Antonio Cherubini

Summary

Affiliation: Neurobiology of Aging Laboratory
Country: Italy

Publications

  1. doi Subthreshold depression in older subjects: an unmet therapeutic need
    A Cherubini
    Department of Geriatrics, Research Hospital of Ancona, Italian National Research Center on Aging INRCA, Ancona, Italy
    J Nutr Health Aging 16:909-13. 2012
  2. doi Underrecognition and undertreatment of dementia in Italian nursing homes
    Antonio Cherubini
    Geriatric Hospital, Italian National Research Centres on Aging, Ancona, Italy
    J Am Med Dir Assoc 13:759.e7-13. 2012
  3. doi Underprescription of beneficial medicines in older people: causes, consequences and prevention
    Antonio Cherubini
    Geriatric Hospital, Italian National Research Centres on Aging INRCA, Ancona, Italy
    Drugs Aging 29:463-75. 2012
  4. pmc Uric acid and dementia in community-dwelling older persons
    Carmelinda Ruggiero
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Dement Geriatr Cogn Disord 27:382-9. 2009
  5. doi Predictors of hospitalization in Italian nursing home residents: the U.L.I.S.S.E. project
    Antonio Cherubini
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Italy
    J Am Med Dir Assoc 13:84.e5-10. 2012
  6. doi Potentially inappropriate drug prescriptions and risk of hospitalization among older, Italian, nursing home residents: the ULISSE project
    Carmelinda Ruggiero
    Department of Clinical and Experimental Medicine, Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy
    Drugs Aging 27:747-58. 2010
  7. doi Inappropriate drug prescriptions among older nursing home residents: the Italian perspective
    Carmelinda Ruggiero
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Drugs Aging 26:15-30. 2009
  8. pmc Plasma soluble gp130 levels are increased in older subjects with metabolic syndrome. The role of insulin resistance
    Giovanni Zuliani
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology and Geriatrics, University of Ferrara, Via Savonarola No 9, 44100 Ferrara, Italy
    Atherosclerosis 213:319-24. 2010
  9. ncbi The prevention of adverse drug reactions in older subjects
    Antonio Cherubini
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Italy
    Curr Drug Metab 12:652-7. 2011
  10. ncbi Cognitive impairment is the major risk factor for development of geriatric syndromes during hospitalization: results from the GIFA study
    Patrizia Mecocci
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce Padiglione E, Via Brunamonti 51, IT 06122 Perugia, Italy
    Dement Geriatr Cogn Disord 20:262-9. 2005

