P Mulatero

Summary

Country: Italy

Publications

  1. ncbi request reprint Comparison of confirmatory tests for the diagnosis of primary aldosteronism
    Paolo Mulatero
    Centro Ipertensione Ospedale San Vito, Strada San Vito 34, 10133, Torino, Italy
    J Clin Endocrinol Metab 91:2618-23. 2006
  2. doi request reprint Effect of adrenocorticotropic hormone stimulation during adrenal vein sampling in primary aldosteronism
    Silvia Monticone
    Department of Physiology, Georgia Health Sciences University, Augusta, GA, USA
    Hypertension 59:840-6. 2012
  3. doi request reprint 18-hydroxycorticosterone, 18-hydroxycortisol, and 18-oxocortisol in the diagnosis of primary aldosteronism and its subtypes
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, Division of Internal Medicine and Hypertension Unit, University of Torino, and Clinical Chemistry Laboratory, San Giovanni Battista University Hospital, Via Genova 3, 10126 Torino, Italy
    J Clin Endocrinol Metab 97:881-9. 2012
  4. doi request reprint Aldosterone as an independent factor in cerebrovascular damage
    Paolo Mulatero
    Division of Internal Medicine and Hypertension, Department of Medicine and Experimental Oncology, University of Torino, Torino, Italy
    Clin Exp Hypertens 30:785-97. 2008
  5. ncbi request reprint A particular phenotype in a girl with aldosterone synthase deficiency
    Tracy A Williams
    Department of Medicine and Experimental Oncology, Hypertension Unit, San Vito Hospital, Strada San Vito 34, 10133 Turin, Italy
    J Clin Endocrinol Metab 89:3168-72. 2004
  6. doi request reprint Prevalence and characteristics of familial hyperaldosteronism: the PATOGEN study (Primary Aldosteronism in TOrino-GENetic forms)
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, Division of Internal Medicine and Hypertension, University of Torino, Torino, Italy
    Hypertension 58:797-803. 2011
  7. doi request reprint Diagnosis and treatment of primary aldosteronism
    Paolo Mulatero
    Division of Internal Medicine and Hypertension, Department of Medicine and Experimental Oncology, University of Torino, 10126, Torino, Italy
    Rev Endocr Metab Disord 12:3-9. 2011
  8. doi request reprint Evaluation of primary aldosteronism
    Paolo Mulatero
    Division of Internal Medicine and Hypertension, Department of Medicine and Experimental Oncology, University of Torino, Torino, Italy
    Curr Opin Endocrinol Diabetes Obes 17:188-93. 2010
  9. ncbi request reprint Mineralocorticoid receptor blockade in the protection of target organ damage
    Paolo Mulatero
    Ospedale San Vito, Strada San Vito 34, 10133 Torino, Italy
    Cardiovasc Hematol Agents Med Chem 4:75-91. 2006
  10. ncbi request reprint CYP11B2 -344T/C gene polymorphism and blood pressure in patients with acromegaly
    Paolo Mulatero
    Division of Internal Medicine, Hypertension Unit, Ospedale San Vito, Strada San Vito 34, 10133 Torino, Italy
    J Clin Endocrinol Metab 91:5008-12. 2006

Collaborators

Detail Information

Publications65

  1. ncbi request reprint Comparison of confirmatory tests for the diagnosis of primary aldosteronism
    Paolo Mulatero
    Centro Ipertensione Ospedale San Vito, Strada San Vito 34, 10133, Torino, Italy
    J Clin Endocrinol Metab 91:2618-23. 2006
    ..The FST is considered by many to be the most reliable but is more complex and expensive...
  2. doi request reprint Effect of adrenocorticotropic hormone stimulation during adrenal vein sampling in primary aldosteronism
    Silvia Monticone
    Department of Physiology, Georgia Health Sciences University, Augusta, GA, USA
    Hypertension 59:840-6. 2012
    ..Stringent criteria for cannulation should be used to have a high consistency of the diagnosis...
