Aldo Quattrone

Summary

Affiliation: National Research Council
Country: Italy

Publications

  1. pmc Genetic variation in the myeloperoxidase gene and cognitive impairment in multiple sclerosis
    I Manna
    Institute of Neurological Science, National Research Council, Cosenza, Italy
    J Negat Results Biomed 5:3. 2006
  2. ncbi Myocardial 123metaiodobenzylguanidine uptake in genetic Parkinson's disease
    Aldo Quattrone
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Mov Disord 23:21-7. 2008
  3. ncbi MR imaging index for differentiation of progressive supranuclear palsy from Parkinson disease and the Parkinson variant of multiple system atrophy
    Aldo Quattrone
    Institute of Neurology, Magna Graecia University of Catanzaro, Catanzaro, Calabria, Italy
    Radiology 246:214-21. 2008
  4. doi Essential head tremor is associated with cerebellar vermis atrophy: a volumetric and voxel-based morphometry MR imaging study
    A Quattrone
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    AJNR Am J Neuroradiol 29:1692-7. 2008
  5. doi Ventro-lateral prefrontal activity during working memory is modulated by MAO A genetic variation
    Antonio Cerasa
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Brain Res 1201:114-21. 2008
  6. doi Mutation analysis of the SPG4 gene in Italian patients with pure and complicated forms of spastic paraplegia
    Angela Magariello
    Institute of Neurological Sciences, National Research Council, 87050 Mangone, Cosenza, Italy
    J Neurol Sci 288:96-100. 2010
  7. ncbi Impact of individual cognitive profile on visuo-motor reorganization in relapsing-remitting multiple sclerosis
    Maria Cecilia Gioia
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, 87050, Cosenza, Italy
    Brain Res 1167:71-9. 2007
  8. ncbi Preliminary evidences of a NOS2A protective effect from relapsing-remitting multiple sclerosis
    Ida Manna
    Institute of Neurological Sciences, National Research Council, Contrada Burga 87050 Pianolago di Mangone CS, Italy
    J Neurol Sci 264:112-7. 2008
  9. ncbi Sex differences in clinical and genetic determinants of levodopa peak-dose dyskinesias in Parkinson disease: an exploratory study
    Mario Zappia
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Arch Neurol 62:601-5. 2005
  10. doi MAO A VNTR polymorphism and variation in human morphology: a VBM study
    Antonio Cerasa
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Neuroreport 19:1107-10. 2008

Detail Information

Publications112 found, 100 shown here

  1. pmc Genetic variation in the myeloperoxidase gene and cognitive impairment in multiple sclerosis
    I Manna
    Institute of Neurological Science, National Research Council, Cosenza, Italy
    J Negat Results Biomed 5:3. 2006
    ..We did not find significant differences in allele or genotype distributions between impaired and preserved MS patients. Our findings suggest that MPO polymorphism is not a risk factor for cognitive impairment in MS...
  2. ncbi Myocardial 123metaiodobenzylguanidine uptake in genetic Parkinson's disease
    Aldo Quattrone
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Mov Disord 23:21-7. 2008
    ..Our findings also demonstrate that MIGB uptake has a heterogeneous pattern in genetic PD, because it was differently impaired in patients with different mutations in the same gene or with the same gene mutation...
  3. ncbi MR imaging index for differentiation of progressive supranuclear palsy from Parkinson disease and the Parkinson variant of multiple system atrophy
    Aldo Quattrone
    Institute of Neurology, Magna Graecia University of Catanzaro, Catanzaro, Calabria, Italy
    Radiology 246:214-21. 2008
    ....
  4. doi Essential head tremor is associated with cerebellar vermis atrophy: a volumetric and voxel-based morphometry MR imaging study
    A Quattrone
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    AJNR Am J Neuroradiol 29:1692-7. 2008
    ..Our aim was to investigate the presence of brain gray matter (GM) abnormalities in patients with different forms of essential tremor (ET)...
  5. doi Ventro-lateral prefrontal activity during working memory is modulated by MAO A genetic variation
    Antonio Cerasa
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Brain Res 1201:114-21. 2008
    ..Moreover, given the well-known role of this area in inhibitory control, our finding also provides new evidence for the involvement of 5-HT in PFC-mediated WM function...
  6. doi Mutation analysis of the SPG4 gene in Italian patients with pure and complicated forms of spastic paraplegia
    Angela Magariello
    Institute of Neurological Sciences, National Research Council, 87050 Mangone, Cosenza, Italy
    J Neurol Sci 288:96-100. 2010
    ..4% (3/14). Furthermore, we found a mutational rate of 22.2% (2/9) and 41.4% (12/29) in the complicated and pure forms, respectively. The results underlie the importance of genetic testing in all affected individuals...
  7. ncbi Impact of individual cognitive profile on visuo-motor reorganization in relapsing-remitting multiple sclerosis
    Maria Cecilia Gioia
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, 87050, Cosenza, Italy
    Brain Res 1167:71-9. 2007
    ..This study addresses the relative effects of cognitive impairment and brain atrophy on the cortical reorganization associated with a visuo-motor task...