Detail Information

Publications24

  1. doi Subthreshold depression in older subjects: an unmet therapeutic need
    A Cherubini
    Department of Geriatrics, Research Hospital of Ancona, Italian National Research Center on Aging INRCA, Ancona, Italy
    J Nutr Health Aging 16:909-13. 2012
    ..There is an urgent need to reach a consensus concerning the diagnostic criteria for subthreshold depression as well as to perform clinical trials to identify effective and safe therapies in this too long neglected patient group...
  2. doi Underrecognition and undertreatment of dementia in Italian nursing homes
    Antonio Cherubini
    Geriatric Hospital, Italian National Research Centres on Aging, Ancona, Italy
    J Am Med Dir Assoc 13:759.e7-13. 2012
    ..To determine the prevalence of dementia diagnoses and the use of antidementia drugs in a cohort of Italian older nursing home (NH) residents...
  3. doi Underprescription of beneficial medicines in older people: causes, consequences and prevention
    Antonio Cherubini
    Geriatric Hospital, Italian National Research Centres on Aging INRCA, Ancona, Italy
    Drugs Aging 29:463-75. 2012
    ..Since START criteria are easier to apply in clinical practice than other instruments, it is conceivable that their systematic use may contribute to reducing underprescribing and to improving health outcomes in older patients...
  4. pmc Uric acid and dementia in community-dwelling older persons
    Carmelinda Ruggiero
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Dement Geriatr Cogn Disord 27:382-9. 2009
    ..Epidemiological studies found that hyperuricemia is associated with conditions leading to dementia. Our aim is to investigate the relationship between UA levels and dementia in older persons...
  5. doi Predictors of hospitalization in Italian nursing home residents: the U.L.I.S.S.E. project
    Antonio Cherubini
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Italy
    J Am Med Dir Assoc 13:84.e5-10. 2012
    ..To examine resident and facility characteristics associated with hospitalization in a cohort of Italian older nursing home residents...
  6. doi Potentially inappropriate drug prescriptions and risk of hospitalization among older, Italian, nursing home residents: the ULISSE project
    Carmelinda Ruggiero
    Department of Clinical and Experimental Medicine, Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy
    Drugs Aging 27:747-58. 2010
    ..Little information is available about the prevalence of potentially inappropriate drug prescriptions (PIDPs) and the related health adverse outcomes among nursing home (NH) residents...
  7. doi Inappropriate drug prescriptions among older nursing home residents: the Italian perspective
    Carmelinda Ruggiero
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Drugs Aging 26:15-30. 2009
    ..Overall, this review reveals that the prevalence of PIDP is high in both North American and European nursing homes and highlights the urgent need for intervention trials testing strategies to reduce the health and social burden of PIDP...
  8. pmc Plasma soluble gp130 levels are increased in older subjects with metabolic syndrome. The role of insulin resistance
    Giovanni Zuliani
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology and Geriatrics, University of Ferrara, Via Savonarola No 9, 44100 Ferrara, Italy
    Atherosclerosis 213:319-24. 2010
    ..This issue is important to clarify since signalling and "trans-signalling" affect different tissues. We investigated the relationship between MS and the interleukin-6 system in an older population...
  9. ncbi The prevention of adverse drug reactions in older subjects
    Antonio Cherubini
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Italy
    Curr Drug Metab 12:652-7. 2011
    ....
  10. ncbi Cognitive impairment is the major risk factor for development of geriatric syndromes during hospitalization: results from the GIFA study
    Patrizia Mecocci
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce Padiglione E, Via Brunamonti 51, IT 06122 Perugia, Italy
    Dement Geriatr Cogn Disord 20:262-9. 2005
    ..To detect the main factors associated with the occurrence of specific geriatric syndromes (namely pressure sores, fecal incontinence, urinary incontinence and falls) in elderly patients during hospitalization...
  11. ncbi Risk factors for short-term mortality in older subjects with acute ischemic stroke
    Giovanni Zuliani
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology and Geriatrics, University of Ferrara, Ferrara, Italy
    Gerontology 52:231-6. 2006
    ..The identification of predictors for mortality after stroke has a major importance for clinicians in order to allow the implementation of therapeutic and preventive strategies...
  12. doi Prior antiplatelet drug use and short-term mortality in older patients with acute ischemic stroke (AIS)
    Giovanni Zuliani
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology and Geriatrics, Arcispedale S Anna, University of Ferrara, Via Savonarola 9, I 44100 Ferrara, Italy
    Arch Gerontol Geriatr 54:214-7. 2012
    ..72). We conclude that in older patients hospitalized for "major" AIS, prior use of AA was not associated with any benefit in terms of short-term mortality both in patients with first, as well as in those with recurrent ischemic stroke...
