Research Topics
| Emanuele NasoleSummaryCountry: Italy Publications
|
Detail Information
Publications
Lymphocyte DNA damage precedes DNA repair or cell death after orthopaedic surgery under general anaesthesiaRenata Alleva
Department of Anaesthesiology, Rizzoli Orthopaedic Institute, Via Pupilli, 40136 Bologna, Italy
Mutagenesis 18:423-8. 2003..In conclusion, the actual risk from anaesthesia is presumably extremely small. However, these findings contribute to our understanding of the regulation of DNA damage/repair and cell death...
Alpha-tocopheryl succinate induces cytostasis and apoptosis in osteosarcoma cells: the role of E2F1Renata Alleva
Department of Anaesthesiology, Rizzoli Orthopaedic Institute, 40100 Bologna, Italy
Biochem Biophys Res Commun 331:1515-21. 2005..Knocking down E2F1 rendered the alpha-TOS-sensitive cells rather resistant to the apoptotic stimulus inducing a marked and prolonged cell growth arrest. We conclude that alpha-TOS induces cell growth arrest or apoptosis involving E2F1...
alpha-Lipoic acid supplementation inhibits oxidative damage, accelerating chronic wound healing in patients undergoing hyperbaric oxygen therapyRenata Alleva
Department of Anesthesiology, IRCCS Istituti Ortopedici Rizzoli, Bologna, Italy
Biochem Biophys Res Commun 333:404-10. 2005..Taken together, we demonstrated an adjuvant effect of LA in HBO therapy used for impaired wound healing treatment. We propose that LA may be used to further promote the beneficial effects of HBO therapy...
Alpha-tocopheryl succinate alters cell cycle distribution sensitising human osteosarcoma cells to methotrexate-induced apoptosisRenata Alleva
Department of Anesthesiology, IRCCS Istituti Ortopedici Rizzoli, Via Pupilli, 40136 Bologna, Italy
Cancer Lett 232:226-35. 2006..We propose that alpha-TOS may be used as a drug or an adjuvant for treatment of osteosarcomas...
alpha-Lipoic acid modulates extracellular matrix and angiogenesis gene expression in non-healing wounds treated with hyperbaric oxygen therapyRenata Alleva
Department of Anesthesiology, IRCCS Istituti Ortopedici Rizzoli, Bologna, Italy
Mol Med 14:175-83. 2008..The disruption of the positive autocrine feedback loops that maintain the chronic wound state promotes progression of the healing process...