  8. ncbi Preliminary evidences of a NOS2A protective effect from relapsing-remitting multiple sclerosis
    Ida Manna
    Institute of Neurological Sciences, National Research Council, Contrada Burga 87050 Pianolago di Mangone CS, Italy
    J Neurol Sci 264:112-7. 2008
    ..In conclusion, we found that the NOS2A (CCTTT)(14) allele was detected more frequently in the control group than in the RRMS patients, thus confirming the scientific interest on this marker...
  9. ncbi Sex differences in clinical and genetic determinants of levodopa peak-dose dyskinesias in Parkinson disease: an exploratory study
    Mario Zappia
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Arch Neurol 62:601-5. 2005
    ....
  10. doi MAO A VNTR polymorphism and variation in human morphology: a VBM study
    Antonio Cerasa
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Neuroreport 19:1107-10. 2008
    ..This study reveals pronounced genotype-related structural changes in a specific prefrontal region previously observed to mediate neurofunctional responses in behavioral tasks...
  11. ncbi Increased risk for Alzheimer disease with the interaction of MPO and A2M polymorphisms
    Mario Zappia
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Arch Neurol 61:341-4. 2004
    ..Two polymorphic sites in these genes (MPO-G/A and A2M-Ile/Val) have been associated with Alzheimer disease (AD), but conflicting findings have been reported in populations with different ethnic backgrounds...
  12. doi Impact of catechol-O-methyltransferase Val(108/158) Met genotype on hippocampal and prefrontal gray matter volume
    Antonio Cerasa
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone 87050, Cosenza, Italy
    Neuroreport 19:405-8. 2008
    ..This study provides evidence that the Val(108/158)Met polymorphism of the COMT gene might be responsible for individual variation in the human brain morphology...
  13. ncbi Dopaminergic modulation of cognitive interference after pharmacological washout in Parkinson's disease
    Francesco Fera
    Neuroradiology Unit, University Magna Graecia, Catanzaro, Italy
    Brain Res Bull 74:75-83. 2007
    ..When a true hypodopaminergic state is induced in PD patients, cognitive interference might significantly benefit from the administration of levodopa via an enhanced PFC response...
  14. doi Prefrontal alterations in Parkinson's disease with levodopa-induced dyskinesia during fMRI motor task
    Antonio Cerasa
    Neuroimaging Research Unit, Institute of Neurological Sciences, National Research Council, Germaneto CZ, Italy
    Mov Disord 27:364-71. 2012
    ..This functional magnetic resonance imaging study together with our previous volumetric findings highlights the role of the prefrontal cortex in the neuronal mechanisms of dyskinesia...
  15. doi Fronto-parietal overactivation in patients with essential tremor during Stroop task
    Antonio Cerasa
    Neuroimaging Research Unit, Institute of Neurological Sciences, National Research Council, Catanzaro, Italy
    Neuroreport 21:148-51. 2010
    ..Our study shows that patients with essential tremor require additional cognitive effort to achieve comparable performance levels on test of attentional control...
  16. doi The effects of BDNF Val66Met polymorphism on brain function in controls and patients with multiple sclerosis: an imaging genetic study
    Antonio Cerasa
    Neuroimaging Research Unit, Institute of Neurological Sciences, National Research Council, Germaneto CZ 88100, Italy
    Behav Brain Res 207:377-86. 2010
    ....
  17. ncbi Electroclinical features of a family with simple febrile seizures and temporal lobe epilepsy associated with SCN1A loss-of-function mutation
    Eleonora Colosimo
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Epilepsia 48:1691-6. 2007
    ..We showed that the mutation is associated with a loss of SCN1A function...
  18. doi A longitudinal observation of brain-derived neurotrophic factor mRNA levels in patients with relapsing-remitting multiple sclerosis
    Maria Liguori
    Institute of Neurological Sciences, National Research Council, Contrada Burga, Mangone, Cosenza 87050, Italy
    Brain Res 1256:123-8. 2009
    ..Although with caution due to the small sample size, it also underscores the potential role of the Val66Met polymorphism on the peripheral BDNF expression in RRMS. Functional studies are needed to better clarify this issue...
  19. doi Compound heterozygosity in DJ-1 gene non-coding portion related to parkinsonism
    Patrizia Tarantino
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Parkinsonism Relat Disord 15:324-6. 2009
    ..Our results support the growing importance of mutations in non-coding portion of human genome, and confirm that alterations in DJ-1 are a cause, even if rare, of early-onset Parkinson's disease...
  20. doi Failure to confirm association of a polymorphism in KCNMB4 gene with mesial temporal lobe epilepsy
    Ida Manna
    Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    Epilepsy Res 106:284-7. 2013
    ..They further highlight the importance of replication to confirm the validity of association study results...
  21. ncbi Association between Synapsin III gene promoter polymorphisms and multiple sclerosis
    Maria Liguori
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    J Neurol 251:165-70. 2004
    ....