  13. pmc Low plasma N-3 fatty acids and dementia in older persons: the InCHIANTI study
    Antonio Cherubini
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    J Gerontol A Biol Sci Med Sci 62:1120-6. 2007
    ..N-3 fatty acids (FA) have an important role in brain development and function. However, there is conflicting evidence concerning the relationship between n-3 FA and dementia in older persons...
  14. ncbi Interaction of CTSD and A2M polymorphisms in the risk for Alzheimer's disease
    Elena Mariani
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    J Neurol Sci 247:187-91. 2006
    ..Our data suggest that the CTSD-T allele of the CTSD-C/T polymorphism is associated with an increased relative risk for late-onset AD and, more interestingly, the combination of CTSD-T with the A2M-G allele seems to increase this risk...
  15. doi The persistent exclusion of older patients from ongoing clinical trials regarding heart failure
    Antonio Cherubini
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, Policlinico Santa Maria della Misericordia, University of Perugia Medical School, Piazzale Menghini 1, 06156 Perugia PG, Italy
    Arch Intern Med 171:550-6. 2011
    ..A good example is heart failure. Therefore, we investigated the extent of exclusion of older individuals in ongoing clinical trials regarding heart failure...
  16. ncbi A multi-dimensional questionnaire quantifying quality of life in elderly osteoporotic women: the Italian triple-Q osteoporosis study
    Dario Maggio
    Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
    Aging Clin Exp Res 22:330-9. 2010
    ..We also examined specific aspects of the questionnaire correlated with bone mineral density...
  17. ncbi Potential markers of oxidative stress in stroke
    Antonio Cherubini
    Institute of Gerontology and Geriatrics, University of Perugia Medical School, Policlinico Monteluce Pad E, Via Brunamonti 51, 06122 Perugia, Italy
    Free Radic Biol Med 39:841-52. 2005
    ....
  18. pmc The UP-TECH project, an intervention to support caregivers of Alzheimer's disease patients in Italy: study protocol for a randomized controlled trial
    Carlos Chiatti
    Italian National Research Center on Aging, Ancona, Italy
    Trials 14:155. 2013
    ..The main objectives of the UP-TECH project are: 1) to reduce the care burden of family caregivers of AD patients; and 2) to maintain AD patients at home...
  19. doi Improving the diagnostic accuracy of depression in older persons: the Depression in the Aged Female National Evaluation cluster randomized trial
    Fabrizia Lattanzio
    Research Department, Istituto Nazionale Riposo e Cura Anziani, Ancona, Italy
    J Am Geriatr Soc 57:588-93. 2009
    ..To evaluate whether a training intervention can improve the ability of geriatricians to recognize depression in older persons...
  20. doi Chronic kidney disease and 1-year survival in elderly patients discharged from acute care hospitals: a comparison of three glomerular filtration rate equations
    Andrea Corsonello
    Unit of Geriatric Pharmacoepidemiology, Italian National Research Centres on Aging, Cosenza, Italy
    Nephrol Dial Transplant 26:360-4. 2011
    ..We aimed at comparing the association between GFR estimated using three different formulas and 1-year survival in elderly patients discharged from acute care hospitals...
  21. ncbi Pattern of use and presenting complaints of older patients visiting an Emergency Department in Italy
    Fabio Salvi
    Department of Geriatrics and Emergency Care, Italian National Research Centres on Aging I N R C A, Ancona, Italy
    Aging Clin Exp Res 25:583-90. 2013
    ..Similarly, no data are available about the reasons to ED visit and its role in determining the ED utilization pattern. The study aimed at describing the pattern of ED use by older patients and main presenting complaints...
  22. doi Adverse drug events as a cause of hospitalization in older adults
    Fabio Salvi
    Geriatrics and Geriatric Emergency Care, Italian National Research Centres on Aging INRCA, Via della Montagnola n 81, 60127, Ancona, Italy
    Drug Saf 35:29-45. 2012
    ....
  23. ncbi Conversion of MCI to dementia: Role of proton magnetic resonance spectroscopy
    Antonio Metastasio
    Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Via Brunamonti 51, 06122 Perugia, Italy
    Neurobiol Aging 27:926-32. 2006
    ..48+/-0.08) and sMCI (1.65+/-0.12) and between pMCI and controls (1.63+/-0.16) in the left hemisphere, suggesting that this metabolic alteration can be detected before the clinical appearance of dementia...
  24. ncbi Treatment with angiotensin-converting enzyme inhibitors is associated with a reduction in short-term mortality in older patients with acute ischemic stroke
    Giovanni Zuliani
    Department of Clinical and Experimental Medicine, Section of Internal Medicine, Gerontology and Geriatrics, University of Ferrara, 44100 Ferrara, Italy
    J Gerontol A Biol Sci Med Sci 60:463-5. 2005
    ..We tested the hypothesis that angiotensin-converting enzyme inhibitors (A-I) might affect short-term (30 day) mortality in older persons with severe acute ischemic stroke...