Giampiero Mazzaglia

..Therefore, in choosing the more cost-effective approach to collect data such evidence should be taken into account, and results should be interpreted with great caution...

..In conclusion, the study results appear to suggest that the prescribing patterns of Italian GPs and the predictors of different antihyperglycemic drug use are consistent with recent scientific evidence...

..Underuse and discontinuation of OAC treatment is common in incident AF patients. Risk stratification only partially influences AT management...

..To describe patterns of persistence and related primary care costs associated with first antihypertensive treatment...

..We explored predictors of adherence to antihypertensive treatment and the association of adherence with acute cardiovascular events...

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..Little is known about long-term utilization of drugs related to cardiovascular secondary prevention in everyday practice...

..However, the benefits of aspirin might be affected by its inappropriate use. Real-life information on aspirin use is therefore needed as an audit tool aimed to maximize the benefits and minimize the risks...

..CONCLUSIONS: The prevalence of MI diagnosis in the HSD is very close to that obtained by other epidemiological methods. Querying the database can provide a simple and inexpensive way to estimate and monitor the prevalence of MI in Italy...

..CONCLUSIONS: These findings provide evidence for the effect of an electronic reminder in affecting the prescriptive behavior of GPs...

..To characterize the epidemiology of disability in, and the level of care available to, older community-dwellers in an Italian urban sample...

..However a relatively large number of patients (646) with high plasma lipids remained untreated. CONCLUSIONS: Monitoring and intervention strategies on plasma lipid levels in patients with a diagnosis of stroke or TIA need to be improved...

..7%). CONCLUSIONS: Approximately 370,000 patients are prescribed with OAs in Italy and for more than 50% of them life-long therapy is recommended. Atrial fibrillation is the most frequent reason for prescription...

..CONCLUSIONS: Prescription data from general practice databases may be a valid, simple, and cost-effective method to evaluate and serially monitor the prevalence of AP...

..Incidence is of paramount importance when cost-effectiveness rate of actions against SCD must be estimated...

..Time trends of suboptimal prescribing in older, community dwellers have been poorly investigated, particularly in Italy...

..This is a very old group of subjects with heavy co-morbidity and a high need for continuous, prolonged assistance. Studies specifically aimed at the care of HF patients are needed...

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..New strategies aimed at improving secondary cardiovascular prevention among these easily identifiable high-risk subjects are needed...

..All of these patients should have been prescribed antiplatelet drugs or anticoagulant agents, except in cases of extremely short life expectancy or substantial contraindications...

..To develop and validate mortality and hospitalization prognostic tools based upon information readily available to primary care physicians (PCPs)...

..PSA screening practice has continued to increase in Italy and is often performed in elderly people without any scientific rationale...

..This experience, although obtained in a limited geographic area, could help improve the efficacy and safety of OAT management...

..To compare the ability of five measures of comorbidity to predict mortality and incident disability in basic activities of daily living (BADLs) in unselected older persons...

..The aim of this study was to reassess the safety profiles of fluoroquinolones using the database of the Italian Interregional Group of Pharmacovigilance (IGP) and the administrative data of fluoroquinolone prescriptions...

..To explore the antibiotic prescribing pattern for cystitis and the patient-related variables associated with prescription during a 4 year period among Italian general practitioners (GPs)...

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..5%). The withdrawal rate was not significantly different between the groups. Manidipine is equally safe and effective as nifedipine and it may have more activity on renal function and less severe side effects compared to nifedipine...

..To determine the prevalence of concomitant use of drugs potentially responsible for interactions among itraconazole and fluconazole users in general practice...

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..4 (95% confidence interval 6.3-24.5), 20.4 (6.9-60.3), 18.7 (8.2-42.8) and 33.7 (9.2-123.6), respectively, with no significant differences when compared to each other...

..To assess the antipsychotic use and the prevalence/incidence of antipsychotic drug users in Italy during the years 1999-2002. To estimate the persistence with antipsychotic medications, and to measure their off-label use...

..We therefore carried out a study to determine ADE incidence and ADE-related hospital admissions among emergency department (ED) visits, and to identify the risk factors for serious ADE leading to ED visit...

..Although general practitioners (GPs) represent the first line for identification of these high-risk patients, their diagnostic approach to CKD is ill defined...

..46 times for atypicals. Clinicians should be cautious in prescribing phenotiazines and butyrophenones in elderly patients, since the risk for stroke would seem comparable or even greater than with atypicals...

..To verify General Practitioners (GPs) compliance to the recommended laboratory monitoring for statin users...