  22. ncbi Apparent diffusion coefficient measurements of the middle cerebellar peduncle differentiate the Parkinson variant of MSA from Parkinson's disease and progressive supranuclear palsy
    Giuseppe Nicoletti
    Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    Brain 129:2679-87. 2006
    ..Our findings indicate that, in order to substantially contribute to the in vivo differential diagnosis of MSA-P, PSP and Parkinson's disease, rADC measurements should not be limited to the basal ganglia but should also include the MCP...
  23. doi Diffusivity of cerebellar hemispheres enables discrimination of cerebellar or parkinsonian multiple system atrophy from progressive supranuclear palsy-Richardson syndrome and Parkinson disease
    Giuseppe Nicoletti
    Institute of Neurologic Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Radiology 267:843-50. 2013
    ..To explore the usefulness of histogram analysis of mean diffusivity (MD) derived from diffusion-weighted imaging of large infratentorial structures to distinguish parkinsonian syndromes...
  24. doi Neurobiological mechanisms underlying emotional processing in relapsing-remitting multiple sclerosis
    Luca Passamonti
    Istituto di Scienze Neurologiche, Consiglio Nazionale delle Ricerche, Cosenza, 87050, Italy
    Brain 132:3380-91. 2009
    ..Overall our findings offer new insights into the neurobiological mechanisms of emotions in multiple sclerosis and provide evidence that they resemble those described for some psychiatric disorders...
  25. doi Apparent diffusion coefficient of the superior cerebellar peduncle differentiates progressive supranuclear palsy from Parkinson's disease
    Giuseppe Nicoletti
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Mov Disord 23:2370-6. 2008
    ....
  26. doi Age at onset influences neurodegenerative processes underlying PD with levodopa-induced dyskinesias
    Antonio Cerasa
    Neuroimaging Research Unit, Institute of Neurological Sciences, National Research Council, Germaneto, CZ, Italy
    Parkinsonism Relat Disord 19:883-8. 2013
    ....
  27. ncbi ApoE epsilon4 allele and disease duration affect verbal learning in mild temporal lobe epilepsy
    Antonio Gambardella
    Institute of Neurology, School of Medicine, Catanzaro, Italy
    Epilepsia 46:110-7. 2005
    ..To clarify the possible role of other factors including the ApoE epsilon4 allele for memory decline in temporal lobe epilepsy (TLE)...
  28. doi Blink reflex recovery cycle in patients with essential tremor associated with resting tremor
    Rita Nisticò
    Department of Medical Sciences, University Magna Graecia, Cosenza, Italy
    Neurology 79:1490-5. 2012
    ..We studied BRrc in patients with ET associated with resting tremor (rET) in comparison with patients with ET...
  29. doi Presenilin enhancer-2 gene: identification of a novel promoter mutation in a patient with early-onset familial Alzheimer's disease
    Virginia Andreoli
    Institute of Neurological Sciences, National Research Council, Pianolago di Mangone, Cosenza, Italy
    Alzheimers Dement 7:574-8. 2011
    ..Although the effective role of the PEN-2 promoter deletion in AD is not entirely clear, these findings might lead to more studies on its functional and genetic role...
  30. ncbi Association between the M129V variant allele of PRNP gene and mild temporal lobe epilepsy in women
    Angelo Labate
    Institute of Neurology, School of Medicine, University of Catanzaro, Catanzaro, Italy
    Neurosci Lett 421:1-4. 2007
    ..006, OR=1.632; 95%CI=1.15-2.31). This is the first publication of data that support the hypothesis that the common methionine/valine polymorphism at codon 129 of the PRNP gene may modify the susceptibility of women to mild TLE...
  31. doi Increased prefrontal volume in PD with levodopa-induced dyskinesias: a voxel-based morphometry study
    Antonio Cerasa
    Neuroimaging Research Unit, Institute of Neurological Sciences, National Research Council, Germaneto CZ, Italy
    Mov Disord 26:807-12. 2011
    ..Our findings suggest that the presence of dyskinesias in patients with PD is characterized by an aberrant neural plasticity that could play a role in the pathophysiology of these motor complications...
  32. ncbi Altered cortical-cerebellar circuits during verbal working memory in essential tremor
    Luca Passamonti
    National Research Council, Neuroimaging Research Unit, Catanzaro, Italy
    Brain 134:2274-86. 2011
    ....
  33. ncbi Serotonin transporter gene (5-Htt): association analysis with temporal lobe epilepsy
    Ida Manna
    Institute of Neurological Sciences, National Research Council, Piano Lago Mangone Cosenza, Italy
    Neurosci Lett 421:52-6. 2007
    ..2% of patients were 10/10 versus 18.8% of controls). Haplotype analysis did not increase the evidence for association. These results suggest that the serotonin transporter gene may play a role in the etiology of TLE...
  34. ncbi MR imaging of middle cerebellar peduncle width: differentiation of multiple system atrophy from Parkinson disease
    Giuseppe Nicoletti
    Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    Radiology 239:825-30. 2006
    ..To prospectively assess if middle cerebellar peduncle (MCP) atrophy, evaluated at magnetic resonance (MR) imaging, can help differentiate multiple system atrophy (MSA) from Parkinson disease (PD)...
  35. doi Genetically dependent modulation of serotonergic inactivation in the human prefrontal cortex
    Luca Passamonti
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, 87050, Italy
    Neuroimage 40:1264-73. 2008
    ....