  3. doi request reprint 18-hydroxycorticosterone, 18-hydroxycortisol, and 18-oxocortisol in the diagnosis of primary aldosteronism and its subtypes
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, Division of Internal Medicine and Hypertension Unit, University of Torino, and Clinical Chemistry Laboratory, San Giovanni Battista University Hospital, Via Genova 3, 10126 Torino, Italy
    J Clin Endocrinol Metab 97:881-9. 2012
    ..Diagnosis of primary aldosteronism (PA) is made by screening, confirmation testing, and subtype diagnosis (computed tomography scan and adrenal vein sampling). However, some tests are costly and unavailable in most hospitals...
  4. doi request reprint Aldosterone as an independent factor in cerebrovascular damage
    Paolo Mulatero
    Division of Internal Medicine and Hypertension, Department of Medicine and Experimental Oncology, University of Torino, Torino, Italy
    Clin Exp Hypertens 30:785-97. 2008
    ..Herein we review the pathophysiology of aldosterone action in the brain and the clinical and experimental studies on the detrimental effects of aldosterone in the brain...
  5. ncbi request reprint A particular phenotype in a girl with aldosterone synthase deficiency
    Tracy A Williams
    Department of Medicine and Experimental Oncology, Hypertension Unit, San Vito Hospital, Strada San Vito 34, 10133 Turin, Italy
    J Clin Endocrinol Metab 89:3168-72. 2004
    ..This case of ASD is of particular interest because despite the apparent lack of aldosterone synthase activity, the patient displays low-normal aldosterone levels, thus raising the question of its source...
  6. doi request reprint Prevalence and characteristics of familial hyperaldosteronism: the PATOGEN study (Primary Aldosteronism in TOrino-GENetic forms)
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, Division of Internal Medicine and Hypertension, University of Torino, Torino, Italy
    Hypertension 58:797-803. 2011
    ....
  7. doi request reprint Diagnosis and treatment of primary aldosteronism
    Paolo Mulatero
    Division of Internal Medicine and Hypertension, Department of Medicine and Experimental Oncology, University of Torino, 10126, Torino, Italy
    Rev Endocr Metab Disord 12:3-9. 2011
    ..In the present review we describe briefly the published diagnostic strategies of the Guidelines, highlighting new evidence that has become recently available and discuss issues that still need to be addressed by future research...
  8. doi request reprint Evaluation of primary aldosteronism
    Paolo Mulatero
    Division of Internal Medicine and Hypertension, Department of Medicine and Experimental Oncology, University of Torino, Torino, Italy
    Curr Opin Endocrinol Diabetes Obes 17:188-93. 2010
    ..The purpose of this review is to briefly summarize current knowledge on diagnosis and treatment of primary aldosteronism, the most frequent cause of endocrine hypertension...
  9. ncbi request reprint Mineralocorticoid receptor blockade in the protection of target organ damage
    Paolo Mulatero
    Ospedale San Vito, Strada San Vito 34, 10133 Torino, Italy
    Cardiovasc Hematol Agents Med Chem 4:75-91. 2006
    ..We also discuss the pharmacological and clinical differences between the two available mineralocorticoid receptor blockers, spironolactone and eplerenone...
  10. ncbi request reprint CYP11B2 -344T/C gene polymorphism and blood pressure in patients with acromegaly
    Paolo Mulatero
    Division of Internal Medicine, Hypertension Unit, Ospedale San Vito, Strada San Vito 34, 10133 Torino, Italy
    J Clin Endocrinol Metab 91:5008-12. 2006
    ..The pathogenesis of increased blood pressure (BP) in acromegaly is unclear, and the role of IGF-I levels and the renin-angiotensin-aldosterone system (RAAS) in this disease remains controversial...
  11. ncbi request reprint [Role of aldosterone in the metabolic syndrome]
    P Mulatero
    Divisione di Medicina Interna e Ipertensione, Universita di Torino, Torino
    G Ital Nefrol 23:406-14. 2006
    ..Higher rates of cardiovascular events have been recently reported in primary aldosteronism: they could be partly due to the increased prevalence of the metabolic syndrome in this disorder...
  12. doi request reprint Confirmatory tests in the diagnosis of primary aldosteronism
    P Mulatero
    Division of Internal Medicine, Department of Medicine and Experimental Oncology, University of Torino, Torino, Italy
    Horm Metab Res 42:406-10. 2010
    ..Herein we discuss the diagnostic protocols for these confirmatory tests and highlight both the advantages and contraindications and we discuss studies in which these confirmatory tests have been compared...
