Research Topics
| V MollaceSummaryCountry: Italy Publications
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Publications
N-acetylcysteine prevents HIV gp 120-related damage of human cultured astrocytes: correlation with glutamine synthase dysfunctionValeria Visalli
Department of Pharmacobiological Sciences, Faculty of Pharmacy, University Magna Graecia, Catanzaro, Italy
BMC Neurosci 8:106. 2007....
Apoptosis and telomeres shortening related to HIV-1 induced oxidative stress in an astrocytoma cell lineMichela Pollicita
Department of Experimental Medicine and Biochemical Sciences, University Tor Vergata, Rome, Italy
BMC Neurosci 10:51. 2009..In the present study we analyzed the potential relations occurring between free radicals formation and telomere length during HIV-1 mediated astroglial death...
Peroxynitrite decomposition catalyst prevents apoptotic cell death in a human astrocytoma cell line incubated with supernatants of HIV-infected macrophagesCarolina Muscoli
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Roccelletta di Borgia, Catanzaro, Italy
BMC Neurosci 3:13. 2002..Here we investigated the role of peroxynitrite in apoptosis occurring in astroglial cells incubated with supernatants of HIV-infected human primary macrophages (M/M)...
Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidantsV Mollace
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Roccelletta di Borgia, Catanzaro, Italy
Trends Neurosci 24:411-6. 2001..Thus, a better understanding of the processes that trigger and modulate free radical formation in brain tissues of AIDS patients might help in a successful therapeutic approach to the neuropathogenesis of HIV infection...
The protective effect of bergamot oil extract on lecitine-like oxyLDL receptor-1 expression in balloon injury-related neointima formationVincenzo Mollace
University Magna Graecia of Catanzaro, Italy
J Cardiovasc Pharmacol Ther 13:120-9. 2008..These results suggest that natural antioxidants may be relevant in the treatment of vascular disorders in which proliferation of SMCs and oxyLDL-related endothelial cell dysfunction are involved...
Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studiesVincenzo Mollace
Faculty of Pharmacy, Department of Pharmacobiological Sciences, University Magna Graecia, Catanzaro, Italy
Fitoterapia 82:309-16. 2011..Moreover, BPF inhibited HMG-CoA reductase activity and enhanced reactive vasodilation thus representing an efficient phytotherapeutic approach in combating hyperlipemic and hyperglycaemic disorders...
The protective effect of M40401, a superoxide dismutase mimetic, on post-ischemic brain damage in Mongolian gerbilsVincenzo Mollace
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Roccelletta di Borgia, Catanzaro, Italy
BMC Pharmacol 3:8. 2003..Here we studied the effect of a low molecular weight superoxide dismutase mimetic (M40401) in brain damage subsequent to ischemia-reperfusion injury in Mongolian gerbils...
The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimeticVincenzo Mollace
Department of Pharmacobiological Sciences, University of Catanzaro Magna Graecia, Complesso NinĂ Barbieri 88021, Roccelletta di Borgia CZ, Italy
Neurosci Lett 335:163-6. 2003..Taken together, these results demonstrate that paraquat produces brain damage via abnormal formation of oxygen free radicals and that this effect may be counteracted by novel SOD mimetics...
The contribution of oxidative stress in apoptosis of human-cultured astroglial cells induced by supernatants of HIV-1-infected macrophagesVincenzo Mollace
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Roccelletta di Borgia, Italy
J Leukoc Biol 71:65-72. 2002....
Dexamethasone inhibits the inducible bioconversion of glyceryl trinitrate to nitric oxideVincenzo Mollace
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Complesso Nini Barbieri, Roccelletta di Borgia, 88100 Catanzaro, Italy
J Cardiovasc Pharmacol 39:544-51. 2002....
Central cardiovascular responses induced by interleukin 1 beta and tumor necrosis factor alpha infused into nucleus tractus solitarii, nucleus parabrachialis medialis and third cerebral ventricle of normotensive ratsV Mollace
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Roccelletta di Borgia, 89100 Catanzaro, Italy
Neurosci Lett 314:53-6. 2001..This effect is potentiated by LPS and this may explain the alteration in cardiovascular regulation which can be observed in diseases in which an excess of circulating endotoxins and cytokines may occur...
Ethanol-induced injury in rat primary cortical astrocytes involves oxidative stress: effect of idebenoneCarolina Muscoli
Department of Pharmacobiological Sciences, University of Catanzaro Magna Graecia, , I-88021 Roccelletta di Borgia, Catanzaro, Italy
Neurosci Lett 329:21-4. 2002....
The role of nitrinergic connections in central cardiovascular responses mediated by physostigmine infused into posterior hypothalamusErnesto Palma
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Roccelletta di Borgia, 88100 Catanzaro, Italy
Neurosci Lett 368:112-5. 2004....
The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: role of the lectin-like oxidized low-density lipoprotein receptor-1Carolina Muscoli
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Complesso Nini' Barbieri, Roccelletta di Borgia, 88100, Catanzaro, Italy
J Pharmacol Exp Ther 311:44-50. 2004....
The contribution of peroxynitrite generation in HIV replication in human primary macrophagesStefano Aquaro
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Roccelletta di Borgia, Catanzaro, Italy
Retrovirology 4:76. 2007..MnTBAP (Mn(III)tetrakis(4-benzoic acid)porphrin chloride), a synthetic peroxynitrite decomposition catalyst, reduced oxidative stress subsequent to peroxynitrite generation...
Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in miceCarolina Muscoli
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Roccelletta di Borgia, Catanzaro, Italy
J Clin Invest 117:3530-9. 2007..Peroxynitrite (ONOO-) decomposition catalysts may have therapeutic potential as adjuncts to opiates in relieving suffering from chronic pain...
The effect of inflammatory stimuli on NMDA-related activation of glutamine synthase in human cultured astroglial cellsCarolina Muscoli
Faculty of Pharmacy, Magna Graecia University of Catanzaro, Complesso Nini' Barbieri, Roccelletta di Borgia, 88100 Catanzaro, Italy
Neurosci Lett 373:184-8. 2005....
Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donorsVincenzo Mollace
Faculty of Pharmacy, University of Catanzaro Magna Graecia, Roccelletta di Borgia, Catanazaro, Italy
Pharmacol Rev 57:217-52. 2005....
A newly identified role for superoxide in inflammatory painZhi-Qiang Wang
Department of Biological and Pharmacological Research, MetaPhore Pharmaceuticals, 1910 Innerbelt Business Center Drive, St. Louis, MO 63114, USA
J Pharmacol Exp Ther 309:869-78. 2004..The discovery of this pathway opens a new therapeutic strategy for the development of novel nonnarcotic antihyperalgesic agents...
Superoxide-mediated nitration of spinal manganese superoxide dismutase: a novel pathway in N-methyl-D-aspartate-mediated hyperalgesiaCarolina Muscoli
MetaPhore Pharmaceuticals, Inc, 1910 Innerbelt Business Center Drive, St Louis, MO 63114, USA
Pain 111:96-103. 2004..The broader implication of our findings is that superoxide may contribute to various forms of pain events that are driven by NMDA-receptor activation...