  36. doi Neurofunctional correlates of personality traits in relapsing-remitting multiple sclerosis: an fMRI study
    Maria C Gioia
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Brain Cogn 71:320-7. 2009
    ....
  37. doi MAO A VNTR polymorphism and amygdala volume in healthy subjects
    Antonio Cerasa
    Neuroimaging Research Unit, Institute of Neurological Sciences, National Research Council, Catanzaro, Italy
    Psychiatry Res 191:87-91. 2011
    ....
  38. ncbi Glucocerebrosidase gene mutations are associated with Parkinson's disease in southern Italy
    Elvira V De Marco
    Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    Mov Disord 23:460-3. 2008
    ..2%) had a heterozygous substitution (P = 0.0018). These results strongly suggest that Italian carriers of a GBA mutation have an increased risk of developing PD...
  39. doi Relationship between genetic variant in pre-microRNA-146a and genetic predisposition to temporal lobe epilepsy: a case-control study
    Ida Manna
    Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    Gene 516:181-3. 2013
    ..In conclusion, our data suggest that the rs2910164 variant in the pre-miR-146a gene is unlikely to influence significantly the risk of developing TLE or its severity...
  40. doi Association study between four polymorphisms in the HFE, TF and TFR genes and Parkinson's disease in southern Italy
    Valentina Greco
    Institute of Neurological Sciences, National Research Council, Contrada Burga, 87050 Mangone, Cosenza, Italy
    Neurol Sci 32:525-7. 2011
    ..No significant differences were found in genotype and allele frequencies between PD and controls for all the polymorphisms studied, suggesting that these variants do not contribute significantly to the risk of PD...
  41. doi Myocardial (123)I-MIBG scintigraphy for differentiation of Lewy bodies disease from FTD
    Fabiana Novellino
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Neurobiol Aging 31:1903-11. 2010
    ..86±0.20; delayed: 1.80±0.23) and in controls (H/M early: 1.91±0.17; delayed: 1.99±0.19), suggesting that cardiac (123)I-MIBG scintigraphy can help distinguish patients with LBD from those with FTD...
  42. ncbi Fas antigen and sporadic Alzheimer's disease in Southern Italy: evaluation of two polymorphisms in the TNFRSF6 gene
    Virginia Andreoli
    Institute of Neurological Sciences, National Research Council, C da Burga, Pianolago di Mangone, Italy
    Neurochem Res 32:1445-9. 2007
    ..No significant differences in allelic and genotypic distributions were found between cases and controls, or late and early-onset AD patients, thus suggesting that these polymorphisms do not represent an AD risk factor in our population...
  43. doi Combined use of DAT-SPECT and cardiac MIBG scintigraphy in mixed tremors
    Fabiana Novellino
    Department of Medical Sciences, Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Mov Disord 24:2242-8. 2009
    ..Our study suggests that the combined use of both DAT-SPECT and MIBG scintigraphy in mixed tremors with additional extrapyramidal features can help distinguish patients with ET from those with PD and parkinsonism...
  44. doi Morphological correlates of MAO A VNTR polymorphism: new evidence from cortical thickness measurement
    Antonio Cerasa
    Neuroimaging Research Unit, Institute of Neurological Sciences, National Research Council, Catanzaro, Italy
    Behav Brain Res 211:118-24. 2010
    ..In particular, thickness measurement of the orbitofrontal cortex provides new evidence about the biological impact of the MAO A genotype on neural systems relevant to the pathophysiology of behavioural disorders...
  45. doi Patterns of brain atrophy in Parkinson's disease, progressive supranuclear palsy and multiple system atrophy
    Demetrio Messina
    Institute of Neurological Sciences, National Research Council, Piano Lago, Mangone, Italy
    Parkinsonism Relat Disord 17:172-6. 2011
    ....
  46. doi A novel NF1 gene mutation in an Italian family with neurofibromatosis type 1
    Anna Lia Gabriele
    Institute of Neurological Science ISN, National Research Council CNR, Piano Lago di Mangone, Cosenza, Italy
    Childs Nerv Syst 27:635-8. 2011
    ..NF1 is caused by inactivating mutations of the 17q11.2-located NF1 gene. We present a clinical and molecular study of an Italian family with NF1...
  47. doi Single nucleotide polymorphism in the MMP-9 gene is associated with susceptibility to develop multiple sclerosis in an Italian case-control study
    Antonella La Russa
    Institute of Neurological Sciences, National Research Council, Cosenza, Italy
    J Neuroimmunol 225:175-9. 2010
    ..These results suggest that a genetic polymorphism of the MMP-9 promoter region may influence the susceptibility to MS...
  48. ncbi A novel point mutation in PMP22 gene in an Italian family with hereditary neuropathy with liability to pressure palsies
    Maria Muglia
    Institute of Neurological Sciences, National Research Council, Mangone Cosenza, Italy
    J Neurol Sci 263:194-7. 2007
    ..11delT). This novel mutation creates a shift on the reading frame starting at codon 4 and leads to the introduction of a premature stop at codon 6...
