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Genomes and GenesSpecies | P MonteleoneSummaryCountry: Italy Publications
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Dysfunctions of leptin, ghrelin, BDNF and endocannabinoids in eating disorders: beyond the homeostatic control of food intakePalmiero Monteleone
Department of Medicine and Surgery, University of Salerno, Via S Allende, 84084 Baronissi Salerno, Italy
Psychoneuroendocrinology 38:312-30. 2013....
The acute salivary ghrelin response to a psychosocial stress is enhanced in symptomatic patients with bulimia nervosa: a pilot studyPalmiero Monteleone
Chair of Psychiatry, Department of Medicine and Surgery, University of Salerno, Salerno, Italy
Neuropsychobiology 66:230-6. 2012..We hypothesized that symptomatic patients with BN might disclose deranged responses of ghrelin and/or cortisol to stressors and that this could be related to their binge-eating behaviour...
Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot studyPalmiero Monteleone
Department of Psychiatry, Second University of Naples, Largo Madonna delle Grazie, 80138, Naples, Italy
J Clin Endocrinol Metab 97:E917-24. 2012..The physiological mechanisms underlying this eating behavior are not deeply understood, but endogenous rewarding mediators like ghrelin and endocannabinoids are likely involved...
Deranged secretion of ghrelin and obestatin in the cephalic phase of vagal stimulation in women with anorexia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Biol Psychiatry 64:1005-8. 2008..Therefore, we investigated the responses of ghrelin and its recently discovered sibling peptide obestatin to modified sham feeding (MSF) in both AN and healthy women...
Investigation of 3111T/C polymorphism of the CLOCK gene in obese individuals with or without binge eating disorder: association with higher body mass indexPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Neurosci Lett 435:30-3. 2008..Present findings show for the first time that the 3111T/C SNP of the CLOCK gene is not associated to human obesity and/or BED, but it seems to predispose obese individuals to a higher BMI...
The cDNA 385C to A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) is associated with overweight/obesity but not with binge eating disorder in overweight/obese womenPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Psychoneuroendocrinology 33:546-50. 2008....
Decreased levels of serum brain-derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I and II disordersP Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Bipolar Disord 10:95-100. 2008....
Association between A218C polymorphism of the tryptophan-hydroxylase-1 gene, harm avoidance and binge eating behavior in bulimia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Neurosci Lett 421:42-6. 2007....
The Leu72Met polymorphism of the ghrelin gene is significantly associated with binge eating disorderPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Psychiatr Genet 17:13-6. 2007..Genes involved in the ghrelin physiology may therefore contribute to the biological vulnerability to binge eating disorder...
The 196G/A (val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorderPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Italy
Neurosci Lett 406:133-7. 2006..These results suggest that the 196G/A SNP of the human BDNF gene does not contribute to the genetic susceptibility to BN and BED, but may predispose those patients to a more severe binge eating behavior...
No association of the Arg51Gln and Leu72Met polymorphisms of the ghrelin gene with anorexia nervosa or bulimia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Neurosci Lett 398:325-7. 2006..These results suggest that the Arg51Gln and the Leu72Met polymorphisms of the human ghrelin gene do not contribute to the genetic susceptibility to AN and BN...
Investigation of the serotonin transporter regulatory region polymorphism in bulimia nervosa: relationships to harm avoidance, nutritional parameters, and psychiatric comorbidityPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Psychosom Med 68:99-103. 2006....
Association of a functional serotonin transporter gene polymorphism with binge eating disorderPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Am J Med Genet B Neuropsychiatr Genet 141:7-9. 2006..01, CI = 1.33-3.57). Although these data should be regarded as preliminary because of the small size of our sample, they suggest that the 5HTTPRL may contribute to the genetic susceptibility to BED...
Impaired reduction of enhanced levels of dehydroepiandrosterone by oral dexamethasone in anorexia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Psychoneuroendocrinology 31:537-42. 2006..These data support the view that in AN, the increased production of DHEA may be linked to mechanisms other than the enhanced CRF/ACTH drive...
Neuroendocrine dysregulation of food intake in eating disordersPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Regul Pept 149:39-50. 2008..Future studies should clarify whether neuroendocrine alterations are part of the genetically transmitted biological vulnerability to eating disorders...
The circadian basis of mood disorders: recent developments and treatment implicationsPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Large Madonna delle Grazie, Naples, Italy
Eur Neuropsychopharmacol 18:701-11. 2008....