  13. ncbi request reprint Diagnosis and treatment of low-renin hypertension
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, Division of Internal Medicine and Hypertension, University of Torino, Italy
    Clin Endocrinol (Oxf) 67:324-34. 2007
    ..The present review will discuss the differential diagnosis of LRH subtypes and the most appropriate treatment options based on the pathophysiological background of this condition...
  14. ncbi request reprint Differential diagnosis of primary aldosteronism subtypes
    Paolo Mulatero
    Division of Internal Medicine and Hypertension, AOU San Giovanni Battista, Via Genova 3, 10126, Torino, Italy
    Curr Hypertens Rep 11:217-23. 2009
    ..This article reviews the strategies to correctly identify PA subtypes, underlining the central role of adrenal vein sampling...
  15. doi request reprint Impact of different diagnostic criteria during adrenal vein sampling on reproducibility of subtype diagnosis in patients with primary aldosteronism
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, University of Torino, Torino, Italy
    Hypertension 55:667-73. 2010
    ..75. In conclusion, permissive criteria for successful cannulation and lateralization on AVS achieve poor diagnostic reproducibility and should be avoided...
  16. doi request reprint Roles of clinical criteria, computed tomography scan, and adrenal vein sampling in differential diagnosis of primary aldosteronism subtypes
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, University of Torino, 10126 Torino, Italy
    J Clin Endocrinol Metab 93:1366-71. 2008
    ..Because AVS is not widely available, a list of clinical criteria that indicate the presence of an aldosterone-producing adenoma (APA) has been suggested...
  17. ncbi request reprint Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents
    Paolo Mulatero
    Hypertension Unit, Department of Medicine and Experimental Oncology, University of Torino, 10133 Turin, Italy
    J Clin Endocrinol Metab 89:1045-50. 2004
    ..In conclusion, the wide use of the ARR as a screening test in hypertensive patients led to a marked increase in the detection rate of PA...
  18. ncbi request reprint Genetics of primary aldosteronism
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, San Vito Hospital, University of Torino, Torino, Italy
    J Hypertens 22:663-70. 2004
    ..Here, we review the genetic and the phenotypic features of the familial forms, the genetic variants that influence the sporadic forms and the structure and regulation of the CYP11B1 and CYP11B2 genes...
  19. ncbi request reprint Blood pressure in patients with primary aldosteronism is influenced by bradykinin B(2) receptor and alpha-adducin gene polymorphisms
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, Hypertension Unit, San Vito Hospital, University of Turin, Strada San Vito 34, 10133 Turin, Italy
    J Clin Endocrinol Metab 87:3337-43. 2002
    ..0% of the systolic and diastolic blood pressure variance, respectively. These data suggest that genetic variants of alpha-adducin and the bradykinin B(2)-R influence the blood pressure levels in patients with primary aldosteronism...
  20. ncbi request reprint Hypertension, genotype and oral contraceptives
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, Hypertension Unit, San Vito Hospital, University of Torino, S San Vito 34 10133 Torino, Italy
    Pharmacogenomics 3:57-63. 2002
    ..In this article, the epidemiology and the pathogenesis of OCIH are reviewed with particular emphasis on the genetic influence in light of the most recent studies in this field...
  21. ncbi request reprint Glucocorticoid remediable aldosteronism: low morbidity and mortality in a four-generation italian pedigree
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, Hypertension Unit, San Vito Hospital, University of Turin, Strada San Vito 34, 10133 Turin, Italy
    J Clin Endocrinol Metab 87:3187-91. 2002
    ..However, none of the biochemical or genetic parameters investigated could explain the mild phenotype of the family...
  22. ncbi request reprint Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, Hypertension Unit, University of Torino, Torino, Italy
    Hypertension 40:897-902. 2002
    ..The high rate of false-negative diagnoses in patients undergoing irbesartan treatment requires confirmation in a higher number of patients...