  49. ncbi Genetic heterogeneity in patients with pantothenate kinase-associated neurodegeneration and classic magnetic resonance imaging eye-of-the-tiger pattern
    Paola Valentino
    Institute of Neurology, University Magna Graecia Catanzaro, Catanzaro, Italy
    Mov Disord 21:252-4. 2006
    ..Therefore, the present observation reinforces the notion of the phenotypic and genetic heterogeneity in PKAN...
  50. ncbi Putative role of specific JAG1 gene exons in modulating clinical features in patients with leukoencephalopathy
    Carmine Ungaro
    Institute of Neurological Sciences, National Research Council, 87050 Mangone, Cosenza, Italy
    Neurosci Lett 418:1-3. 2007
    ..No mutations were found. These data demonstrate absence of correlation between mutations in specific JAG1 gene exons and clinical features in patients with CADASIL-like phenotype...
  51. pmc Sporadic ALS is not associated with VAPB gene mutations in Southern Italy
    Francesca Luisa Conforti
    Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    J Negat Results Biomed 5:7. 2006
    ..The frequency of the detected exon variation in the VAPB gene was not significantly different between patients and controls. In conclusion, our study suggests that VAPB mutations are not a common cause of adult-onset SALS...
  52. ncbi Mutational analysis of EFHC1 gene in Italian families with juvenile myoclonic epilepsy
    Ferdinanda Annesi
    Institute of Neurological Sciences, National Research Council, Mangone Cosenza, Italy
    Epilepsia 48:1686-90. 2007
    ..Mutations in the EFHC1 gene have been reported in six juvenile myoclonic epilepsy (JME) families from Mexico and Belize. In this study, we screened 27 unrelated JME Italian families for mutations in the EFHC1 gene...
  53. ncbi DJ-1 mutations and parkinsonism-dementia-amyotrophic lateral sclerosis complex
    Grazia Annesi
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Ann Neurol 58:803-7. 2005
    ..Both mutations cosegregated with the disease and were detected in a heterozygous state in the patients' mother and their healthy siblings. Our findings expand the spectrum of clinical presentations associated with mutations in DJ-1 gene...
  54. doi An magnetic resonance imaging T2*-weighted sequence at short echo time to detect putaminal hypointensity in Parkinsonisms
    Gennarina Arabia
    Institute of Neurology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Mov Disord 25:2728-34. 2010
    ..Despite the suboptimal sensitivity, the high specificity of the T2*/15 sequence performed on routine MRI suggests its usefulness in clinical practice for identifying putaminal hypointensities associated with parkinsonian disorders...
  55. doi Voxel-based morphometry of sporadic epileptic patients with mesiotemporal sclerosis
    Angelo Labate
    Institute of Neurology, University Magna Graecia, Viale Europa, Catanzaro, Italy
    Epilepsia 51:506-10. 2010
    ..Herein, we used optimized voxel-based morphometry (VBM) to identify GM abnormalities beyond the hippocampus in both rTLE and mTLE with evidence of MTS...
  56. doi Further evidence that D90A-SOD1 mutation is recessively inherited in ALS patients in Italy
    Francesca Luisa Conforti
    Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    Amyotroph Lateral Scler 10:58-60. 2009
    ..We investigated for the presence of this mutation in 169 unrelated ALS patients from southern Italy. The genetic analysis revealed three ALS patients (1.8%) with mild phenotype carrying the homozygous D90A mutation...
  57. doi Accuracy of magnetic resonance parkinsonism index for differentiation of progressive supranuclear palsy from probable or possible Parkinson disease
    Maurizio Morelli
    Institute of Neurology, University Magna Graecia, Germaneto, Catanzaro, Italy
    Mov Disord 26:527-33. 2011
    ..In this study, we evaluated the accuracy of MRPI, compared with midbrain/pons ratio, in distinguishing PSP from probable and possible PD...
  58. doi Cardiac MIBG scintigraphy in Primary Progressive Freezing Gait
    Maria Salsone
    Institute of Neurology, Department of Medical Sciences, University Magna Graecia, Catanzaro, Italy
    Parkinsonism Relat Disord 15:365-9. 2009
    ..17+/-0.02 early; 1.16+/-0.02 delayed; PD-FOG: 1.22+/-0.10 early; 1.08+/-0.06 delayed). Our findings demonstrate that cardiac sympathetic denervation did not occur in patients with PPFG, confirming that PPFG and PD are distinct diseases...
  59. doi Leber's hereditary optic neuropathy associated with a multiple-sclerosis-like picture in a man
    Antonella La Russa
    1Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    Mult Scler 17:763-6. 2011
    ....
  60. ncbi Novel spastin (SPG4) mutations in Italian patients with hereditary spastic paraplegia
    Angela Magariello
    Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    Neuromuscul Disord 16:387-90. 2006
    ..1322-2A>C). The frequency for SPG4 mutations detected in autosomal dominant hereditary spastic paraplegia was 44.4%. This study contributes to expand the spectrum of SPG4 mutations in Italian population...