Plasma obestatin, ghrelin, and ghrelin/obestatin ratio are increased in underweight patients with anorexia nervosa but not in symptomatic patients with bulimia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples, Largo Madonna delle Grazie, 80138 Naples, Italy
J Clin Endocrinol Metab 93:4418-21. 2008....
Abnormal diurnal patterns of salivary α-amylase and cortisol secretion in acute patients with anorexia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
World J Biol Psychiatry 12:455-61. 2011..As secondary aim, we measured also salivary cortisol...
Asymmetry of salivary cortisol and α-amylase responses to psychosocial stress in anorexia nervosa but not in bulimia nervosaP Monteleone
Department of Psychiatry, University of Naples SUN, Italy
Psychol Med 41:1963-9. 2011..Therefore, we assessed salivary cortisol and α-amylase responses to the Trier Social Stress Test (TSST) in symptomatic patients with AN and BN compared to healthy controls...
New frontiers in endocrinology of eating disordersPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Curr Top Behav Neurosci 6:189-208. 2011..Moreover, the potential therapeutics of new medications developed on the basis of neuroendocrine aberrations found in EDs is also presented...
Investigation of factors associated to crossover from anorexia nervosa restricting type (ANR) and anorexia nervosa binge-purging type (ANBP) to bulimia nervosa and comparison of bulimia nervosa patients with or without previous ANR or ANBPPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, 80138 Naples, Italy
Compr Psychiatry 52:56-62. 2011....
Circadian rhythms and treatment implications in depressionPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Prog Neuropsychopharmacol Biol Psychiatry 35:1569-74. 2011....
Endocannabinoid Pro129Thr FAAH functional polymorphism but not 1359G/A CNR1 polymorphism is associated with antipsychotic-induced weight gainPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
J Clin Psychopharmacol 30:441-5. 2010..Present findings, although obtained in a small population and in a naturalistic setting, suggest that the cDNA 385C/A SNP of the FAAH gene may predispose subjects to get a clinically meaningful weight gain after antipsychotic exposure...
Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms in bipolar disorder and major depressionPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Pharmacol Res 61:400-4. 2010..These findings, although preliminary, suggest that the CNR1 1359 G/A and the FAAH cDNA 385C to A gene variants may contribute to the susceptibility to mood disorders...
Management of schizophrenia with obesity, metabolic, and endocrinological disordersPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Largo Madonna delle Grazie, 80138, Napoli, Italy
Psychiatr Clin North Am 32:775-94. 2009..Psychiatrists should be aware of metabolic and endocrine side effects of antipsychotics and should make every effort to prevent or minimize them to improve the patients' compliance and quality of life...
Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia nervosa and bulimia nervosa: evidence for synergistic effectsP Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Genes Brain Behav 8:728-32. 2009....
Enhanced ghrelin secretion in the cephalic phase of food ingestion in women with bulimia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Psychoneuroendocrinology 35:284-8. 2010....
Genetic susceptibility to eating disorders: associated polymorphisms and pharmacogenetic suggestionsPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Pharmacogenomics 9:1487-520. 2008..Future studies should focus on more homogeneous subgroups, either relying on specific ED traits or identifying endophenotypes. This will be useful also for prevention and treatment of EDs...
Circulating brain-derived neurotrophic factor is decreased in women with anorexia and bulimia nervosa but not in women with binge-eating disorder: relationships to co-morbid depression, psychopathology and hormonal variablesPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Psychol Med 35:897-905. 2005..In the present study, we investigated serum levels of BDNF in patients with anorexia nervosa (AN), bulimia nervosa (BN) and binge-eating disorder (BED)...
Circulating leptin in patients with anorexia nervosa, bulimia nervosa or binge-eating disorder: relationship to body weight, eating patterns, psychopathology and endocrine changesP Monteleone
Institute of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138, Naples, Italy
Psychiatry Res 94:121-9. 2000....
Intestinal permeability is decreased in anorexia nervosaP Monteleone
Department of Psychiatry, University of Naples S U N, Naples, Italy
Mol Psychiatry 9:76-80. 2004..Since IP reflects the anatomo-functional status of intestinal mucosa, the present findings support the idea that changes in the anatomo-physiology of intestinal mucosa occur in anorexia nervosa...
Opposite changes in circulating adiponectin in women with bulimia nervosa or binge eating disorderPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, 80138 Naples, Italy
J Clin Endocrinol Metab 88:5387-91. 2003....
