Research Topics
| Mauro SerafiniSummaryAffiliation: National Institute for Food and Nutrition Research Country: Italy Publications
| Collaborators
|
Detail Information
Publications
Understanding the association between dietary antioxidants, redox status and disease: is the Total Antioxidant Capacity the right tool?Mauro Serafini
Antioxidant Research Laboratory, Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
Redox Rep 9:145-52. 2004..Finally, the feasibility of the 'TAC concept' as an innovative tool for investigating the association between diet and oxidative stress is discussed...- Total antioxidant potential of fruit and vegetables and risk of gastric cancerMauro Serafini
Antioxidant Research Laboratory, Unit of Human Nutrition, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione INRAN, Rome, Italy
Gastroenterology 123:985-91. 2002..We investigated whether the total dietary antioxidant potential of fruit and vegetables is an appropriate means of estimating the antioxidant impact on gastric cancer risk in a large population-based study... - Effect of acute ingestion of fresh and stored lettuce (Lactuca sativa) on plasma total antioxidant capacity and antioxidant levels in human subjectsMauro Serafini
Antioxidant Research Laboratory at the Unit of Human Nutrition, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione INRAN, Rome, Italy
Br J Nutr 88:615-23. 2002..Further research is needed to develop post-harvesting techniques able to preserve the bioactive molecule content of plant food... - Plasma antioxidants from chocolateMauro Serafini
Antioxidant Research Laboratory, Unit of Human Nutrition, National Institute for Food and Nutrition Research, Via Ardeatina 546, 00178 Rome, Italy
Nature 424:1013. 2003 
Antioxidant activity of blueberry fruit is impaired by association with milkMauro Serafini
Antioxidant Research Laboratory, Unit of Human Nutrition, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, 00178 Rome, Italy
Free Radic Biol Med 46:769-74. 2009..001). The ingestion of blueberries in association with milk, thus, impairs the in vivo antioxidant properties of blueberries and reduces the absorption of caffeic acid...- Redox molecules and cancer prevention: the importance of understanding the role of the antioxidant networkMauro Serafini
Antioxidant Research Laboratory at the Unit of Human Nutritional, National Institute for Food and Nutrition Research, Rome, Italy
Nutr Cancer 56:232-40. 2006..The feasibility of TAC assessment as an innovative tool for investigating the association between dietary antioxidants, oxidative stress, and cancer will be also discussed... - Biomarkers of antioxidant status following ingestion of green teas at different polyphenol concentrations and antioxidant capacity in human volunteersMonia Pecorari
Antioxidant Research Laboratory, Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, Rome, Italy
Mol Nutr Food Res 54:S278-83. 2010..6 and 1.4 g/L. An evidence for a linear correlation between GTFT antioxidant content and the extent of the antioxidant effect in vivo has been provided... - High fat meal increase of IL-17 is prevented by ingestion of fruit juice drink in healthy overweight subjectsIlaria Peluso
Antioxidant Research Laboratory, INRAN Via Ardeatina 546, 00178 Rome, Italy
Curr Pharm Des 18:85-90. 2012..037). We provided, for the first time, evidence on the role of diet in modulating IL-17 production in healthy overweight subjects... - Redox ingredients for oxidative stress prevention: the unexplored potentiality of coffeeMauro Serafini
Antioxidant Research Laboratory, Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
Clin Dermatol 27:225-9. 2009..In this contribution after describing the main contributors to dietary TAC for different plant food group, we will discuss the potentiality of coffee as a source of "ready to drink" reducing equivalents... - Dietary total antioxidant capacity and gastric cancer risk in the European prospective investigation into cancer and nutrition studyMauro Serafini
Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione, Rome, Italy
Int J Cancer 131:E544-54. 2012..lowest quintile: adjusted HR 0.4; 95%CI (0.21-0.75) p < 0.05); no association was observed for TRAP. Dietary antioxidant capacity intake from different sources of plant foods is associated with a reduction in the risk of GC... - Total antioxidant capacity of spices, dried fruits, nuts, pulses, cereals and sweets consumed in Italy assessed by three different in vitro assaysNicoletta Pellegrini
Antioxidant Research Laboratory at the Unit of Human Nutrition, National Institute for Food and Nutrition Research, Rome, Italy
Mol Nutr Food Res 50:1030-8. 2006..The complete TAC database could be utilized to properly investigate the role of dietary antioxidants in disease prevention... - Oxidative Stress in Atherosclerosis Development: The Central Role of LDL and Oxidative BurstIlaria Peluso
CRA exINRAN, Via Ardeatina, 546, 00178 Rome, Italy
Endocr Metab Immune Disord Drug Targets 12:351-60. 2012..Understanding the relationship between oxLDL and leukocyte oxidative burst helps to explain the involvement of innate immune responses in the early phases of atherosclerosis. The present review focuses on this interplay... - Flavonoids as anti-inflammatory agentsMauro Serafini
Antioxidant Research Laboratory, INRAN, Via Ardeatina 546, 00178 Rome, Italy
Proc Nutr Soc 69:273-8. 2010..Human trials with appropriate placebo and pure flavonoid molecules are needed to clarify if flavonoids represent ancillary ingredients or key molecules involved in the anti-inflammatory properties of plant foods... - The Role of Polyphenols in the Modulation of Plasma Non-Enzymatic Antioxidant Capacity (NEAC)Mauro Serafini