  61. ncbi Comparison of different techniques for detecting 17p12 duplication in CMT1A
    Alessandra Patitucci
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Neuromuscul Disord 15:488-92. 2005
    ..However, in contrast to pulsed field gel electrophoresis, Real-Time PCR does not need fresh blood, minimizes diagnosis time and cost, and thus can be easily used for the molecular diagnosis of Charcot-Marie-Tooth type 1A...
  62. ncbi Brain iron deposition in essential tremor: a quantitative 3-Tesla magnetic resonance imaging study
    Fabiana Novellino
    Neuroimaging Research Unit, National Research Council, Catanzaro, Italy
    Mov Disord 28:196-200. 2013
    ..Our results are suggestive of a possible involvement of motor systems outside of the cerebellum/cerebellar pathway and, more specifically, of the globus pallidus...
  63. doi FUS mutations in sporadic amyotrophic lateral sclerosis: clinical and genetic analysis
    William Sproviero
    Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    Neurobiol Aging 33:837.e1-5. 2012
    ..41G>A; c.523+3ins[GAGGTG]; c.335-15del[TTTT]; and rs13331793) in 9 patients from within our cohort. This study underlines the importance of population-based mutation screening of newly identified genes...
  64. ncbi FRAXE intermediate alleles are associated with Parkinson's disease
    Grazia Annesi
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Neurosci Lett 368:21-4. 2004
    ..4%) subjects with PD and in only one of the 370 (0.27%) healthy controls (P < 0.001), thus indicating that these relatively large alleles may be associated with PD...
  65. pmc An axon regeneration signature in a Charcot-Marie-Tooth disease type 2 patient
    Francesca Cavalcanti
    Institute of Neurological Sciences, National Research Council, Mangone, Cosenza, Italy
    J Neurogenet 23:324-8. 2009
    ..Additionally, Lamin A/C, which is mutated in CMT2B1, was overexpressed in the patient, suggesting that CMT-causing genes may interact in a regulatory network...
  66. ncbi Further evidence of genetic heterogeneity in autosomal dominant distal motor neuronopathy
    Luca Passamonti
    Institute of Neurological Sciences, Ospedale Regionale Torrette, University Ancona, Ancona, Italy
    Neuromuscul Disord 14:705-10. 2004
    ..The analysis was negative thus excluding a complicated form of autosomal dominant hereditary spastic paraparesis. These data further confirm a genetic heterogeneity within inherited motor neuronopathy...
  67. ncbi Contribution of cerebrospinal fluid thymosin β4 levels to the clinical differentiation of Creutzfeldt-Jakob disease
    Maria Le Pera
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Arch Neurol 69:868-72. 2012
    ..To asses thymosin β4 specificity as relevant to the diagnosis of Creutzfeldt-Jakob disease (CJD)...
  68. doi Dysbindin C-A-T haplotype is associated with thicker medial orbitofrontal cortex in healthy population
    Antonio Cerasa
    Neuroimaging Research Unit, Institute of Neurological Sciences, National Research Council, Catanzaro, Italy
    Neuroimage 55:508-13. 2011
    ....
  69. doi Age at onset predicts good seizure outcome in sporadic non-lesional and mesial temporal sclerosis based temporal lobe epilepsy
    Umberto Aguglia
    Institute of Neurology, University Magna Græcia, Catanzaro, Italy
    J Neurol Neurosurg Psychiatry 82:555-9. 2011
    ..To study prognosis and prognostic predictors of sporadic non-lesional temporal lobe epilepsy (TLE)...
  70. doi Charcot-Marie-Tooth and pain: correlations with neurophysiological, clinical, and disability findings
    Luca Padua
    Institute of Neurology, Università Cattolica del Sacro Cuore and Fondazione Don Carlo Gnocchi, Rome, Italy
    Neurol Sci 29:193-4. 2008
    ..Our study underlined that pain should be considered as a relevant symptom in CMT patients and further studies should be performed...
  71. ncbi Further evidence of genetic heterogeneity in families with autosomal dominant nocturnal frontal lobe epilepsy
    Elvira V De Marco
    Institute of Neurological Sciences, National Research Council, Mangone CS, Italy
    Epilepsy Res 74:70-3. 2007
    ....
  72. ncbi No evidence of association between the alpha-2 macroglobulin gene and Parkinson's disease in a case-control sample
    Giuseppe Nicoletti
    Institute of Experimental Medicine and Biotechnology, National Research Council, Mangone CS, Italy
    Neurosci Lett 328:65-7. 2002
    ..The present data suggest that these polymorphisms do not represent a risk factor for PD and do not modulate the age at onset of PD...
  73. ncbi Usefulness of a morning routine EEG recording in patients with juvenile myoclonic epilepsy
    Angelo Labate
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Epilepsy Res 77:17-21. 2007
    ..To evaluate if a standard awake EEG recording in the morning is superior to afternoon awake EEG session in detecting generalized epileptiform discharges (GEDs) in patients with juvenile myoclonic epilepsy (JME)...
  74. ncbi Temporal lobe epilepsy as a unique manifestation of multiple sclerosis
    Antonio Gambardella
    Institute of Neurology, School of Medicine, Catanzaro, Italy
    Can J Neurol Sci 30:228-32. 2003
    ..To report on five patients with temporal lobe epilepsy (TLE) as the unique manifestation of multiple sclerosis (MS)...