  23. doi request reprint KCNJ5 mutations in European families with nonglucocorticoid remediable familial hyperaldosteronism
    Paolo Mulatero
    Division of Internal Medicine and Hypertension, University of Torino, Torino, Italy
    Hypertension 59:235-40. 2012
    ..In conclusion, we describe herein a new mutation in the KCNJ5 potassium channel associated with FH-III, responsible for marked alterations of channel function but associated with a mild clinical and hormonal phenotype...
  24. doi request reprint Adrenal endothelin-1 levels are not associated with aldosterone secretion in primary aldosteronism
    F Morello
    Fourth Division of Internal Medicine and Hypertension Unit, San Giovanni Battista Hospital of Torino, University of Torino, Torino, Italy
    Eur J Endocrinol 160:453-8. 2009
    ..Hence, the existence of a feedforward loop involving ETs and aldosterone has been speculated in primary aldosteronism (PA). In the present study, we sought to examine ET-1 secretion from the adrenal glands in patients with PA...
  25. ncbi request reprint CYP11B2 gene polymorphisms in idiopathic hyperaldosteronism
    P Mulatero
    Department of Medicine and Experimental Oncology, Hypertension Unit, University of Torino, Torino, Italy
    Hypertension 35:694-8. 2000
    ..Our results suggest that variations in the CYP11B2 gene may contribute to dysregulation of aldosterone synthesis and lead to susceptibility to IHA...
  26. doi request reprint Blood pressure levels, left ventricular mass and function are correlated with left atrial volume in mild to moderate hypertensive patients
    A Milan
    Hypertension Unit, Department of Medicine and Experimental Oncology, Division of Internal Medicine, University of Torino, Torino, Italy
    J Hum Hypertens 23:743-50. 2009
    ..These findings highlight the importance of left atrium evaluation in adult, relatively young, essential hypertensive patients...
  27. ncbi request reprint Absence of D147E mutation of CYP11B2 gene in hypertensive patients with increased corticosterone and aldosterone production
    P Mulatero
    Department of Medicine and Experimental Oncology, Hypertension Unit, University of Torino, Italy
    Eur J Endocrinol 144:397-400. 2001
    ..A gene conversion between the CYP11B1 and CYP11B2 genes could be responsible for such a substitution...
  28. ncbi request reprint Angiotensin-converting enzyme and angiotensinogen gene polymorphisms are non-randomly distributed in oral contraceptive-induced hypertension
    P Mulatero
    Department of Medicine and Experimental Oncology, San Vito Hospital, University of Torino, Italy
    J Hypertens 19:713-9. 2001
    ....
  29. ncbi request reprint Rapid cortisol assay during adrenal vein sampling in patients with primary aldosteronism
    Giulio Mengozzi
    Clinical Chemistry Laboratory and Divisions of Radiology, Internal Medicine and Hypertension, Surgery, University of Torino, Torino, Italy
    Clin Chem 53:1968-71. 2007
    ..Technical difficulties with this procedure may be overcome by monitoring cortisol concentrations in the different sampling sites during catheterization...
  30. doi request reprint Primary aldosteronism: who should be screened?
    S Monticone
    Department of Medicine and Experimental Oncology, D ivision of Internal Medicine and Hypertension, University of Torino, Torino, Italy
    Horm Metab Res 44:163-9. 2012
    ....
  31. ncbi request reprint Recent advances in diagnosis and treatment of primary aldosteronism
    F Veglio
    Hypertension Unit, Department of Medicine and Experimental Oncology, S Vito Hospital, University of Turin, Turin, Italy
    Minerva Med 94:259-65. 2003
    ..If bilateral aldosterone excess is demonstrated, an aldosterone receptor antagonist should be administered. This article reviews and discusses the new data about prevalence, diagnosis and treatment of primary aldosteronism...
  32. ncbi request reprint Bradykinin B2 receptor gene (-58T/C) polymorphism influences baroreflex sensitivity in never-treated hypertensive patients
    Alberto Milan
    Department of Medicine and Experimental Oncology, Hypertension Unit, University of Torino, Italy
    J Hypertens 23:63-9. 2005
    ..Recent studies suggest that about 40% of baroreflex variation, an index of cardiac autonomic control, is influenced by genetic factors...