Differential responses of circulating ghrelin to high-fat or high-carbohydrate meal in healthy womenPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, 80138 Naples, Italy
J Clin Endocrinol Metab 88:5510-4. 2003..007). These findings show that circulating ghrelin is differently suppressed by diet manipulations. The mechanisms responsible for such a phenomenon and its possible implication in the physiology of human satiety remain to be elucidated...
Circulating levels of neuroactive steroids in patients with binge eating disorder: a comparison with nonobese healthy controls and non-binge eating obese subjectsPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Int J Eat Disord 34:432-40. 2003..To assess whether those changes are related to malnutrition, we investigated plasma levels of neuroactive steroids in women with binge eating disorder (BED) who compulsively binge as bulimic patients, but do not incur malnutrition...
Altered immunoreactive levels of G proteins in peripheral mononuclear cells of patients with anorexia nervosa and bulimia nervosaP Monteleone
Department of Psychiatry, University of Naples S U N, Naples, Italy
Mol Psychiatry 8:680-4. 2003..These findings, although obtained in peripheral blood cells, may suggest a derangement of G protein-mediated signal transduction in the pathophysiology of eating disorders...
Leptin secretion is related to chronicity and severity of the illness in bulimia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Psychosom Med 64:874-9. 2002....
Correlations between negative symptoms and peripheral G protein levels in mononuclear leukocytes of deficit and nondeficit schizophrenics. Preliminary resultsPalmiero Monteleone
Department of Psychiatry, University of Naples S U N, Largo Madonna delle Grazie, 80138 Naples, Italy
Eur Arch Psychiatry Clin Neurosci 252:214-8. 2002..These results must be regarded as preliminary because of the possible interference of antipsychotic drugs on the explored parameters...
Pronounced early increase in circulating leptin predicts a lower weight gain during clozapine treatmentPalmiero Monteleone
Institute of Psychiatry, University of Naples SUN, Naples, Italy
J Clin Psychopharmacol 22:424-6. 2002..These findings suggest that early changes in leptin secretion may predict long-term weight gain in the course of clozapine administration...
Opposite modifications in circulating leptin and soluble leptin receptor across the eating disorder spectrumP Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Mol Psychiatry 7:641-6. 2002..The relevance of these findings to the pathophysiology and treatment of eating disorders remains to be elucidated...
Plasma levels of neuroactive steroids are increased in untreated women with anorexia nervosa or bulimia nervosaP Monteleone
Institute of Psychiatry, University of Naples SUN, Italy
Psychosom Med 63:62-8. 2001..Therefore, we measured plasma levels of DHEA, DHEA-S, 3alpha,5alpha-THP and other hormones in patients with AN or BN and explored possible relationships between neuroactive steroids and psychopathology...
Aggressive behavioral characteristics and endogenous hormones in women with Bulimia nervosaP Cotrufo
Institute of Psychiatry, University of Naples SUN, Naples, Italy
Neuropsychobiology 42:58-61. 2000..These findings suggest that in BN, increased plasma levels of testosterone may play a role in the modulation of aggressiveness...
Plamsa leptin response to acute fasting and refeeding in untreated women with bulimia nervosaP Monteleone
Institute of Psychiatry, University of Naples SUN, Italy
J Clin Endocrinol Metab 85:2499-503. 2000..We conclude that in untreated women with BN, leptin, despite its very low plasma values, still holds its function as a sensor of body weight changes, but loses its role of signaling acute changes in energy balance...
Leptin functioning in eating disordersPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
CNS Spectr 9:523-9. 2004..However, malnutrition-induced alterations in its physiology may contribute to the genesis and/or the maintenance of some clinical manifestations of AN and BN and may have an impact on the prognosis of AN...
Opposite changes in the serum brain-derived neurotrophic factor in anorexia nervosa and obesityPalmiero Monteleone
Department of Psychiatry, Institution University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Psychosom Med 66:744-8. 2004..Therefore, the possibility exists that alterations in BDNF production and/or activity are involved in the pathophysiology of anorexia nervosa (AN) and obesity...
Circulating ghrelin is decreased in non-obese and obese women with binge eating disorder as well as in obese non-binge eating women, but not in patients with bulimia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Psychoneuroendocrinology 30:243-50. 2005..The reduction of plasma ghrelin in non-obese and obese binge eaters as well as in obese non-binge eaters may represent a secondary change aiming to counteract their positive energy imbalance...