  75. ncbi Adaptive cortical changes and the functional correlates of visuo-motor integration in relapsing-remitting multiple sclerosis
    Antonio Cerasa
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza 87050, Italy
    Brain Res Bull 69:597-605. 2006
    ..Moreover these results confirm the potential for functional recovery and the adaptive role of these areas in the motor reorganization of multiple sclerosis patients...
  76. doi Casimir Funk: his discovery of the vitamins and their deficiency disorders
    Anna Piro
    Institute of Neurological Science, Consiglio Nazionale delle Ricerche, Contrada Burga, Mangone, Italy
    Ann Nutr Metab 57:85-8. 2010
    ..In 1911, he designated these factors 'vitamins' ('vita' = life, and 'amine' = a nitrogenous substance essential for life); this name was accepted by the scientific community in 1912...
  77. doi Clinical, genetic and magnetic resonance findings in an Italian patient affected by L-2-hydroxyglutaric aciduria
    Rosalucia Mazzei
    Institute of Neurological Sciences, National Research Council, Loc Burga, 87050, Piano Lago di Mangone CS, Italy
    Neurol Sci 32:95-9. 2011
    ....
  78. doi NOS2A as a candidate gene in Relapsing-Remitting Multiple Sclerosis: a haplotype study using selected subsets of single nucleotide polymorphisms
    Ida Manna
    Institute of Neurological Science, National Research Council, Cosenza, Italy
    J Neurol Sci 304:75-7. 2011
    ..Defining the haplotype blocks also failed to detect any associated haplotypes. Our results suggest that polymorphic variation within the NOS2A gene does not influence the susceptibility to MS in patients of Italian origin...
  79. ncbi A simple method for diagnosis of autosomal recessive spinal muscular atrophy by denaturing high-performance liquid chromatography
    Rosalucia Mazzei
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    J Child Neurol 18:269-71. 2003
    ..In this study, we describe a new method to detect SMN gene deletion by denaturing high-performance liquid chromatography, which is also simple to perform but is faster and more specific...
  80. doi Paul Ehrlich: the Nobel Prize in physiology or medicine 1908
    Anna Piro
    Istituto di Scienze Neurologiche CNR, Mangone, Cosenza, Italy
    Int Rev Immunol 27:1-17. 2008
    ..We have used some original documents from the Royal Society of London, where Ehrlich was a fellow, and from Leipzig University, where he took a degree in medicine...
  81. ncbi Two-dimensional gel electrophoresis of peripheral nerve proteins: Optimized sample preparation
    Antonio Qualtieri
    Institute of Neurological Sciences, National Research Council CNR, Contrada Burga, 87050 Mangone, Cosenza, Italy
    J Neurosci Methods 159:125-33. 2007
    ..The reported experimental procedures appear to be essential for 2DE separation of peripheral nerve proteins for the establishment of a reference map...
  82. ncbi Lack of association between estrogen receptor 1 gene polymorphisms and multiple sclerosis in southern Italy in humans
    Giovanni Savettieri
    Institute of Neurology, University of Palermo, Palermo, Italy
    Neurosci Lett 327:115-8. 2002
    ..This result suggests that the association between a given disease and a genomic characteristic must be confirmed by separate investigations in different populations...
  83. ncbi Tacrolimus-induced polyneuropathy after heart transplantation
    Angelo Labate
    Institute of Neurology, University Magna Graecia of Catanzaro, Catanzaro, Italy
    Clin Neuropharmacol 33:161-2. 2010
    ..This condition suddenly reverted after the tacrolimus was stopped...
  84. doi Proteomic profiling of cerebrospinal fluid in Creutzfeldt-Jakob disease
    Antonio Qualtieri
    Institute of Neurological Sciences, National Research Council, Contrada Burga, Mangone, Cosenza, Italy
    Expert Rev Proteomics 7:907-17. 2010
    ..In this article, the existing data regarding prion infection, biomarkers for CJD diagnosis and the use of several modern proteomic technologies for the identification of new cerebrospinal fluid polypeptides involved in CJD are reviewed...
  85. ncbi Prodynorphin gene promoter polymorphism and temporal lobe epilepsy
    Antonio Gambardella
    Institute of Neurology, School of Medicine, Catanzaro, Italy
    Epilepsia 44:1255-6. 2003
  86. ncbi Familial essential tremor is not associated with SCA-12 mutation in southern Italy
    Giuseppe Nicoletti
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    Mov Disord 17:837-8. 2002
    ..We investigated 30 patients with familial essential tremor (ET) for spinocerebellar ataxia type 12 (SCA-12) mutations. No patient presented a CAG repeat larger than 19, suggesting that familial ET and SCA-12 are distinct diseases...
  87. ncbi Body weight influences pharmacokinetics of levodopa in Parkinson's disease
    Mario Zappia
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Clin Neuropharmacol 25:79-82. 2002
    ..This could explain gender differences for the development of LD-induced peak-dose dyskinesias observed during the course of the disease...