  33. doi request reprint Aldosterone does not modify gene expression in human endothelial cells
    A Verhovez
    Department of Internal Medicine, University of Torino, Torino, Italy
    Horm Metab Res 44:234-8. 2012
    ....
  34. ncbi request reprint Peripheral adrenergic system and hypertension
    F Veglio
    Department of Medicine and Experimental Oncology Hypertension Unit, S. Vito Hospital, Torino, Italy
    Clin Exp Hypertens 23:3-14. 2001
    ..The importance of these findings could provide an assessment of alpha1-peripheral receptors with possible future clinical implications in the pathophysiology and treatment of hypertension...
  35. ncbi request reprint Baroreflex sensitivity is impaired in essential hypertensives with central obesity
    S Del Colle
    Hypertension Unit, Department of Medicine and Experimental Oncology, University of Turin, Molinette Hospital, Turin, Italy
    J Hum Hypertens 21:473-8. 2007
    ..Owing to its association with abdominal fat distribution and subsequently insulin resistance, BRS could represent a further and reliable index for evaluation of global cardiovascular risk in hypertensive patients...
  36. doi request reprint Impairment of cardiovascular autonomic pattern in obese adolescents with Type 2 diabetes mellitus
    F Cerutti
    Department of Pediatrics, University of Turin, Piazza Polonia 96, 10126 Turin, Italy
    J Endocrinol Invest 33:539-43. 2010
    ..In conclusion, T2DM adolescents are characterized by a more marked IR reduced β-cell function in comparison to non-diabetic obese. These modifications may lead to an early impairment of the autonomic pattern...
  37. ncbi request reprint Alpha1-adrenergic receptor subtypes in peripheral blood lymphocytes of essential hypertensives
    F Veglio
    Department of Medicine and Experimental Oncology, Hypertension Unit, University of Turin, Turin, Italy
    J Hypertens 19:1847-54. 2001
    ....
  38. ncbi request reprint Assessing resting heart rate in adolescents: determinants and correlates
    F Rabbia
    Department of Medicine and Experimental Oncology, University of Turin, Italy
    J Hum Hypertens 16:327-32. 2002
    ..In conclusion, resting heart rate in adolescents is related to several methodological, constitutional and environmental factors that have to be taken into account when assessing heart rate values and constructing tables of normal values...
  39. ncbi request reprint Recent advances in diagnosis and treatment of pheochromocytoma
    F Veglio
    Hypertension Unit, Department of Medicine and Experimental Oncology, S Vito Hospital, University of Turin, Turin, Italy
    Minerva Med 94:267-71. 2003
    ..An appropriate pre-, intra- and postoperative medical management of the patient is mandatory. In the absence of optimal medical treatment, intraoperative mortality reaches 50%...
  40. ncbi request reprint Vasoactive hormones induce nitric oxide synthase mRNA expression and nitric oxide production in human endothelial cells and monocytes
    M Schena
    Department of Medicine and Experimental Oncology, University of Turin, Italy
    Am J Hypertens 12:388-97. 1999
    ..Human endothelial cells and monocytes express the NOS-2 and NOS-3 mRNA and the inducible NOS-2 mRNA expression increases after vasoactive hormone stimulation...
  41. doi request reprint Efficacy of antihypertensive treatment based on plasma renin activity: An open label observational study
    Giannina Leotta
    Hypertension Unit, Department of Medicine and Experimental Oncology, University of Turin, Torino, Italy
    Blood Press 19:218-24. 2010
    ....
  42. doi request reprint Primary aldosteronism (PA) and endothelial progenitor cell (EPC) bioavailability
    Andrea Verhovez
    Department of Medicine and Experimental Oncology, Division of Internal Medicine and Hypertension Unit, University of Torino, Torino, Italy
    Clin Endocrinol (Oxf) 69:528-34. 2008
    ..Aldosterone has been reported to decrease EPC proliferation in rats...
  43. ncbi request reprint Effects of birth weight on spontaneous baroreflex sensitivity in adult life
    Giannina Leotta
    Divisione di Medicina Interna e Ipertensione, Ospedale S Vito, Universita di Torino, Strada S Vito 34, 10133 Turin, Italy
    Nutr Metab Cardiovasc Dis 17:303-10. 2007
    ..The objective of the present study was to investigate if baroreflex sensitivity (BRS) in adulthood is associated with birth weight...