Investigation of peptide YY and ghrelin responses to a test meal in bulimia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Biol Psychiatry 57:926-31. 2005..Therefore, we aimed to assess plasma PYY and ghrelin responses to a test meal in symptomatic bulimics...
Long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and THDOC in patients with schizophrenia: a preliminary studyPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
J Clin Psychopharmacol 24:437-40. 2004....
Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosaPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Neuropsychopharmacology 30:1216-21. 2005....
Enhanced serum cholesterol and triglyceride levels in bulimia nervosa: relationships to psychiatric comorbidity, psychopathology and hormonal variablesPalmiero Monteleone
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Psychiatry Res 134:267-73. 2005..This alteration may be involved in the pathophysiology of certain psychopathological characteristics of BN and cannot be explained by the co-occurrence of other psychiatric disorders...
Ghrelin and leptin responses to food ingestion in bulimia nervosa: implications for binge-eating and compensatory behavioursP Monteleone
Department of Psychiatry, University of Naples SUN, Naples, Italy
Psychol Med 33:1387-94. 2003..The blunted ghrelin response to food ingestion may support the occurrence in bulimic subjects of an impaired suppression of the drive to eat following a meal. This may have implications for binge-eating...
Olanzapine-induced weight gain in anorexia nervosa: involvement of leptin and ghrelin secretion?F Brambilla
Department of Psychiatry, University of Naples SUN, Naples, Italy
Psychoneuroendocrinology 32:402-6. 2007..Aim of this study was to determine whether in patients with Anorexia Nervosa (AN) OLA induces weight gain through the modulation of the hunger-satiety regulatory peptides leptin and ghrelin...
Neurocognitive functioning in subjects with eating disorders: the influence of neuroactive steroidsSilvana Galderisi
Department of Psychiatry, University of Naples SUN, Italy
Biol Psychiatry 53:921-7. 2003..CONCLUSIONS: A subtle impairment of noneffortful learning is the only neuropsychological deficit in patients with EDs. Changes in neuroactive steroids influence neurocognitive performance...
The 3111T/C polymorphism of the CLOCK gene confers a predisposition to a lifetime lower body weight in patients with anorexia nervosa and bulimia nervosa: a preliminary studyAlfonso Tortorella
Department of Psychiatry, University of Naples SUN, Naples, Italy
Am J Med Genet B Neuropsychiatr Genet 144:992-5. 2007....
Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cellsI Matias
Endocannabinoid Research Group, Institute of Biomolecular Chemistry National Research Council, Naples, Italy
Br J Pharmacol 152:676-90. 2007..In beta-cells and human blood, OEA and PEA are down- or up-regulated under conditions of transient or chronic hyperglycaemia, respectively...
Plasma concentrations of amino acids in chronic schizophrenics treated with clozapineA Tortorella
Institute of Psychiatry, University of Naples SUN, Naples, Italy
Neuropsychobiology 44:167-71. 2001..These data show changes in serum amino acids that may influence central serotonergic, dopaminergic and glutamatergic transmission in neuroleptic-resistant schizophrenics...
Different temperament and character dimensions correlate with panic disorder comorbidity in bipolar disorder and unipolar depressionMarco Mula
Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Via Roma 67, 56100 Pisa, Italy
J Anxiety Disord 22:1421-6. 2008..This study aimed to investigate temperament and character correlates of panic disorder (PD) comorbidity in euthymic patients with bipolar disorder (BD) or unipolar depression (UD)...
Interleukin-1beta and tumor necrosis factor-alpha in children with major depressive disorder or dysthymiaF Brambilla
Clinica Psichiatrica dell Università, SUN, Naples, Italy
J Affect Disord 78:273-7. 2004..The aim of our study was to see whether or not cytokine secretion is impaired at a very young phase of development of depressive disorders, possibly being pathogenetically involved in their course...
Hormone replacement therapy and endometrial, ovarian and colorectal cancerM Gambacciani
Department of Reproductive Medicine and Child Development, Division of Obstetrics and Gynecology, Via Roma 35, Pisa, Italy
Best Pract Res Clin Endocrinol Metab 17:139-47. 2003..The future of HRT in post-menopausal women lies in the individualization of the therapy based upon personal risk factors and characteristics...