  88. ncbi A large family with pure autosomal dominant hereditary spastic paraplegia from southern Italy mapping to chromosome 14q11.2-q24.3
    Maria Muglia
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    J Neurol 249:1413-6. 2002
    ..3 years. Significant linkage to the SPG3 locus on chromosome 14 was detected. The authors also report their search for mutations in a gene located in the region and its exclusion as a candidate for SPG3...
  89. ncbi A novel mutation in the CLN1 gene in a patient with juvenile neuronal ceroid lipofuscinosis
    Rosalucia Mazzei
    Institute of Neurological Sciences, National Research Council, Piano Lago di Mangone, Cosenza, Italy
    J Neurol 249:1398-400. 2002
    ..This analysis revealed a novel mutation in homozygous form in the exon 7 that caused an aminoacid substitution at codon 222 (Leu --> Pro). Direct sequencing of the exon 7 in both parents showed the same substitution in heterozygous form...
  90. ncbi Movement time and aging: a normative study in healthy subjects with the "Movement Time Analyzer"
    Giuseppe Nicoletti
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Aging Clin Exp Res 17:207-10. 2005
    ..The Movement Time Analyzer (MTA) is a simple, objective and reliable instrument to study MT, but no normative study has been reported to date...
  91. ncbi Hormonal replacement therapy in women with Parkinson disease and levodopa-induced dyskinesia: a crossover trial
    Alessandra Nicoletti
    Department of Neurosciences, University of Catania, Via Santa Sofia no 78, 95123 Catania, Italy
    Clin Neuropharmacol 30:276-80. 2007
    ....
  92. ncbi Clinical and genetic findings in 26 Italian patients with Lafora disease
    Silvana Franceschetti
    Department of Clinical Neurophysiology, Istituto Nazionale Neurologico C Besta, Milan, Italy
    Epilepsia 47:640-3. 2006
    ..Genotype-phenotype correlations suggested that EPM2B patients show a slower course of the disease, with delayed age at death, compared with EPM2A patients. We herein report clinical and genetic findings of 26 Italian LD patients...
  93. ncbi Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease
    Demetrius M Maraganore
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    JAMA 296:661-70. 2006
    ..Alpha-synuclein (SNCA) has been one of the most promising susceptibility genes, but large-scale studies have been lacking...
  94. doi A phenotypic variation of dominant optic atrophy and deafness (ADOAD) due to a novel OPA1 mutation
    Maria Liguori
    J Neurol 255:127-9. 2008
  95. ncbi Interaction between Apolipoprotein epsilon 4 and traumatic brain injury in patients with Alzheimer's disease and Mild Cognitive Impairment
    Marco Mauri
    Section of Neurology, Department of Clinical Medicine, Universita dell Insubria, Varese, Italy
    Funct Neurol 21:223-8. 2006
    ..Our data do not suggest that the presence of these two factors influences the clinical presentation or the course of the disease...
  96. ncbi Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability
    Gioacchino Tedeschi
    Department of Neurological Sciences, Second University of Naples, Naples, Italy
    J Neurol Sci 263:15-9. 2007
    ..Fatigue is a major problem in multiple sclerosis (MS), and its association with MRI features is debated...
  97. ncbi Motor response to apomorphine in patients with Parkinson's disease with long-duration response to levodopa
    Ubaldo Bonuccelli
    Department of Neuroscience, University of Pisa, Pisa, Italy
    Clin Neuropharmacol 25:119-21. 2002
    ..e., postsynaptic versus presynaptic) or transduction pathways are involved in such responses...
  98. pmc Identification of an Nav1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures
    Massimo Mantegazza
    Department of Neurophysiopathogy, Istituto Neurologico C Besta, Milan, Italy
    Proc Natl Acad Sci U S A 102:18177-82. 2005
    ..Thus, M145T is a loss-of-function mutant. These results show that monogenic FS should also be considered a channelopathy...
  99. ncbi Identification of the novel D297fsX318 PINK1 mutation and phenotype variation in a family with early-onset Parkinson's disease
    Giovanni Savettieri
    Department of Clinical Neurosciences, University of Palermo, Italy
    Parkinsonism Relat Disord 14:509-12. 2008
    ..The present study supports the view that PINK1 is a pathogenic gene in some Italian families with EOPD and contributes to define the PINK1-associated phenotype...
  100. ncbi Chronic bilateral subthalamic deep brain stimulation in a patient with homozygous deletion in the parkin gene
    Marianna Capecci
    Dipartimento di Scienze Neurologiche, Universita Politecnica delle Marche, Ospedale Regionale Torrette, Ancona, Italy
    Mov Disord 19:1450-2. 2004
    ....
  101. ncbi Monoamine oxidase-a genetic variations influence brain activity associated with inhibitory control: new insight into the neural correlates of impulsivity
    Luca Passamonti
    Neurology Unit, Department of Neurosciences, University Politecnica delle Marche, Ancona, Italy
    Biol Psychiatry 59:334-40. 2006
    ..High-activity allele carriers have higher enzyme expression, lower amine concentration, and present higher scores on behavioral measures of impulsivity than low-activity allele carriers...