  44. doi request reprint Teratocarcinoma-derived growth factor-1 is upregulated in aldosterone-producing adenomas and increases aldosterone secretion and inhibits apoptosis in vitro
    Tracy A Williams
    Department of Medicine and Experimental Oncology, University of Torino, Torino, Italy
    Hypertension 55:1468-75. 2010
    ....
  45. ncbi request reprint Protective effect of spironolactone on endothelial cell apoptosis
    Tracy A Williams
    Department of Medicine and Experimental Oncology, Hypertension Unit, University of Torino, Italy
    Endocrinology 147:2496-505. 2006
    ....
  46. ncbi request reprint Baroreflex sensitivity correlates with left ventricular morphology and diastolic function in essential hypertension
    Alberto Milan
    Department of Medicine and Experimental Oncology, Hypertension Unit, University of Torino, Turin, Italy
    J Hypertens 25:1655-64. 2007
    ..This study sought to assess the association between BRS and left ventricular morphology and function...
  47. ncbi request reprint Diagnosis of primary aldosteronism: from screening to subtype differentiation
    Paolo Mulatero
    Department of Medicine and Experimental Oncology, Hypertension Unit, University of Turin, Turin 10133, Italy
    Trends Endocrinol Metab 16:114-9. 2005
    ....
  48. ncbi request reprint Antihypertensive drugs and the sympathetic nervous system
    Sara Del Colle
    Division of Internal Medicine, Hypertension Unit, Department of Medicine and Experimental Oncology, University of Turin, Molinette Hospital, Turin, Italy
    J Cardiovasc Pharmacol 50:487-96. 2007
    ....
  49. ncbi request reprint Role of HSD11B2 polymorphisms in essential hypertension and the diuretic response to thiazides
    Tracy A Williams
    Hypertension Unit, Department of Medicine and Experimental Oncology, University of Torino, Torino, Italy
    Kidney Int 67:631-7. 2005
    ..Loss-of-function mutations in the gene encoding 11beta HSD2 (HSD11B2) result in overstimulation of the MR and cause salt-sensitive hypertension...
  50. ncbi request reprint [Assessment of cardiovascular risk in hypertensive patients: comparison among scores]
    Sara Del Colle
    Centro per la Diagnosi e la Cura dell Ipertensione Arteriosa, Dipartimento di Medicina e Oncologia Sperimentale, Ospedale San Vito, Torino
    Ital Heart J Suppl 5:694-704. 2004
    ....
  51. ncbi request reprint QT interval in patients with primary aldosteronism and low-renin essential hypertension
    Simona Maule
    Autonomic Unit and Hypertension Unit, Department of Medicine and Experimental Oncology, S Vito Hospital, University of Turin, Turin, Italy
    J Hypertens 24:2459-64. 2006
    ..The aim of the present study was to evaluate the QT interval in patients with primary aldosteronism and low-renin essential hypertension (LREH)...
  52. doi request reprint LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms
    Fulvio Morello
    SCU Medicina d Urgenza, San Giovanni Battista Hospital and Molecular Biotechnology Center, Torino, Italy
    Atherosclerosis 207:38-44. 2009
    ..While oxysterol LXR agonists can increase the endothelial-leukocyte interaction, synthetic LXR agonists are anti-atherogenic and anti-inflammatory. Mechanistic differences may underlie such findings...
  53. ncbi request reprint Salt intake and hypertension therapy
    Alberto Milan
    Department of Medicine and Experimental Oncology, University of Turin, Italy
    J Nephrol 15:1-6. 2002
    ..Reduced sodium intake associated with other dietary changes (such as weight loss, and increasing potassium, calcium and magnesium intake) are important instruments for the prevention and therapy of hypertension...
  54. ncbi request reprint A time-resolved fluoroimmunoassay for 18-oxocortisol and 18-hydroxycortisol. Development of a monoclonal antibody to 18-oxocortisol
    Stefania Morra di Cella
    Department of Internal Medicine, University of Torino, Italy
    J Steroid Biochem Mol Biol 82:83-8. 2002
    ..The TR-FIA technique was more sensitive and had a greater precision than the ELISA technique for both steroids...