Clinical usefulness of endometrial screening by ultrasound in asymptomatic postmenopausal womenM Gambacciani
Department of Obstetrics and Gynecology Piero Fioretti, University Pisa, Via Roma 67, Pisa 56126, Italy
Maturitas 48:421-4. 2004..The aim of the present study was to evaluate the clinical usefulness of routine use of endometrial ultrasound in asymptomatic, bleeding-free postmenopausal women...
Persistent amenorrhoea in weight-recovered anorexics: psychological and biological aspectsFrancesca Brambilla
Istituto di Clinica Psichiatrica, Universita, SUN, Naples, Italy
Psychiatry Res 118:249-57. 2003....
Olanzapine therapy in anorexia nervosa: psychobiological effectsFrancesca Brambilla
Department Mental Health, Sacco Hospital, Milan, Italy
Int Clin Psychopharmacol 22:197-204. 2007..No correlations were observed between homovanilic acid concentrations and psychopathological parameters. The pharmacological treatment can significantly improve specific aspects of anorexia nervosa...
Is the time course of clozapine response correlated to the time course of clozapine plasma levels? A one-year prospective study in drug-resistant patients with schizophreniaMichele Fabrazzo
Institute of Psychiatry, University of Naples SUN, Naples, Italy
Neuropsychopharmacology 27:1050-5. 2002..The present findings show, for the first time, that the time course of the clinical response to clozapine may be linked to the time course of plasma levels of clozapine and its major metabolites...
Glucagon-like peptide-1 secretion in bulimia nervosaFrancesca Brambilla
Department of Mental Health, Naples University SUN, Largo Madonna delle Grazie, Naples 80138, Italy
Psychiatry Res 169:82-5. 2009..GLP-1 levels correlated positively with bingeing-vomiting frequency, with B.I.T.E. scores and the "bulimia" subitem scores of the EDI-2 scale, and negatively with the "ascetism" subitem score of the same scale...
Melanocortin-4 receptor molecular scanning and pro-opiomelanocortin R236G variant screening in binge eating disorderAlfonso Tortorella
Department of Psychiatry, University of Naples SUN, Naples, Italy
Psychiatr Genet 15:161. 2005
Pharmacological activation of the GABAergic system does not affect GH and PRL release in acromegalyF Orio
Department of Endocrinology, General Hospital of Eboli, Salerno, Italy
Horm Metab Res 20:701-4. 1988..These results suggest that the response of GH and PRL to SV in acromegaly is qualitatively different from normal controls...
Neurocognitive functioning in bulimia nervosa: the role of neuroendocrine, personality and clinical aspectsS Galderisi
Department of Psychiatry, University of Naples SUN, Naples, Italy
Psychol Med 41:839-48. 2011....
Self-injurious behavior and attempted suicide in purging bulimia nervosa: associations with psychiatric comorbidityAngela Favaro
Department of Neurosciences, University of Padova, Padova, Italy
J Affect Disord 105:285-9. 2008..The aim of the present study was to investigate the axis I and II comorbidity in subjects with bulimia nervosa who report self-injurious behavior and/or suicide attempt...
Plasma leptin and antipsychotic-induced body weight gainPalmiero Monteleone
Neuropsychopharmacology 30:1769; author reply 1770-1. 2005
Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemiaIsabel Matias
Endocannabinoid Research Group, Institute of Biomolecular Chemistry of the National Research Council, Via Campi Flegrei 34, 80078 Pozzuoli (Naples, Italy
J Clin Endocrinol Metab 91:3171-80. 2006..CONCLUSIONS: Peripheral endocannabinoid overactivity might explain why CB(1) blockers cause weight-loss independent reduction of lipogenesis, of hypoadiponectinemia, and of hyperinsulinemia in obese animals and humans...
Aripiprazole in the treatment of schizophrenia: a consensus report produced by schizophrenia experts in ItalyGiovan B Cassano
Universita di Pisa, Casa di Cura S Rossore Viale delle Cascine, Pisa, Italy
Clin Drug Investig 27:1-13. 2007..Switching to aripiprazole from maintenance therapy with another antipsychotic also works well, provided the change is made gradually, involving tapering of the original medication...
Health-related quality of life in euthymic bipolar disorder patients: differences between bipolar I and II subtypesGiuseppe Maina
Department of Neurosciences, Mood and Anxiety Disorders Unit, University of Turin, Italy
J Clin Psychiatry 68:207-12. 2007..We included as comparison samples a group of subjects with recurrent major depression (RMD) and a group of non-psychiatrically ill individuals...
