558-63. 2008..The same consequences also result the age-dependent decline of dehydroepiandrosterone (DHEA)...