  55. doi request reprint Prolonged QT interval and reduced heart rate variability in patients with uncomplicated essential hypertension
    Simona Maule
    Autonomic Unit and Hypertension Unit, Department of Medicine and Experimental Oncology, S Giovanni Battista Hospital, University of Turin, Turin, Italy
    Hypertens Res 31:2003-10. 2008
    ..Further studies are warranted to evaluate whether the combination of such markers can identify hypertensive patients at risk for life-threatening arrhythmias and sudden death. (Hypertens Res 2008; 31: 2003-2010)...
  56. ncbi request reprint Captopril test can give misleading results in patients with suspect primary aldosteronism
    Paolo Mulatero
    Hypertension 50:e26-7. 2007
  57. doi request reprint Letter regarding article by Hood et al, "The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio"
    Paolo Mulatero
    Circulation 117:e151; author reply e152. 2008
  58. ncbi request reprint Prevalence and characteristics of the metabolic syndrome in primary aldosteronism
    Francesco Fallo
    Department of Medical and Surgical Sciences, Universita di Padova, Via Ospedale 105, 35128 Padua, Italy
    J Clin Endocrinol Metab 91:454-9. 2006
    ..Aldosterone excess has been found to be associated with glucose disorders and may contribute to cardiovascular damage...
  59. ncbi request reprint Adiponectin and insulin sensitivity in primary aldosteronism
    Francesco Fallo
    Department of Medical and Surgical Sciences, University of Padova, Padova, Italy
    Am J Hypertens 20:855-61. 2007
    ..We evaluated the relationship between adiponectin and insulin sensitivity in primary aldosteronism, with and without metabolic syndrome, compared with essential hypertension...
  60. doi request reprint Primary aldosteronism, a major form of low renin hypertension: from screening to diagnosis
    Gilberta Giacchetti
    Division of Endocrinology, Universita Politecnica delle Marche, Ancona, 60020, Italy
    Trends Endocrinol Metab 19:104-8. 2008
    ..Finally, subtype forms and lateralization of aldosterone production should be established by bilateral adrenal venous sampling, despite its technical difficulty and varying criteria for success...
  61. ncbi request reprint 11beta-Hydroxysteroid dehydrogenase type 2 activity is associated with left ventricular mass in essential hypertension
    Nicola Glorioso
    Hypertension and Cardiovascular Prevention Centre, ASL n 1 University of Sassari, Italy
    Eur Heart J 26:498-504. 2005
    ..The mineralocorticoid receptor and 11beta-HSD2 are co-expressed in human heart. We investigated whether LVM may be regulated by glucocorticoids in EH patients...
  62. doi request reprint A new form of hereditary primary aldosteronism: familial hyperaldosteronism type III
    Paolo Mulatero
    J Clin Endocrinol Metab 93:2972-4. 2008
  63. doi request reprint Further evidence for linkage of familial hyperaldosteronism type II at chromosome 7p22 in Italian as well as Australian and South American families
    Norlela Sukor
    Endocrine Hypertension Research Center, University of Queensland School of Medicine, Greenslopes Hospital, Brisbane, Australia
    J Hypertens 26:1577-82. 2008
    ....
  64. ncbi request reprint The metabolic syndrome in primary aldosteronism
    Francesco Fallo
    Department of Medical and Surgical Sciences, Clinica Medica 3, University of Padova, Via Ospedale 105, Padova, Italy
    Curr Hypertens Rep 9:106-11. 2007
    ..Higher rates of cardiovascular events reported in primary aldosteronism could be due in part to the increased prevalence of the metabolic syndrome in this disorder...
  65. ncbi request reprint The metabolic syndrome in primary aldosteronism
    Francesco Fallo
    Department of Medical and Surgical Sciences, Clinica Medica 3, University of Padova, Via Ospedale 105, 35128 Padova, Italy
    Curr Diab Rep 8:42-7. 2008
    ..Higher rates of cardiovascular events reported in primary aldosteronism could be due in part to the increased prevalence of the metabolic syndrome in this disorder...