Antioxidant Research Laboratory, National Institute for Food and Nutrition Research, Rome, Italy
Int J Vitam Nutr Res 82:228-32. 2012..This work will discuss the role of polyphenols from galenic preparation, food extracts, and selected dietary sources as modulators of plasma NEAC in humans... - Lymphocytes as internal standard in oxidative burst analysis by cytometry: a new data analysis approachIlaria Peluso
Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione INRAN, Rome, Italy
J Immunol Methods 379:61-5. 2012..In addition, this method is sensitive to differences in healthy subjects due to sub-pathological conditions, such as hypercholesterolemia... - Effect of changes in fruit and vegetable intake on plasma antioxidant defenses in humansMauro Serafini
Am J Clin Nutr 81:531-2; author reply 532-4. 2005 - Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assaysNicoletta Pellegrini
Department of Public Health, University of Parma, Parma, Italy
J Nutr 133:2812-9. 2003..Such data, coupled with an appropriate questionnaire to estimate antioxidant intake, will allow the investigation of the relation between dietary antioxidants and oxidative stress-induced diseases... - Bioavailability of pelargonidin-3-O-glucoside and its metabolites in humans following the ingestion of strawberries with and without creamWilliam Mullen
Plant Products and Human Nutrition Group, Graham Kerr Building, Division of Environmental and Evolutionary Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom
J Agric Food Chem 56:713-9. 2008..In keeping with these observations, measurement of plasma paracetamol and breath hydrogen revealed that cream delayed gastric emptying and extended mouth to cecum transit time... - The validity and reproducibility of food-frequency questionnaire-based total antioxidant capacity estimates in Swedish womenSusanne Rautiainen
Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
Am J Clin Nutr 87:1247-53. 2008..Total antioxidant capacity (TAC) provides an assessment of antioxidant activity and synergistic interactions of redox molecules in foods and plasma... - Dark chocolate improves coronary vasomotion and reduces platelet reactivityAndreas J Flammer
Cardiovascular Center, Cardiology, University Hospital Zurich, Raemistr 100, CH 8091 Zurich, Switzerland
Circulation 116:2376-82. 2007..Thus, flavonoid-rich dark chocolate holds the potential to have a beneficial impact on graft atherosclerosis... - Endemic species of sardo-corso-balearic area: molecular composition and biological assay of TeucriumFerruccio Poli
Dipartimento di Biologia Sperimentale ed Evoluzionistica, Universita di Bologna, 40126 Bologna, Italy
Nat Prod Res 21:1061-6. 2007..The polar extracts showed antioxidant activity in vitro. Verbascoside and arabinosyl-verbascoside were isolated and identified. Their concentrations were in connection to the antioxidant activity... - The occurrence of phenyl propanoid glycosides in endemic Teucrium speciesAnna Maria Serrilli
Consorzio interuniversitario COSMESE, Dipartimento di Chimica, Universita di Roma La Sapienza
Nat Prod Res 21:814-8. 2007..Comparison with molecular composition of T. marum confirmed the differences between these species and evidenced their endemic character... - Do flavan-3-ols from green tea reach the human brain?Andrea Zini
Department of Neuroscience, University of Modena and Reggio Emilia, Modena, Italy
Nutr Neurosci 9:57-61. 2006..Alternatively, a systemic action may be hypothesised whereby dietary flavan-3-ols up-regulate antioxidant defences and/or reduce inflammation, the benefit of which may be effective throughout the body... - Taxonomical markers in two endemic plants of Sardinia: Verbascum conocarpum and Scrophularia trifoliataAlessia Ramunno
Dipartimento di Chimica, Piazzale Aldo Moro, 5 00185 Roma
Nat Prod Res 20:511-6. 2006..The main chemotaxonomic markers of Scrophulariaceae, the iridoids aucubin, verbascoside and catalpol, were isolated... - Flavonoids and iridoids from Stachys corsicaAnna Maria Serrilli
Dipartimento di Chimica, Universita di Roma La Sapienza, Piazzale Aldo Moro, 5 00185 Roma, Italy
Nat Prod Res 19:561-5. 2005..All the compounds have previously been isolated from other species of Stachys... - Total antioxidant capacity of the diet is inversely and independently related to plasma concentration of high-sensitivity C-reactive protein in adult Italian subjectsFurio Brighenti
Department of Public Health, University of Parma, Parma, Italy
Br J Nutr 93:619-25. 2005..This could be of particular significance for subjects with high blood pressure... - Effect on rat arterial blood pressure of chemically generated peroxyl radicals and protection by antioxidantsIlaria Peluso
Department of Pharmacology of Natural Substances and General Physiology, La Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy
J Nutr Biochem 15:323-7. 2004..Other experiments are needed to clarify the role played by oxidative potentials on blood pressure and the mechanism of action of nutritional antioxidants... - Mechanism of vitamin E inhibition of cyclooxygenase activity in macrophages from old mice: role of peroxynitriteAlison A Beharka
Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Free Radic Biol Med 32:503-11. 2002..These findings have important implications for designing interventions to reverse and/or delay age-associated dysregulation of immune and inflammatory responses and diseases associated with them...